BrainLesion Suite is a versatile toolkit for building modular brain lesion image analysis pipelines in Python. Following Pythonic principles, BrainLesion Suite is designed to provide a 'brainless' development experience, minimizing cognitive effort and streamlining the creation of complex workflows for clinical and scientific practice. At its core is an adaptable preprocessing module that performs co-registration, atlas registration, and optional skull-stripping and defacing on arbitrary multi-modal input images. BrainLesion Suite leverages algorithms from the BraTS challenge to synthesize missing modalities, inpaint lesions, and generate pathology-specific tumor segmentations. BrainLesion Suite also enables quantifying segmentation model performance, with tools such as panoptica to compute lesion-wise metrics. Although BrainLesion Suite was originally developed for image analysis pipelines of brain lesions such as glioma, metastasis, and multiple sclerosis, it can be adapted for other biomedical image analysis applications. The individual BrainLesion Suite packages and tutorials are accessible on GitHub.
Recent endeavors towards directly using large language models (LLMs) as agent models to execute interactive planning tasks have shown commendable results. Despite their achievements, however, they still struggle with brainless trial-and-error in global planning and generating hallucinatory actions in local planning due to their poor understanding of the ``real'' physical world. Imitating humans' mental world knowledge model which provides global prior knowledge before the task and maintains local dynamic knowledge during the task, in this paper, we introduce parametric World Knowledge Model (WKM) to facilitate agent planning. Concretely, we steer the agent model to self-synthesize knowledge from both expert and sampled trajectories. Then we develop WKM, providing prior task knowledge to guide the global planning and dynamic state knowledge to assist the local planning. Experimental results on three complex real-world simulated datasets with three state-of-the-art open-source LLMs, Mistral-7B, Gemma-7B, and Llama-3-8B, demonstrate that our method can achieve superior performance compared to various strong baselines. Besides, we analyze to illustrate that our WKM can effectively alle
Agents based on large language models (LLMs) struggle with brainless trial-and-error and generating hallucinatory actions due to a lack of global planning in long-horizon tasks. In this paper, we introduce a plan-and-execute framework and propose EAGLET, an efficient and effective planner training method to enhance the executor agent's planning abilities without human effort. Specifically, we train a plug-and-play global planner through a two-step process: we first synthesize high-quality plans from an advanced LLM using our proposed homologous consensus filtering strategy, and apply fine-tuning as a cold start. Moreover, we further improve the planner with a rule-based reinforcement learning stage using a novel executor capability gain reward, ensuring it can handle task instructions of varying difficulty. Experiments on three long-horizon agent tasks show that executor agents equipped with our planner outperform existing methods, achieving new state-of-the-art performance. Meanwhile, EAGLET reduces training costs by 8x compared to RL-based baselines, and it does not require manual effort or extra training data, offering an efficient and effective solution.
Active systems of self-propelled agents, e.g., birds, fish, and bacteria, can organize their collective motion into myriad autonomous behaviors. Ubiquitous in nature and across length scales, such phenomena are also amenable to artificial settings, e.g., where brainless self-propelled robots orchestrate their movements into spatio-temportal patterns via the application of external cues or when confined within flexible boundaries. Very much like their natural counterparts, these approaches typically require many units to initiate collective motion such that controlling the ensuing dynamics is challenging. Here, we demonstrate a novel yet simple mechanism that leverages nonlinear elasticity to tame near-diffusive motile particles in forming structures capable of directed motion and other emergent intelligent behaviors. Our elasto-active system comprises two centimeter-sized self-propelled microbots connected with elastic beams. These microbots exert forces that suffice to buckle the beam and set the structure in motion. We first rationalize the physics of the interaction between the beam and the microbots. Then we use reduced order models to predict the interactions of our elasto-act
Mobility is a key factor in urban life and transport network plays a vital role in mobility. Worse transport network having less mobility is one of the key reasons to decline the living standard in any unplanned mega city. Transport mobility enhancement in an unplanned mega city is always challenging due to various constraints including complex design and high cost involvement. The aim of this thesis is to enhance transport mobility in a megacity introducing a bicycle lane. To design the bicycle lane natural Physarum, brainless single celled multi-nucleated protist, is studied and modified for better optimization. Recently Physarum inspired techniques are drawn significant attention to the construction of effective networks. Exiting Physarum inspired models effectively and efficiently solves different problems including transport network design and modification and implication for bicycle lane is the unique contribution of this study. Central area of Dhaka, the capital city of Bangladesh, is considered to analyze and design the bicycle lane network bypassing primary roads.
Yes, it was, in fact, a Unix system
Four nearby white dwarf stars have been discovered hiding in plain sight beside brighter red dwarf companions。 Hubble's ultraviolet observations finally revealed the long-hidden stellar remnants, including one just 25 light-years away that took nearly three decades to confirm。 The findings match long-standing predictions and suggest our corner of t
The hunt for ancient life on Mars just got an important test run。 Scientists confirmed that the Rosalind Franklin rover's sophisticated instrument can detect subtle differences in two stable molecules that could preserve evidence of past life for billions of years。 But the team also uncovered a surprise: organic molecules in the Murchison meteorite
Researchers solved the mystery of how soft lithium dendrites crack the hard ceramic inside solid-state batteries, triggering short circuits。 The breakthrough could help engineers build safer, longer-lasting batteries for smartphones, electric vehicles, and other electronics
Gold may have a secret self-defense system that helps it resist tarnishing。 Researchers discovered that atoms on gold surfaces reorganize themselves into patterns that block oxygen from reacting with the metal, suppressing oxidation by up to a trillion-fold。 Beyond explaining why gold jewelry stays bright for generations, the finding could help sci
Physicists from Heinrich Heine University Düsseldorf (HHU) have examined a fundamental property of quantum mechanics in collaboration with the German Aerospace Center (DLR)。 In the scientific journal Physical Review Letters, they show that this theory does not necessarily need to be formulated with imaginary numbers – real numbers can in fact also
Ultra-fine bubbles may offer a cleaner way to perfect inkjet printing for next-generation electronics。 By simply changing the number of bubbles in each droplet, researchers were able to dramatically reshape the final printed pattern without leaving behind unwanted chemical residues
Scientists have identified new clues that could help astronomers spot one of the most famous hypothetical alien megastructures: a Dyson sphere。 The study finds that red dwarfs and white dwarfs are the most promising stars to examine, since advanced civilizations could potentially build energy-harvesting swarms around them more easily。 These objects
Scientists at Nanyang Technological University in Singapore have discovered a surprisingly simple way to create exotic light structures called optical skyrmions using a 200-year-old optical effect known as the Poisson spot。 Instead of relying on expensive, highly engineered materials, they simply shine a laser at a tiny circular disc, producing sta