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Obtain estimated marginal means (EMMs) for many linear, generalized linear, and mixed models. Compute contrasts or linear functions of EMMs, trends, and comparisons of slopes. Plots and other displays. Least-squares means are discussed, and the term "estimated marginal means" is suggested, in Searle, Speed, and Milliken (1980) Population marginal means in the linear model: An alternative to least squares means, The American Statistician 34(4), 216-221 <<a href="https://doi.org/10.1080%2F00031305.1980.10483031" target="_top">doi:10.1080/00031305.1980.10483031</a>>.
Researchers solved the mystery of how soft lithium dendrites crack the hard ceramic inside solid-state batteries, triggering short circuits。 The breakthrough could help engineers build safer, longer-lasting batteries for smartphones, electric vehicles, and other electronics
Researchers have created self-destructing living plastic that uses engineered bacteria to completely break itself down when activated。 The material degrades in just six days without creating microplastics, offering a potential new solution for single-use plastic waste
This article presents global cancer statistics by world region for the year 2022 based on updated estimates from the International Agency for Research on Cancer (IARC). There were close to 20 million new cases of cancer in the year 2022 (including nonmelanoma skin cancers [NMSCs]) alongside 9.7 million deaths from cancer (including NMSC). The estimates suggest that approximately one in five men or women develop cancer in a lifetime, whereas around one in nine men and one in 12 women die from it. Lung cancer was the most frequently diagnosed cancer in 2022, responsible for almost 2.5 million new cases, or one in eight cancers worldwide (12.4% of all cancers globally), followed by cancers of the female breast (11.6%), colorectum (9.6%), prostate (7.3%), and stomach (4.9%). Lung cancer was also the leading cause of cancer death, with an estimated 1.8 million deaths (18.7%), followed by colorectal (9.3%), liver (7.8%), female breast (6.9%), and stomach (6.8%) cancers. Breast cancer and lung cancer were the most frequent cancers in women and men, respectively (both cases and deaths). Incidence rates (including NMSC) varied from four-fold to five-fold across world regions, from over 500 in Australia/New Zealand (507.9 per 100,000) to under 100 in Western Africa (97.1 per 100,000) among men, and from over 400 in Australia/New Zealand (410.5 per 100,000) to close to 100 in South-Central Asia (103.3 per 100,000) among women. The authors examine the geographic variability across 20 world regions for the 10 leading cancer types, discussing recent trends, the underlying determinants, and the prospects for global cancer prevention and control. With demographics-based predictions indicating that the number of new cases of cancer will reach 35 million by 2050, investments in prevention, including the targeting of key risk factors for cancer (including smoking, overweight and obesity, and infection), could avert millions of future cancer diagnoses and save many lives worldwide, bringing huge economic as well as societal dividends to countries over the forthcoming decades.
Researchers discovered that electricity can dramatically reshape how heat flows through certain ceramic materials, increasing heat conduction by almost threefold in a preferred direction。 The unexpected result could lead to much more efficient cooling technologies and energy-saving devices
Scientists have identified new clues that could help astronomers spot one of the most famous hypothetical alien megastructures: a Dyson sphere。 The study finds that red dwarfs and white dwarfs are the most promising stars to examine, since advanced civilizations could potentially build energy-harvesting swarms around them more easily。 These objects
Astronomers have uncovered 31 of the oldest known quasars, including the two earliest ever detected, shining from a time when the universe was only about 670 million years old。 Powered by supermassive black holes billions of times the Sun’s mass, these incredibly bright objects challenge scientists’ understanding of how such enormous black holes fo
Scientists at Nanyang Technological University in Singapore have discovered a surprisingly simple way to create exotic light structures called optical skyrmions using a 200-year-old optical effect known as the Poisson spot。 Instead of relying on expensive, highly engineered materials, they simply shine a laser at a tiny circular disc, producing sta
Researchers have achieved a major milestone by creating a long-sought two-dimensional quantum material and confirming its unusual conducting edge states。 The ability to control these states through strain could make the material a promising platform for future room-temperature quantum electronics
A newly developed material can control and "program" heat, allowing it to direct thermal radiation, switch modes, and remember its settings without continuous power。 The innovation could lead to smarter infrared sensors, better energy technologies, and memory devices that use light and heat instead of electrical charges
NASA's Perseverance rover has reached an impressive new milestone on Mars, completing the equivalent of a full marathon by driving 26。2 miles (42。195 kilometers) across the Red Planet
NASA's PACE satellite captured the Black Sea glowing turquoise during its annual phytoplankton bloom。 The vivid color comes from massive numbers of coccolithophores, microscopic organisms whose reflective shells brighten the water enough to be seen from space。 An astronaut aboard the International Space Station also photographed the bloom spreading
JWST has captured unusually detailed images of gas feeding the supermassive black hole at the center of NGC 4696。 A vast filament appears to funnel material into an 800-light-year-wide spinning disk, where gas races around at up to 600 kilometers per second。 The findings suggest black holes may recycle their own fuel by heating gas with jets and la
Physicists from Heinrich Heine University Düsseldorf (HHU) have examined a fundamental property of quantum mechanics in collaboration with the German Aerospace Center (DLR)。 In the scientific journal Physical Review Letters, they show that this theory does not necessarily need to be formulated with imaginary numbers – real numbers can in fact also
The hunt for ancient life on Mars just got an important test run。 Scientists confirmed that the Rosalind Franklin rover's sophisticated instrument can detect subtle differences in two stable molecules that could preserve evidence of past life for billions of years。 But the team also uncovered a surprise: organic molecules in the Murchison meteorite