共找到 20 条结果
This study evaluated self-reported response certainty across several large language models (GPT, Claude, Llama, Phi, Mistral, Gemini, Gemma, and Qwen) using 300 gastroenterology board-style questions. The highest-performing models (GPT-o1 preview, GPT-4o, and Claude-3.5-Sonnet) achieved Brier scores of 0.15-0.2 and AUROC of 0.6. Although newer models demonstrated improved performance, all exhibited a consistent tendency towards overconfidence. Uncertainty estimation presents a significant challenge to the safe use of LLMs in healthcare. Keywords: Large Language Models; Confidence Elicitation; Artificial Intelligence; Gastroenterology; Uncertainty Quantification
Radiology reports remain the primary mechanism by which imaging findings are communicated to clinical teams. However, much of the structured information behind these reports, including measurements, image evidence, prior comparisons, lesion identity, uncertainty, and terminology, often remains trapped in free text or fragmented across picture archiving and communication systems, radiology information systems, reporting workstations, worksheets, advanced visualization tools, and electronic health records. This paper proposes a human-supervised, evidence-linked reference architecture for structured radiology reporting. The framework combines exam-specific templates, speech-to-structure processing, measurement and segmentation capture, controlled AI-assisted drafting, and standards-based interoperability using DICOM, DICOM Structured Reporting, DICOM Segmentation, HL7 FHIR, RadLex, SNOMED CT, LOINC, and UCUM. The system is positioned not as an autonomous report generator, but as a structured intelligence layer for enterprise imaging that supports reviewed reporting, longitudinal comparison, clinical data reuse, governance, and integration with PACS, RIS, EHR, analytics, and registry w
In the dynamic landscape of modern healthcare, maintaining the highest standards in surgical instruments is critical for clinical success. This report explores the diverse realm of surgical instruments and their associated manufacturing defects, emphasizing their pivotal role in ensuring the safety of surgical procedures. With potentially fatal consequences arising from even minor defects, precision in manufacturing is paramount.The report addresses the identification and rectification of critical defects such as cracks, rust, and structural irregularities. Such scrutiny prevents substantial financial losses for manufacturers and, more crucially, safeguards patient lives. The collaboration with industry leaders Daddy D Pro and Dr. Frigz International, renowned trailblazers in the Sialkot surgical cluster, provides invaluable insights into the analysis of defects in Pakistani-made instruments. This partnership signifies a commitment to advancing automated defect detection methodologies, specifically through the integration of deep learning architectures including YOLOv8, ResNet-152, and EfficientNet-b4, thereby elevating quality standards in the manufacturing process. The scope of t
Background: Artificial intelligence (AI) has emerged as a disruptive innovation in medicine, yet its adoption within gastroenterology remains limited and poorly characterized. We aimed to examine knowledge, practical applications, perceived barriers, and expectations regarding AI among gastroenterology specialists in Spain. Methods: We conducted a cross-sectional observational study using a structured online survey distributed by the Spanish Society of Digestive Pathology (SEPD) in 2025. The questionnaire collected sociodemographic data, patterns of AI use, perceptions, and educational needs. Descriptive statistics and multivariable models were applied. Results: Among 283 respondents (mean age 44.6 +/- 9.7 years), 87.5% acknowledged AI as a transformative tool, but only 60.2% (95% CI: 54.3-66.1%) reported using it, mostly outside institutional frameworks. Notably, 80.2% of users initiated AI use within the past year. Independent predictors of frequent use included previous training (OR=2.44), employment in university hospitals (OR=2.14), and younger age (OR=1.36 per 5-year decrease). Main barriers were lack of training (61%), absence of institutional strategies (46%), and ethical c
This is the interim publication of the first International Scientific Report on the Safety of Advanced AI. The report synthesises the scientific understanding of general-purpose AI -- AI that can perform a wide variety of tasks -- with a focus on understanding and managing its risks. A diverse group of 75 AI experts contributed to this report, including an international Expert Advisory Panel nominated by 30 countries, the EU, and the UN. Led by the Chair, these independent experts collectively had full discretion over the report's content. The final report is available at arXiv:2501.17805
We analyzed 3,984 AI agent skills from major marketplaces and found 76 confirmed malicious payloads, including credential theft, backdoor installation, and data exfiltration. 13.4% of all skills contain at least one critical-level security issue and at least 8 manually confirmed malicious skills remain publicly available on clawhub.ai as of the date of publication. This report documents our methodology, presents a threat taxonomy based on real-world samples, and details the attack patterns we observed. As skill marketplaces grow rapidly and AI agents gain access to sensitive credentials and systems, automated security analysis is no longer optional.
In this report, we present HoloMotion-1, a humanoid motion foundation model for zero-shot whole-body motion tracking. A key innovation of HoloMotion-1 is to scale control-policy training with a large-scale hybrid motion corpus, where video-reconstructed motions from in-the-wild videos provide the dominant source of motion diversity, while curated motion-capture and in-house motion data provide higher-fidelity supervision and deployment-oriented coverage. This data regime enables HoloMotion-1 to move beyond conventional MoCap-only training and exposes the policy to substantially broader behaviors, capture conditions, and motion styles. Learning from such heterogeneous data introduces new challenges, including reconstruction noise, source-domain mismatch, uneven motion quality, and the need for temporal modeling under large behavioral variation. To address these challenges, HoloMotion-1 integrates large-capacity temporal modeling, a sparsely activated Mixture-of-Experts Transformer with KV-cache inference for real-time control, and a sequence-level training strategy that improves learning efficiency on extended motion sequences. Extensive experiments on multiple unseen motion benchma
Large language models (LLMs) have shown remarkable success across many domains, yet their integration into cybersecurity applications remains limited due to a lack of general-purpose cybersecurity data, representational complexity, and safety and regulatory concerns. To address this gap, we previously introduced Foundation-Sec-8B, a cybersecurity-focused LLM suitable for fine-tuning on downstream tasks. That model, however, was not designed for chat-style interactions or instruction-following. In this report, we release Foundation-Sec-8B-Instruct: a model specifically trained for general-purpose cybersecurity dialogue. Built on Foundation-Sec-8B, it combines domain-specific knowledge with instruction-following, conversational capabilities, and alignment with human preferences to produce high-quality, relevant responses. Comprehensive evaluations show that Foundation-Sec-8B-Instruct outperforms Llama 3.1-8B-Instruct on a range of cybersecurity tasks while matching its instruction-following performance. It is also competitive with GPT-4o-mini on cyber threat intelligence and instruction-following tasks. We envision Foundation-Sec-8B-Instruct becoming an indispensable assistant in the
We present LISA, an agentic smart contract vulnerability detection framework that combines rule-based and logic-based methods to address a broad spectrum of vulnerabilities in smart contracts. LISA leverages data from historical audit reports to learn the detection experience (without model fine-tuning), enabling it to generalize learned patterns to unseen projects and evolving threat profiles. In our evaluation, LISA significantly outperforms both LLM-based approaches and traditional static analysis tools, achieving superior coverage of vulnerability types and higher detection accuracy. Our results suggest that LISA offers a compelling solution for industry: delivering more reliable and comprehensive vulnerability detection while reducing the dependence on manual effort.
This Conceptual Design Report (CDR) presents the plans of the computing infrastructure for research at FAIR, Darmstadt, Germany. It presents the computing requirements of the various research groups, the policies for the computing and storage infrastructure, the foreseen FAIR computing model including the open data, software and services policies and architecture for the periods starting in 2028 with the "first science (plus)" phase to the modularized start version of FAIR. The overall ambition is to create a federated and centrally-orchestrated infrastructure serving the large diversity of the research lines present with sufficient scalability and flexibility to cope with future data challenges that will be present at FAIR.
Multimodal Large Language Models (MLLMs) have enabled transformative advancements across diverse applications but remain susceptible to safety threats, especially jailbreak attacks that induce harmful outputs. To systematically evaluate and improve their safety, we organized the Adversarial Testing & Large-model Alignment Safety Grand Challenge (ATLAS) 2025}. This technical report presents findings from the competition, which involved 86 teams testing MLLM vulnerabilities via adversarial image-text attacks in two phases: white-box and black-box evaluations. The competition results highlight ongoing challenges in securing MLLMs and provide valuable guidance for developing stronger defense mechanisms. The challenge establishes new benchmarks for MLLM safety evaluation and lays groundwork for advancing safer multimodal AI systems. The code and data for this challenge are openly available at https://github.com/NY1024/ATLAS_Challenge_2025.
Recently, AMD platforms have not supported offloading C++17 PSTL (StdPar) programs to the GPU. Our previous work highlights how StdPar is able to achieve good performance across NVIDIA and Intel GPU platforms. In that work, we acknowledged AMD's past effort such as HCC, which unfortunately is deprecated and does not support newer hardware platforms. Recent developments by AMD, Codeplay, and AdaptiveCpp (previously known as hipSYCL or OpenSYCL) have enabled multiple paths for StdPar programs to run on AMD GPUs. This informal report discusses our experiences and evaluation of currently available StdPar implementations for AMD GPUs. We conduct benchmarks using our suite of HPC mini-apps with ports in many heterogeneous programming models, including StdPar. We then compare the performance of StdPar, using all available StdPar compilers, to contemporary heterogeneous programming models supported on AMD GPUs: HIP, OpenCL, Thrust, Kokkos, OpenMP, SYCL. Where appropriate, we discuss issues encountered and workarounds applied during our evaluation. Finally, the StdPar model discussed in this report largely depends on Unified Shared Memory (USM) performance and very few AMD GPUs have proper
The increasing complexity and volume of financial transactions pose significant challenges to traditional fraud detection systems. This technical report investigates and compares the efficacy of classical, quantum, and quantum-hybrid machine learning models for the binary classification of fraudulent financial activities. As of our methodology, first, we develop a comprehensive behavioural feature engineering framework to transform raw transactional data into a rich, descriptive feature set. Second, we implement and evaluate a range of models on the IBM Anti-Money Laundering (AML) dataset. The classical baseline models include Logistic Regression, Decision Tree, Random Forest, and XGBoost. These are compared against three hybrid classic quantum algorithms architectures: a Quantum Support Vector Machine (QSVM), a Variational Quantum Classifier (VQC), and a Hybrid Quantum Neural Network (HQNN). Furthermore, we propose Fraud Detection for Quantum Computing (FD4QC), a practical, API-driven system architecture designed for real-world deployment, featuring a classical-first, quantum-enhanced philosophy with robust fallback mechanisms. Our results demonstrate that classical tree-based mod
Spectral Toolkit of Algorithms for Graphs (STAG) is an open-source library for efficient graph algorithms. This technical report presents the newly implemented component on locality sensitive hashing, kernel density estimation, and fast spectral clustering. The report includes a user's guide to the newly implemented algorithms, experiments and demonstrations of the new functionality, and several technical considerations behind our development.
Recently, FuseLLM introduced the concept of knowledge fusion to transfer the collective knowledge of multiple structurally varied LLMs into a target LLM through lightweight continual training. In this report, we extend the scalability and flexibility of the FuseLLM framework to realize the fusion of chat LLMs, resulting in FusionChat. FusionChat comprises two main stages. Firstly, we undertake knowledge fusion for structurally and scale-varied source LLMs to derive multiple target LLMs of identical structure and size via lightweight fine-tuning. Then, these target LLMs are merged within the parameter space, wherein we propose a novel method for determining the merging weights based on the variation ratio of parameter matrices before and after fine-tuning. We validate our approach using three prominent chat LLMs with diverse architectures and scales, namely NH2-Mixtral-8x7B, NH2-Solar-10.7B, and OpenChat-3.5-7B. Experimental results spanning various chat domains demonstrate the superiority of FusionChat-7B across a broad spectrum of chat LLMs at 7B and 34B scales, even surpassing GPT-3.5 (March) and approaching Mixtral-8x7B-Instruct.
This report relates to a study group hosted by the EPSRC funded network, Integrating data-driven BIOphysical models into REspiratory MEdicine (BIOREME), and supported by The Insigneo Institute and The Knowledge Transfer Network. The BIOREME network hosts events, including this study group, to bring together multi-disciplinary researchers, clinicians, companies and charities to catalyse research in the applications of mathematical modelling for respiratory medicine. The goal of this study group was to provide an interface between companies, clinicians, and mathematicians to develop mathematical tools to the problems presented. The study group was held at The University of Sheffield on the 17 - 20 April 2023 and was attended by 24 researchers from 13 different institutions. This report relates to a challenge presented by Arete Medical Technologies relating to impulse oscillometry (IOS), whereby a short pressure oscillation is imposed at a person's mouth during normal breathing, usually by a loudspeaker. The resulting pressure and flow rate changes can be used to the impedance of the airways, which in turn can provide proxy measurements for (patho)physiological changes in the small ai
This technical report describes the incorporation of political blogs into Pollux, the Specialised Information Service (FID) for Political Science in Germany. Considering the widespread use of political blogs in political science research, we decided to include them in the Pollux search system to enhance the available information infrastructure. We describe the crawling and analyzing of the blogs and the pipeline that integrates them into the Pollux system. To demonstrate the content of the incorporated blogs, we also provide a visualization of the topics covered by the blog posts during the first three months following integration.
In this report, we present ChuXin, an entirely open-source language model with a size of 1.6 billion parameters. Unlike the majority of works that only open-sourced the model weights and architecture, we have made everything needed to train a model available, including the training data, the training process, and the evaluation code. Our goal is to empower and strengthen the open research community, fostering transparency and enabling a new wave of innovation in the field of language modeling. Furthermore, we extend the context length to 1M tokens through lightweight continual pretraining and demonstrate strong needle-in-a-haystack retrieval performance. The weights for both models are available at Hugging Face to download and use.
Large language models are aligned to be safe, preventing users from generating harmful content like misinformation or instructions for illegal activities. However, previous work has shown that the alignment process is vulnerable to poisoning attacks. Adversaries can manipulate the safety training data to inject backdoors that act like a universal sudo command: adding the backdoor string to any prompt enables harmful responses from models that, otherwise, behave safely. Our competition, co-located at IEEE SaTML 2024, challenged participants to find universal backdoors in several large language models. This report summarizes the key findings and promising ideas for future research.
Background and Aims: This study evaluates the medical reasoning performance of large language models (LLMs) and vision language models (VLMs) in gastroenterology. Methods: We used 300 gastroenterology board exam-style multiple-choice questions, 138 of which contain images to systematically assess the impact of model configurations and parameters and prompt engineering strategies utilizing GPT-3.5. Next, we assessed the performance of proprietary and open-source LLMs (versions), including GPT (3.5, 4, 4o, 4omini), Claude (3, 3.5), Gemini (1.0), Mistral, Llama (2, 3, 3.1), Mixtral, and Phi (3), across different interfaces (web and API), computing environments (cloud and local), and model precisions (with and without quantization). Finally, we assessed accuracy using a semiautomated pipeline. Results: Among the proprietary models, GPT-4o (73.7%) and Claude3.5-Sonnet (74.0%) achieved the highest accuracy, outperforming the top open-source models: Llama3.1-405b (64%), Llama3.1-70b (58.3%), and Mixtral-8x7b (54.3%). Among the quantized open-source models, the 6-bit quantized Phi3-14b (48.7%) performed best. The scores of the quantized models were comparable to those of the full-precision