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As computational capacity increases, it becomes possible to model health systems in greater detail. Multi-disease health system models (HSMs) represent a new development, building on individual level epidemiological models of multiple diseases and capturing how healthcare delivery systems respond to population health needs. The Thanzi la Onse (TLO) model of Malawi is the first of its kind in these respects. In this article, we discuss how we have been bringing economic concepts into the TLO model, and how we are continuing to develop this line of research. This has involved incorporating more sophisticated approaches to account for the effects of the unavailability of healthcare workers, and we are working towards establishing the role of different forms of ownership of healthcare facilities and different management practices. Not only does this broad approach make the model more flexible as a tool for understanding the impact of resource constraints, it opens up the possibility of analysing considerably richer policy scenarios; for example establishing an estimate of the health gain that could be achieved through expanding the workforce or reducing healthcare worker absence.

Mobile health has the potential to revolutionize health care delivery and patient engagement. In this work, we discuss how integrating Artificial Intelligence into digital health applications-focused on supply chain, patient management, and capacity building, among other use cases-can improve the health system and public health performance. We present an Artificial Intelligence and Reinforcement Learning platform that allows the delivery of adaptive interventions whose impact can be optimized through experimentation and real-time monitoring. The system can integrate multiple data sources and digital health applications. The flexibility of this platform to connect to various mobile health applications and digital devices and send personalized recommendations based on past data and predictions can significantly improve the impact of digital tools on health system outcomes. The potential for resource-poor settings, where the impact of this approach on health outcomes could be more decisive, is discussed specifically. This framework is, however, similarly applicable to improving efficiency in health systems where scarcity is not an issue.

This research examines the persistent challenge of health inequalities in India, departing from the conventional focus on aggregate improvements in mortality rates. While India has achieved progress in overall health indicators since independence, the distribution of health outcomes remains uneven, a fact starkly highlighted by the COVID-19 pandemic. This study investigates the socio-economic determinants of health disparities using the National Family and Health Survey (NFHS)-5 data from 2019-20, focusing on both national and state-level analyses, specifically for Maharashtra. Employing a health economics framework, the analysis delves into individual-level data, population shares, self-reported morbidity prevalence, and treatment patterns across diverse socio-economic groups. Regression analyses, stratified by gender, are conducted to quantify the impact of socio-economic factors on reported morbidity. Furthermore, a Fairlie decomposition, an extension of the Oaxaca decomposition, is utilised to dissect the gender gap in morbidity, assessing the extent to which observed differences are attributable to explanatory variables. The findings reveal a significant burden of self-reporte

The integration of voice-based AI agents in healthcare presents a transformative opportunity to bridge economic and accessibility gaps in digital health delivery. This paper explores the role of large language model (LLM)-powered voice assistants in enhancing preventive care and continuous patient monitoring, particularly in underserved populations. Drawing insights from the development and pilot study of Agent PULSE (Patient Understanding and Liaison Support Engine) -- a collaborative initiative between IBM Research, Cleveland Clinic Foundation, and Morehouse School of Medicine -- we present an economic model demonstrating how AI agents can provide cost-effective healthcare services where human intervention is economically unfeasible. Our pilot study with 33 inflammatory bowel disease patients revealed that 70\% expressed acceptance of AI-driven monitoring, with 37\% preferring it over traditional modalities. Technical challenges, including real-time conversational AI processing, integration with healthcare systems, and privacy compliance, are analyzed alongside policy considerations surrounding regulation, bias mitigation, and patient autonomy. Our findings suggest that AI-driven

YouTube has rapidly emerged as a predominant platform for content consumption, effectively displacing conventional media such as television and news outlets. A part of the enormous video stream uploaded to this platform includes health-related content, both from official public health organizations, and from any individual or group that can make an account. The quality of information available on YouTube is a critical point of public health safety, especially when concerning major interventions, such as vaccination. This study differentiates itself from previous efforts of auditing YouTube videos on this topic by conducting a systematic daily collection of posted videos mentioning vaccination for the duration of 3 months. We show that the competition for the public's attention is between public health messaging by institutions and individual educators on one side, and commentators on society and politics on the other, the latest contributing the most to the videos expressing stances against vaccination. Videos opposing vaccination are more likely to mention politicians and publication media such as podcasts, reports, and news analysis, on the other hand, videos in favor are more li

This research paper presents a meta-analysis of the multifaceted role of technology in mental health. The pervasive influence of technology on daily lives necessitates a deep understanding of its impact on mental health services. This study synthesizes literature covering Behavioral Intervention Technologies (BITs), digital mental health interventions during COVID-19, young men's attitudes toward mental health technologies, technology-based interventions for university students, and the applicability of mobile health technologies for individuals with serious mental illnesses. BITs are recognized for their potential to provide evidence-based interventions for mental health conditions, especially anxiety disorders. The COVID-19 pandemic acted as a catalyst for the adoption of digital mental health services, underscoring their crucial role in providing accessible and quality care; however, their efficacy needs to be reinforced by workforce training, high-quality evidence, and digital equity. A nuanced understanding of young men's attitudes toward mental health is imperative for devising effective online services. Technology-based interventions for university students are promising, al

A fundamental challenge for modern economics is to understand what happens when actors in an economy are replaced with algorithms. Like rationality has enabled understanding of outcomes of classical economic actors, no-regret can enable the understanding of outcomes of algorithmic actors. This review article covers the classical computer science literature on no-regret algorithms to provide a foundation for an overview of the latest economics research on no-regret algorithms, focusing on the emerging topics of manipulation, statistical inference, and algorithmic collusion.

The Oregon Health Insurance Experiment (OHIE) offers a unique opportunity to examine the causal relationship between Medicaid coverage and happiness among low-income adults, using an experimental design. This study leverages data from comprehensive surveys conducted at 0 and 12 months post-treatment. Previous studies based on OHIE have shown that individuals receiving Medicaid exhibited a significant improvement in mental health compared to those who did not receive coverage. The primary objective is to explore how Medicaid coverage impacts happiness, specifically analyzing in which direction variations in healthcare spending significantly improve mental health: higher spending or lower spending after Medicaid. Utilizing instrumental variable (IV) regression, I conducted six separate regressions across subgroups categorized by expenditure levels and happiness ratings, and the results reveal distinct patterns. Enrolling in OHP has significantly decreased the probability of experiencing unhappiness, regardless of whether individuals had high or low medical spending. Additionally, it decreased the probability of being pretty happy and having high medical expenses, while increasing the

We present a theoretical framework assessing the economic implications of bias in AI-powered emergency response systems. Integrating health economics, welfare economics, and artificial intelligence, we analyze how algorithmic bias affects resource allocation, health outcomes, and social welfare. By incorporating a bias function into health production and social welfare models, we quantify its impact on demographic groups, showing that bias leads to suboptimal resource distribution, increased costs, and welfare losses. The framework highlights efficiency-equity trade-offs and provides economic interpretations. We propose mitigation strategies, including fairness-constrained optimization, algorithmic adjustments, and policy interventions. Our findings offer insights for policymakers, emergency service providers, and technology developers, emphasizing the need for AI systems that are efficient and equitable. By addressing the economic consequences of biased AI, this study contributes to policies and technologies promoting fairness, efficiency, and social welfare in emergency response services.

We study how nonlinear, state-dependent health dynamics shape economic behavior, inequality, and the evaluation of disability insurance at older ages. Using English panel data, we construct a continuous health index and estimate its dynamics with a flexible quantile-based method that allows persistence to vary across health states. We find that adverse health realizations are both larger and more persistent among individuals in poor health. Embedding the estimated process into a life-cycle model, we show that these state-dependent nonlinearities generate substantial losses in assets and welfare for economically vulnerable individuals-those with poor health and low wealth. Misspecifying health dynamics as state-independent attenuates these losses and leads to distorted savings behavior, with effects concentrated among vulnerable individuals. Finally, we find that the welfare losses of removing disability insurance are highly heterogeneous across health types, and are overstated by a state-independent health process.

Abundant evidence has tracked the labour market and health assimilation of immigrants, including static analyses of differences in how foreign-born and native-born residents consume health care services. However, we know much less about how migrants' patterns of health care usage evolve with time of residence, especially in countries providing universal or quasi-universal coverage. We investigate this process in Spain by combining all the available waves of the local health survey, which allows us to separately identify period, cohort, and assimilation effects. We find that the evidence of health assimilation is limited and solely applies to migrant females' visits to general practitioners. Nevertheless, the differential effects of ageing on health care use between foreign-born and native-born populations contributes to the convergence of utilisation patterns in most health services after 20 years in Spain. Substantial heterogeneity over time and by region of origin both suggest that studies modelling future welfare state finances would benefit from a more thorough assessment of migration.

Mobile health apps are revolutionizing the healthcare ecosystem by improving communication, efficiency, and quality of service. In low- and middle-income countries, they also play a unique role as a source of information about health outcomes and behaviors of patients and healthcare workers, while providing a suitable channel to deliver both personalized and collective policy interventions. We propose a framework to study user engagement with mobile health, focusing on healthcare workers and digital health apps designed to support them in resource-poor settings. The behavioral logs produced by these apps can be transformed into daily time series characterizing each user's activity. We use probabilistic and survival analysis to build multiple personalized measures of meaningful engagement, which could serve to tailor content and digital interventions suiting each health worker's specific needs. Special attention is given to the problem of detecting churn, understood as a marker of complete disengagement. We discuss the application of our methods to the Indian and Ethiopian users of the Safe Delivery App, a capacity-building tool for skilled birth attendants. This work represents an

The rise of foundation models has driven the emergence of AI supply chains, where upstream foundation model providers offer fine-tuning and inference services to downstream firms developing domain-specific applications. Downstream firms pay providers to use their computing infrastructure to fine-tune models with proprietary data, creating a co-creation dynamic that enhances model quality. Amid concerns that foundation model providers and downstream firms may capture excessive consumer surplus, along with increasing regulatory measures, this study employs a game-theoretic model involving a provider and two competing downstream firms to analyze how policy interventions affect consumer surplus in the AI supply chain. Our analysis shows that policies promoting price competition in downstream markets (i.e., pro-price-competitive policies) boost consumer surplus only when compute or data preprocessing costs are high, while compute subsidies are effective only when these costs are low, suggesting these policies complement each other. In contrast, policies promoting quality competition in downstream markets (i.e., pro-quality-competitive policies) always improve consumer surplus. We also f

We study the long-term health and human capital impacts of local economic conditions experienced during the first 1,000 days of life. We combine historical data on monthly unemployment rates in urban England and Wales 1952-1967 with data from the UK Biobank on later-life outcomes. Leveraging variation in unemployment driven by national industry-specific shocks weighted by industry's importance in each area, we find no evidence that small, common fluctuations in local economic conditions during the early life period affect health or human capital in older age.

With the reversal of Roe v. Wade in 2022, many U.S. employers announced they would reimburse employees for abortion-related travel expenses. This action complements increasingly common employer policies subsidizing employee access to assisted reproductive technologies such as in-vitro fertilization and egg freezing. This article reflects on why employers offer these benefits and whether they enhance or undermine reproductive justice. From the employer's perspective, abortion and assisted reproductive technologies help women to plan childbearing around the demands of their jobs. Both are associated with delayed childbirth and reduced fertility, which lower the costs of motherhood to employers. However, firm subsidization of these services does not further reproductive justice because it reifies structures which incentivize women to delay childbirth and reduce fertility, and it reinforces economic and reproductive inequalities. We conclude by questioning whether reproductive justice is possible without transforming the economy so that it prioritizes care over profits.

This paper establishes the theoretical and practical foundations for using Large Language Models (LLMs) as measurement instruments for latent economic variables -- specifically variables that describe the cognitive content of occupational tasks at a level of granularity not achievable with existing survey instruments. I formalize four conditions under which LLM-generated scores constitute valid instruments: semantic exogeneity, construct relevance, monotonicity, and model invariance. I then apply this framework to the Augmented Human Capital Index (AHC_o), constructed from 18,796 O*NET task statements scored by Claude Haiku 4.5, and validated against six existing AI exposure indices. The index shows strong convergent validity (r = 0.85 with Eloundou GPT-gamma, r = 0.79 with Felten AIOE) and discriminant validity. Principal component analysis confirms that AI-related occupational measures span two distinct dimensions -- augmentation and substitution. Inter-rater reliability across two LLM models (n = 3,666 paired scores) yields Pearson r = 0.76 and Krippendorff's alpha = 0.71. Prompt sensitivity analysis across four alternative framings shows that task-level rankings are robust. Obv

Most health economic analyses are undertaken with the aid of computers. However, the research ethics of implementing health economic models as software (or computational health economic models (CHEMs)) are poorly understood. We propose that developers and funders of CHEMs should adhere to research ethics principles and pursue the goals of: (i) socially acceptable user requirements and design specifications; (ii) fit for purpose implementations; and (iii) socially beneficial post-release use. We further propose that a transparent (T), reusable (R) and updatable (U) CHEM is suggestive of a project team that has largely met these goals. We propose six criteria for assessing TRU CHEMs: (T1) software files are publicly available; (T2) developer contributions and judgments on appropriate use are easily identified; (R1) programming practices facilitate independent reuse of model components; (R2) licenses permit reuse and derivative works; (U1) maintenance infrastructure is in place; and (U2) releases are systematically retested and deprecated. Few existing CHEMs would meet all TRU criteria. Addressing these limitations will require the development of new and updated good practice guidelin

This paper presents a novel quantitative approach for comparative economic studies, addressing limitations in current classification methods. Conventional approaches in comparative economics often rely on ad hoc and categorical classifications, leading to subjective judgments and disregarding the continuous nature of the spectrum of economic systems. These can result in subjectivity and significant information loss, particularly for countries with systems near categorical borders. To overcome these shortcomings, the present paper proposes distance-based indices for objective categorization, considering economic foundations and using hard data. Accordingly, the paper introduces institutional similarity indices--Capitalism Similarity Index (CapSI), Communism Similarity Index (ComSI), and Socialism Similarity Index (SocSI)-which reflect countries' positions along the economic system continuum. These indices adhere to mathematical rigor and are grounded in the mathematical fields of real analysis, metric spaces, and distance functions. By classifying 135 countries and creating GIS maps, the practical applicability of the proposed approach is demonstrated. Results show a high explanator

We are developing an economic model to explore multiple topics in Australian youth mental health policy. We want that model to be readily transferable to other jurisdictions. We developed a software framework for authoring transparent, reusable and updatable Computational Health Economic Models (CHEMs) (the software files that implement health economic models). We specified framework user requirements of a template CHEM module that facilitates modular model implementations, a simple programming syntax and tools for authoring new CHEM modules, supplying CHEMs with data, reporting reproducible CHEM analyses, searching for CHEM modules and maintaining a CHEM project website. We implemented the framework as six development version code libraries in the programming language R that integrate with online services for software development and research data archiving. We used the framework to author five development version R libraries of CHEM modules focused on utility mapping in youth mental health. These modules provide tools for variable validation, dataset description, multi-attribute instrument scoring, construction of mapping models, reporting of mapping studies and making out of sam