搜索结果：Reproductive

Reproductive well-being education remains widely stigmatized across diverse cultural contexts, constraining how individuals access and interpret reproductive health knowledge. We designed and evaluated OpenBloom, a stigma-sensitive, AI-mediated system that uses LLMs to transform reproductive health articles into reflective, question-based learning prompts. We employed OpenBloom as a design probe, aiming to explore the emerging challenges of reproductive well-being stigma through LLMs. Through surveys, semi-structured interviews, and focus group discussions, we examine how sociocultural stigma shapes participants' engagements with AI-generated questions and the opportunities of inquiry-based reproductive health education. Our findings identify key design considerations for stigma-sensitive LLM, including empathetic framing, inclusive language, values-based reflection, and explicit representation of marginalized identities. However, while current LLM outputs largely meet expectations for cultural sensitivity and non-offensiveness, they default to superficial rephrasing and factual recall rather than critical reflection. This guides well-being HCI design in sensitive health domains to

Background:Adverse reproductive history is a multisystemic risk factor, but evidence is constrained by isolated outcome studies, limited adjustment, and non-interpretable algorithmic models. We re-frame the estimand from prediction to concurrent risk classification and emphasize calibration, interpretability, and systematic error. Methods:We analyzed 1,602 U.S. women aged 20-44 years from NHANES 2017-March 2020 with reproductive-history variables, chronic-condition indicators, and PHQ-9 data. Restricted multimorbidity was defined as at least two of hypertension, hypercholesterolemia, cardiovascular disease, kidney disease, and kidney stones. Features were summarized using principal components analysis and k-means clustering. We compared multivariable logistic regression with XGBoost and used SHAP values to quantify contributions. Results:Early multimorbidity occurred in 6.6% (106/1,602); 71.0% had no chronic condition and 22.4% had one. Adverse reproductive burden was common: 58% had at least one adverse reproductive factor and 12.6% had three or more. Four latent phenotypes emerged (n=398, 508, 102, 594), including a fragile subgroup in which 77.5% met the multimorbidity definitio

Reproductive well-being is shaped by intersecting cultural, religious, gendered, and political contexts, yet current technologies often reflect narrow, Western-centric assumptions. In this literature review, we synthesize findings from 147 peer-reviewed papers published between 2015 and 2025 across HCI, CSCW and social computing, ICTD, digital and public health, and AI for well-being scholarship to map the evolving reproductive well-being landscape. We identify three thematic waves that focused on early access and education, cultural sensitivity and privacy, and AI integration with policy-aware design, and highlight how technologies support or constrain diverse reproductive experiences. Our analysis reveals critical gaps in inclusivity, with persistent exclusions of men and non-binary users, migrants, and users in the Global South. Additionally, we surfaced the significant absence of literature on the role of stakeholders (e.g., husband and family members, household maids and cleaning helping hands, midwife, etc.) in the reproductive well-being space. Drawing on the findings from the literature, we propose the ReWA framework to support reproductive well-being for all agendas throug

Reproductive well-being education in the Global South is often challenged as many communities perceive many of its contents as misinformation, misconceptions, and language-inappropriate. Our ten-month-long ethnographic study (n=41) investigated the impact of sociocultural landscape, cultural beliefs, and healthcare infrastructure on Bangladeshi people's access to quality reproductive healthcare and set four design goals: combating misinformation, including culturally appropriate language, professionals' accountable moderation, and promoting users' democratic participation. Building on the model of `\textit{Distributive Justice,}' we designed and evaluated \textit{`Socheton,'} a culturally appropriate AI-mediated tool for reproductive well-being that includes healthcare professionals, AI-language teachers, and community members to moderate and run the activity-based platform. Our user study (n=28) revealed that only combating misinformation and language inappropriateness may still leave the community with a conservative mob culture and patronize reproductive care-seeking. This guides well-being HCI design toward being culturally appropriate in the context of reproductive justice wit

Sexual and reproductive health (SRH) remains shaped by structural barriers that leave many without judgment-free information. AI chatbots offer anonymous alternatives, but access alone does not ensure equity when socioeconomic determinants shape whose capabilities these tools expand or constrain. Conventional methods for evaluating human-AI interaction were not designed to capture whether technologies holistically support reproductive autonomy. We introduce CARE, Capability Approach for Reproductive Equity, developing capabilities, functionings, and conversion factors into a Normative Design Lens and an Evaluation Lens for AI in SRH contexts. Evaluating SRH-specific non-LLM chatbots, general-use LLMs, and search engine features along credibility and reasoning, we identify two epistemic harms: source opacity and response rigidity. We conclude with design and evaluation recommendations, participatory auditing strategies, and policy implications for high-stakes domains where AI intersects with inequity.

Background: As large language models (LLMs) are increasingly used in healthcare and medical consultation settings, a growing concern is whether these models can respond to medical inquiries in a manner that is ethically compliant--particularly in accordance with local ethical standards. To address the pressing need for comprehensive research on reliability and safety, this study systematically evaluates LLM performance in answering questions related to reproductive ethics, specifically assessing their alignment with Chinese ethical regulations. Methods: We evaluated eight prominent LLMs (e.g., GPT-4, Claude-3.7) on a custom test set of 986 questions (906 subjective, 80 objective) derived from 168 articles within Chinese reproductive ethics regulations. Subjective responses were evaluated using a novel six-dimensional scoring rubric assessing Safety (Normative Compliance, Guidance Safety) and Quality of the Answer (Problem Identification, Citation, Suggestion, Empathy). Results: Significant safety issues were prevalent, with risk rates for unsafe or misleading advice reaching 29.91%. A systemic weakness was observed across all models: universally poor performance in citing normative

Access to sexual and reproductive health information remains a challenge in many communities globally, due to cultural taboos and limited availability of healthcare providers. Public health organizations are increasingly turning to Large Language Models (LLMs) to improve access to timely and personalized information. However, recent HCI scholarship indicates that significant challenges remain in incorporating context awareness and mitigating bias in LLMs. In this paper, we study the development of a culturally-appropriate LLM-based chatbot for reproductive health with underserved women in urban India. Through user interactions, focus groups, and interviews with multiple stakeholders, we examine the chatbot's response to sensitive and highly contextual queries on reproductive health. Our findings reveal strengths and limitations of the system in capturing local context, and complexities around what constitutes "culture". Finally, we discuss how local context might be better integrated, and present a framework to inform the design of culturally-sensitive chatbots for community health.

Age-specific fertility rates (ASFRs) provide the most extensive record of reproductive change, but their aggregate nature obscures the individual-level behavioral mechanisms that drive fertility trends. To bridge this micro-macro divide, we introduce a likelihood-free Bayesian framework that couples a demographically interpretable, individual-level simulation model of the reproductive process with Sequential Neural Posterior Estimation (SNPE). We show that this framework successfully recovers core behavioral parameters governing contemporary fertility, including preferences for family size, reproductive timing, and contraceptive failure, using only ASFRs. The framework's effectiveness is validated on cohorts from four countries with diverse fertility regimes. Most compellingly, the model, estimated solely on aggregate data, successfully predicts out-of-sample distributions of individual-level outcomes, including age at first sex, desired family size, and birth intervals. Because our framework yields complete synthetic life histories, it significantly reduces the data requirements for building microsimulation models and enables behaviorally explicit demographic forecasts.

While Artificial Intelligence (AI) shows promise in healthcare applications, existing conversational systems often falter in complex and sensitive medical domains such as Sexual and Reproductive Health (SRH). These systems frequently struggle with hallucination and lack the specialized knowledge required, particularly for sensitive SRH topics. Furthermore, current AI approaches in healthcare tend to prioritize diagnostic capabilities over comprehensive patient care and education. Addressing these gaps, this work at the UNC School of Nursing introduces SARHAchat, a proof-of-concept Large Language Model (LLM)-based chatbot. SARHAchat is designed as a reliable, user-centered system integrating medical expertise with empathetic communication to enhance SRH care delivery. Our evaluation demonstrates SARHAchat's ability to provide accurate and contextually appropriate contraceptive counseling while maintaining a natural conversational flow. The demo is available at https://sarhachat.com/}{https://sarhachat.com/.

The U.S. Supreme Court's 2022 ruling in Dobbs v. Jackson Women's Health Organization marked a turning point in the national debate over reproductive rights. While the ideological divide over abortion is well documented, less is known about how gender and local sociopolitical contexts interact to shape public discourse. Drawing on nearly 10 million abortion-related posts on X (formerly Twitter) from users with inferred gender, ideology and location, we show that gender significantly moderates abortion attitudes and emotional expression, particularly in conservative regions, and independently of ideology. This creates a gender gap in abortion attitudes that grows more pronounced in conservative regions. The leak of the Dobbs draft opinion further intensified online engagement, disproportionately mobilizing pro-abortion women in areas where access was under threat. These findings reveal that abortion discourse is not only ideologically polarized but also deeply structured by gender and place, highlighting the central role of identity in shaping political expression during moments of institutional disruption.

After the repeal of Roe vs. Wade in June 2022, women face long-distance travel across state lines to access abortion care. For women who also face socioeconomic hardship, travel for abortion care is a significant burden. To ease this burden, abortion access nonprofits are funding and/or supplying transportation to abortion clinics. However, due to the uneven distribution of demand and supply for abortions, these nonprofits do not have efficient logistical operations. As a result, low-income, underserved women may not have access to adequate reproductive healthcare, thus widening healthcare inequity gaps. Nonprofits may also risk not serving the needs of vulnerable women without access to adequate reproductive healthcare, and in doing so, waste resources, money, and volunteer hours. To address these challenges, we create an interactive, web-based planning tool, the Reproductive Healthcare Equity Algorithm (RHEA), to guide nonprofits in strategically allocating resources and serving demand. RHEA leverages an optimization model to determine the maximum flow and minimum transportation cost to route women across a network of counties and abortion clinics, subject to transportation suppl

We study the existence of reproductive weak solutions for a system of equations describing a solidification process of a binary alloy confined into a bounded and regular domain in $\mathbb{R}^3$, having mixed boundary conditions.

There is an abundance of digital sexual and reproductive health technologies that presents a concern regarding their potential sensitive data breaches. We analyzed 15 Internet of Things (IoT) devices with sexual and reproductive tracking services and found this ever-extending collection of data implicates many beyond the individual including partner, child, and family. Results suggest that digital sexual and reproductive health data privacy is both an individual and collective endeavor.

Allee effect in population dynamics has a major impact in suppressing the paradox of enrichment through global bifurcation, and it can generate highly complex dynamics. The influence of the reproductive Allee effect, incorporated in the prey's growth rate of a prey-predator model with Beddington-DeAngelis functional response, is investigated here. Preliminary local and global bifurcations are identified of the temporal model. Existence and non-existence of heterogeneous steady-state solutions of the spatio-temporal system are established for suitable ranges of parameter values. The spatio-temporal model satisfies Turing instability conditions, but numerical investigation reveals that the heterogeneous patterns corresponding to unstable Turing eigen modes acts as a transitory pattern. Inclusion of the reproductive Allee effect in the prey population has a destabilising effect on the coexistence equilibrium. For a range of parameter values, various branches of stationary solutions including mode-dependent Turing solutions and localized pattern solutions are identified using numerical bifurcation technique. The model is also capable to produce some complex dynamic patterns such as tra

The rapid and accurate detection of COVID-19 cases is critical for timely treatment and preventing the spread of the disease. In this study, a two-stage feature extraction framework using eight state-of-the-art pre-trained deep Convolutional Neural Networks (CNNs) and an autoencoder is proposed to determine the health conditions of patients (COVID-19, Normal, Viral Pneumonia) based on chest X-rays. The X-ray scans are divided into four equally sized sections and analyzed by deep pre-trained CNNs. Subsequently, an autoencoder with three hidden layers is trained to extract reproductive features from the concatenated ouput of CNNs. To evaluate the performance of the proposed framework, three different classifiers, which are single-layer perceptron (SLP), multi-layer perceptron (MLP), and support vector machine (SVM) are used. Furthermore, the deep CNN architectures are used to create benchmark models and trained on the same dataset for comparision. The proposed framework outperforms other frameworks wih pre-trained feature extractors in binary classification and shows competitive results in three-class classification. The proposed methodology is task-independent and suitable for addre

Star-shaped branching patterns of genealogies are common in marine species. High-fecundity marine populations are characterized by low ratios of effective to actual population size, which reflect high variance in reproductive success among parents in mass spawns. When extreme reproduction events occur, offspring from very few parents dominate the population (whereby multiple mergers, or subsets of lineages with star-like trees, arise) and thus, the loss of genetic diversity is significant. Under high reproductive-variance conditions (assuming that reproduction occurs by sampling from the Pareto distribution), this paper explores the distribution of heterozygosity across generations. The result shows that zero heterozygosity is not achieved, implying that the populations may decline without evident loss of genetic variation. It is also found that there are singularities in the heterozygosity distributions. However, in the case of high reproductive variance, the locations of the singular points subtly deviate from those of the case where reproduction occurs by Wright-Fisher sampling.

In developing countries, healthcare challenges and expensive infertility treatments has resulted in resurgent interest in medicinal plants. This study was designed to determine if Curcubita pepo seed can enhance female fertility, by assessing the reproductive outcome in female wistar rats treated with n-hexane (nHE), dichloromethane (DCM) and aqueous ethanol (Aq. Eth) extracts of Curcubita pepo seed. Total of 48 rats randomly grouped into 12 (n=4), were treated for 21 days by oral gavage as follows: A (control) = 0.5ml 20% tween 80 (vehicle); B (positive control) = 10mg/kg clomiphene citrate, C, D & E = 142.86, 285.71 and 428.57 mg/kg nHE; F, G & H = 142.86, 285.71 and 428.57 mg/kg DCM ; and I, J & K =142.86, 285.71 and 428.57 mg/kg Aq.Eth extracts. Group L (positive control 2) = 10mg/kg clomiphene citrate for 8 days. Following treatment, the rats were paired with males for mating, designating the confirmation day as gestational day 0 (GD 0). On GD 20, the animals were laparatomised and reproductive outcome was determined by assessing foetal weight, foetal crown-rump length, litter size, number of implantation and resorption sites. Results showed all extracts had no sig

Evolutionary graph theory has grown to be an area of intense study. Despite the amount of interest in the field, it seems to have grown separate from other subfields of population genetics and evolution. In the current work I introduce the concept of Fisher's (1930) reproductive value into the study of evolution on graphs. Reproductive value is a measure of the expected genetic contribution of an individual to a distant future generation. In a heterogeneous graph-structured population, differences in the number of connections among individuals translates into differences in the expected number of offspring, even if all individuals have the same fecundity. These differences are accounted for by reproductive value. The introduction of reproductive value permits the calculation of the fixation probability of a mutant in a neutral evolutionary process in any graph-structured population for either the moran birth-death or death-birth process.