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Large Language Models deployed as question answering tools require robust calibration to avoid overconfidence. We systematically evaluate how reasoning capabilities and budget affect confidence assessment accuracy, using the ClimateX dataset (Lacombe et al., 2023) and expanding it to human and planetary health. Our key finding challenges the "test-time scaling" paradigm: while recent reasoning LLMs achieve 48.7% accuracy in assessing expert confidence, increasing reasoning budgets consistently impairs rather than improves calibration. Extended reasoning leads to systematic overconfidence that worsens with longer thinking budgets, producing diminishing and negative returns beyond modest computational investments. Conversely, search-augmented generation dramatically outperforms pure reasoning, achieving 89.3% accuracy by retrieving relevant evidence. Our results suggest that information access, rather than reasoning depth or inference budget, may be the critical bottleneck for improved confidence calibration of knowledge-intensive tasks.
The Neomycin resistance cassette (Neo+) is commonly inserted in the genome of mice to generate knock-out (KO) models. The effect of gene deletion on social behaviors in mice is controversial between studies using different Neo+ and Neo-mouse lines, particularly Arc/Arg3.1 KO lines. In this study, we identified severe maternal behavior impairments in Neo+, but not Neo-Arc/Arg3.1 KO dams. These deficits resulted from reduced sociability and abnormal social information processing in Neo+ Arc/Arg3.1 KO dams, exacerbated by social communication impairments in pups. The expression of the Neo cassette product did not cause cytotoxicity, but led to altered ERK signaling, gene expression, and oxytocin system. However, oxytocin administration did not improve social impairments in Neo+ Arc/Arg3.1 KO animals. Interestingly, early social environment enrichment enhanced social interaction with familiar, but not unfamiliar conspecifics or maternal behavior. Overall, our findings reveal a major impact of the Neo cassette on behaviors, particularly social behaviors, in Arc/Arg3.1 KO mice, underscoring the need to re-examine phenotypes of animal models carrying the Neo cassette in neuroscience resea
Cell-free massive MIMO (multiple-input multiple-output) enhances spectral and energy efficiency compared to conventional cellular networks by enabling joint transmission and reception across a large number of distributed access points (APs). Since these APs are envisioned to be low-cost and densely deployed, hardware impairments, stemming from non-ideal radio-frequency (RF) chains, are unavoidable. While existing studies primarily address hardware impairments on the access side, the impact of hardware impairments on the wireless fronthaul link has remained largely unexplored. In this work, we fill this important gap by introducing a novel amplify-and-forward (AF) based wireless fronthauling scheme tailored for cell-free massive MIMO. Focusing on the uplink, we develop an analytical framework that jointly models the hardware impairments at both the APs and the fronthaul transceivers, derives the resulting end-to-end distorted signal expression, and quantifies the individual contribution of each impairment to the spectral efficiency. Furthermore, we design distortion-aware linear combiners that optimally mitigate these effects. Numerical results demonstrate significant performance ga
Millions of people live with cognitive impairment from Alzheimer's disease and related dementias (ADRD). Voice-enabled smart home systems offer promise for supporting daily living but rely on automatic speech recognition (ASR) to transcribe their speech to text. Prior work has shown reduced ASR performance for adults with cognitive impairment; however, the acoustic factors underlying these disparities remain poorly understood. This paper evaluates ASR performance for 83 older adults across cognitive groups (cognitively normal, mild cognitive impairment, dementia) reading commands to a voice assistant (Amazon Alexa). Results show that ASR errors are significantly higher for individuals with dementia, revealing a critical usability gap. To better understand these disparities, we conducted an acoustic analysis of speech features and found that a speaker's intensity, voice quality, and pause ratio predicted ASR accuracy. Based on these findings, we outline HCI design implications for AgeTech and voice interfaces, including speaker-personalized ASR, human-in-the-loop correction of ASR transcripts, and interaction-level personalization to support ability-based adaptation.
Motor impairments, including tremor, bradykinesia, gait abnormalities, and postural instability, are common across many neurological and movement-related conditions. Conventional clinical assessments are often intermittent and may fail to capture subtle temporal variations in motor behavior. While wearable IMUs and third-person video have shown promise for objective motor assessment, third-person recordings raise privacy concerns and require constrained acquisition setups. In contrast, egocentric vision provides a more naturalistic and privacyaware alternative. In this work, we introduce EgoInertia-MI, a multimodal benchmark dataset combining synchronized egocentric video and wearable IMU signals for motor impairment analysis. The dataset contains 19 upper- and lower-body activities performed by healthy volunteers simulating varying levels of motor impairment severity levels: no impairment, mild impairment, and severe impairment. We establish two benchmark tasks: action recognition and motor impairment severity estimation, and evaluate multiple unimodal and multimodal baselines. Experimental results show that egocentric video provides strong cues for motor impairment assessment, wh
Dementia is a progressive condition that impairs an individual's cognitive health and daily functioning, with mild cognitive impairment (MCI) often serving as its precursor. The prediction of MCI to dementia conversion has been well studied, but previous studies have almost always focused on traditional Machine Learning (ML) based methods that require sharing sensitive clinical information to train predictive models. This study proposes a privacy-enhancing solution using Federated Learning (FL) to train predictive models for MCI to dementia conversion without sharing sensitive data, leveraging socio demographic and cognitive measures. We simulated and compared two network architectures, Peer to Peer (P2P) and client-server, to enable collaborative learning. Our results demonstrated that FL had comparable predictive performance to centralized ML, and each clinical site showed similar performance without sharing local data. Moreover, the predictive performance of FL models was superior to site specific models trained without collaboration. This work highlights that FL can eliminate the need for data sharing without compromising model efficacy.
This study presents an approach for collecting speech samples to build Automatic Speech Recognition (ASR) models for impaired speech, particularly, low-resource languages. It aims to democratize ASR technology and data collection by developing a "cookbook" of best practices and training for community-driven data collection and ASR model building. As a proof-of-concept, this study curated the first open-source dataset of impaired speech in Akan: a widely spoken indigenous language in Ghana. The study involved participants from diverse backgrounds with speech impairments. The resulting dataset, along with the cookbook and open-source tools, are publicly available to enable researchers and practitioners to create inclusive ASR technologies tailored to the unique needs of speech impaired individuals. In addition, this study presents the initial results of fine-tuning open-source ASR models to better recognize impaired speech in Akan.
In the study, the device of social robot was designed for visually impaired users, and along with a mobile application for provide functions to assist their lives. Both physical and mental conditions of visually impaired users are considered, and the mobile application provides functions: photo record, mood lift, greeting guest and today highlight. The application was designed for visually impaired users, and uses voice control to provide a friendly interface. Photo record function allows visually impaired users to capture image immediately when they encounter danger situations. Mood lift function accompanies visually impaired users by asking questions, playing music and reading articles. Greeting guest function answers to the visitors for the inconvenient physical condition of visually impaired users. In addition, today highlight function read news including weather forecast, daily horoscopes and daily reminder for visually impaired users. Multiple tools were adopted for developing the mobile application, and a website was developed for caregivers to check statues of visually impaired users and for marketing of the application.
Navigation in new or unknown environments is vital, especially for visually impaired individuals. While many solutions exist, few are tailored to specific disabilities, often due to limited collaboration with handicap users in the design process. This article examines 7 tools that enable visually impaired users to participate in design, selected through a systematic review and analyzed for affinities, differences, and applications. The study suggests correlations among the tools, offering a foundation for a methodology that enhances inclusive design and accessibility.
In this article, we provide an experimental observation: Deep neural network (DNN) based speech quality assessment (SQA) models have inherent latent representations where many types of impairments are clustered. While DNN-based SQA models are not trained for impairment classification, our experiments show good impairment classification results in an appropriate SQA latent representation. We investigate the clustering of impairments using various kinds of audio degradations that include different types of noises, waveform clipping, gain transition, pitch shift, compression, reverberation, etc. To visualize the clusters we perform classification of impairments in the SQA-latent representation domain using a standard k-nearest neighbor (kNN) classifier. We also develop a new DNN-based SQA model, named DNSMOS+, to examine whether an improvement in SQA leads to an improvement in impairment classification. The classification accuracy is 94% for LibriAugmented dataset with 16 types of impairments and 54% for ESC-50 dataset with 50 types of real noises.
Individuals who are differently-able in vision cannot proceed with their day-to-day activities as smoothly as other people do. Especially independent walking is a hard target to achieve with their visual impairment. Assistive electronic travel aids equipped with different types of sensors are designed for visually impaired persons to assist their safe navigation. The amount of research on combining multiple sensors in assistive navigation aids for visually impaired navigation is limited. Most work is targeted at sensor integration but not at sensor fusion. This paper aims to address how sensor fusion and integration will be used to improve the sub-processes of visually impaired navigation and the way to evaluate the sensor fusion-based approach for visually impaired navigation which consists of several contributions to field sensor fusion in visually impaired navigation such as a novel homogeneous sensor fusion algorithm based on extended Kalman filter, a novel heterogeneous sensor integration approach, and a complementary sensor fusion algorithm based on error state extended Kaman filter. Overall this research presents a novel navigational framework to integrate obstacle detection
Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population, especially when periodic assessments are needed. The problem is compounded by the fact that people have differing patterns of cognitive impairment as they progress to different forms of dementia. This paper presents a novel scheme by which individual-specific patterns of impairment can be identified and used to devise personalized tests for periodic follow-up. Patterns of cognitive impairment are initially learned from a population cluster of combined normals and MCIs, using a set of standardized cognitive tests. Impairment patterns in the population are identified using a 2-step procedure involving an ensemble wrapper feature selection followed by cluster identification and analysis. These patterns have been shown to correspond to clinically accepted variants of MCI, a prodrome of dementia. The learned clusters of patterns can subsequently be used to identify the most likely route of cognitive impairment, even for pre-symptomatic and apparently normal
Speech is essential for human communication, yet millions of people face impairments such as dysarthria, stuttering, and aphasia conditions that often lead to social isolation and reduced participation. Despite recent progress in automatic speech recognition (ASR) and text-to-speech (TTS) technologies, accessible web and mobile infrastructures for users with impaired speech remain limited, hindering the practical adoption of these advances in daily communication. To bridge this gap, we present SpeechAgent, a mobile SpeechAgent designed to facilitate people with speech impairments in everyday communication. The system integrates large language model (LLM)- driven reasoning with advanced speech processing modules, providing adaptive support tailored to diverse impairment types. To ensure real-world practicality, we develop a structured deployment pipeline that enables real-time speech processing on mobile and edge devices, achieving imperceptible latency while maintaining high accuracy and speech quality. Evaluation on real-world impaired speech datasets and edge-device latency profiling confirms that SpeechAgent delivers both effective and user-friendly performance, demonstrating it
Despite recent advances in automated driving technology, impaired driving continues to incur a high cost to society. In this paper, we present a driving dataset designed to support the study of two common forms of driver impairment: alcohol intoxication and cognitive distraction. Our dataset spans 23.7 hours of simulated urban driving, with 52 human subjects under normal and impaired conditions, and includes both vehicle data (ground truth perception, vehicle pose, controls) and driver-facing data (gaze, audio, surveys). It supports analysis of changes in driver behavior due to alcohol intoxication (0.10\% blood alcohol content), two forms of cognitive distraction (audio n-back and sentence parsing tasks), and combinations thereof, as well as responses to a set of eight controlled road hazards, such as vehicle cut-ins. The dataset will be made available at https://toyotaresearchinstitute.github.io/IDD/.
With mobile apps rapidly permeating all aspects of daily living with use by all segments of the population, it is crucial to support the evaluation of app usability for specific impaired users to improve app accessibility. In this work, we examine the effects of using our \textit{augmented virtuality} impairment simulation system--\textit{Empath-D}--to support experienced designer-developers to redesign a mockup of commonly used mobile application for cataract-impaired users, comparing this with existing tools that aid designing for accessibility. We show that the use of augmented virtuality for assessing usability supports enhanced usability challenge identification, finding more defects and doing so more accurately than with existing methods. Through our user interviews, we also show that augmented virtuality impairment simulation supports realistic interaction and evaluation to provide a concrete understanding over the usability challenges that impaired users face, and complements the existing guidelines-based approaches meant for general accessibility.
Speech impairments resulting from congenital disorders, such as cerebral palsy, down syndrome, or apert syndrome, as well as acquired brain injuries due to stroke, traumatic accidents, or tumors, present major challenges to automatic speech recognition (ASR) systems. Despite recent advancements, state-of-the-art ASR models like Whisper still struggle with non-normative speech due to limited training data availability and high acoustic variability. Moreover, collecting and annotating non-normative speech is burdensome: speaking is effortful for many affected individuals, while laborious annotation often requires caregivers familiar with the speaker. This work introduces a novel ASR personalization method based on Bayesian Low-rank Adaptation for data-efficient fine-tuning. We validate our method on the English UA-Speech dataset and a newly collected German speech dataset, BF-Sprache, from a child with structural speech impairment. The dataset and approach are designed to reflect the challenges of low-resource settings that include individuals with speech impairments. Our method significantly improves ASR accuracy for impaired speech while maintaining data and annotation efficiency,
Mobile games are becoming a vital medium for social interaction, offering a platform that transcends geographical boundaries. An increasing number of visually impaired individuals are engaging in mobile gaming to connect, collaborate, compete, and build friendships. In China, visually impaired communities face significant social challenges in offline settings, making mobile games a crucial avenue for socialization. However, the design of mobile games and their mapping to real-world environments significantly shape their social gaming experiences. This study explores how visually impaired players in China navigate socialization and integrate into gaming communities. Through interviews with 30 visually impaired players, we found that while mobile games fulfill many of their social needs, technological barriers and insufficient accessibility features, and internal community divisions present significant challenges to their participation. This research sheds light on their social experiences and offers insights for designing more inclusive and accessible mobile games.
This letter studies the low-complexity channel estimation for orthogonal time frequency space (OTFS) in the presence of hardware impairments. Firstly, to tackle the computational complexity of channel estimation, the basis expansion model (BEM) is utilized. Then, the mean square error (MSE) of the estimated channel is theoretically derived, revealing the effects of hardware impairments on channel estimation. Based on the estimated channel, the minimum mean square error (MMSE) detector is adopted to analyze the impacts of imperfect hardware on the bit error rate (BER). Finally, the numerical results validate the correctness of our theoretical analysis of the MSE for channel estimation and lower bound of the BER, and also demonstrate that even minor hardware impairments can significantly degrade the performance of the OTFS system.
Individuals with vision impairments employ a variety of strategies for object identification, such as pans or soy sauce, in the culinary process. In addition, they often rely on contextual details about objects, such as location, orientation, and current status, to autonomously execute cooking activities. To understand how people with vision impairments collect and use the contextual information of objects while cooking, we conducted a contextual inquiry study with 12 participants in their own kitchens. This research aims to analyze object interaction dynamics in culinary practices to enhance assistive vision technologies for visually impaired cooks. We outline eight different types of contextual information and the strategies that blind cooks currently use to access the information while preparing meals. Further, we discuss preferences for communicating contextual information about kitchen objects as well as considerations for the deployment of AI-powered assistive technologies.
The continuing growth in cannabis legalization necessitates the development of rapid, objective methods for assessing impairment to ensure public and occupational safety. Traditional measurement techniques are subjective, time-consuming, and do not directly measure physical impairment. This study introduces objective metrics derived from eye-tracking analytics to address these limitations. We employed a head-mounted display to present 20 subjects with smooth pursuit performance, horizontal saccade, and simple reaction time tasks. Individual and group performance was compared before and after cannabis use. Results demonstrated significant changes in oculomotor control post-cannabis consumption, with smooth pursuit performance showing the most substantial signal. The objective eye-tracking data was used to develop supervised learning models, achieving a classification accuracy of 89% for distinguishing between sober and impaired states when normalized against baseline measures. Eye-tracking is the optimal candidate for a portable, rapid, and objective tool for assessing cannabis impairment, offering significant improvements over current subjective and indirect methods.