Granzyme B (GraB) induces apoptosis in the presence of perforin. Perforin polymerizes in the cell membrane to form a nonspecific ion pore, but it is not known where GraB acts to initiate the events that ultimately lead to apoptosis. It has been hypothesized that GraB enters the target cell through a perforin channel and then initiates apoptosis by cleaving and activating members of the ICE/Ced-3 family of cell death proteases. To determine if GraB can enter the cell, we treated YAC-1 or HeLa cells with FITC-labeled GraB and measured intracellular fluorescence with a high sensitivity CCD camera and image analyzer. GraB was internalized and found diffusely dispersed in the cell cytoplasm within 10 min. Uptake was inhibited at low temperature (4 degrees C) and by pretreatment with metabolic inhibitors, NaF and DNP, or cytochalasin B, a drug that both blocks microfilament formation, and FITC-GraB remained on the cell membrane localized in patches. With the simultaneous addition of perforin and FITC-GraB, no significant increase in cytoplasmic fluorescence was observed over that found in cells treated only with FITC-GraB. However, FITC-GraB was now detected in the nucleus of apoptotic cells labeling apoptotic bodies and localized areas within and along the nuclear membrane. The ability of GraB to enter cells in the absence of perforin was reexamined using anti-GraB antibody immunogold staining of ultrathin cryosections of cells incubated with GraB. Within 15 min, gold particles were detected both on the plasma membrane and in the cytoplasm of cells with some gold staining adjacent to the nuclear envelope but not in the nucleus. Cells internalizing GraB in the absence of perforin appeared morphologically normal by Hoechst staining and electron microscopy. GraB directly microinjected into the cytoplasm of B16 melanoma cells induced transient plasma membrane blebbing and nuclear coarsening but the cells did not become frankly apoptotic unless perforin was added. We conclude that GraB can enter cells autonomously but that perforin initiates the apoptotic process and the entry of GraB into the nucleus.
Discussions of land grabs for various purposes, including environmental ends, have expanded in recent years, yet land grabbing remains inconsistently defined and poorly understood. Our ability to assess the extent to which land grabs are occurring, and to identify the mixture of factors driving land and resource acquisition, is limited. This paper assesses whether a land grab for conservation is happening in southern Chile, and identifies the various driving forces that combine to drive land acquisitions in the region, based on a detailed exploration of the recent massive growth in privately owned protected areas in the region. This paper finds that the various dominant definitions of land grabs each apply only partially to southern Chile, that land grabs for conservation need to be understood as the latest stage in a longer process by which the region's natural resources are incorporated into the Chilean and the global economy, and that green grabs interact in various ways with broader resource grabs, particularly for forestry and hydroelectricity. This case study demonstrates the limitations of some definitions of land grabs, particularly their focus on capitalist accumulation within land grabs, their international nature and their emphasis on legal processes.
Societal pressure on the global land and freshwater resources is increasing as a result of the rising food demand by the growing human population, dietary changes, and the enhancement of biofuel production induced by the rising oil prices and recent changes in United States and European Union bioethanol policies. Many countries and corporations have started to acquire relatively inexpensive and productive agricultural land located in foreign countries, as evidenced by the dramatic increase in the number of transnational land deals between 2005 and 2009. Often known as "land grabbing," this phenomenon is associated with an appropriation of freshwater resources that has never been assessed before. Here we gather land-grabbing data from multiple sources and use a hydrological model to determine the associated rates of freshwater grabbing. We find that land and water grabbing are occurring at alarming rates in all continents except Antarctica. The per capita volume of grabbed water often exceeds the water requirements for a balanced diet and would be sufficient to improve food security and abate malnourishment in the grabbed countries. It is found that about 0.31 × 10(12) m(3) · y(-1) of green water (i.e., rainwater) and up to 0.14 × 10(12) m(3) · y(-1) of blue water (i.e., irrigation water) are appropriated globally for crop and livestock production in 47 × 10(6) ha of grabbed land worldwide (i.e., in 90% of the reported global grabbed land).
Land grabbing has emerged as a significant issue in contemporary global governance that cuts across the fields of development, investment, food security, among others. Whereas land grabbing per se is not a new phenomenon, having historical precedents in the eras of imperialism, the character, scale, pace, orientation and key drivers of the recent wave of land grabs is a distinct historical phenomenon closely tied to major shifts in power and production in the global political economy. Land grabbing is facilitated by ever greater flows of capital, goods, and ideas across borders, and these flows occur through axes of power that are far more polycentric than the North-South imperialist tradition. In this introduction we argue that land grabbing speaks to many of the core questions of globalization studies. However, we note scholars of globalization have yet to deeply engage with this new field. We situate land grabbing in an era of advanced capitalism, multiple global crises and the role of new configurations of power and resistance in global governance institutions. The essays in this collection contribute to identifying land grabbing as an important and urgent topic for theoretical and empirical investigations to deepen our understanding of contemporary globalization and governance.
We introduce this special issue by explaining seven characteristics of land grabbing in Latin America. These features are not unique to the region. By highlighting them – arguing, for instance, that a key aspect in Latin America is intra-regional land grabbing driven by (trans)Latina companies – we hope to inspire new cross-regional comparisons to understand the dynamics of “global” land grabbing. Our focus on Latin America challenges some problematic generalisations in the literature, for instance, that land grabs occur mainly in fragile states. We interrogate the relationship between land grabbing and the “foreignisation” narrative, and the need to revisit the broader question of land concentration. Thus we build upon the literature locating land grabs and the land question within the political economy of global capitalism. Cette introduction au numéro spécial présente sept caractéristiques de l'accaparement des terres en Amérique latine, caractéristiques qui ne sont pas propres à la région. En les mettant en lumière, notamment en soutenant qu'en Amérique latine le phénomène, impulsé par des compagnies latino-américaine, est avant tout intra-régional, nous espérons susciter de nouvelles comparaisons inter-régionales afin de mieux comprendre les dynamiques mondiales de l'accaparement de terres. L'accent mis sur Amérique latine permet de remettre en question des généralisations auxquelles s'adonnent de nombreux écrits, comme par exemple que l'accaparement se produit principalement dans les états fragiles. Nous examinons les liens établis entre l'accaparement de terres et la main mise étrangère pour montrer la nécessité de réévaluer la question élargie de la concentration de terres. Les articles du numéro situent l'accaparement des terres dans le cadre de l’économie politique du capitalisme mondial.
The term “ocean grabbing” has been used to describe actions, policies or initiatives that deprive small-scale fishers of resources, dispossess vulnerable populations of coastal lands, and/or undermine historical access to areas of the sea. Rights and access to marine resources and spaces are frequently reallocated through government or private sector initiatives to achieve conservation, management or development objectives with a variety of outcomes for different sectors of society. This paper provides a definition and gives examples of reallocations of marine resources or spaces that might constitute “ocean grabbing”. It offers a tentative framework for evaluating whether marine conservation, management or development is ocean grabbing and proposes an agenda for future research. For a reallocation to be considered ocean grabbing, it must: (1) occur by means of inadequate governance, and (2) be implemented using actions that undermine human security and livelihoods, or (3) produce impacts that reduce social–ecological well-being. Future research on ocean grabbing will: document case studies, drivers and consequences; conduct spatial and historical analyses; and investigate solutions. The intent is to stimulate rigorous discussion and promote systematic inquiry into the phenomenon of ocean grabbing.
Across the world, ‘green grabbing’ – the appropriation of land and resources for environmental ends – is an emerging process of deep and growing significance. The vigorous debate on ‘land grabbing’ already highlights instances where ‘green’ credentials are called upon to justify appropriations of land for food or fuel – as where large tracts of land are acquired not just for ‘more efficient farming’ or ‘food security’, but also to ‘alleviate pressure on forests’. In other cases, however, environmental green agendas are the core drivers and goals of grabs – whether linked to biodiversity conservation, biocarbon sequestration, biofuels, ecosystem services, ecotourism or ‘offsets’ related to any and all of these. In some cases these involve the wholesale alienation of land, and in others the restructuring of rules and authority in the access, use and management of resources that may have profoundly alienating effects. Green grabbing builds on well-known histories of colonial and neo-colonial resource alienation in the name of the environment – whether for parks, forest reserves or to halt assumed destructive local practices. Yet it involves novel forms of valuation, commodification and markets for pieces and aspects of nature, and an extraordinary new range of actors and alliances – as pension funds and venture capitalists, commodity traders and consultants, GIS service providers and business entrepreneurs, ecotourism companies and the military, green activists and anxious consumers among others find once-unlikely common interests. This collection draws new theorisation together with cases from African, Asian and Latin American settings, and links critical studies of nature with critical agrarian studies, to ask: To what extent and in what ways do ‘green grabs’ constitute new forms of appropriation of nature? How and when do circulations of green capital become manifest in actual appropriations on the ground – through what political and discursive dynamics? What are the implications for ecologies, landscapes and livelihoods? And who is gaining and who is losing – how are agrarian social relations, rights and authority being restructured, and in whose interests?
The unprecedented increase in the world population coupled with the great demand for food have encouraged several investors to acquire land and water in some developing countries, Sudan is not an exception. This current phenomenon often referred to as “land grabbing” as it always violates the right of local land users and affects the environment. This paper aims to highlight the process by which local and foreign investors acquire communal lands in Sudan and to underline its implication on pastoral livelihood. The paper is mainly based on desk review and deep analysis of some recent documents. The paper has come out with the fact that under the pretext of development and food security, huge communal lands were taken from local producers and leased “soled” to the investors (grabbers). To facilitate land grabbing, the government of Sudan has frequently been embarked on amending land tenure system several times. The Unregistered Land Act of 1971, Ministerial Act of 1996 and the Investment Act of 2013, have paved the way for more land grabbing in Sudan. These acts ignored completely the historical right of the local communities over land resources. Lacks of transparency, unfair compensation and limited or absent consultation of the local communities are some characteristics shaping land grabbing in Sudan. Land for local producers is the main asset and a source of everything (livelihood) thus, denying such right means lacking everything. This explains why food insecurity, spread of poverty, disputes and conflict are now widely dominated most of pastoral areas. The paper aims to contribute to the ongoing debate on land grabbing and open windows for more research in such hot issue. It provides planners with some ideas that might help in formulating sound policy regarding land acquisition. Like any African country, the government of Sudan has to find rational way to make the investment a win win deal if it is really looking for food security, social peace and sustainable development.
The current global land grab is causing radical changes in the use and ownership of land. The main process driving the land grab, or ‘foreignisation of space’, as highlighted in the media and the emerging literature is the production of food and biofuel for export in the aftermath of recent food and energy crises. However, there are several other processes driving the land rush. In this article I argue that an analytical framework that focuses on only one or two processes that drive the global land grab offers a narrow perspective on this complex process. It will be unable to take into account the full range and extent of agrarian and social changes that occur in light of the land grab and their strategic implications for poor people's livelihoods. An important starting point is to identify the broad processes driving the current land rush, and trace their structural and institutional origins. To do so, I identify and examine seven factors that are giving rise to radical changes in landownership and land use in Africa, Asia and Latin America. Finally, ‘codes of conduct’ as proposed by several quarters in the context of global land grab are unlikely to work in favour of the poor.
The contestation and appropriation of water is not new, but it has been highlighted by recent global debates on land grabbing. Water grabbing takes place in a field that is locally and globally plural-legal. Formal law has been fostering both land and water grabs but formal water and land management have been separated from each other—an institutional void that makes encroachment even easier. Ambiguous processes of global water and land governance have increased local-level uncertainties and complexities that powerful players can navigate, making them into mechanisms of exclusion of poor and marginalised people. As in formal land management corporate influence has grown. For less powerful players resolving ambiguities in conflicting regulatory frameworks may require tipping the balance towards the most congenial. Yet, compared with land governance, global water governance is less contested from an equity and water justice perspective, even though land is fixed, while water is fluid and part of the hydrological cycle; therefore water grabbing potentially affects greater numbers of diverse water users. Water grabbing can be a powerful entry point for the contestation needed to build counterweights to the neoliberal, corporate business-led convergence in global resource governance discourses and processes. Elaborating a human right to water in response to water grabbing is urgently needed.
Scholars, practitioners and activists generally agree that investor interest in land has climbed sharply, although they differ about what to call this phenomenon and how to analyse it. This introduction discusses several contested definitional, conceptual, methodological and political issues in the land grab debate. The initial ‘making sense’ period drew sweeping conclusions from large databases, rapid-appraisal fieldwork and local case studies. Today research examines financialisation of land, ‘water grabbing’, ‘green grabbing’ and grabbing for industrial and urbanisation projects, and a substantial literature challenges key assumptions of the early discussion (the emphasis on foreign actors in Africa and on food and biofuels production, the claim that local populations are inevitably displaced or negatively affected). The authors in this collection, representing a diversity of approaches and backgrounds, argue the need to move beyond the basic questions of the ‘making sense’ period of the debate and share a common commitment to connecting analyses of contemporary land grabbing to its historical antecedents and legal contexts and to longstanding agrarian political economy questions concerning forms of dispossession and accumulation, the role of labour and the impediments to the development of capitalism in agriculture. They call for more rigorous grounding of claims about impacts, for scrutiny of failed projects and for (re)examination of the longue durée, social differentiation, the agency of contending social classes and forms of grassroots resistance as key elements shaping agrarian outcomes.
Recent large-scale land acquisitions for agricultural production (including biofuels), popularly known as 'land grabbing', have attracted headline attention. Water as both a target and driver of this phenomenon has been largely ignored despite the interconnectedness of water and land. This special issue aims to fill this gap and to widen and deepen the lens beyond the confines of the literature’s still limited focus on agriculture-driven resource grabbing. The articles in this collection demonstrate that the fluid nature of water and its hydrologic complexity often obscure how water grabbing takes place and what the associated impacts on the environment and diverse social groups are. The fluid properties of water interact with the 'slippery' nature of the grabbing processes: unequal power relations; fuzziness between legality and illegality and formal and informal rights; unclear administrative boundaries and jurisdictions, and fragmented negotiation processes. All these factors combined with the powerful material, discursive and symbolic characteristics of water make 'water grabbing' a site for conflict with potential drastic impacts on the current and future uses and benefits of water, rights as well as changes in tenure relations.
Recent research on land deals reports gigantic quantities of hectares seized, with relatively little regard for the solidity of the evidence or for considerations of scale other than area. This commentary questions the usefulness of aggregating data of uneven quality and transforming it into ‘facts’. Making claims on the basis of problematic evidence does not serve agrarian and human rights activists well, since it may undercut their legitimacy and make it difficult for them to identify their adversaries. Studying land tenure and corporate ownership is inherently complicated, with intractable legibility problems. Social scientists must subject their sources to critical scrutiny and understand the contexts of their production, preservation and dissemination. An accelerated process of dispossession is clearly in motion, but countering it effectively requires precise and accurate data, which are difficult to obtain. Oversimplified claims may not only undermine efforts to counter specific cases of land grabbing – and claims about land grabbing more generally – but may also divert attention from less publicized cases and from the actors behind the land grabbing. They also tend to reduce land grabbing to a quantitative problem rather than focusing on the social relations that it may or may not transform.This is a much revised and expanded version of a paper presented at the Plenary Session Roundtable on Methodologies: Identifying, Counting and Understanding, International Academic Conference on Global Land Grabbing II, organized by the Land Deals Politics Initiative (LDPI), Cornell University, 17–19 October 2012. I am grateful to Jun Borras, Andrés León, Carlos Oya, Katherine Verdery and this journal's reviewers for comments that contributed to sharpening an earlier draft.
Land grabbing has gained momentum in Latin America and the Caribbean during the past decade. The phenomenon has taken different forms and character as compared to processes that occur in other regions of the world, especially Africa. It puts into question some of the assumptions in the emerging literature on land grabbing, suggesting these are too food-centered/too food crisis-centered, too land-centred, too centred on new global food regime players – China, South Korea, Gulf States and India – and too centred on Africa. There are four key mechanisms through which land grabbing in Latin American and the Caribbean has been carried out: food security initiatives, energy/fuel security ventures, other climate change mitigation strategies, and recent demands for resources from newer hubs of global capital. The hallmark of land grabbing in the region is its intra-regional character: the key investors are (Trans-)Latin American companies, often in alliance with international capital and the central state. Initial evidence suggests that recent land investments have consolidated the earlier trend away from (re)distributive land policies in most countries in the region, and are likely to result in widespread reconcentration of land and capital.
Political reactions ‘from below’ to global land grabbing have been vastly more varied and complex than is usually assumed. This essay introduces a collection of groundbreaking studies that discuss responses that range from various types of organized and everyday resistance to demands for incorporation or for better terms of incorporation into land deals. Initiatives ‘from below’ in response to land deals have involved local and transnational alliances and the use of legal and extra-legal methods, and have brought victories and defeats. The relevance of political reactions to land grabbing is discussed in light of theories of social movements and critical agrarian studies. Future research on reactions ‘from below’ to land grabbing must include greater attention to gender and generational differences in both impacts and political agency. Keywords: dispossession; land grabbing; large-scale land acquisitions; land tenure; peasants; resistance; contentious politics; agrarian change
Critical scholars have made extensive use of the concepts of primitive accumulation and accumulation by dispossession to analyse the global land grab. These concepts have been crucial to efforts to understand the land grab in terms of the creation, expansion and reproduction of capitalist social relations, of accumulation by extra-economic means, and of dispossessory responses to capitalist crises. This paper provides an overview of these approaches. It also argues that there are substantial challenges involved in the use of primitive accumulation and accumulation by dispossession, including tensions and ambiguities over what the concepts mean, the assumptions embedded within them and problems of fit with other conceptualisations of the land grab. The paper also highlights resources for engaging with these challenges in the land grab literature.
Ungrounded haptic devices for virtual reality (VR) applications lack the ability to convincingly render the sensations of a grasped virtual object's rigidity and weight. We present Grabity, a wearable haptic device designed to simulate kinesthetic pad opposition grip forces and weight for grasping virtual objects in VR. The device is mounted on the index finger and thumb and enables precision grasps with a wide range of motion. A unidirectional brake creates rigid grasping force feedback. Two voice coil actuators create virtual force tangential to each finger pad through asymmetric skin deformation. These forces can be perceived as gravitational and inertial forces of virtual objects. The rotational orientation of the voice coil actuators is passively aligned with the real direction of gravity through a revolute joint, causing the virtual forces to always point downward. This paper evaluates the performance of Grabity through two user studies, finding promising ability to simulate different levels of weight with convincing object rigidity. The first user study shows that Grabity can convey various magnitudes of weight and force sensations to users by manipulating the amplitude of the asymmetric vibration. The second user study shows that users can differentiate different weights in a virtual environment using Grabity.
Large-scale acquisitions of agricultural land in developing countries have been rapidly increasing in the last 10 years, contributing to a major agrarian transition from subsistence or small scale farming to large-scale commercial agriculture by agribusiness transnational corporations. Likely driven by recent food crises, new bioenergy policies, and financial speculations, this phenomenon has been often investigated from the economic development, human right, land tenure and food security perspectives, while its hydrologic implications have remained understudied. It has been suggested that a major driver of large-scale land acquisitions (LSLAs) is the quest for water resources that can be used (locally) to sustain agricultural production in the acquired land. The appropriation of water resources associated with LSLAs has often been termed ‘water grabbing’, though to date a formal definition of such a normative and inherently pejorative term is missing. The intrinsic assumption is that the acquisition of water undergoes the same dynamics of unbalanced power relationships that underlie many LSLAs. Here we invoke hydrological theories of “green” and “blue” water flows to stress the extent to which water appropriations are inherently coupled to land acquisitions and specifically focus on blue water. We then propose a formal definition of blue water grabbing based both on biophysical conditions (water scarcity) and ethical implications (human right to food). Blue water grabs are appropriations of irrigation (i.e., blue) water in regions affected by undernourishment and where agricultural production is constrained by blue water availability. We use this framework to provide a global assessment of the likelihood that LSLAs entail blue water grabbing.
In many countries, public sector institutions impose heavy burdens on economic life: heavy and arbitrary taxes retard investment, regulations enrich corrupt bureaucrats, state firms consume national wealth, and the most talented people turn to rent-seeking rather than productive activities. As a consequence of such predatory policies--described in this book as the grabbing hand of the state--entrepreneurship lingers and economies stagnate. The authors of this collection of essays describe many of these pathologies of a grabbing hand government, and examine their consequences for growth. The essays share a common viewpoint that political control of economic life is central to the many government failures that we observe. Fortunately, a correct diagnosis suggests the cures, including the best strategies of fighting corruption, privatization of state firms, and institutional building in the former socialist economies. Depoliticization of economic life emerges as the crucial theme of the appropriate reforms. The book describes the experiences with the grabbing hand government and its reform in medieval Europe, developing countries, transition economies, as well as today's United States.