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In romantic relationships between men and women, women tend to report lower sexual desire than men, which is often seen as an individual or relationship issue, rather than one explained by contextual factors, such as structural gender inequities. Extending past research, we focused on (un)equal division of household labor as one example of gender inequities in relationships that may contribute to women's lower sexual desire, and tested whether gender-based attitudes moderated the association. In two pre-registered studies (N = 943; S1 dyadic-longitudinal, S2 individual cross-sectional), women, compared to men, reported doing more of the household labor and lower sexual desire. However, we did not find that doing more household labor was associated with lower sexual desire. Rather, for women, the association between household labor and sexual desire depended on women's endorsement of benevolent sexism (i.e. beliefs idealizing traditional gender roles). Across studies, the associations between unequal division of household labor and lower sexual desire emerged as strongest and most consistent for women lower in benevolent sexism (i.e. who hold more egalitarian gender beliefs; S1 trending, S2 significant). However, this association did not emerge for women higher in benevolent sexism (S2), and in some cases, they reported greater desire when doing more household labor (S1). These findings extended past work by highlighting (a) gender differences in the association between division of labor and sexual desire, (b) the moderating role of gender-based attitudes, and (c) how gendered patterns of behavior within relationships can uphold and reinforce broader gender inequities.

Greater homework adherence in cognitive behavioral therapy (CBT) is associated with positive treatment outcomes. However, the problems emerging from CBT homework use are common and affect adherence. In recent years, gamification has been explored to increase intervention adherence, but not yet in relation specifically to homework assignments. In this study, the aim was to gain a better understanding of obstacles to CBT homework and the use of gamification to overcome these. Concept mapping, a method to organize related information visually, was used in this study. For the 1-day face-to-face concept mapping session, 7 therapists (32 to 55 y, 6 females) participated and generated items based on 2 focal questions of interest. The generated items were grouped on perceived similarity, and each individual item was rated on (1) severity and difficulty (focal question 1) and (2) importance, acceptance by therapist, and acceptance by patient (focal question 2). The item groups on perceived similarity were inserted into computer software. Based on multidimensional scaling and hierarchical cluster analyses, item clusters were generated by the computer software and were presented to the therapists. The therapists were asked for their preference for the number of items a cluster should contain. Through brainstorming, the therapists collectively generated a list of 29 possible reasons for not doing homework by patients. In the same manner, a list of 38 game design elements that could help patients make CBT homework was generated. External factors (eg, no time due to crisis situations) and lack of motivation (eg, not aspiring to a therapy goal) were perceived as the most important reasons for patients not to do homework. External and symptoms-unrelated internal factors were considered by therapists as the most difficult for patients to change for improved homework adherence. The game design elements, facilitation, and rewards were rated as most important to help patients do homework. These elements were also seen as most accepted by therapists. Facilitation of doing homework and rewards seem to have the potential to tackle some of the external factors and lack of motivation to make CBT homework that patients could have. Conclusions were limited by the small number of participating therapists. Future research is needed on the effects of specific game design elements, the number of these elements, their combinations, and patients' preferences.

For evaluation of predictive factors of sponataneous conception after saline infused sonosalpingography (SIS). A prospective study was conducted from August 2023 to December 2024 at reproductive medial unit at Mosul/Iraq. 100 women were recruited and categorized in to two groups: pregnant after SIS and non pregnant after SIS , for achievement of conception, the two groups were followed for 6 months duration and their clinical characteristics were compared . The group where polycystic ovary syndrome (PCOS) positive ladies were included show the duration of infertility for positive pregnancy test ladies was ≤ 2 years in 58% versus 42% > 2 years (p=0.0001),the history of cesarean section(CS) shows significant difference between pregnant and non pregnant (p=0.11). time to get pregnant after Saline -enhanced sonography shows 79% ≤ 2 months versus 21% > 2 months. the PCOS variable shows significant difference between pregnant women and non (p=0.037),the incidence of pregnancy was 24% markedly higher in first 2 months after doing the SIS equal to 79% , anti-mullerian hormone( AMH) didn’t show significant difference While in the group where PCOS positive ladies were excluded show the duration of infertility for pregnant ladies was ≤ 2 years in 66.7% versus 33.3% > 2 years (p=0.001),the history of CS shows considerable difference between pregnant and non pregnant (p=0.034). time neded to get pregnant after SIS shows 60% ≤ 2 months versus 40% > 2 months.,the pregnancy rate was 21.1% and notably higher in first 2 months after excuting hydrosalpingography equall to 60% ,AMH show significant difference in pregnant was 1.5ng/ml versus 1.2 in non Conclusion: The current study declare that SIS has positive effect on spontaneous conception this is must true in first two months after doing the SIS and it encourage considering expectant management for ladies with briefer duration of infertility, good ovarian capacity and less pelvic operation history.

Gaslighting is a form of psychological manipulation that causes a victim to doubt their sense of reality, usually leading to a loss of agency and emotional and mental instability. The phenomenon was identified over 50 years ago and discourse on the topic was largely confined to psychiatry; however, interest in gaslighting has experienced a resurgence with expansion both in terms of the contexts in which gaslighting is thought to occur as well as disciplines weighing in on the topic. The aim of this article is to offer a historical review of work on gaslighting that tracks how the term has evolved and to identify core features of the phenomena. In doing so we identify points of consensus and tension in the literature. We also differentiate gaslighting from related constructs and conclude by making specific recommendations for the future of scholarship on gaslighting, aligning these proposals with clinical strategies to mitigate its psychological impact in therapeutic practice.

The Arctic is a hotspot of environmental change, as demonstrated by various monitoring programs and studies north of the Polar Circle. As these activities primarily focus on detecting shifts in biodiversity and phenology, the functional dynamics of the terrestrial ecological community of Arctic systems remain comparatively understudied. Current research coverage of actual species interactions exhibits considerable temporal and spatial heterogeneity. Nevertheless, there have been numerous attempts to synthesize existing knowledge into conceptual frameworks, including for well-studied regions such as Svalbard. However, these schemes often do not incorporate the idea of interaction strength. In this work, we aim to integrate existing knowledge on interaction strengths into a conceptual model of the Svalbard Ecological Network. In doing so, we also highlight current knowledge gaps and the challenges of establishing a robust baseline of species interactions in the region. Such current challenges cannot be overcome without coordinated efforts among multiple research groups.

Many one-month alcohol-free challenges (AFCs) have been established to encourage and support lower alcohol intake. Completion of AFCs is known to be influenced by characteristics of individuals. This study explored the relative importance of individual characteristics compared to use of support provided by the AFC, and social factors including interactions with drinkers. We conducted a prospective study with a one-month follow-up. The link to the online survey was sent to people who registered for 'the Dry January® challenge'. Baseline data were provided by 634 adults, of whom 410 (65%) completed the follow-up. The follow-up questionnaire assessed completion and collected qualitative data on suggested improvements to support for participants. In multivariate analysis, completing the AFC was predicted by: greater drink refusal self-efficacy; planning to stop drinking after the AFC; not living with other drinkers; and doing the AFC with others. In qualitative analysis, many suggestions for improving support for participants focused on the social impacts of AFC participation. A novel contribution made by this study was identifying the importance of the social contexts in which individuals undertake AFCs. Organisers of AFCs should be aware of the influence of both individual and social factors, and tailor support accordingly.

Bone is a highly dynamic and purposefully organized structure that remodels constantly throughout adult life. Disordered bone remodeling, in which resorption of old bone by osteoclasts exceeds new bone formation by osteoblasts, results in bone loss, which, in turn, is associated with debilitating conditions, including osteoporosis and metastatic bone disease. The past decade has revealed vital new insights into the role of the central nervous system in skeletal regulation. These studies have led to a better understanding of physiologic circuitry, enabled us to revisit disease pathophysiology, and in doing so, prompted the creation of candidate therapeutics. The central neural control of bone is exerted through two arms - an amplitude-modulated (AM) neurohormonal arm that relies on changes in circulating levels of anterior and posterior pituitary hormones, which act on bone directly, and a frequency-modulated (FM) arm that arises from changes in the firing frequency of sympathetic, parasympathetic, and sensory nerves that innervate bone. Here, we review the medical consequences arising from the dysfunction of the AM and FM arms, as well as studies that have unmasked promising therapeutic targets.

TFE3 rearranged Renal cell carcinoma is a newly recognized entity with few reported cases. TFE3 positivity has poor prognosis and requires long term follow up. A 26-year-old woman presented with flank pain since 5 months. CECT revealed an exophytic mass abutting adjacent structures with no infiltration. Radical nephrectomy was done, showing a pale yellow tumour, replacing the kidney. Microscopically the tumour was disposed in papillae composed of clear cells with voluminous cytoplasm. Patient is doing well at 16 months' post-surgery. More studies on the morphology, immunohistochemistry with genetic correlation are needed to determine clinical behaviour, management and prognosis.

Commercial determinants of health, including tobacco, alcohol, ultra-processed foods, and fossil fuels, are among the leading drivers of preventable morbidity and mortality worldwide. Nursing education has traditionally emphasized individual behavioral risk factors, often neglecting structural and corporate influences on health. This article explores strategies to integrate these determinants into nursing curricula, highlighting the relevance of standardized nursing languages as pedagogical tools to foster critical awareness and advocacy skills among students. Narrative, pedagogical analysis drawing on public health scholarship, nursing taxonomies, and transformative education frameworks. Linking commercial determinants to nursing diagnoses such as Ineffective Health Management (00078) and Risk for Impaired Control of Health Behaviors (00246), interventions including Health Education (5510) and Addiction Management (4490), and outcomes such as Health Beliefs: Risk Control (1704) and Community Health Status (2808) provides a structured, evidence-based framework for critically analysing health inequities. Integrating commercial determinants into nursing education equips students with competencies not only in clinical care but also in advocacy, ethical reasoning, and public health leadership. This approach aligns with global calls for transformative education and positions nursing as a critical discipline in confronting structural drivers of disease. Educators should systematically incorporate commercial determinants into curricula using standardized nursing languages as frameworks for critical pedagogy. Doing so enhances students' ability to understand and address health beyond the individual level, preparing nurses to engage in policy, advocacy, and structural transformation.

The right of patients to decline information about their health, prognosis, and available treatment options is a salient principle in both domestic law and international declarations and conventions. This right may be considered either unnegotiable or subject to certain terms and conditions. While respecting this right may seem straightforward, doing so in clinical practice can be challenging. This article uses a realistic hypothetical scenario to examine the epistemic, moral, and practical challenges that can arise, particularly with patients nearing the end of life. These challenges include how and when to honor the right and its potential conflict with moral values such as self-determination, authenticity, and avoiding harm to oneself and others. The end of life exacerbates these issues because of the irretrievability of decisions and the successive reduction of possible courses of action, as well as potentially changing preferences. These potential conflicts of values deserve further attention and must be considered when deciding whether to honor a patient's wish not to know.

Effective translation relies on high performance teams integrating diverse disciplines to bring new drugs, medical devices, diagnostics or behavioral interventions into improved health. Despite substantial advancements informed by the Science of Team Science (SciTS), challenges remain in effective translational team (TT) operations, while limited institutional, scholarly, and practitioner legitimacy of team science expertise constrains efforts to address them. Here, we describe an essential member of the TT, the Team Science Professional (TSP). Serving as a team educator and facilitator of team interventions, the TSP plays a pivotal role in facilitating effective team performance. Current challenges faced by this nascent profession are defining career pathways and establishing competencies needed for expert performance. To address these challenges, the authors, representing a spectrum of academic universities organized as a special interest group (SIG) of the Association of Clinical and Translational Science (ACTS), propose a suite of individualized, standardized and pathway-selective micro-credentials (digital badges). Digital badges in "Team Science (TS) Fundamentals," "TS Practitioner," "TT Trainer" and "TT Intervention Expert" are described, along with preliminary feasibility and usability evaluations of the submission process. These stackable credentials provide a customizable, portable recognition of skills and help advance career pathways for TSPs. In so doing, the Digital Badge Initiative will enhance the capacity of translational science "Hubs" such as those supported by Clinical and Translational Science Awards to conduct effective and rigorous translation. Moving forward, the ACTS TSP SIG will be examining the impact of digital badging on standardization and its effect on career recognition and retention.

This Perspective explores and calls for the integration of Indigenous knowledge systems within sustainability science to address urgent environmental, social, and economic challenges. Insights emerged from a collaborative workshop held in Baawaating (Algoma District, Ontario, Canada) with knowledge holders, practitioners, scholars, and community leaders, including members from the Ketegaunseebee (Garden River) and Batchewana First Nations. The paper examines how Indigenous ways of being, thinking, and knowing can enrich sustainability research. This work focuses on mapping parallels and distinctions between Indigenous and other sustainability practices with regard to the planet, the land, and relationships. It explores systems thinking, circularity, and Two-Eyed Seeing as a way to reimagine human-land relationships through place-based knowledge and stewardship. We stress the importance of embedding purpose and intention in scientific inquiry and propose examples such as ceremonial practices, seven-generational thinking, and relational accountability. The Perspective calls for a paradigm shift beyond Western-centric and reductionist approaches, which lead to endless economic growth, toward holistic, interconnected, and intentional frameworks that respect Indigenous worldviews. A series of concrete calls to action urge sustainability researchers to integrate Indigenous knowledge respectfully, foster long-term collaborative relationships, and adopt regenerative and relational approaches in their scholarship. This will contribute to restoring the balance needed among cultures and between humanity and the natural world. Collectively, as sustainability scholars, we want to see meaningful change and encourage a paradigm shift: to embrace inclusive, holistic approaches that contribute to impactful, results-oriented actions that restore health to our world. You can do this through being advocates for change to promote reconciliation, strengthen intercultural relationships, and support greater well-being for all, and, in doing so, protect the planet by reducing ecological harm.

Non-autistic individuals find it difficult to read the behaviour of autistic people in comparison to non-autistic others. We investigated whether non-autistic people's ability to read autistic individuals is improved by providing diagnostic information, and whether this ability is associated with a person's knowledge about autism, prior contact with autistic people, and autism stigma. Participants (N = 128) viewed videos that were taken from a previous study. These showed autistic and non-autistic individuals reacting to events enacted by the researcher, and participants were asked to infer what event had taken place. Videos were presented either with no diagnostic information, a correct diagnostic label, or an incorrect label (autistic individuals labelled as non-autistic and vice versa). Autism knowledge, contact with autistic people, and autism stigma were measured by questionnaires. Participants performed less well for videos of autistic than non-autistic others. Diagnostic information had little impact on performance, although labelling non-autistic individuals as autistic reduced accuracy. Autism knowledge, contact with autistic people, and autism stigma were not associated with relative strength in interpreting the behaviour of autistic individuals. We conclude it might be difficult to train people to read autistic people's non-verbal behaviour more effectively; instead, intervention might focus on raising awareness of this issue.Lay AbstractRecent research has shown that non-autistic people are prone to misinterpreting the behaviour of autistic individuals, which may contribute to the difficulties autistic people often experience during social interactions. This suggests that interventions should identify ways to improve other people's ability to interpret autistic people's behaviour. However, little is known about what circumstances may improve non-autistic people's ability to read autistic others. This study investigated whether telling people that someone is autistic would improve their ability to interpret the behaviour of that person. We also investigated whether having more knowledge about autism, having previous contact with autistic people, or holding stigmatic attitudes about autism relates to this ability. The researchers used video clips that were recorded for a previous study. They showed autistic and non-autistic people reacting to aspects of the researchers' behaviour, such as being told a joke or paid a compliment. Participants' task was to watch the video clips and infer what the person in each video was reacting to and accuracy in doing so was recorded. The videos were presented with either no diagnostic information or with a diagnostic label alongside the video, which was either correct or inaccurate (labelling autistic individuals as non-autistic and vice versa). We used questionnaires to assess participants' autism knowledge, previous contact with autistic people, and autism stigma. We found that participants had more difficulty judging the reactions of autistic individuals than the non-autistic individuals. Telling participants that a person was autistic did not make people better at interpreting their behaviour, although labelling non-autistic participants as autistic reduced accuracy. Knowledge about autism, previous contact with autistic people, and autism stigma did not relate to a person's ability to interpret autistic people's behaviour. This suggests that it may not be easy to create interventions to improve people's ability to interpret the behaviour of autistic others. Intervention might focus on raising awareness of the need to avoid making assumptions based on the non-verbal behaviour of autistic people.

Cancer treatment is often described in biomedical language, while its emotional textures remain less visible. Experiences such as waiting, bodily changes, fatigue, uncertainty, and the quiet grief of chemotherapy shape how illness is lived beyond clinical procedures. This manuscript offers a poetic reflection on the emotional life of chemotherapy, focusing on how art may help name, hold, and witness what treatment cannot fully explain. Through poetic imagery centered on infusion rooms, changing bodies, and the altered temporality of treatment, the manuscript explores chemotherapy not only as medical intervention but also as an emotional condition marked by fear, endurance, vulnerability, and dignity. Art is positioned as a companion to illness, offering line, color, and language as forms of presence rather than a cure. This manuscript contributes to art and health discussions by foregrounding the lived and affective dimensions of cancer care. It highlights the value of artistic expression as a humane space where patients may remain more than just diagnosis, regimen, or symptoms. In doing so, it emphasizes that the role of art in healthcare lies not only in therapeutic support but also in sustaining dignity, recognition, and emotional visibility during treatment.