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The Alzheimer's Disease Neuroimaging Initiative (ADNI) provides a comprehensive multimodal neuroimaging resource for studying aging and Alzheimer's disease (AD). Since its second wave, ADNI has increasingly collected resting-state functional MRI (rs-fMRI), a valuable resource for discovering brain connectivity changes predictive of cognitive decline and AD. A major barrier to its use is the considerable variability in acquisition protocols and data quality, compounded by missing imaging sessions and inconsistencies in how functional scans temporally align with clinical assessments. As a result, many studies only utilize a small subset of the total rs-fMRI data, limiting statistical power, reproducibility, and the ability to study longitudinal functional brain changes at scale. Here, we describe a pipeline for ADNI rs-fMRI data that encompasses the download of necessary imaging and clinical data, temporally aligning the clinical and imaging data, preprocessing, and quality control. We integrate data curation and preprocessing across all ADNI sites and scanner types using a combination of open-source software (Clinica, fMRIPrep, and MRIQC) and bespoke tools. Quality metrics and repor

In this paper, we look into Signed Product Cordial Labeling for Splitting Graphs of Bull graph and Splitting graph of Star graph , Square of Path graph, Coronaand also for the graph obtained by joining two copies of Helm by a Path of arbitrary length.

This paper describes the final prototype of an assistive robot used for increasing engagement of older adults in the context of SHAPES project. It then highlights lessons learned from hands-on training during the first phases of the pilots at Clinica Humana and Can Granada residence in Mallorca (Spain).

In this paper we present a delay induced model for hepatitis C virus incorporating the healthy and infected hepatocytes as well as infectious and noninfectious virions. The model is mathematically analyzed and characterized, both for the steady states and the dynamical behavior of the model. It is shown that time delay does not affect the local asymptotic stability of the uninfected steady state. However, it can destabilize the endemic equilibrium, leading to Hopf bifurcation to periodic solutions with realistic data sets. The model is also validated using 12 patient data obtained from the study, conducted at the University of Sao Paulo Hospital das clinicas.

Creatine is best known as a muscle-building supplement, but scientists are now investigating whether it could also help treat depression by boosting the brain's energy supply。 A new review examined five randomized clinical trials involving 238 participants and found mixed results。 Two studies, both involving women with major depressive disorder, re

Researchers have shown that ultracold atoms can be driven into a strange new quantum state called a fractional Fermi sea, where particles organize themselves in unexpected ways。 The discovery points to a new phase of matter that goes beyond established quantum theories and could expand the possibilities of quantum simulation

A colossal ancient collision may have left some of the Moon’s deepest secrets surprisingly close to future Artemis landing sites。 By recreating the impact that formed the giant South Pole-Aitken basin—the Moon’s largest and oldest crater—scientists found that a low-angle strike from a large, iron-cored object blasted material from deep inside the M

A new nature-inspired membrane uses perfectly uniform one-nanometer pores to filter molecules with remarkable precision。 The technology could transform industries such as pharmaceuticals and textiles by reducing energy consumption, improving water reuse, and delivering separation performance far beyond current filters

Peptide drugs are popular, but FDA scientists warn they're untested, may be harmful

Ron DeSantis calls it a crackdown on "radical climate policies

A distant galaxy nicknamed Shadow Blaster may have revealed a surprising source of cosmic neutrinos: extreme star formation instead of a supermassive black hole。 The discovery suggests that hidden, dust-filled starburst galaxies could account for a significant fraction of the Universe’s high-energy neutrinos

Oxford physicists have created an entirely new type of Schrödinger’s cat-like quantum state using components that are themselves highly quantum in nature。 The advance could open new possibilities for more resilient quantum computers and deeper insights into the strange rules that govern the quantum universe

Operation by two Russia-state groups has been ongoing since at least March

Researchers discovered that hydrogen radicals generated by intense UV light can break down stubborn PFAS “forever chemicals” without added chemicals。 The breakthrough reveals a key mechanism that could lead to greener and more effective technologies for permanently destroying these pollutants

Also, the science of poop's distinctive shape, boron buckyballs, and the secret to a soccer feint

They may not look as good, but Nano Banana 2 Lite images only take a few seconds to create

A new study suggests Earth may have been sending tiny hitchhikers to Venus for billions of years。 Researchers found that asteroid impacts could launch microbes into space, where some might survive the journey and end up suspended in Venus' clouds。 If future missions detect life there, there's a surprising chance it didn't originate on Venus at all—

Using the Keck Observatory, astronomers measured the spins of dozens of giant planets and brown dwarfs orbiting distant stars。 They found that giant planets can spin faster than much more massive brown dwarfs, challenging simple assumptions about mass and rotation。 The results suggest that magnetic fields and formation processes play a major role i

What if some black holes aren’t black holes at all。 A new theoretical study suggests that when a massive star collapses, it might not form a singularity hidden behind an event horizon。 Instead, the collapse could trigger the birth of a tiny new universe inside the dying star