Modern, data-driven medical research requires the processing of sensitive health data on a large scale. However, this data is subject to special protection under the GDPR, which is why processing regularly raises data protection concerns in practice. These concerns are particularly prevalent when sensitive personal data is processed without informed consent. This article analyses options for data processing in the field of medical research without consent and describes the legal framework for anonymisation under the GDPR, the national Austrian implementation of the research exemption, and their interaction. -- Moderne, datengetriebene medizinische Forschung erfordert die Verarbeitung sensibler Gesundheitsdaten in grossem Ausmass. Diese sind im System der DSGVO jedoch besonders geschützt, weswegen einer rechtssicheren Verarbeitung in der Praxis regelmässig datenschutzrechtliche Bedenken entgegenstehen. Diese Bedenken bestehen insbesondere bei Verarbeitung sensibler personenbezogener Daten ohne informierte Einwilligung. Dieser Beitrag analysiert daher Möglichkeiten zur Datenverarbeitung im Bereich der medizinischen Forschung fernab der Einwilligung und beschreibt hierfür das rechtlic
This study presents the first ex-vivo positronium imaging of human tissues using the modular J-PET scanner with the $^{44}$Sc radionuclide. The $^{44}$Sc isotope was produced via the $^{44}$Ca(p, n)$^{44}$Sc nuclear reaction and used to perform positronium imaging of phantom composed of human adipose tissue, cardiac myxoma tissue, thrombi blood clot, and also porous polymer XAD4, and a certified reference material (CRM) made from fused silica. The experiment demonstrates the suitability of $^{44}$Sc as a positron source for positronium imaging. The performance of J-PET for positronium imaging with $^{44}$Sc was validated by proper reconstruction of the mean orthopositronium lifetime for CRM material and XAD-4 polymer. The mean ortho-positronium (oPs) lifetimes determined for adipose tissue, cardiac myxoma tissues and thrombi were consistent with results of previous experiments. The study highlights the potential $^{44}$Sc radionuclide for positronium lifetime imaging (PLI).
Deep learning advanced to one of the most important technologies in almost all medical fields. Especially in areas, related to medical imaging it plays a big role. However, in interventional radiotherapy (brachytherapy) deep learning is still in an early phase. In this review, first, we investigated and scrutinised the role of deep learning in all processes of interventional radiotherapy and directly related fields. Additionally we summarised the most recent developments. To reproduce results of deep learning algorithms both source code and training data must be available. Therefore, a second focus of this work was on the analysis of the availability of open source, open data and open models. In our analysis, we were able to show that deep learning plays already a major role in some areas of interventional radiotherapy, but is still hardly presented in others. Nevertheless, its impact is increasing with the years, partly self-propelled but also influenced by closely related fields. Open source, data and models are growing in number but are still scarce and unevenly distributed among different research groups. The reluctance in publishing code, data and models limits reproducibility
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It's early, but the plan is to reduce dependency on Nvidia and Huawei