The premiere issue of the Japanese Journal of Thoracic Surgery, known as "Kyobu Geka" in Japanese with English abstract, was launched in 1948. Articles of the journal become obtainable by PubMed in 1961 (volume 14). In the present study, the journal was evaluated using science database, Scopus and PubMed. Jpn J Thorac Cardiovasc Surg and Gen Thorac Cardiovasc Surg were used for comparison. A total of 7,490 articles published in "Kyobu Geka" by December 2008 were searched. Of these, 1,573 articles (21.0%) were cited for a total of 2,548 times. Articles cited by non-Japanese papers were mostly of rare case reports and experience of use of newly introduced devices. The authors' names and source titles of cited articles can be searched easily, and the information obtained is valuable for research, writing research grant applications and academic articles. In conclusion, although "Kyobu Geka" is published in Japanese, it has been cited by many international journals in many languages and, therefore, is making a fine performance.
Geçmişte olduğu gibi günümüzde de kurum ve kuruluşların içinde bulundukları koşullara uyum sağlanarak başarıyı yakalamaları için çeşitli stratejiler ve planlamalar yapmaları gerekmektedir. Bu bağlamda gerekli stratejiler geliştirmek ve çeşitli planlamalar yapmak kurumlar açısından önem kazanmaktadır. Bu kurumlardan biri Bölgesel Kalkınma Ajanslarıdır. Çalışmanın amacı, TRC3 bölgesinde kurulan Dicle Kalkınma Ajansı (DİKA) ile TR32 bölgesinde kurulan Güney Ege Kalkınma Ajansı (GEKA) stratejik planlama türlerinden SWOT analizlerini değerlendirmektir. Çalışma, biri doğuda diğeri batıda olmak üzere kuruluş tarihleri birbirine yakın olan iki kalkınma ajansın profilini belirleyerek bu konuda literatüre katkı sunmak açısından önem kazanmaktadır. Çalışmada, betimsel araştırma yöntemi kullanılmıştır. Çalışma sonucunda DİKA ile GEKA’nın sorumlu oldukları bölgelerde altyapı, üstyapı, üretim, istihdam ve ihracat gibi çeşitli alanlarda önemli katkılarda bulunduğunu göstermektedir. Ayrıca bölgesel verilerin üretilmesi, bölgesel planların geliştirilmesi, stratejik alanlar ve sektörler hakkında raporların hazırlanması ve yerel yönetimler ile kurumlar için hizmet içi eğitim ve kurumsallaşma desteğinin sağlanması yönünde katkılar sağladıkları görülmüştür. GEKA, sektörlerin gelişiminde, yeni yatırım alanların oluşmasında, mevcut yatırımların gelişmesinde ve bölge ile ilgili veri üretmede etkili olabilmiştir. Ancak DİKA’nın farklı sektörlerde olmak üzere yatırım potansiyelinin artmasında, yeni yatırımların gelişmesinde ve bölgenin sosyo-ekonomik göstergelerin düzeyinin artmasına olan etkisi sınırlı kalmıştır.
). Subsequent reports of immediate and delayed skin reactions emerged. This study presents a case of a 64-year-old male who developed multiple keratoacanthomas approximately two weeks after receiving a second booster dose of the Pfizer vaccine. The patient, who had significant medical history of hypertension and diabetes, presented with erythematous, crateriform lesions on his limbs. A physical examination and histopathological analysis confirmed the diagnosis of Generalized Eruptive Keratoacanthoma (GEKA). Treatment involved cemiplimab I.v. 350 mg administered every three weeks. Within two months, the patient showed significant improvement, with the disappearance of all lesions. Dermoscopy and histopathological exams supported the GEKA diagnosis, which is a rare variant of multiple keratoacanthomas. This case suggests a potential immune-mediated mechanism triggered by the COVID-19 vaccine, leading to the rapid development of keratoacanthomas. Treatment with cemiplimab showed promise, highlighting the potential of immune checkpoint inhibitors in managing multiple keratoacanthomas. Further research is needed to explore the efficacy and safety of such treatments.
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Dutch sealing solution specialist Lagersmit and pump supplier Vos Gekas & Boot (VGB) have signed a strategic partnership contract.
Turizm sektörü için ülkelerin tanıtımları ve kalkınmalarında kullanılan en önemli araçlardan birisi olduğu söylenebilir. Dolayısıyla ülkelerin yönetiminde bulunan hükümetlerin ulusal bir turizm politikası ya da stratejisi olması gerekir. Ülkemiz açısından konuya baktığımızda, 2000’li yıllara gelinceye kadar turizmin ulusal politikalarla geliştirilmeye çalışıldığı görülmektedir. Bununla birlikte, AB’ye uyum süreciyle birlikte yerelleşme eğilimlerinin artmasıyla kalkınma anlayışlarındaki değişimin turizm stratejisine de yansıdığı söylenebilir. Bu bağlamda ülkemizde 2006 yılında 5449 sayılı kanunla Kalkınma Ajanslarının kurulmaya başlamasıyla kalkınma politikalarında ve yönetiminde ulusal kalkınma politikaları ile uyumlu bölgesel kalkınmaya da geçildiği bilinmektedir. Bu çalışmada, öncelikle ulusal turizm stratejilerine gerek kalkınma planlarında, gerekse Kültür ve Turizm Bakanlığının hazırladığı planlarda nasıl yer verildiği incelenecek, arkasından Türkiye’nin önemli bir turizm bölgesi olan GEKA (Güney Ege Kalkınma Ajansı-Muğla,Aydın ve Denizli)’da kalkınma açısından turizme ne derece yer verildiği irdelenecektir. Sonuç bölümünde ise bu politikaların karşılaştırmalı bir değerlendirmesi yapılacaktır.
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À l’instar de l’historien Jacques Proust, grand spécialiste du siècle des lumières, qui s’était tourné vers le Japon au terme de sa carrière et nous a laissé une magnifique réflexion sur la manière dont les savoirs occidentaux ont trouvé leur chemin au Japon, l’ancien directeur de recherches du laboratoire de chimie des substances naturelles du CNRS Gabor Lukacs poursuit depuis sept ans une recherche assidue et fructueuse sur les ouvrages qui ont joué un rôle important dans la diffusion des s...
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In 1656, at the request of the imperial commissioner Inoue Masashige Chikugo-no-kami, the neo-Confucian physician Mukai Genshō compiled medical instructions given to him by the Dejima trading-post surgeon Hans Juriaen Hancke. This was the first text on Western surgery by a trained Japanese specialist. Based on an extensive analysis of related Japanese source material, it is shown that the manuscript Komōryū geka hiyō ("Secret compendium of red-head-style external medicine"), previously considered to represent Mukai's original report, is a rather corrupted version. Other manuscripts, such as Oranda-den geka ruihō ("Arranged formulas of Dutch external medicine"), Oranda geka ihō ("Medical formulas of Dutch external medicine"), or Shōji shinan ("Compass of diagnosis and treatment"), are much more coherent in their contents and fit well with Dutch sources. Furthermore, it is shown how Mukai "identified" and "translated" the Latin names of ulcers, tumours, inflammations, etc., by comparing Hancke's teachings with the most comprehensive Eastern source on surgical matters, the Waìke zhèngzōng (Jap. Geka seisō, "Orthodox manual of external medicine"). His eclectic approach resulted in a combination of Sino-Japanese pathology with Western treatment methods. Mukai had set an example that would dominate the reception of Western medicine in Japan for more than a century. It became widely known as early as 1670, when Yamawaki Dōen included many parts of Mukai's report in his Oranda geka ryōhō ("Good formulas of Dutch external medicine"), the first Japanese book on red-head-style external surgery.
We present the design and evaluation of Graphically Enhanced Keyboard Accelerators (GEKA), a user interface interaction method allowing commands within a graphical application to be quickly and easily invoked through the keyboard. The high-level goal of this work is to make interactive desktop computing more pleasant and productive for experienced computer users. GEKA is designed to provide complete coverage of the command set, to require low visual demand, and to support ease of learning and remembering, a low error rate, and high speed. This thesis describes GEKA's design and two related user studies. A formative study with 10 participants explored how our target users currently work with Window, Icon, Menu and Pointer (WIMP) interfaces. The results of the study suggest that advanced computer users prefer to execute commands with the keyboard. However, they are often unable to do so in current applications because shortcuts are not available for all commands or are unknown. This indicates a desire among advanced users for a GEKA-like interaction method and motivates our research. GEKA’s design blends elements from WIMP and command line interfaces, allowing commands to be entered quickly and precisely while shifting the focus of the interaction to recognition rather than recall. GEKA has three key improvements over existing text command systems with graphical feedback: support for multiple parameters in arbitrary order, smarter matching – including abbreviations for all commands, and clear visual feedback of the input characters to facilitate learning and re-use. A laboratory experiment with 12 participants compared GEKA to WIMP interaction methods. We found error rates to be nearly identical and speed to be very competitive. The experiment also explored users’ preferences: When given a choice in situ between WIMP and GEKA for actual command execution, participants overwhelmingly used existing keyboard shortcuts when they knew them and used GEKA when they didn’t. In a questionnaire, each type of GEKA command was rated better than its WIMP equivalent except for zero-parameter GEKA commands relative to keyboard shortcuts. These results suggest that our target user population has a strong preference for GEKA interaction over the mouse-based WIMP methods.
No AccessJournal of Urology1 Jun 1959Primary Retroperitoneal Tumors David B. Scanlan David B. ScanlanDavid B. Scanlan More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)66103-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1959 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited by Lenin A and Govindan K (2020) Primary Retroperitoneal Cystic Neoplasm- Case ReportJournal of Evolution of Medical and Dental Sciences, 10.14260/jemds/2020/320, VOL. 9, NO. 17, (1467-1470), Online publication date: 27-Apr-2020. 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INTRODUCTION: Keratoacanthomas (KA) are common cutaneous skin tumors originating from the hair follicles. Unlike squamous cell carcinoma, KA can regress spontaneously and have a benign evolution. Solitary KA is the most common form but familial multiple KA (Ferguson-Smith type), genetically predisposed KA (such as in xeroderma pigmentosum, or Muir-Torre syndrome), or sporadic multiple eruptive KA (Grzybowski type) have been described. Generalized eruptive KA of Grzybowski (GEKA) is a rare condition (around 40 reported cases). The pathophysiology is still unclear. Human papillomavirus (HPV) has been detected in sporadic KA but the presence of HPV39 has never been reported, to our knowledge, in GEKA. CASE REPORT: GEKA in an 80-year-old woman was successfully treated with acitretin (0.5 mg/kg/day) combined with surgical removal of the largest lesions. Treatment was well tolerated and led to decreased pruritus and tumor regression within 6 months. The presence of HPV39 was detected in a lesion by polymerase chain reaction and Sanger sequencing. No genetic alteration was found, in particular in the genes usually altered in squamous cell carcinoma (including NOTCH1, NOTCH2, CDKN2A, TP53). CONCLUSION: We report a case of GEKA associated with the presence of HPV39 and the successful use of acitretin combined with surgical removal of the larger lesions.
BACKGROUND: Generalized eruptive keratoacanthoma (GEKA) is an extremely rare variant of keratoacanthoma that poses significant diagnostic and therapeutic challenges. PATIENTS: The study included three patients presenting with highly pruritic, generalized eruption of numerous small skin and flesh-colored follicular papules. They were mainly distributed on the face, neck, and trunk. Few larger nodules were also present. Mask-like facies, mucosal involvement, and ectropion were evident in two patients. Family history was irrelevant, and general examination was unremarkable. RESULTS: Histopathological examination revealed typical features of keratoacanthoma, particularly in the larger lesions. Routine laboratory tests were normal, and ultrasonography and computed tomography revealed no evidence of malignancy. Based on the clinicopathological correlation, the diagnosis of our cases was GEKA of Grzybowski. Acitretin 1 mg/kg per day and methotrexate 15 mg/week for three months were associated with mild or no response. Cyclophosphamide pulse therapy 1 g/month for six months was associated with complete clearance of the lesions in the first two patients, while the third was lost to follow-up after failure of acitretin therapy. CONCLUSION: Because of the extreme rarity of reported cases, the common absence of classic large lesions of keratoacanthoma, the atypical histological presentations in some cases, and absence of a uniformly effective therapeutic approach, we believe that GEKA still represents a diagnostic and therapeutic challenge. Cyclophosphamide pulse therapy is a promising alternative to oral retinoids.
VISION Food Engineering for the 21st Century, D. B. Lund Trends in Food Engineering, G. Trystram and J.J. Bimbenet Challenges for the Process Specialist in the 21st Century, K.R. Swartzel Sustainability of Food Sector Development in Tropical Areas, A.L. Raoult-Wack and N. Bricas International Congress on Engineering and Food: The First 25 Years, R. Jowitt PHYSICAL CHEMISTRY State Transitions and Reaction Rates in Concentrated Food Systems, Y. H. Roos and S. M. Lievonen Biopolymer-Biopolymer Interactions at Interfaces and their Impact on Food Colloid Stability, S. Damodaran Triacylglyceride Crystallization in Vegetable Oils, J. F. Toro-Vazquez, E. Dibildox-Alvarado, V. Herrera-Coronado and M. Charo-Alonso The Functionality of Milkfat Fractions in Confectionery and Plastic Fats, A. G. Marangoni Stabilization Mechanisms for Anthocyanin: The Case for Copolymerization Reactions, P. Wesche-Ebeling and A. Argaiz-Jamet MASS TRANSFER Transport Properties in Food Engineering, G. D. Saravacos Mass Transfer and Related Phenomena in Plant Tissue during Heat Treatment and Osmotic Stress, W. Spiess, D. Behsnilian, M. Ferrando, M. Gaiser, U. Gartner, M. Hasch, E. Mayer-Miebach, A. Rathjen, and E. Walz Non-Fickian of Mass Transfer in Fruit Tissue, V. Gekas, F. Oliveira, and G. Crapiste The Cellular Approach in Modeling Mass Transfer in Fruit Tissues, M. Le Maguer, G. Mazzanti, and C. Fernandez Mass Transport and Deformation Relaxation Phenomena in Plant Tissues, P. Fito, A. Chiralt, J. M. Barat and J. Martinez-Monzo The Relation Between Sublimation Rate and Volatile Retention during the Freeze-Drying of Coffee, K. Niranjan, J. M. Pardo, and D. S. Mottram A Proposal of Analysis of the Drying Phenomena by Means of the Fractal Theory, G. F. Gutierrez-Lopez, J. Chanona-Perez, L. Alamilla-Beltran, A. Hernandez-Parada, A. Jimenez-Aparicio, R. Farrera-Rebollo, and C. Odorica-Vargas FOOD RHEOLOGY Relationship Between Rheology and Food Texture, M. C. Bourne Relevance of Rheological Properties in Food Process Engineering, J. Velez-Ruiz Rheological Properties of Concentrated Suspensions: Applications to Foodstuffs, P. J. Carreau, F. Cotton, G. P. Citerne, and M. Moan Mixing of Viscoelastic Fluids: A New Strategy to Elucidate the Influence of Elasticity on Power Consumption, E. Brito-De la Fuente, F. Bertrand, P. Carreau, and P.A. Tanguy Microstructuring of Multiphase Food Systems in Shear and Elongational Process Flows, E. J. Windhab, P. Fischer, M. Stranzinger, and S. Kaufmann Modeling Viscosity of Starch Dispersion and Dough during Heating: Master Curves of Complex Viscosity, J. Tattiyakul, H-L. Liao, and M.A. Rao The Role of Rheology in Extrusion, O. H. Campanella, P. X. Li, K. A. Ross, and M. R. Okos Non-Linear Viscoelasticity Modeling of Vegetable Protein-Stabilized Emulsions, C. Gallegos, J. M. Franco, J. M. Madiedo, A. Raymundo, and I. Sousa Rheological Properties of Food Materials Under Standard and High Pressure and Temperature Conditions, A. Gaspar-Rosas Rheo-Reactor for Studying Food Processes: Specific Cases of Foaming and Freezing, L. Choplin, B. E. Chavez-Montes, and E. Schaer FOOD STRUCTURE Levels of Structure and the Mechanical Properties of Solid Foods, M. Peleg Structure-Functionality Relationships in Foods, A. H. Barret Structure and Food Engineering, J.M. Aguilera Viewing Food Microstructure, J. C. G. Blonk THERMAL PROCESSING AND PACKAGING Active Packaging: Science and Application, M. L. Rooney Mass Transfer in Food/Plastic Packaging Systems, R. Gavara and R. Catala Mass Transport within Edible and Biodegradable Protein Based Materials: Application to the Design of Active Biopackaging, S. Guilbert, A. Redl, and N. Gontard Cooling Uniformity in Overpressure Retorts Using Water Spray and Full Immersion, M. A. Tung, G. F. Morello, A. T. Paulson, and I. J. Britt Contribution to Kinetics for the Development of Food Sterilization Processes at High Temperatures: IATA-CSIC Results, M. Rodrigo, A. Martinez, and C. Rodrigo MINIMAL PROCESSING Shelf-Life Prediction of Minimally Processed Chilled Foods, B. M. McKenna Update on Hurdle Technology, L. Leistner Microbial Behavior Modeling as a Tool in the Design and Control of Minimally Processed Foods, S. M. Alzamora and A. Lopez-Malo The Role of an Osmotic Step: Combined Processes to Improve Quality and Control Functional Properties in Fruits and Vegetables, D. Torreggiani and G. Bertolo Approaches for Safety Assessment of Minimally Processed Fruits and Vegetables, M. S. Tapia and J. Welti-Chanes EMERGING TECHNOLOGIES Membrane Permeabilization and Inactivation Mechanisms of Biological Systems by Emerging Technologies, D. Knorr, V. Heinz, A. Angersbach, and D-U. Lee Innovative Fruit Preservation Methods using High Pressure, E. Palou, A. Lopez-Malo, and J. Welti-Chanes Production Issues Related to UHP Food, E. Y. Ting and R. G. Marshall Enhanced Thermal Effects Under Microwave Heating Conditions, H. S. Ramaswamy, T. Koutchma, and S. Tajchakavit Applications of Low Intensity Ultrasonics in the Dairy Industry, A. Mulet, J. A. Carcel, J. Benedito, and N. Sanjuan Ohmic Heating and Moderate Electric Field (MEF) Processing, S. K. Sastry, A. Yousef, H-Y. Cho, R. Unal, S. Salengke, W-C. Wang, M. Lima, S. Kulshrestha, P. Wongsa-Ngasri, and I. Sensoy Design, Construction and Evaluation of a Sanitary Pilot Plant System (PEF), Q. H. Zhang, C. B. Streaker, Jr., and H. W. Yeom PROCESS CONTROL Recent Advances in Simulation for the Process Industries, D. Bogle Simulation-Based Design of Food Products and Processes, A.K. Datta Modeling and Simulation of Reactive and Separation Food Bed Processes, F. Lopez-Isunza, E. S. Perez-Cisneros, and S. I Flores y De Hoyos Modeling Bean Heating during Batch Roasting of Coffee Beans, H. G. Schwartzberg FOOD BIOTECHNOLOGY New Frontiers for Food Processing: The Impact of Changes in Agrobiotechnology, R. Quintero-Ramirez Novel and Potential Applications of alpha-Amylases in the Food Industry, G. Saab-Rincon, G. Del Rio, R. I. Santamaria, M. L. Diaz, X. Soberon, and A. Lopez-Munguia Modelling Conditions Affecting the Production of a Bacteriocin by Enterococcus faecium UQ1 and the Kinetics of the Bacteriocin Antilisterial Activity, B. Garcia-Almendarez, J. Ibarra-Silva, L. Mayorga-Martinez, J. Dominguez-Dominguez, and C. Regalado ENVIRONMENTAL Clean Technology in the Food Manufacturing Industry, P. J. Lillford and M. F. Edwards Pest Control in the Food Industry: Raw Materials Control, P. Valle-Vega SPACE MISSIONS Storage Stability and Nutritive Value of Food for Long-Term Manned Space Missions, D. Zasypkin and T-C. Lee Preservation Methods Utilized for Space Food, Y. Vodovotz and C. T. Bourland NASA Food Technology Commercial Space Center, D. G. Olson EDUCATION Role of the Internet in Food Engineering Teaching, R. P. Singh Teaching Food Engineering with the Aid of Multmedia, M. Lopez-Leiva A Low-Cost, Versatile Laboratory Experiment in Food Engineering Using the Internet, F. Courtois and R. P. Singh Toward a Virtual Cooperative Training Program in Food Engineering, E. Parada-Arias, G. F. Guterrez-Lopez, and C. Odorica-Vargas
A 64‐year‐old male patient presented with a 2‐month history of a generalized mucocutaneous eruption characterized by suspected keratoacanthomas (KAs), umbilicated papules, and small follicular papules, which mainly involved the face, upper limbs, and trunk; the oral mucosa was affected as well. The presence of HPV‐16 DNA harbored in GEKA lesions does not allow any conclusive consideration on the etiological role of HPV infection and the role of HPV in keratoacanthomas remains thus elusive. However, its potential involvement in the pathogenesis of this disorder supports the retinoids as the first therapeutic option. Retinoids could be effective in GEKA treatment not only because of their antitumor properties but also by altering keratinization and inhibiting HPV replication and assembly. In keeping with this, an inverse relation has been observed between concentration of retinoids and HPV DNA within infected epithelial cells.15 We recommend the evaluation of the role of HPV infection in GEKA as meritorious of further investigation.