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The medical effects of modest weight reduction (approximately 10% or less) in patients with obesity-associated medical complications were reviewed. The National Library of Medicine MEDLINE database and the Derwent RINGDOC database were searched to identify English language studies that examined the effects of weight loss in obese patients with serious medical complications commonly associated with obesity (non-insulin dependent diabetes mellitus (NIDDM or type II), hypertension, hyperlipidemia, hypercholesterolemia, and cardiovascular disease). Studies in which patients experienced approximately 10% or less weight reduction were selected for review. Studies indicated that, for obese patients with NIDDM, hypertension or hyperlipidemia, modest weight reduction appeared to improve glycemic control, reduce blood pressure, and reduce cholesterol levels, respectively. Modest weight reduction also appeared to increase longevity in obese individuals. In conclusion, a large proportion of obese individuals with NIDDM, hypertension, and hyperlipidemia experienced positive health benefits with modest weight loss. For patients who are unable to attain and maintain substantial weight reduction, modest weight loss should be recommended; even a small amount of weight loss appears to benefit a substantial subset of obese patients.

By analyzing over 400,000 Reddit posts, researchers discovered that users of popular GLP-1 weight-loss drugs frequently discussed unexpected symptoms like menstrual irregularities, chills, and hot flashes。 The findings suggest AI could turn social media into a powerful early-warning system for spotting side effects that clinical trials may miss

Researchers have discovered how microscopic imperfections and atomic vibrations can be used to control a powerful quantum effect in an advanced material。 The effect can turn alternating electrical signals from the environment directly into the kind of current electronic devices need, without traditional components。 As temperature changes, the signa

Astronomers have finally cracked the mystery behind a strange class of repeating cosmic signals that has baffled scientists for years。 Using Australia’s ASKAP radio telescope, researchers traced the bursts to a rare stellar duo in which a dense white dwarf is relentlessly siphoning material from a nearby red dwarf companion。 As the stolen matter sp

June's night sky delivers several must-see events, starting with a close encounter between Venus and Jupiter after sunset。 Mercury joins the pair to form a rare three-planet lineup, while the Moon puts on a special show by passing in front of Venus for viewers in parts of the Americas。 The month also marks the start of astronomical summer and the r

NASA’s futuristic X-59 jet is about to face its biggest challenge yet: breaking the sound barrier for the first time。 After a successful series of test flights that pushed the aircraft to near-supersonic speeds, engineers are preparing to fly it faster than Mach 1 and eventually up to Mach 1。6 at 60,000 feet

Scientists have proposed a new method for finding tightly bound supermassive black hole pairs by searching for stars that flash repeatedly as their light is magnified by the black holes’ gravity。 The timing and brightness of these bursts could provide a unique fingerprint of black holes slowly spiraling toward a future collision

NASA's James Webb Space Telescope has uncovered unusual chemistry in interstellar comet 3I/ATLAS, including the first direct detection of methane on a visitor from another star system。 The comet also contains exceptionally high levels of carbon dioxide, making it unlike most comets born in our solar system。 Scientists believe the methane was hidden

Scientists have developed a solar desalination system that turns seawater into drinking water without creating environmentally damaging brine。 Special laser-textured metal panels use sunlight to evaporate water while automatically moving salt deposits away from the working surface, preventing clogging。 The process was successfully tested with water

A new room-temperature quantum device uses twisted light to entangle photons and electrons, overcoming one of the biggest hurdles in quantum technology。 The breakthrough could pave the way for smaller, cheaper quantum systems with applications ranging from secure communications to future AI and computing platforms

A team at the University of Chicago has discovered a surprisingly simple way to create powerful quantum states that are normally difficult to produce。 By making small adjustments to the energy levels of atoms inside an optical cavity, researchers can generate a wide variety of highly entangled states without adding complicated hardware

Researchers at EPFL have developed a chip-scale ultrafast laser that performs on par with traditional tabletop femtosecond lasers。 The innovation could make advanced laser technologies far smaller, cheaper, and more accessible for applications ranging from medical diagnostics to atomic clocks

"We look forward to working with Roscosmos on a collaborative approach to address the leaks

SpaceX won’t get easy access to billions of dollars from passive investors

Scientists have uncovered a surprising force that may help explain how binary star systems form so quickly。 New supercomputer simulations show that magnetic fields surrounding newborn stars can act like a cosmic brake, stripping away angular momentum and allowing two still-forming protostars to spiral closer together instead of drifting apart

Researchers discovered a way to reverse the direction of energy flow in turbulence, challenging a theory that has stood for more than 80 years。 The finding could open new possibilities for controlling ocean currents, improving medical technologies, and enhancing climate forecasting

Those ousted included ADA journal editor-in-chief Steven Kahn and former ADA president Desmond Schatz

Developer felt "beaten up," with "no choice" but to shrink data center