Navigating the internet can be a multifaceted experience for LGBTQ+ individuals, with the potential to support or harm wellbeing. Online spaces offer access to supportive communities, which can provide a variety of benefits. However, online spaces can also expose LGBTQ+ internet users to anti-LGBTQ+ hate and harassment, in addition to exclusion and discrimination from LGBTQ+ communities themselves. However, the nuances of online dynamics and their effects on wellbeing remain underexplored, particularly through the lens of Social Identity Theory (SIT). The present study addresses the research gap through exploring the online experiences of LGBTQ+ adults, focusing on social interactions and group dynamics. Results from a qualitative survey of 136 participants identified complex inclusionary and exclusionary dynamics, strongly affecting participants' appraisal of their own identity, feelings toward LGBTQ+ others, and their sense of belonging both online and offline. While SIT offers considerable explanatory power for online experiences, the study identifies limitations in its overall applicability. The study's findings highlight the internet's dual role in nurturing and harming LGBTQ+ wellbeing and inclusion. This study furthers our insights into the complexities of online experiences and group dynamics of LGBTQ+ adults, highlighting both supportive and exclusionary behaviors prevalent throughout LGBTQ+ communities online. Additionally, the study provides an understanding into the nuances of LGBTQ+ online interactions with Social Identity Theory, including an assessment of the theory’s explanatory applicability and limitations.
This study compared LGBTQ individuals aged 50+ with and without children in relation to two aspects of relationships with family of origin: acceptance of sexual orientation and emotional closeness, and examined their potential role in the association between parenthood status and internalized homophobia. Data were collected from 472 LGBTQ adults aged 50+ from Israel, using an online questionnaire. The questionnaires assessed the family of origin relationship, internalized homophobia, and socio-demographic background of participants. Mediation models were used to examine the study hypotheses. The result showed that LGBTQ individuals with children reported lower level of internalized homophobia and higher levels of acceptance of sexual orientation and emotional closeness from their family of origin members. Mediation analyses indicated that the association between parenthood status and internalized homophobia was accounted for by acceptance of sexual orientation by one's family of origin. Parenthood was associated with lower internalized homophobia, which may reflect alignment with societal pronatalist norms and greater acceptance of one's sexual minority identity. However, alternative explanations, including reverse associations between internalized homophobia, family acceptance, and parenthood status, cannot be ruled out.
In the last 2 decades, there has been an increasing number of sexually transmissible enteric infection (STEI) outbreaks among gay, bisexual, or other men who have sex with men (GBMSM). There remain important gaps in our understanding of how STEI transmission is sustained that repeated collection of samples could help to address. This study aimed to assess the feasibility and acceptability of longitudinal samples and epidemiological data collection among GBMSM accessing sexual health services (SHS) through a prospective cohort study. GBMSM (≥16 years) accessing 2 SHS in Brighton and Sussex were recruited between May and October 2022. Participants provided an initial rectal swab and optional fecal sample and completed an online baseline questionnaire. Weekly follow-up questionnaires and rectal swabs were collected for a further 11 weeks. Sexually transmitted infection (STI) surveillance data were pseudonymously linked to provide additional clinical and demographic information. Selected participants were invited to take part in an optional one-to-one interview. We assessed the number completing study procedures, characteristics of those completing procedures and not, and representativeness of the study sample alongside facilitators and barriers from interviews. A chi-square test was used to compare groups. Overall, 193 participants were recruited. Half (100/193, 51.8%) provided a baseline rectal swab, with a third (34/100, 34.0%) of them providing all 12 swabs. Alongside the baseline swab, 76.0% (76/100) provided the optional fecal sample. Just over a third (71/193, 36.8%) of participants completed a baseline questionnaire, with a fifth (15/71, 21.1%) providing all follow-up questionnaires. Interviews (n=21) found that participation was motivated by the feeling of giving something back for services received and a perceived indirect benefit to self. The study was generally accepted, with over half reflecting on the perceived ease of participation and relatively simple tasks that could be easily integrated into normal routine with an element of flexibility. Most participants were satisfied with the 12-week study length, and having a definitive end point aided the ability to assess if they would be able to participate. Barriers to completing the study procedures included not being aware of what was required, particularly for the follow-up questionnaires. Suggested improvements included concise and easier-to-read instructions, with a section to clearly list out the key procedures of the study. SMS text messaging reminders were sent, but these were seen with variable utility and interpreted in different ways (eg, personal or generic reminders or thank you messages). This study has provided evidence that longitudinal rectal swab sampling and data collection for research purposes are feasible and acceptable among GBMSM attending SHS. This provides an innovative way to address important knowledge gaps about STEI transmission, which will help inform public health measures for infection control. Tangible insights from this pilot can also inform the design of similar studies in other settings.
Strangulation is often used in cases of intimate partner violence, sexual assault, and homicide. Strangulation is a particularly intimate form of asphyxia, involving manual or ligature-based external pressure applied to the front and sides of the neck. This study examines non-fatal non-consensual circumstances of strangulation experienced by 19 Australian men who have sex with men. Although their experiences were diverse, interpretative phenomenological analysis identified four prominent experiential themes. These themes included (1) Strangulation: A method of coercive control, (2) Blurry lines and shades of gray: The opacity of consent, (3) invisible men, silent victims: major long-term impacts, and (4) Controlling the narrative: Resilience and reclamation in the aftermath. Some of the findings are consistent with women's and heterosexual men's narratives of intimate partner violence and strangulation, highlighting common trends across culture, sexuality, gender, and relationship styles. However, there are also unique experiences of victimhood, health consequences, and sexual reclamation explored by these men. This study provides an Australian queer perspective on the growing phenomenon of non-consensual strangulation and presents information that should be given due consideration in future research, education, legal testimony, and policy development.
Long-acting injectable (LAI) antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) have significant potential to impact the HIV epidemic, but there is little data on the acceptability of these newer technologies among people who inject drugs (PWID) and men who have sex with men (MSM) in low-resource settings. We examined acceptability and preferences of LAI ART and PrEP among community-based samples of PWID and MSM in India. We conducted a cross-sectional survey of PWID and MSM in eight Indian cities (November 2022-May 2024) using respondent-driven sampling. Participants completed a survey including socio-demographics, substance use, risk behaviours, HIV testing/care history, acceptability of LAI ART and knowledge, acceptability, and preferences of different PrEP modalities (i.e. daily oral, monthly oral, LAI and implant). We assessed correlates of acceptability using Poisson regression models. To understand PrEP preferences, we used a modified Borda count method-a rank voting procedure. Overall, 2249 MSM and 4499 PWID (98% male) were recruited. Among those previously diagnosed with HIV, 89% (MSM) and 75% (PWID) reported a very good chance they would use LAI ART. MSM experiencing unstable housing and PWID virally suppressed were more willing to use LAI ART. Twenty percent and five percent of MSM and PWID, respectively, had ever heard of PrEP. Among those without an HIV diagnosis, 77% (MSM) and 62% (PWID) reported a very good chance they would use LAI PrEP. MSM with more sexual partners and sexually transmitted infection symptoms and PWID who had heard of PrEP were more willing to use LAI PrEP. Among MSM interested in PrEP, monthly oral pills were most preferred, followed by LAI, daily oral pills and then implant. Among PWID, monthly oral pills were most preferred, followed by daily oral pills, LAI and then implant. MSM and PWID in India were open and interested in LAI ART and PrEP. Once these become available, programmes with thoughtful community outreach and education, alongside flexible delivery models, will be critical to success. For PrEP, continued investment in the development of extended-duration oral formulations is warranted and valuable in order to provide a variety of HIV prevention choices.
This article considers the relationship between loneliness and queerness suggested by the quotation in its title, taken from Andrew Haigh's All of Us Strangers (2023). Throughout, I trace the causes and consequences of such a "queer loneliness" in both that film and Francis Lee's God's Own Country (2017). Despite the prevalence of loneliness in queer narratives, fictional and lived, queer loneliness has not received the critical attention paid to other negative queer emotions. To redress this oversight, I begin by considering the causes of queer loneliness and how the films' narratives complicate traditional explanations (the closet, rurality). Instead, I suggest, the films locate their characters' loneliness in perceived hostility from the world and an inability to connect with family and friends. I continue by considering the consequences of this loneliness in the films. I suggest the temporality of All of Us Strangers can be traced to Adam's loneliness, referencing queer temporality theory by Jack Halberstam and Eve Sedgwick. Finally, I follow Sara Ahmed's suggestion of queer loneliness as a generative emotion, re-appraising the depictions of loneliness in the films and arguing that, in the experiences of queer loneliness presented, loneliness allows new forms of connection to be made between characters.
This article documents and analyzes the evolution of queer nightlife in Costa rica between 1984 and 2024. Drawing on an original archival dataset constructed from 158 issues of seven LGBTIQ+ magazines and complemented with journalistic and cartographic sources, the study identifies 103 establishments oriented toward sexual and gender dissidents. The longitudinal inventory reveals changing patterns of growth, stabilization, and decline in the number of venues over four decades. While a contraction of establishments has also occurred in Costa Rica, the data indicate a temporal trajectory distinct from that documented in the Global North. Rather than an early boom followed by a long decline, Costa Rica experienced a later expansion during the mid-1990's and a subsequent contraction beginning in the 2010's. The findings also reveal a distinctive spatial configuration. Alongside the historical concentration of venues in San José, queer nightlife developed in tourism-driven enclaves such as Quepos and Tamarindo, small coastal towns where international tourism fostered unexpected hubs of queer sociability. These results suggest that processes often described as the "death of the gay bar" may unfold differently in Global South contexts and may reflect broader shifts in the spatial and organizational forms of queer nightlife.
Accurate knowledge among healthcare and mental health professionals caring for sexual and gender minority (SGM) youth is central to affirmative, culturally competent practice, yet it is frequently conflated with attitudes or self-perceived competence. This conflation limits detection of concrete knowledge gaps that may undermine clinical practice. The present study developed and validated the Sexual and Gender Minority Knowledge Scale (SGM-K), an objective measure of professional knowledge relevant to affirmative youth care. The scale was validated among healthcare and mental health professionals in Israel (N = 318). Analyses established a parsimonious, psychometrically sound instrument and examined associations with theoretically related and unrelated constructs. Findings supported a coherent structure encompassing foundational knowledge of sexual and gender diversity, key concepts and terminology, and clinically relevant awareness of disparities, diagnostic considerations, and policy contexts. The scale demonstrated acceptable reliability. Knowledge was moderately associated with affirmative beliefs, behaviors, and attitudes; showed negligible relations with perceived societal tolerance; and differentiated professionals by training, personal contact, and clinical experience. The SGM-K offers a brief, objective, theory-driven tool for research, workforce development, and evaluation of affirmative care initiatives. Future research should examine cross-national validity and measurement invariance across cultural settings.
While current studies utilizing Foucault's concept of subject formation convincingly explain how macro-level forces such as neoliberal ideologies and school policies shape individuals, finer attention to the meaning-making and life influences of the subjects themselves is equally important to nuance our understanding of how capillary power operates. Focusing on a single case, this study examines the subject formation of a Filipino gay professor. Using narrative analysis, the study identifies three themes supported by six vignettes. The findings reveal compelling stories of how a gay professor was shaped by the mentoring of his gay "parlorista" uncles, only to paradoxically become their exact opposite. Concepts such as dichotomization, discourses on being a distinguished gay professor, power relations, and governmentalization are analyzed to highlight the complex negotiations through which the gay professor's subjectivity is constituted.
Coming-out is a continuous process within LGBTQ communities, involving self-recognition and identity disclosure in the presence of family and friends, shaped by journeys of self-acceptance and by societal attitudes that significantly influence the dynamics of identity affirmation. This study employs Critical Discourse Analysis (CDA) to examine the fictional, scripted online series "About Him," produced by Signal 23, which depicts four queer Black men, Damien, Vincent, Kendall, and Justin, navigating identity development, community expectations, and public perception through the journey of coming-out. Drawing on the intersection of queer and color critique, this analysis examines how visual framing, dialogue, and narrative sequences construct Black queer disclosure as a negotiation within racialized, heteronormative systems. The exploration of the intersection between self-acceptance and identity affirmation within the coming-out process, using data analysis, was examined across 13 episodes of season 1. The findings reveal that the series frames coming-out not simply as personal authenticity, but as a strategic process shaped by masculinity performance, cultural dynamics, identity concealment, and resistance, functioning not as narrative failures but as adaptive responses to intersecting pressures. By centering mediated representation in the study, it extends scholarship to demonstrate how fictional media texts actively participate in constructing LGBTQ lifestyles around Black male queerness. The exploration of the intersection between self-acceptance and identity affirmation within the coming-out process through data analysis was used from the series to answer two research questions: (1) How does the coming-out process contribute to self-discovery and identity development among individuals exploring their sexual orientation or gender identity? (2) How do societal attitudes and cultural factors influence the coming-out experiences of individuals identifying as gay? Furthermore, the analysis examined discourse and discursive practices through narrative and character depictions categorized into four key themes: (1) self-discovery, (2) identity development, (3) societal attitudes, and (4) identity concealment, as portrayed in the media landscape, which contribute to ongoing conversations about sexuality, representation of race, and masculinity in LGBTQ media scholarship.
This article outlines the findings of research about rainbow people's perspectives on New Zealand's Police. It analyses 11 semi-structured interviews with rainbow people in New Zealand. First, participants reflected on what they saw as the role police play in New Zealand society. Some felt that police played an important role in maintaining the status quo relations of power, while others saw them playing a public safety role. Participants also expressed frustration with what they saw as police misunderstandings of rainbow people's needs, in relation to justice. While some participants were positive about police's adoption of rainbow "image work," sometimes criticized as "pinkwashing," most felt that efforts, alongside the introduction of diversity liaison officers remained tokenistic. Finally, the participants, who all had experiences interacting with police as a victim, bystander or alleged offender, expressed reservations about reporting any future victimization to police. While they saw a limited set of circumstances in which they would do so, many spoke to the lack of trust and understanding that underpinned their previous experiences. The article paints a complex and contradictory picture about rainbow people's perceptions of New Zealand police and challenge the assumption that New Zealand remains a bastion of progress on rainbow rights.
Drawing on Miranda Fricker's "hermeneutical marginalization" and Martin Meeker's "sexual communication network," this article retraces how the adoption and therefore the existence of queer identities are predicated on the availability of alternative models of understanding sexuality. "Loci of increased human connection," such as cities, media, and the Internet, are recognized as disseminators of hermeneutical resources and catalysts for "sexual communication networks." By following this throughline, this article provides a framework for the social ontology of sexual orientation that is intended to be usable across history. The author renegotiates the debate about the applicability of sexual orientation lingo to queer pre-modern history by iterating on William Wilkerson's emerging fusion theory of sexual identity. Sexual orientation is a self-interpretation of desires, which emerge, or remain hermeneutically marginalized, under the available social models that are specific to each society (and time). Historiography, in this way, can realistically enquire about sexual preference in its search for "gay history"; particular focus must be put, however, on "loci of increased human connection," because they are the most likely sites where hermeneutically underserved desires might emerge explicitly as alternative social categories. These alternative categories might have lived only in limited contexts before the invention of modern communication technologies.
Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) clients often receive suboptimal mental health care. LGBTQ+ clinical competence self-report measures have been developed to assess therapists' knowledge and attitudes and subjective self-perceived skills and performance. However, therapist self-perceived assessments of their skills and performance have been found to be biased. Observational measures of LGBTQ+ competence are needed to more objectively evaluate therapists' skills and performance. The objective of this exploratory pilot study was to develop and assess the coding reliability of observational measures of therapists' competence with LGBTQ+ clients. The observational measure developed and tested in this study consisted of 29 items that corresponded to 29 expected competencies applicable to LGBTQ+ competent and ethical therapy. On-line initial consultations between 43 therapists and a simulated client were video recorded. Two trained self-identifying LGBTQ+ coders observed the video-recordings and used the 29 items to rate the LGBTQ+ competencies of these 43 therapists. We generated item proportions and kappa statistics. This preliminary study suggests that 13 measures of LGBTQ+ clinical competence were operationally defined to be observable, measurable, and reliably coded. Future research is warranted to both confirm and expand on this conclusion to advance evidence-based approaches to improve the mental health care for LGBTQ+ clients.
This article provides the first examination focused exclusively on the family lives of queer Palestinians, moving beyond reductive Western media and pinkwashing portrayals that often spectacularize sporadic violence. Drawing on semi-structured interviews with 53 queer Palestinians living in Palestine-Israel, this study utilizes a decolonial framework to analyze the family as a primary institution of relational sovereignty. The findings suggest that while initial familial responses to "coming out" are often shaped by pathologizing frameworks-such as "disease" or "possession"-these reactions are frequently defensive maneuvers against communal surveillance and settler-colonial scrutiny. The study identifies a dynamic process of "relational repair," where families perform domestic labor to reinterpret gender and sexual norms, shifting from initial rejection toward affirmation. By centering these everyday negotiations, I argue that the Palestinian family is an adaptive site capable of enacting its own decolonial transformations. This transition disrupts Zionist pinkwashing narratives by positioning the family not as an irredeemable site of repression, but as a resilient foundation for queer survival and indigenous belonging. Ultimately, queer liberation is shown to be inextricably linked to the endurance and evolution of the family unit under the weight of apartheid.
Pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention strategy, yet its uptake among men who have sex with men (MSM) in China remains low. This study aimed to assess whether city-level differences influence the PrEP awareness, willingness, and ever-use among MSM in China. A secondary analysis of a national cross-sectional survey of MSM (n = 5041) from 42 Chinese cities was conducted. We fitted generalized linear mixed models with city as a random intercept for awareness and ever-use. Willingness showed no significant clustering by city and was analyzed using logistic regression. Independent variables were grouped according to Andersen's Behavioral Model of Health Services Use into predisposing, enabling, and need-related factors. Interclass correlation (ICC) quantifies the variance between cities. The majority (87.2%) had heard of PrEP, 58.4% were willing to use it, and 13.0% had ever used it. In fully adjusted models, city-level clustering remained evident for PrEP awareness (ICC = 5.3%, P = 0.003) and ever-use (ICC = 8.1%, P = 0.011), indicating a measurable influence of place of residence. Willingness showed no significant between-city variation. PrEP awareness was higher among younger MSM (aOR = 0.98, P < 0.05) and those with lower income (< 3000 CNY: aOR = 0.67, P < 0.05), and not knowing partners' HIV status (aOR = 0.57, P < 0.001) was associated with reduced awareness. Willingness to use PrEP was lower among those earning < 3000 CNY (aOR = 0.75, P < 0.05), positively associated with higher per capita health expenditure (aOR = 1.02, P < 0.05), and negatively associated with higher HIV prevalence (aOR = 0.96, P < 0.01). Ever use of PrEP was associated with condomless sex (aOR = 1.62, P < 0.001), while lower income (< 3000 CNY: aOR = 0.45, P < 0.001) remained a significant barrier. Place of residence affects PrEP awareness and use, but not willingness. However, actual use is primarily driven by individual-level factors. HIV prevention in China should combine city-level service expansion with targeted individual-level interventions to close the gap between PrEP awareness, willingness, and actual use.
This article reexamines the political and theoretical project of Guy Hocquenghem, a key yet often misread figure of post-1968 radical thought. Moving beyond the standard reception that limits him to early gay liberation, I argue that Hocquenghem elaborates a sustained critique of identity, community, and normalization that remains urgently relevant today. Through a close engagement with Anti-Oedipus, I show how his analysis of homosexual desire operates as a critique of Oedipal subjectivation and as a precondition for revolutionary politics. The article then revisits the Front homosexuel d'action révolutionnaire (FHAR) as a "war machine" whose collective experimentations-rather than any doctrine-embodied a politics of desire irreducible to identity affirmation. In the mid-1970s, Hocquenghem turned this critique against emerging gay normalizations, consumerist cultures, and legalist politics, defending instead the minoritarian force of delinquent homosexuality. Finally, I explore his late writings on foreignness, where desire becomes a transversal movement that unsettles national, sexual, and subjective boundaries. Hocquenghem's work, I contend, offers conceptual tools that challenge contemporary queer politics oriented around recognition and fixed or additive conceptions of identity (including certain reductive uses of intersectionality), insisting on a politics of alterity, drift, and desubjectivation. Re-reading Hocquenghem today is not an antiquarian exercise but a way to rethink the politics of sexuality beyond identity.
This study investigates workplace sexual harassment (WSH) among 2,031 women across four major Chinese cities, including 384 queer women, offering one of the first large-scale analyses of sexual minority women's experiences in the contemporary Chinese context. Results reveal that queer women experience higher prevalence, greater variety, and more frequent WSH than heterosexual women. Patterns of perpetration also diverge: queer women are disproportionately harassed by colleagues, whereas heterosexual women more often face harassment from clients. Multivariate analyses further reveal the influence of age, employment status, housing insecurity, and endorsement of traditional gender norms, while knowledge of legal protections and social support reduces vulnerability. These findings highlight the disadvantages faced by both heterosexual and queer women in urban China and emphasize the urgent need for targeted legal, organizational, and cultural interventions to safeguard women, especially sexual minorities, in the workplace.
Sexual and gender diverse people accessing maternity services may face stigma and exclusion due to a lack of inclusive midwifery education. Traditional midwifery philosophy centers on women, often marginalizing those whose gender identities fall outside binary norms. Despite growing awareness of gender-affirming care, midwifery education remains poorly equipped to prepare students and professionals for inclusive practice. This scoping review examines how tertiary and clinical midwifery education prepares midwives and students to care for sexually and gender diverse people within maternity services. It identifies existing strengths, gaps, and opportunities for improvement, with the aim of informing educational, clinical, and policy reform in the Australian context. Using the Joanna Briggs Institute PCC framework and PRISMA-ScR guidelines, peer-reviewed literature from 2004 to 2026 was sourced from five databases. Twelve studies met inclusion criteria and were thematically analyzed. Three key themes emerged: Gaps in curricula on sexual and gender diversity; The role of identity, communication, and emotional safety; and The need for inclusive, respectful clinical environments. Educational content was fragmented, inconsistently delivered, and underpinned by cis-heteronormative assumptions. These findings highlight a critical gap in educator preparedness and curriculum design. In the absence of inclusive education, midwives may be inadequately equipped to provide affirming care, thereby perpetuating existing disparities. Urgent reform across curricula, professional development, and policy is required to promote equitable maternity care for sexual and gender diverse people.
Squamous cell carcinoma of the anus (SCCA), caused by high-risk human papillomavirus (HR-HPV) genotypes, is a growing concern among gay, bisexual, and other men who have sex with men and transgender individuals, particularly those living with HIV. Early detection of precursor lesions is crucial, yet current screening methods face barriers in access and acceptability. Anal self-sampling has emerged as a promising patient-centered alternative. This study evaluates the diagnostic accuracy and feasibility of self-collected anal swabs for HPV genotyping compared to clinician-collected swabs among the target population. A cross-sectional, multicenter study was conducted in the metropolitan area of Barcelona, enrolling 151 participants. Participants provided self- and clinician-collected anal samples, obtained sequentially. Extended genotyping was performed to detect 28 individual HPV genotypes. Diagnostic performance was evaluated using clinician-collected samples as the reference standard, and concordance was assessed using McNemar's test and Cohen's κ statistic. Feasibility was measured via a questionnaire. Participants had a median age of 43 years, and 53.0% were living with HIV. Overall, HPV was detected in 89.9% of self- and 92.6% of clinician-collected samples. Agreement was high 96.0%, with a κ value of 0.75 (95% CI: 0.55-0.94). No significant differences were found between methods (p = 0.22). Sensitivity was 96.4% (95% CI: 91.8-98.4), and specificity 90.9% (95% CI: 62.3-98.4), with similar accuracy for HR-HPV and HPV16 types. Most participants rated self-sampling acceptable and feasible. Anal self-sampling shows high accuracy and strong feasibility, supporting its use as a viable and user-friendly strategy to enhance HPV screening in key populations at risk for SCCA.
HIV disproportionately affects men who have sex with men (MSM), transgender individuals, and people who inject drugs, with 70.1% of cases in Pakistan linked to these groups, aggravated by stigma and legal constraints. Mobile health (mHealth) interventions offer the potential to enhance HIV prevention, yet their acceptability remains underexplored. This study aimed to assess the feasibility, willingness to use, and preferences for mHealth-based interventions designed to improve HIV knowledge, testing uptake, and risk behavior reduction among MSM, transgender individuals, and people who inject drugs in Pakistan. A cross-sectional survey was conducted from February 2025 to May 2025 with 210 participants, including MSM and transgender individuals, recruited through respondent-driven sampling in collaboration with community-based organizations and nongovernmental organizations, while people who inject drugs were recruited from the rehabilitation centers of trusted community-based organizations and nongovernmental organizations, to ensure privacy and reduce safety concerns. Participants completed a self-administered questionnaire covering demographics, HIV knowledge, access to and use of mobile technology, acceptability and preferences for mHealth interventions, and HIV-related risk behaviors. The majority of participants owned smartphones (161/210, 76.7%) and had daily internet access (115/210, 54.8%), spending an average of 3.41 (SD 3.10) hours online daily. High willingness (182/210, 86.7%) to use a clinic-integrated mHealth app for HIV prevention was reported. Preferred app-delivered features included educational resources (85/210, 40.5%), daily medication reminders (108/210, 51.4%), weekly HIV prevention information (110/210, 52.4%), e-consultation (158/210, 75.2%), and mental health information (134/210, 63.8%). Smartphone ownership (odds ratio 4.14, 95% CI 1.41-12.21; P=.009) and prior experience with an mHealth app (odds ratio 2.97, 95% CI 1.00-8.81; P=.05) were significantly associated with willingness to adopt an mHealth app. While 80.5% (169/210) reported some knowledge of HIV, only 17.1% (29/169) rated their knowledge high, and 46.1% (97/210) were unaware of their HIV status. In terms of vulnerability, participants reported that injected drug use (122/210, 58.1%), experiences of violence (87/210, 41.4%), and police detention (128/210, 61%) were prevalent. In terms of risky sexual behaviors, nearly half engaged in transactional sex (104/210, 49.5%) or had multiple partners (101/210, 48.1%), while consistent condom use remained low (90/210, 42.9%). There is high acceptability and considerable potential for mHealth interventions to enhance HIV prevention efforts among MSM, transgender individuals, and people who inject drugs in Pakistan. Tailored, discreet, and comprehensive mHealth platforms that include educational content, medication reminders, e-consultation, and mental health support are warranted. Addressing criminalization and ensuring user privacy will be crucial for the successful design and implementation of these interventions. Future research should focus on implementation research to assess the real-world uptake of these findings.