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Wireless mouse rings offer subtle, reliable pointing interactions for wearable computing platforms, but the small battery below 27 mAh in the miniature rings restricts the ring's continuous lifespan to just 1-2 hours due to the power consumption of current low-powered wireless communication like BLE. However, the picoRing mouse addresses this by enabling continuous ring-based mouse interaction with ultra-low-powered ring-to-wristband wireless communication through a coil-based impedance sensing method called semi-passive inductive telemetry. This allows a wristband coil to capture a unique frequency response of a nearby ring coil via sensitive inductive coupling, converting the user's mouse input into the unique frequency response via an 820 uW mouse-driven modulation module. Thus, the continuous use of picoRing mouse can potentially last over 92 hours on a single charge of a 20 mAh battery while supporting subtle scrolling and pressing interactions.

As Extended Reality (XR) systems increasingly map and understand the physical world, interacting with these blended representations remains challenging. The current push for "natural" inputs has its trade-offs: touch is limited by human reach and fatigue, while gaze often lacks the precision for fine interaction. To bridge this gap, we introduce World Mouse, a cross-reality cursor that reinterprets the familiar 2D desktop mouse for complex 3D scenes. The system is driven by two core mechanisms: within-object interaction, which uses surface normals for precise cursor placement, and between-object navigation, which leverages interpolation to traverse empty space. Unlike previous virtual-only approaches, World Mouse leverages semantic segmentation and mesh reconstruction to treat physical objects as interactive surfaces. Through a series of prototypes, including object manipulation and screen-to-world transitions, we illustrate how cross-reality cursors may enable seamless interactions across real and virtual environments.

Mouse and human brains have different functions that depend on their neuronal networks. In this study, we analyzed nanometer-scale three-dimensional structures of brain tissues of the mouse medial prefrontal cortex and compared them with structures of the human anterior cingulate cortex. The obtained results indicated that mouse neuronal somata are smaller and neurites are thinner than those of human neurons. These structural features allow mouse neurons to be integrated in the limited space of the brain, though thin neurites should suppress distal connections according to cable theory. We implemented this mouse-mimetic constraint in convolutional layers of a generative adversarial network (GAN) and a denoising diffusion implicit model (DDIM), which were then subjected to image generation tasks using photo datasets of cat faces, cheese, human faces, and birds. The mouse-mimetic GAN outperformed a standard GAN in the image generation task using the cat faces and cheese photo datasets, but underperformed for human faces and birds. The mouse-mimetic DDIM gave similar results, suggesting that the nature of the datasets affected the results. Analyses of the four datasets indicated diffe

In human sleep staging models, augmenting the temporal context of the input to the range of tens of minutes has recently demonstrated performance improvement. In contrast, the temporal context of mouse sleep staging models is typically in the order of tens of seconds. While long-term time patterns are less clear in mouse sleep, increasing the temporal context further than that of the current mouse sleep staging models might still result in a performance increase, given that the current methods only model very short term patterns. In this study, we examine the influence of increasing the temporal context in mouse sleep staging up to 15 minutes in three mouse cohorts using two recent and high-performing human sleep staging models that account for long-term dependencies. These are compared to two prominent mouse sleep staging models that use a local context of 12 s and 20 s, respectively. An increase in context up to 28 s is observed to have a positive impact on sleep stage classification performance, especially in REM sleep. However, the impact is limited for longer context windows. One of the human sleep scoring models, L-SeqSleepNet, outperforms both mouse models in all cohorts. Th

Temporal Interference (TI) stimulation enables deep brain targeting, yet precise optimization tools for mouse models remain limited. We developed a computational optimization tool integrating mouse head modeling with the optimization algorithm to optimize stimulation strategies for predefined target regions. By balancing target intensity and spatial focality, the optimized strategy significantly outperformed empirical baselines. For the CA3-CA1 target, it achieved a 7-fold intensity increase (10.29 vs. 2.89 V/m) under iso-focality conditions. Conversely, for the Dentate Gyrus, it improved spatial confinement ($r_{0.5}$ reduced from 3.99 to 3.54 mm) while maintaining comparable intensity. Cross-model validation on a standardized Sim4Life phantom further confirmed the framework's robustness. This approach offers a powerful tool for enhancing the precision and reproducibility of preclinical TI stimulation studies.

Acoustic Side-Channel Attacks (ASCAs) extract sensitive information by using audio emitted from a computing devices and their peripherals. Attacks targeting keyboards are popular and have been explored in the literature. However, similar attacks targeting other human interface peripherals, such as computer mice, are under-explored. To this end, this paper considers security leakage via acoustic signals emanating from normal mouse usage. We first confirm feasibility of such attacks by showing a proof-of-concept attack that classifies four mouse movements with 97% accuracy in a controlled environment. We then evolve the attack towards discerning twelve unique mouse movements using a smartphone to record the experiment. Using Machine Learning (ML) techniques, the model is trained on an experiment with six participants to be generalizable and discern among twelve movements with 94% accuracy. In addition, we experiment with an attack that detects a user action of closing a full-screen window on a laptop. Achieving an accuracy of 91%, this experiment highlights exploiting audio leakage from computer mouse movements in a realistic scenario.

Visual robustness and neural alignment remain critical challenges in developing artificial agents that can match biological vision systems. We present the winning approaches from Team HCMUS_TheFangs for both tracks of the NeurIPS 2025 Mouse vs. AI: Robust Visual Foraging Competition. For Track 1 (Visual Robustness), we demonstrate that architectural simplicity combined with targeted components yields superior generalization, achieving 95.4% final score with a lightweight two-layer CNN enhanced by Gated Linear Units and observation normalization. For Track 2 (Neural Alignment), we develop a deep ResNet-like architecture with 16 convolutional layers and GLU-based gating that achieves top-1 neural prediction performance with 17.8 million parameters. Our systematic analysis of ten model checkpoints trained between 60K to 1.14M steps reveals that training duration exhibits a non-monotonic relationship with performance, with optimal results achieved around 200K steps. Through comprehensive ablation studies and failure case analysis, we provide insights into why simpler architectures excel at visual robustness while deeper models with increased capacity achieve better neural alignment. Ou

In the realm of computer security, the importance of efficient and reliable user authentication methods has become increasingly critical. This paper examines the potential of mouse movement dynamics as a consistent metric for continuous authentication. By analyzing user mouse movement patterns in two contrasting gaming scenarios, "Team Fortress" and Poly Bridge we investigate the distinctive behavioral patterns inherent in high-intensity and low-intensity UI interactions. The study extends beyond conventional methodologies by employing a range of machine learning models. These models are carefully selected to assess their effectiveness in capturing and interpreting the subtleties of user behavior as reflected in their mouse movements. This multifaceted approach allows for a more nuanced and comprehensive understanding of user interaction patterns. Our findings reveal that mouse movement dynamics can serve as a reliable indicator for continuous user authentication. The diverse machine learning models employed in this study demonstrate competent performance in user verification, marking an improvement over previous methods used in this field. This research contributes to the ongoing

We identify a particular mouse, $M^{\text{ld}}$, the minimal ladder mouse, that sits in the mouse order just past $M_n^{\sharp}$ for all $n$, and we show that $\mathbb{R}\cap M^{\text{ld}} = Q_{ω+1}$, the set of reals that are $Δ^1_{ω+1}$ in a countable ordinal. Thus $Q_{ω+1}$ is a mouse set. This is analogous to the fact that $\mathbb{R}\cap M^{\sharp}_1 = Q_3$ where $M^{\sharp}_1$ is the the sharp for the minimal inner model with a Woodin cardinal, and $Q_3$ is the set of reals that are $Δ^1_3$ in a countable ordinal. More generally $\mathbb{R}\cap M^{\sharp}_{2n+1} = Q_{2n+3}$. The mouse $M^{\text{ld}}$ and the set $Q_{ω+1}$ compose the next natural pair to consider in this series of results. Thus we are proving the mouse set theorem just past projective. Some of this is not new. $\mathbb{R}\cap M^{\text{ld}} \subseteq Q_{ω+1}$ was known in the 1990's. But $Q_{ω+1} \subseteq M^{\text{ld}}$ was open until Woodin found a proof in 2018. The main goal of this paper is to give Woodin's proof.

Biometrics is used to authenticate an individual based on physiological or behavioral traits. Mouse dynamics is an example of a behavioral biometric that can be used to perform continuous authentication as protection against security breaches. Recent research on mouse dynamics has shown promising results in identifying users; however, it has not yet reached an acceptable level of accuracy. In this paper, an empirical evaluation of different classification techniques is conducted on a mouse dynamics dataset, the Balabit Mouse Challenge dataset. User identification is carried out using three mouse actions: mouse move, point and click, and drag and drop. Verification and authentication methods are conducted using three machine-learning classifiers: the Decision Tree classifier, the K-Nearest Neighbors classifier, and the Random Forest classifier. The results show that the three classifiers can distinguish between a genuine user and an impostor with a relatively high degree of accuracy. In the verification mode, all the classifiers achieve a perfect accuracy of 100%. In authentication mode, all three classifiers achieved the highest accuracy (ACC) and Area Under Curve (AUC) from scenar

Quantitative MRI enables direct quantification of contrast agent concentrations in contrast-enhanced scans. However, the lengthy scan times required by conventional methods are inadequate for tracking contrast agent transport dynamically in mouse brain. We developed a 3D MR fingerprinting (MRF) method for simultaneous T1 and T2 mapping across the whole mouse brain with 4.3-min temporal resolution. We designed a 3D MRF sequence with variable acquisition segment lengths and magnetization preparations on a 9.4T preclinical MRI scanner. Model-based reconstruction approaches were employed to improve the accuracy and speed of MRF acquisition. The method's accuracy for T1 and T2 measurements was validated in vitro, while its repeatability of T1 and T2 measurements was evaluated in vivo (n=3). The utility of the 3D MRF sequence for dynamic tracking of intracisternally infused Gd-DTPA in the whole mouse brain was demonstrated (n=5). Phantom studies confirmed accurate T1 and T2 measurements by 3D MRF with an undersampling factor up to 48. Dynamic contrast-enhanced (DCE) MRF scans achieved a spatial resolution of 192 x 192 x 500 um3 and a temporal resolution of 4.3 min, allowing for the analy

The think aloud method is an important and commonly used tool for usability optimization. However, analyzing think aloud data could be time consuming. In this paper, we put forth an automatic analysis of verbal protocols and test the link between spoken feedback and the stimulus using eye tracking and mouse tracking. The gained data - user feedback linked to a specific area of the stimulus - could be used to let an expert review the feedback on specific web page elements or to visualize on which parts of the web page the feedback was given. Specifically, we test if participants fixate on or point with the mouse to the content of the webpage that they are verbalizing. During the testing, participants were shown three websites and asked to verbally give their opinion. The verbal responses, along with the eye and cursor movements were recorded. We compared the hit rate, defined as the percentage of verbally mentioned areas of interest (AOIs) that were fixated with gaze or pointed to with the mouse. The results revealed a significantly higher hit rate for the gaze compared to the mouse data. Further investigation revealed that, while the mouse was mostly used passively to scroll, the g

Moving from animal models to human applications in preclinical research encompasses a broad spectrum of disciplines in medical science. A fundamental element in the development of new drugs, treatments, diagnostic methods, and in deepening our understanding of disease processes is the accurate measurement of kidney tissues. Past studies have demonstrated the viability of translating glomeruli segmentation techniques from mouse models to human applications. Yet, these investigations tend to neglect the complexities involved in segmenting pathological glomeruli affected by different lesions. Such lesions present a wider range of morphological variations compared to healthy glomerular tissue, which are arguably more valuable than normal glomeruli in clinical practice. Furthermore, data on lesions from animal models can be more readily scaled up from disease models and whole kidney biopsies. This brings up a question: ``\textit{Can a pathological segmentation model trained on mouse models be effectively applied to human patients?}" To answer this question, we introduced GLAM, a deep learning study for fine-grained segmentation of human kidney lesions using a mouse model, addressing mou

We first study the suitability of behavioral biometrics to distinguish between computers and humans, commonly named as bot detection. We then present BeCAPTCHA-Mouse, a bot detector based on: i) a neuromotor model of mouse dynamics to obtain a novel feature set for the classification of human and bot samples; and ii) a learning framework involving real and synthetically generated mouse trajectories. We propose two new mouse trajectory synthesis methods for generating realistic data: a) a function-based method based on heuristic functions, and b) a data-driven method based on Generative Adversarial Networks (GANs) in which a Generator synthesizes human-like trajectories from a Gaussian noise input. Experiments are conducted on a new testbed also introduced here and available in GitHub: BeCAPTCHA-Mouse Benchmark; useful for research in bot detection and other mouse-based HCI applications. Our benchmark data consists of 15,000 mouse trajectories including real data from 58 users and bot data with various levels of realism. Our experiments show that BeCAPTCHA-Mouse is able to detect bot trajectories of high realism with 93% of accuracy in average using only one mouse trajectory. When o

Background: Linear mixed-effects models are central for analyzing longitudinal continuous data, yet many learners meet them as scattered formulas or software output rather than as a coherent workflow. There is a need for a single, reproducible case study that links questions, model building, diagnostics, and interpretation. Methods: We reanalyze a published mouse body-weight experiment with 31 mice in three groups weighed weekly for 12 weeks. After reshaping the data to long format and using profile plots to motivate linear time trends, we fit three random-intercept linear mixed models: a common-slope model, a fully interacted group-by-time model, and a parsimonious model with group-specific intercepts, a shared slope for two groups, and an extra slope for the third. Models are compared using maximum likelihood, AIC, BIC, and likelihood ratio tests, and linear contrasts are used to estimate group differences in weekly means and 12 week gains. Results: The parsimonious model fits as well as the fully interacted model and clearly outperforms the common-slope model, revealing small and similar gains in two groups and much steeper growth in the third, with highly significant contrasts

Unconscious behaviors are one of the indicators of the human perception process from a psychological perspective. As a result of perception responses, hand gestures show behavioral responses from given stimuli. Mouse usages in Human-Computer Interaction (HCI) show hand gestures that individuals perceive information processing. This paper presents an investigation of the correlation between unconscious mouse actions and human cognitive workload. We extracted mouse behaviors from a Robot Operating System (ROS) file-based dataset that user responses are reproducible. We analyzed redundant mouse movements to complete a dual $n$-back game by solely pressing the left and right buttons. Starting from a hypothesis that unconscious mouse behaviors predict different levels of cognitive loads, we statistically analyzed mouse movements. We also validated mouse behaviors with other modalities in the dataset, including self-questionnaire and eye blinking results. As a result, we found that mouse behaviors that occur unconsciously and human cognitive workload correlate.

This paper presents a new way of getting high-quality saliency maps for video, using a cheaper alternative to eye-tracking data. We designed a mouse-contingent video viewing system which simulates the viewers' peripheral vision based on the position of the mouse cursor. The system enables the use of mouse-tracking data recorded from an ordinary computer mouse as an alternative to real gaze fixations recorded by a more expensive eye-tracker. We developed a crowdsourcing system that enables the collection of such mouse-tracking data at large scale. Using the collected mouse-tracking data we showed that it can serve as an approximation of eye-tracking data. Moreover, trying to increase the efficiency of collected mouse-tracking data we proposed a novel deep neural network algorithm that improves the quality of mouse-tracking saliency maps.

Compared to other behavioural biometrics, mouse dynamics is a less explored area. General purpose data sets containing unrestricted mouse usage data are usually not available. The Balabit data set was released in 2016 for a data science competition, which against the few subjects, can be considered the first adequate publicly available one. This paper presents a performance evaluation study on this data set for impostor detection. The existence of very short test sessions makes this data set challenging. Raw data were segmented into mouse move, point and click and drag and drop types of mouse actions, then several features were extracted. In contrast to keystroke dynamics, mouse data is not sensitive, therefore it is possible to collect negative mouse dynamics data and to use two-class classifiers for impostor detection. Both action- and set of actions-based evaluations were performed. Set of actions-based evaluation achieves 0.92 AUC on the test part of the data set. However, the same type of evaluation conducted on the training part of the data set resulted in maximal AUC (1) using only 13 actions. Drag and drop mouse actions proved to be the best actions for impostor detection.

Background: Transposed elements (TEs) have a substantial impact on mammalian evolution and are involved in numerous genetic diseases. We compared the impact of TEs on the human transcriptome and the mouse transcriptome. Results: We compiled a dataset of all TEs in the human and mouse genomes, identifying 3,932,058 and 3,122,416 TEs, respectively. We than extracted TEs located within human and mouse genes and, surprisingly, we found that 60% of TEs in both human and mouse are located in intronic sequences, even though introns comprise only 24% of the human genome. All TE families in both human and mouse can exonize. TE families that are shared between human and mouse exhibit the same percentage of TE exonization in the two species, but the exonization level of Alu, a primatespecific retroelement, is significantly greater than that of other TEs within the human genome, leading to a higher level of TE exonization in human than in mouse (1,824 exons compared with 506 exons, respectively). We detected a primate-specific mechanism for intron gain, in which Alu insertion into an exon creates a new intron located in the 3' untranslated region (termed 'intronization'). Finally, the insertio