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The data we present are part of the long-term project SLAM - Long Term Ecological Study of the Impacts of Climate Change in the natural forest of Azores, which was established in 2012 to monitor arthropod communities in Azorean forest habitats using standardised long-term ecological sampling. The main aim of this project is to understand how major biodiversity erosion drivers, including habitat degradation, biological invasions and climate-related pressures, affect the distribution, abundance and diversity of Azorean arthropods through time. Long-term monitoring is particularly relevant on oceanic islands, where biodiversity change may be expressed more strongly through species turnover, shifts in community composition and increases in introduced taxa than through immediate declines in total species richness. The SLAM framework also contributes to the early detection and documentation of new species occurrences, thereby improving baseline knowledge for conservation planning, biodiversity assessment and biosecurity. Sampling relies on passive flight-interception SLAM (Sea, Land and Air Malaise) traps, which are operated continuously and serviced at regular intervals to provide comparable seasonal and interannual samples. We sampled 17,064 specimens from samples from the years 2015-2021 out of which 16,491 were identified to the level of species (96.6%) or even subspecies (326 individuals) and 247 were identified to the order, family or genus level. The identified specimens belong to 17 unique orders, 82 families, 156 genera and 165 species and eight subspecies. Of these species and subspecies, 14 were endemic, 49 were native non-endemic, 86 were introduced and 24 have uncertain colonisation status.A total of 26 species were recorded for the first time on Graciosa Island, but none represents a new record for the Azores Archipelago. Amongst these newly-recorded species, two are Azorean endemics, five are native non-endemics, 16 are introduced and three have uncertain colonisation status, with most detected at very low abundance.New island records on Graciosa Island comprise nine spiders (Order Araneae), including two Azorean endemic spiders recorded for the first time on Graciosa, Neon acoreensis (jumping spider; Salticidae) and Savigniorrhipis acoreensis (dwarf sheet spider; Linyphiidae). The remaining newly-recorded spiders are: Agyneta decora (dwarf sheet spider; Linyphiidae), Enoplognatha mandibularis (cobweb spider; Theridiidae), Haplodrassus signifier (ground spider; Gnaphosidae), Neriene clathrata (sheetweb spider; Linyphiidae), Orchestina furcillata (goblin spider; Oonopidae), Theridion melanostictum (cobweb spider; Theridiidae) and Zelotes aeneus (ground spider; Gnaphosidae).New records also include eight beetles (Coleoptera): Amischa forcipata (rove beetle; Staphylinidae), Brassicogethes aeneus (pollen beetle; Nitidulidae), Carpelimus troglodytes troglodytes (rove beetle; Staphylinidae), Cathormiocerus curvipes (weevil; Curculionidae), Omosita discoidea (sap beetle; Nitudulidae), Phyllotreta procera (flea beetle; Chrysomelidae), Ptenidium pusillum (featherwing beetle; Ptiliidae) and Quedius curtipennis (rove beetle; Staphylinidae).Additional new records comprise one millipede (Diplopoda), Cylindroiulus latestriatus (julid millipede; Diplopoda, Julida) and three true bugs (Hemiptera): Buchananiella continua (minute pirate bug; Anthocoridae), Empicoris rubromaculatus (thread-legged bug; Reduviidae) and Pilophorus confusus (plant bug; Miridae).Further additions are one ant (Hymenoptera), Hypoponera eduardi (ant; Formicidae), one booklouse (Psocodea), Lepinotus reticulatus (booklouse; Trogiidae), two thrips (Thysanoptera), Anisopilothrips venustulus (thrips; Thripidae) and Ceratothrips ericae (thrips; Thripidae) and one bush-cricket (Orthoptera), Phaneroptera nana (katydid/bush-cricket; Tettigoniidae).

Global demand for ruminant milk-based products is increasing, contributing to increases in associated environmental impacts. Yet, most efforts to reduce the total environmental impact of dairy production are based on livestock breeding and manipulation of feed and manure systems. Despite the critical need for low-environmental impact breeding, life cycle assessment (LCA) has not been significantly utilized for forage and livestock trait prioritization. By combining LCA and machine learning, we inventory reductions in footprints of grass-fed dairy systems achievable by selective breeding. To measure the environmental impacts of traits and other farm changes, a pasture-centric dairy system representative of Ireland was modelled using the GOBLIN model. Milk produced in ryegrass-based dairy systems in Ireland was associated with environmental impacts of 1.08 kg CO2-eq (global warming), 0.0066 kg PO4-eq (eutrophication), 0.013 kg SO2-eq (acidification), and 1.62 MJ-eq (fossil resource depletion) per kg fat- and protein-corrected milk (FPCM), translating to annual per-hectare loads of 9281.21 kg CO2-eq, 56.75 kg PO4-eq, 108.21 kg SO2-eq, and 14,025.16 MJ-eq, respectively. Using a machine learning model trained on farm-level LCA outputs, complementarities and trade-offs were revealed across 10,000 graduated scenarios analyzed. The XGBoost Regressor achieved an outstanding R2 value of 99 % in estimating the LCA impacts. Principal component analysis and explainable artificial intelligence analyses identified dry matter digestibility, crude protein, and chemical nitrogen use as key drivers of environmental impacts in dairy systems. By optimizing input parameters, the environmental impacts of grass-based milk can be substantially reduced by breeding for 'LCA-designed ideotypes'. The optimal ryegrass ideotype identified for grass-based dairy systems can reduce; (a) global warming potential by 36.7 %, (b) acidification potential by 31 %, (c) eutrophication potential by 29 %, and (d) fossil resource depletion by 11 %, compared to current levels. We conclude that the environmental performance of ryegrass-based dairy systems can be substantially increased by new LCA-designed forage ideotypes. A more systems-based approach to livestock and forage breeding is therefore needed, as a sole focus on low-footprint livestock may overlook critical gains from forage grass improvement.

The Heartland virus (HRTV) is a tick-borne human pathogenic phlebovirus that primarily causes leukopenia and thrombocytopenia. It is transmitted by Amblyomma americanum type of tick, that is, notable for their aggressive biting behavior, affinity for human hosts, and high prevalence. Developing vaccines or immunizations against HRTV is gaining importance as a public-health preventive strategy. The current study was planned to prioritize a multi-epitope stable mRNA vaccine model against HRTV from lead B-cell and T-cell epitopes (with IC50 < 100 nM) of HRTV proteome following advanced immunoinformatics approaches. Model constructs were designed by linking the most potent, nonallergenic epitopes along with incorporation of human ribosomal protein adjuvant for immune response enhancement. The immunogenic potential of the coding vaccine molecule was examined via molecular docking against toll-like receptors immune receptors followed by normal mode analysis and molecular dynamics simulations-based energy minimization, molecular stability, and flexibility assessments. A robust, stable circular mRNA precursor of multi-epitopes vaccine model was designed by incorporating the Kozak consensus sequence, a start codon, and essential elements such as MHC class I trafficking domain (MITD), tPA, Goblin 5' and 3' Untranslated Region (UTRs), and a poly (A) tail. This strategic amalgamation ensures elevated immunogenicity and predicts a promising circular mRNA vaccine model against HRTV. The immune simulation predicted that the designed model vaccine is capable to elicit cell-mediated and humoral immune responses. The predicted circular mRNA vaccine precursor model is promising against HRTV to examine experimentally for its immunogenicity and safety features.

Global and national environmental targets for the Agriculture, Forestry and Other Land Use (AFOLU) sector need to be reconciled with increasing food and protein demands of a growing global population. Meeting climate targets in AFOLU is a tremendous challenge in countries with high ruminant livestock production and small forest carbon sinks. Using GOBLIN, an integrated assessment model that utilises a back-casting approach, 2187 future AFOLU configuration scenarios are explored to investigate whether current levels of bovine protein production in Ireland are compatible with net zero greenhouse gas (GHG) emissions by 2050. Seven proven GHG mitigation measures are combined at three levels of ambition and screened according to three definitions of net zero based on the GWP100 metric, with a focus on the integration of clover-based grasslands. Net zero was achieved in 19&#xa0;% of scenarios when all GHGs require balancing by 2050. The current livestock herd configuration was incompatible with net zero, which required at least 1.5 million ha of grassland to be diverted from livestock production towards climate-positive land uses, including afforestation of close to 10&#xa0;% of terrestrial land area by 2050. When applying less stringent net zero definitions based on a split gas approach, up to 63&#xa0;% of explored scenarios achieved net zero. Independent of net zero definition (which must be internationally fair and transparent), results indicate that bovine protein production can only be maintained through very high deployment of ambitious technical abatement measures, alongside major land use transformation requiring large-scale structural changes in the agriculture sector.

Two new species of the genus Trilacuna Tong & Li, 2007, T.manhao Tong & Li, sp. nov. (&#x2642;&#x2640;) and T.mopanshan Tong & Li, sp. nov. (&#x2642;&#x2640;), are described from Yunnan, China. Descriptions, diagnoses, photomicroscopy images and a key to species of Yunnan Province are provided.

Dengue is an important public health problem, which caused by the dengue virus (DENV), a single-stranded RNA virus consisted of four serotypes. Central nervus system (CNS) impairment in dengue usually results from DENV-2 or DENV-3 infection, which lead to life-threatening outcomes. Furthermore, neurological complications due to DENV-1 was rare especially in adult patients. A 44-year-old man without comorbidities had lethargy after hyperpyrexia and a positive DENV NS1 antigen was detected for confirming the diagnosis of dengue on day 8 of onset. Then logagnosia, decreased muscle strength, delirium and irritability were occurred even radiographic examination were normal. He was treated with low-dose hormone, sedatives and gamma goblin with a short duration of 6 days. The cerebrospinal fluid (CSF) tests were persistent normal. However, presence of DENV-1 RNA was confirmed both in CSF and serum. Furthermore, the complete sequence of the DENV isolated from the patient's serum was performed (GenBank No.: MW261838). The cytokines as IL-6, IL-10 and sVCAM-1 were increased in critical phase of disease. Finally, the patient was discharged on day 24 of onset without any neurological sequelae. Encephalopathy caused by a direct CNS invasion due to DENV-1 during viremia was described in an adult patient. Treatment with low-dose hormone and gamma goblin was helpful for admission.

The spider genus Trilacuna Tong & Li, 2007, currently comprises 32 species known from China, of which 15 species are from Yunnan and one species, i.e. T. wumanshan Tong, Yang & Zhang, 2023 is recorded from the Nangunhe Nature Reserve, Yunnan. Two new Trilacuna species, Trilacuna jimengi Dai & Tong, sp. nov. (&#x2642;&#x2640;) and Trilacuna nangunhe Dai & Tong, sp. nov. (&#x2642;&#x2640;), are described, based on specimens collected from the Nangunhe Nature Reserve, Yunnan Province. Morphological descriptions and photomicroscopy images of the new species are given.

The genus Orchestina is recorded for the first time from Xizang, China. One known species and three new species are reported: Orchestinacolubrina Liu, Henrard & Xu, 2019 (&#x2642;&#x2640;), Orchestinalini Tong & Li, sp. nov. (&#x2642;&#x2640;), Orchestinawuzu Tong & Li, sp. nov. (&#x2642;&#x2640;) and Orchestinayigong Tong & Li, sp. nov. (&#x2642;).

Post-transplant diabetes mellitus (PTDM) is a common, dynamic complication after kidney transplantation (KT) that may resolve over time. To better understand and prevent PTDM, we analyzed its prevalence, evolution, and influencing factors. Data from the French national ASTRE database at different post-transplantation periods (P) were analyzed. PTDM was defined by fasting blood glucose (FBG) &#x2265;1.26&#xa0;g/L, HbA1c&#xa0;&#x2265;&#xa0;6.5%, or the use of hypoglycemic medications in kidney transplant recipients without diabetes. Patient trajectories were identified using group-based trajectory models (GBTM), and associated factors were examined. Among 2898 patients, PTDM prevalence was 27.3% at P1 (>M2, &#x2264;M6), 21.3% at P2 (>M6, &#x2264;M18), 19.8% at P3 (>M18, &#x2264;M30), and 19.9% at P4 (>M30, &#x2264;M42). Analysis of 1825 patients identified four trajectories: no PTDM (67%), late-onset PTDM (6%), remission after P1 (10%), and early, persistent PTDM (17%). Late-onset PTDM was linked to history of cardiovascular disease, higher BMI at transplantation, HCV positive status, and weight gain. Early, persistent PTDM was associated with older age, higher BMI, HVC positive status, history of cardiovascular disease, and tacrolimus use. PTDM remission was linked to lower BMI. Corticosteroids contributed to both late-onset and persistent PTDM, while switching between tacrolimus and cyclosporine did not significantly affect progression. This study confirmed the high prevalence and dynamic nature of PTDM after transplantation, emphasizing the critical role of pretransplant cardiovascular disease, BMI, and early post-transplant weight gain in the onset or remission of PTDM.

Four species of the genus Trilacuna Tong & Li, 2007 from Xizang, China are recognized, including three new species and one newly recorded species: T.bangla Grismado & Ram&#xed;rez, 2014, T.mainling Tong & Li, sp. nov. (&#x2642;&#x2640;), T.metok Tong & Li, sp. nov. (&#x2642;&#x2640;) and T.zayu Tong & Li, sp. nov. (&#x2642;&#x2640;). Descriptions, diagnoses and photomicroscopy images are provided.

Eight new species and one known species of the oonopid spider genus Orchestina Simon, 1882 are described or recorded based on material collected from forest canopy of Xishuangbanna, Yunnan Province, southwestern China: O. alata sp. nov. (&#x2642;&#x2640;), O. aureola Tong & Li, 2011 (&#x2642;&#x2640;), O. caixiaae Tong & Li, sp. nov. (&#x2642;&#x2640;), O. longituba Tong & Li, sp. nov. (&#x2642;&#x2640;), O. qingyuani Tong & Li, sp. nov. (&#x2642;&#x2640;), O. subconcava Tong & Li, sp. nov. (&#x2642;&#x2640;), O. sublongituba Tong & Li, sp. nov. (&#x2642;&#x2640;), O. tentoria Tong & Li, sp. nov. (&#x2642;&#x2640;) and O. xuexing Tong & Li, sp. nov. (&#x2642;&#x2640;). An identification key to these nine species is provided.

Three new species of Gamasomorpha Karsch, 1881 are described: G. bakeri Tong & H&#xf6;rweg, sp. nov. (&#x2642;&#x2640;) (Philippines), G. fortdekock Tong & H&#xf6;rweg, sp. nov. (&#x2642;) (Indonesia), and G. jacobsoni Tong & H&#xf6;rweg, sp. nov. (&#x2642;&#x2640;) (Indonesia). Additionally, Xestaspis shoushanensis Tong & Li, 2014 is recorded for the first time from Sumatra, Indonesia, and transferred to Gamasomorpha with a new combination established: Gamasomorpha shoushanensis (Tong & Li, 2014), comb. nov. Descriptions, diagnoses and photomicroscopy images are provided.