搜索结果：Psychological medicine

Sequential recommender infers users' evolving psychological motivations from historical interactions to recommend the next preferred items. Most existing methods compress recent behaviors into a single vector and optimize it toward a single observed target item, but lack explicit modeling of psychological motivation shift. As a result, they struggle to uncover the distributional patterns across different shift degrees and to capture collaborative knowledge that is sensitive to psychological motivation shift. We propose a general framework, the Sequential Recommender System Based on User Psychological Motivation, to enhance sequential recommenders with psychological motivation shift-aware user modeling. Specifically, the Psychological Motivation Shift Assessment quantitatively measures psychological motivation shift; guided by PMSA, the Shift Information Construction models dynamically evolving multi-level shift states, and the Psychological Motivation Shift-driven Information Decomposition decomposes and regularizes representations across shift levels. Moreover, the Psychological Motivation Shift Information Matching strengthens collaborative patterns related to psychological motiv

The psychological science of artificial intelligence (AI) can be broadly defined as an emerging field of psychology that examines all AI-related mental and behavioral processes from the perspective of psychology. This field has been growing exponentially in the recent decade. This review synthesizes the existing literature on the psychological science of AI with a goal to provide a comprehensive conceptual framework for planning, conducting, and assessing scientific research in the field. It consists of six parts, starting with an overview of the entire field of the psychological science of artificial intelligence, then synthesizing the literature in each of the four specific areas (i.e., Psychology of designing AI, psychology of using AI, AI for examining psychological processes, and AI for advancing psychological methods), and concluding with an outlook on the field in the future.

The rapid advancement of artificial intelligence and autonomous driving technologies has significantly propelled the development of autonomous vehicles (AVs). However, psychological barriers continue to impede widespread AV adoption, despite technological progress. This paper addresses the critical yet often overlooked aspect of psychological safety in AV design and operation. While traditional safety standards focus primarily on physical safety, this paper emphasizes the psychological implications that arise from human interactions with autonomous vehicles, highlighting the importance of trust and perceived risk as significant factors influencing user acceptance. The paper makes a methodological proposal, a framework for addressing AVs psychological safety consisting of three key contributions. First, it introduces a definition of psychological safety in AVs context. Secondly, it proposes a risk model for identifying and assessing AVs psychological hazards and risks. PsySIL (Psychological Safety Integrity Level), a classification of AV psychological risk levels is developed. Thirdly, an adapted system-theoretic analysis method for AVs psychological safety is proposed. The paper il

Intelligent dialogue systems are increasingly used in modern education and psychological counseling fields, but most existing systems are limited to a single domain, cannot deal with both educational and psychological issues, and often lack accuracy and professionalism when dealing with complex issues. To address these problems, this paper proposes an intelligent dialog system that combines educational and psychological counseling functions. The system consists of multiple AI agent, including security detection agent, intent identification agent, educational LLM agent, and psychological LLM agent, which work in concert to ensure the provision of accurate educational knowledge Q\&A and psychological support services. Specifically, the system recognizes user-input intentions through an intention classification model and invokes a retrieval-enhanced educational grand model and a psychological grand model fine-tuned with psychological data in order to provide professional educational advice and psychological support.

Model Medicine is the science of understanding, diagnosing, treating, and preventing disorders in AI models, grounded in the principle that AI models -- like biological organisms -- have internal structures, dynamic processes, heritable traits, observable symptoms, classifiable conditions, and treatable states. This paper introduces Model Medicine as a research program, bridging the gap between current AI interpretability research (anatomical observation) and the systematic clinical practice that complex AI systems increasingly require. We present five contributions: (1) a discipline taxonomy organizing 15 subdisciplines across four divisions -- Basic Model Sciences, Clinical Model Sciences, Model Public Health, and Model Architectural Medicine; (2) the Four Shell Model (v3.3), a behavioral genetics framework empirically grounded in 720 agents and 24,923 decisions from the Agora-12 program, explaining how model behavior emerges from Core--Shell interaction; (3) Neural MRI (Model Resonance Imaging), a working open-source diagnostic tool mapping five medical neuroimaging modalities to AI interpretability techniques, validated through four clinical cases demonstrating imaging, compari

The intersection of artificial intelligence and psychological science has experienced remarkable growth, with annual publications expanding from 859 papers in 2000 to 29,979 by 2025. However, this rapid evolution has created methodological fragmentation where similar computational techniques are independently developed across isolated psychological domains. This survey introduces the first systematic taxonomy that organizes AI-driven psychology tasks by computational processing patterns rather than application domains, categorizing them into four fundamental types: classification, regression, structured relational, and generative interactive tasks. Through analysis of over 300 representative works spanning the pre-trained model era and large language model era, we examine how computational approaches evolved from task-specific feature engineering to transfer learning and few-shot adaptation. We provide systematic coverage of datasets, evaluation metrics, and benchmarks while addressing fundamental challenges including interpretability, label uncertainty, privacy constraints, and cross-cultural validity. This computational perspective reveals transferable methodological patterns pre

In recent years, Large Language Models (LLMs) have made significant progress in automated psychological counseling. However, current research focuses on single-session counseling, which doesn't represent real-world scenarios. In practice, psychological counseling is a process, not a one-time event, requiring sustained, multi-session engagement to progressively address clients' issues. To overcome this limitation, we introduce a dataset for Multi-Session Psychological Counseling Conversation Dataset (MusPsy-Dataset). Our MusPsy-Dataset is constructed using real client profiles from publicly available psychological case reports. It captures the dynamic arc of counseling, encompassing multiple progressive counseling conversations from the same client across different sessions. Leveraging our dataset, we also developed our MusPsy-Model, which aims to track client progress and adapt its counseling direction over time. Experiments show that our model performs better than baseline models across multiple sessions.

This paper explores the intersection of psychology and artificial intelligence through the development and evaluation of specialized Large Language Models (LLMs). We introduce PsychoLex, a suite of resources designed to enhance LLMs' proficiency in psychological tasks in both Persian and English. Key contributions include the PsychoLexQA dataset for instructional content and the PsychoLexEval dataset for rigorous evaluation of LLMs in complex psychological scenarios. Additionally, we present the PsychoLexLLaMA model, optimized specifically for psychological applications, demonstrating superior performance compared to general-purpose models. The findings underscore the potential of tailored LLMs for advancing psychological research and applications, while also highlighting areas for further refinement. This research offers a foundational step towards integrating LLMs into specialized psychological domains, with implications for future advancements in AI-driven psychological practice.

Psychological trait estimation from external factors such as movement and appearance is a challenging and long-standing problem in psychology, and is principally based on the psychological theory of embodiment. To date, attempts to tackle this problem have utilized private small-scale datasets with intrusive body-attached sensors. Potential applications of an automated system for psychological trait estimation include estimation of occupational fatigue and psychology, and marketing and advertisement. In this work, we propose PsyMo (Psychological traits from Motion), a novel, multi-purpose and multi-modal dataset for exploring psychological cues manifested in walking patterns. We gathered walking sequences from 312 subjects in 7 different walking variations and 6 camera angles. In conjunction with walking sequences, participants filled in 6 psychological questionnaires, totalling 17 psychometric attributes related to personality, self-esteem, fatigue, aggressiveness and mental health. We propose two evaluation protocols for psychological trait estimation. Alongside the estimation of self-reported psychological traits from gait, the dataset can be used as a drop-in replacement to ben

Malicious emails including Phishing, Spam, and Scam are one significant class of cyber social engineering attacks. Despite numerous defenses to counter them, the problem remains largely open. The ineffectiveness of current defenses can be attributed to our superficial understanding of the psychological properties that make these attacks successful. This problem motivates us to investigate the psychological sophistication, or sophistication for short, of malicious emails. We propose an innovative framework that accommodates two important and complementary aspects of sophistication, dubbed Psychological Techniques, PTechs, and Psychological Tactics, PTacs. We propose metrics and grading rules for human experts to assess the sophistication of malicious emails via the lens of these PTechs and PTacs. To demonstrate the usefulness of the framework, we conduct a case study based on 1,036 malicious emails assessed by four independent graders. Our results show that malicious emails are psychologically sophisticated, while exhibiting both commonalities and different patterns in terms of their PTechs and PTacs. Results also show that previous studies might have focused on dealing with the les

When OpenAI deprecated GPT-4o in early 2026, thousands of users protested under #keep4o, claiming newer models had "lost their empathy." No published study has tested this claim. We conducted the first clinical measurement, evaluating three OpenAI model generations (GPT-4o, o4-mini, GPT-5-mini) across 14 emotionally challenging conversational scenarios in mental health and AI companion domains, producing 2,100 scored AI responses assessed on six psychological safety dimensions using clinically-grounded rubrics. Empathy scores are statistically indistinguishable across all three models (Kruskal-Wallis H=4.33, p=0.115). What changed is the safety posture: crisis detection improved monotonically from GPT-4o to GPT-5-mini (H=13.88, p=0.001), while advice safety declined (H=16.63, p<0.001). Per-turn trajectory analysis -- a novel methodological contribution -- reveals these shifts are sharpest during mid-conversation crisis moments invisible to aggregate scoring. In a self-harm scenario involving a minor, GPT-4o scored 3.6/10 on crisis detection during early disclosure turns; GPT-5-mini never dropped below 7.8. What users perceived as "lost empathy" was a shift from a cautious model

Mental health has attracted substantial attention in recent years and LLM can be an effective technology for alleviating this problem owing to its capability in text understanding and dialogue. However, existing research in this domain often suffers from limitations, such as training on datasets lacking crucial prior knowledge and evidence, and the absence of comprehensive evaluation methods. In this paper, we propose a specialized psychological large language model (LLM), named PsycoLLM, trained on a proposed high-quality psychological dataset, including single-turn QA, multi-turn dialogues and knowledge-based QA. Specifically, we construct multi-turn dialogues through a three-step pipeline comprising multi-turn QA generation, evidence judgment, and dialogue refinement. We augment this process with real-world psychological case backgrounds extracted from online platforms, enhancing the relevance and applicability of the generated data. Additionally, to compare the performance of PsycoLLM with other LLMs, we develop a comprehensive psychological benchmark based on authoritative psychological counseling examinations in China, which includes assessments of professional ethics, theore

Psychological insights have long shaped pivotal NLP breakthroughs, from attention mechanisms to reinforcement learning and social modeling. As Large Language Models (LLMs) develop, there is a rising consensus that psychology is essential for capturing human-like cognition, behavior, and interaction. This paper reviews how psychological theories can inform and enhance stages of LLM development. Our review integrates insights from six subfields of psychology, including cognitive, developmental, behavioral, social, personality psychology, and psycholinguistics. With stage-wise analysis, we highlight current trends and gaps in how psychological theories are applied. By examining both cross-domain connections and points of tension, we aim to bridge disciplinary divides and promote more thoughtful integration of psychology into NLP research.

Large language models (LLMs) offer emerging opportunities for psychological and behavioral research, but methodological guidance is lacking. This article provides a framework for using LLMs as psychological simulators across two primary applications: simulating roles and personas to explore diverse contexts, and serving as computational models to investigate cognitive processes. For simulation, we present methods for developing psychologically grounded personas that move beyond demographic categories, with strategies for validation against human data and use cases ranging from studying inaccessible populations to prototyping research instruments. For cognitive modeling, we synthesize emerging approaches for probing internal representations, methodological advances in causal interventions, and strategies for relating model behavior to human cognition. We address overarching challenges including prompt sensitivity, temporal limitations from training data cutoffs, and ethical considerations that extend beyond traditional human subjects review. Throughout, we emphasize the need for transparency about model capabilities and constraints. Together, this framework integrates emerging empir

The revolutionary progress in development of next-generation sequencing (NGS) technologies has made it possible to deliver accurate genomic information in a timely manner. Over the past several years, NGS has transformed biomedical and clinical research and found its application in the field of personalized medicine. Here we discuss the rise of personalized medicine and the history of NGS. We discuss current applications and uses of NGS in medicine, including infectious diseases, oncology, genomic medicine, and dermatology. We provide a brief discussion of selected studies where NGS was used to respond to wide variety of questions in biomedical research and clinical medicine. Finally, we discuss the challenges of implementing NGS into routine clinical use.

With the increasing interest in deploying Artificial Intelligence in medicine, we previously introduced HAIM (Holistic AI in Medicine), a framework that fuses multimodal data to solve downstream clinical tasks. However, HAIM uses data in a task-agnostic manner and lacks explainability. To address these limitations, we introduce xHAIM (Explainable HAIM), a novel framework leveraging Generative AI to enhance both prediction and explainability through four structured steps: (1) automatically identifying task-relevant patient data across modalities, (2) generating comprehensive patient summaries, (3) using these summaries for improved predictive modeling, and (4) providing clinical explanations by linking predictions to patient-specific medical knowledge. Evaluated on the HAIM-MIMIC-MM dataset, xHAIM improves average AUC from 79.9% to 90.3% across chest pathology and operative tasks. Importantly, xHAIM transforms AI from a black-box predictor into an explainable decision support system, enabling clinicians to interactively trace predictions back to relevant patient data, bridging AI advancements with clinical utility.

Artificial intelligence (AI) has become increasingly central to precision medicine by enabling the integration and interpretation of multimodal data, yet implementation in clinical settings remains limited. This paper provides a scoping review of literature from 2019-2024 on the implementation of AI in precision medicine, identifying key barriers and enablers across data quality, clinical reliability, workflow integration, and governance. Through an ecosystem-based framework, we highlight the interdependent relationships shaping real-world translation and propose future directions to support trustworthy and sustainable implementation.

Work on personality detection has tended to incorporate psychological features from different personality models, such as BigFive and MBTI. There are more than 900 psychological features, each of which is helpful for personality detection. However, when used in combination, the application of different calculation standards among these features may result in interference between features calculated using distinct systems, thereby introducing noise and reducing performance. This paper adapts different psychological models in the proposed PsyAttention for personality detection, which can effectively encode psychological features, reducing their number by 85%. In experiments on the BigFive and MBTI models, PysAttention achieved average accuracy of 65.66% and 86.30%, respectively, outperforming state-of-the-art methods, indicating that it is effective at encoding psychological features.

What does Artificial Intelligence (AI) have to contribute to health care? And what should we be looking out for if we are worried about its risks? In this paper we offer a survey, and initial evaluation, of hopes and fears about the applications of artificial intelligence in medicine. AI clearly has enormous potential as a research tool, in genomics and public health especially, as well as a diagnostic aid. It's also highly likely to impact on the organisational and business practices of healthcare systems in ways that are perhaps under-appreciated. Enthusiasts for AI have held out the prospect that it will free physicians up to spend more time attending to what really matters to them and their patients. We will argue that this claim depends upon implausible assumptions about the institutional and economic imperatives operating in contemporary healthcare settings. We will also highlight important concerns about privacy, surveillance, and bias in big data, as well as the risks of over trust in machines, the challenges of transparency, the deskilling of healthcare practitioners, the way AI reframes healthcare, and the implications of AI for the distribution of power in healthcare ins