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To assess the sealing properties of the most commonly used materials for retrograde filling using a novel reproducible and standardized laboratory testing method. The study included 36 intact teeth divided into four experimental groups according to the type of filling material used (Dia-Root BioMTA, Biodentine, Trioxident, Ketac Cem) and two control groups consisting of intact teeth with cleaned and pulp-filled cavities. Sealing ability was evaluated through visual inspection and spectrophotometric analysis of dye penetration over a period of one month. No dye penetration through the retrograde filling was observed in any of the experimental groups, confirming the high sealing capacity of the materials. Changes in environmental pH from neutral to acidic did not significantly affect permeability. All tested materials demonstrated reliable sealing of the retrograde cavity, indicating their suitability for use in apical surgery. Оценка герметизационных свойств наиболее часто применяемых при ретроградном пломбировании материалов с помощью нового воспроизводимого и стандартизованного способа лабораторных испытаний. В исследование включено 36 интактных зубов, удаленных по ортодонтическим показаниям, разделенных на четыре экспериментальные группы по типу пломбировочного материала (Dia-Root BioMTA, Biodentine, Триоксидент, Ketac Cem) и две контрольные группы с интактными зубами с очищенной и заполненной пульпой полостью зуба. Герметичность оценивали с помощью визуального осмотра и спектрофотометрического анализа проникновения красителя в течение месяца. Исследование показало отсутствие проникновения красителя через ретроградную пломбу во всех экспериментальных группах, подтверждая высокую герметичность материалов. Изменение кислотности среды от нейтральной до кислой не оказывало значимого влияния на проницаемость. Все исследуемые материалы демонстрировали надежную герметизацию ретроградной полости, что свидетельствовало об их соответствии для применения в апикальной хирургии.
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Possible accumulation of benzpyrene in wheat grain during its drying by means of a heat-carrying agent (air diluted combustion products) containing this carcinogen was studied in a laboratory set-up. With benzpyrene contained in the heat-carrier in an amount of 0.12 gamma/m3 this carcinogen was amassing in the grain with all conditions and methods of drying under study. An increased benzpyrene content in the grain by comparison with the background one was noted under optimal conditions of drying in a solid layer, boiling layer and in a suspended state by as much as 23, 11 and 3 times respectively. On the basis of these and literature data a conclusion is drawn that grain may be dried in suspended state (recirculation dryers) under definite, parctically realizable conditions without accumulation of benzpyrene therein.
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Clinical efficacy and effect of cefuroxime, claforan and pentrexyl used endolymphatically were studied in 85 patients with acute abscess forming and persisting pneumonia. Previous routine antibiotic therapy in these patients was little effective. Administration of the antibiotics into the peripheral lymph nodes provided blocking of the lymphagenic pathway for the infection due to high levels in the lymphatic system. Endolymphatic use of cefuroxime and claforan resulted in a significant improvement of the functions of the T- and B-immunity systems and the indices of natural resistance. The levels of the autoimmune reactions and sensitization to the bacterial antigens decreased. Endolymphatic use of cefuroxime and claforan once every 3 days provided recovery of 9 2.8 per cent of the patients, the treatment periods being decreased 2.5--3 times. Intravenous administration of the drugs according to the routine schemes, endolymphatic use of pentrexyl (5 g once every 3 days) and endolymphatic administration of cefuroxime in a single dose followed by intravenous therapy was less effective. The efficacy of pentrexyl increased, when it was used endolymphatically in combination with lysozyme. Endolymphatic use of claforan in doses of 2--3 g once every 3 days (3--4 infusions during the treatment course) was most effective.
Diplen-Denta biopolymer adhesive film with chlorohexidine-was used in the treatment of periodontal inflammations of different severity. The efficacy of treatment of gingivitis and periodontitis is assessed from changes in the clinical parameters and in the activity of neutrophil elastase in the gingival liquid. The new treatment is highly effective in patients with catarrhal gingivitis and generalized periodontitis of light and medium severity.
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Various aspects of horizontal gene transfer among bacteria are considered: modeling of this phenomenon in microcosms and natural environments; influence of gene migration on the composition of natural bacterial populations; peculiarities of bacterial chromosome evolution.
Fifty-two patients with lichen planus were examined over the course of disease using clinical, microbiological, and histological methods. Treatment protocols aimed at normalization of microbiocenosis have been developed, based on the detected microbiological and histological changes.
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In 56 patients aged from 58 to 82 years with the III and IV degrees of risk operated upon for malignant tumors of organs of the thoracic and abdominal organs Solcoseryl was included in the complex of anesthesia measures. It was given intravenously or as inhalation in dosage of 1000 mg. It was found that using Solcoseryl considerably reduced the amount of postoperative complications in high risk patients. It led to lower level of lipid peroxidation and activation of the antioxidant system and thus may be considered as an important component of therapy at the intra- and postoperative periods.
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