搜索结果：Eye and brain

The randomness and uniqueness of human eye patterns is a major breakthrough in the search for quicker, easier and highly reliable forms of automatic human identification. It is being used extensively in security solutions. This includes access control to physical facilities, security systems and information databases, Suspect tracking, surveillance and intrusion detection and by various Intelligence agencies through out the world. We use the advantage of human eye uniqueness to identify people and approve its validity as a biometric. . Eye detection involves first extracting the eye from a digital face image, and then encoding the unique patterns of the eye in such a way that they can be compared with pre-registered eye patterns. The eye detection system consists of an automatic segmentation system that is based on the wavelet transform, and then the Wavelet analysis is used as a pre-processor for a back propagation neural network with conjugate gradient learning. The inputs to the neural network are the wavelet maxima neighborhood coefficients of face images at a particular scale. The output of the neural network is the classification of the input into an eye or non-eye region. An

Brain tumor segmentation is crucial for diagnosis and treatment planning, yet challenges such as class imbalance and limited model generalization continue to hinder progress. This work presents a reproducible evaluation of U-Net segmentation performance on brain tumor MRI using focal loss and basic data augmentation strategies. Experiments were conducted on a publicly available MRI dataset, focusing on focal loss parameter tuning and assessing the impact of three data augmentation techniques: horizontal flip, rotation, and scaling. The U-Net with focal loss achieved a precision of 90%, comparable to state-of-the-art results. By making all code and results publicly available, this study establishes a transparent, reproducible baseline to guide future research on augmentation strategies and loss function design in brain tumor segmentation.

Reproducibility in eye-tracking research is increasingly important as researchers conduct diverse experiments and seek to validate or replicate findings. However, exact replication remains challenging due to differences in laboratory practices and experimental setups. Inconsistent stimulus presentation can yield divergent metrics from identical oculomotor behavior, yet the stimulus layer remains largely unstandardized. Existing tools often require programming expertise or depend on specific hardware vendors. We introduce VIVA Stimuli, a web-based platform for standardized eye-tracking stimulus presentation. It provides configurable task types, including fixation, smooth pursuit, cognitive load, blink, slippage, content display, and questionnaires within a unified environment. The platform supports any eye-tracking technology, including wearable and screen-based VOG trackers, LFI sensors, and EOG devices. ArUco markers enable synchronization for trackers with scene cameras, while a WebSocket architecture ensures temporal synchronization for those without. A visual experiment flow editor allows protocols to be exported and shared, enabling identical stimulus replication across labora

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred billion neurons with septillions of possible connections between them. The structure of these connections engenders an efficient hierarchical system capable of consciousness, as well as complex thoughts, feelings, and behaviors. Brain connectivity and network analyses have exploded over the last decade due to their potential in helping us understand both normal and abnormal brain function. Functional connectivity (FC) analysis examines functional associations between time series pairs in specified brain voxels or regions. Brain network analysis serves as a distinct subfield of connectivity analysis in which associations are quantified for all time series pairs to create an interconnected representation of the brain (a brain network), which allows studying its systemic properties. While connectivity analyses underlie network analyses, the subtle distinction between the two research areas has generally been overlooked in the literature, with them often b

Efficient uncertainty quantification algorithms are key to understand the propagation of uncertainty -- from uncertain input parameters to uncertain output quantities -- in high resolution mathematical models of brain physiology. Advanced Monte Carlo methods such as quasi Monte Carlo (QMC) and multilevel Monte Carlo (MLMC) have the potential to dramatically improve upon standard Monte Carlo (MC) methods, but their applicability and performance in biomedical applications is underexplored. In this paper, we design and apply QMC and MLMC methods to quantify uncertainty in a convection-diffusion model of tracer transport within the brain. We show that QMC outperforms standard MC simulations when the number of random inputs is small. MLMC considerably outperforms both QMC and standard MC methods and should therefore be preferred for brain transport models.

Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provides a deeper understanding of brain disorders at cellular level, able to consolidate a diagnosis and make the bridge between the medical image and the omics analysis. In traditional histopathology, histology slides are visually inspected, under the microscope, by trained pathologists. This process is time-consuming and labor-intensive; therefore, the emergence of Computational Pathology has triggered great hope to ease this tedious task and make it more robust. This chapter focuses on understanding the state-of-the-art machine learning techniques used to analyze whole slide images within the context of brain disorders. We present a selective set of remarkable machine learning algorithms providing discriminative approaches and quality results on brain disorders. These methodologies are applied to different tasks, such as monitoring mechanisms contributing to disease progression and patient survival rates, analyzing morphological phenotypes for classification and quantitative assessment of disease, improvin

The Scalable Brain Atlas (SBA) is a collection of web services that provide unified access to a large collection of brain atlas templates for different species. Its main component is an atlas viewer that displays brain atlas data as a stack of slices in which stereotaxic coordinates and brain regions can be selected. These are subsequently used to launch web queries to resources that require coordinates or region names as input. It supports plugins which run inside the viewer and respond when a new slice, coordinate or region is selected. It contains 20 atlas templates in six species, and plugins to compute coordinate transformations, display anatomical connectivity and fiducial points, and retrieve properties, descriptions, definitions and 3d reconstructions of brain regions. The ambition of SBA is to provide a unified representation of all publicly available brain atlases directly in the web browser, while remaining a responsive and light weight resource that specializes in atlas comparisons, searches, coordinate transformations and interactive displays.

In this Chapter we show that by considering eye movements, and in particular, the resulting sequence of gaze shifts, a stochastic process, a wide variety of tools become available for analyses and modelling beyond conventional statistical methods. Such tools encompass random walk analyses and more complex techniques borrowed from the pattern recognition and machine learning fields. After a brief, though critical, probabilistic tour of current computational models of eye movements and visual attention, we lay down the basis for gaze shift pattern analysis. To this end, the concepts of Markov Processes, the Wiener process and related random walks within the Gaussian framework of the Central Limit Theorem will be introduced. Then, we will deliberately violate fundamental assumptions of the Central Limit Theorem to elicit a larger perspective, rooted in statistical physics, for analysing and modelling eye movements in terms of anomalous, non-Gaussian, random walks and modern foraging theory. Eventually, by resorting to machine learning techniques, we discuss how the analyses of movement patterns can develop into the inference of hidden patterns of the mind: inferring the observer's tas

Large vision-language models have achieved remarkable capabilities by training on massive internet-scale data, yet a fundamental asymmetry persists: while LLMs can leverage self-supervised pretraining on abundant text and image data, the same is not true for many behavioral modalities. Video-based behavioral data -- gestures, eye movements, social signals -- remains scarce, expensive to annotate, and privacy-sensitive. A promising alternative is simulation: replace real data collection with controlled synthetic generation to produce automatically labeled data at scale. We introduce infrastructure for this paradigm applied to eye movement, a behavioral signal with applications across vision-language modeling, virtual reality, robotics, accessibility systems, and cognitive science. We present a pipeline for generating synthetic labeled eye movement video by extracting real human iris trajectories from reference videos and replaying them on a 3D eye movement simulator via headless browser automation. Applying this to the task of script-reading detection during video interviews, we release final_dataset_v1: 144 sessions (72 reading, 72 conversation) totaling 12 hours of synthetic eye m

Universal embodied intelligence demands robust generalization across heterogeneous embodiments, such as autonomous driving, robotics, and unmanned aerial vehicles (UAVs). However, existing embodied brain in training a unified model over diverse embodiments frequently triggers long-tail data, gradient interference, and catastrophic forgetting, making it notoriously difficult to balance universal generalization with domain-specific proficiency. In this report, we introduce ACE-Brain-0, a generalist foundation brain that unifies spatial reasoning, autonomous driving, and embodied manipulation within a single multimodal large language model~(MLLM). Our key insight is that spatial intelligence serves as a universal scaffold across diverse physical embodiments: although vehicles, robots, and UAVs differ drastically in morphology, they share a common need for modeling 3D mental space, making spatial cognition a natural, domain-agnostic foundation for cross-embodiment transfer. Building on this insight, we propose the Scaffold-Specialize-Reconcile~(SSR) paradigm, which first establishes a shared spatial foundation, then cultivates domain-specialized experts, and finally harmonizes them thr

Event-based eye tracking has shown great promise with the high temporal resolution and low redundancy provided by the event camera. However, the diversity and abruptness of eye movement patterns, including blinking, fixating, saccades, and smooth pursuit, pose significant challenges for eye localization. To achieve a stable event-based eye-tracking system, this paper proposes a bidirectional long-term sequence modeling and time-varying state selection mechanism to fully utilize contextual temporal information in response to the variability of eye movements. Specifically, the MambaPupil network is proposed, which consists of the multi-layer convolutional encoder to extract features from the event representations, a bidirectional Gated Recurrent Unit (GRU), and a Linear Time-Varying State Space Module (LTV-SSM), to selectively capture contextual correlation from the forward and backward temporal relationship. Furthermore, the Bina-rep is utilized as a compact event representation, and the tailor-made data augmentation, called as Event-Cutout, is proposed to enhance the model's robustness by applying spatial random masking to the event image. The evaluation on the ThreeET-plus benchma

In this study, we focus on brain tumor sequence registration between pre-operative and follow-up Magnetic Resonance Imaging (MRI) scans of brain glioma patients, in the context of Brain Tumor Sequence Registration challenge (BraTS-Reg 2022). Brain tumor registration is a fundamental requirement in brain image analysis for quantifying tumor changes. This is a challenging task due to large deformations and missing correspondences between pre-operative and follow-up scans. For this task, we adopt our recently proposed Non-Iterative Coarse-to-finE registration Networks (NICE-Net) - a deep learning-based method for coarse-to-fine registering images with large deformations. To overcome missing correspondences, we extend the NICE-Net by introducing dual deep supervision, where a deep self-supervised loss based on image similarity and a deep weakly-supervised loss based on manually annotated landmarks are deeply embedded into the NICE-Net. At the BraTS-Reg 2022, our method achieved a competitive result on the validation set (mean absolute error: 3.387) and placed 4th in the final testing phase (Score: 0.3544).

Background: Information processing in the brain requires large amounts of metabolic energy, the spatial distribution of which is highly heterogeneous reflecting complex activity patterns in the mammalian brain. Results: Here, it is found based on empirical data that, despite this heterogeneity, the volume-specific cerebral glucose metabolic rate of many different brain structures scales with brain volume with almost the same exponent around -0.15. The exception is white matter, the metabolism of which seems to scale with a standard specific exponent -1/4. The scaling exponents for the total oxygen and glucose consumptions in the brain in relation to its volume are identical and equal to $0.86\pm 0.03$, which is significantly larger than the exponents 3/4 and 2/3 suggested for whole body basal metabolism on body mass. Conclusions: These findings show explicitly that in mammals (i) volume-specific scaling exponents of the cerebral energy expenditure in different brain parts are approximately constant (except brain stem structures), and (ii) the total cerebral metabolic exponent against brain volume is greater than the much-cited Kleiber's 3/4 exponent. The neurophysiological factors

A single digital newsletter usually contains many messages (regions). Users' reading time spent on, and read level (skip/skim/read-in-detail) of each message is important for platforms to understand their users' interests, personalize their contents, and make recommendations. Based on accurate but expensive-to-collect eyetracker-recorded data, we built models that predict per-region reading time based on easy-to-collect Javascript browser tracking data. With eye-tracking, we collected 200k ground-truth datapoints on participants reading news on browsers. Then we trained machine learning and deep learning models to predict message-level reading time based on user interactions like mouse position, scrolling, and clicking. We reached 27\% percentage error in reading time estimation with a two-tower neural network based on user interactions only, against the eye-tracking ground truth data, while the heuristic baselines have around 46\% percentage error. We also discovered the benefits of replacing per-session models with per-timestamp models, and adding user pattern features. We concluded with suggestions on developing message-level reading estimation techniques based on available data

Advanced multimodal AI agents can now collaborate with users to solve challenges in the world. Yet, these emerging contextual AI systems rely on explicit communication channels between the user and system. We hypothesize that implicit communication of the user's interests and intent would reduce friction and improve user experience when collaborating with AI agents. In this work, we explore the potential of wearable eye tracking to convey signals about user attention. We measure the eye tracking signal quality requirements to effectively map gaze traces to physical objects, then conduct experiments that provide visual scanpath history as additional context when querying vision language models. Our results show that eye tracking provides high value as a user attention signal and can convey important context about the user's current task and interests, improving understanding of contextual AI agents.

A theoretical quantum brain model is proposed using a nonlinear Schroedinger wave equation. The model proposes that there exists a quantum process that mediates the collective response of a neural lattice (classical brain). The model is used to explain eye movements when tracking moving targets. Using a Recurrent Quantum Neural Network(RQNN) while simulating the quantum brain model, two very interesting phenomena are observed. First, as eye sensor data is processed in a classical brain, a wave packet is triggered in the quantum brain. This wave packet moves like a particle. Second, when the eye tracks a fixed target, this wave packet moves not in a continuous but rather in a discrete mode. This result reminds one of the saccadic movements of the eye consisting of 'jumps' and 'rests'. However, such a saccadic movement is intertwined with smooth pursuit movements when the eye has to track a dynamic trajectory. In a sense, this is the first theoretical model explaining the experimental observation reported concerning eye movements in a static scene situation. The resulting prediction is found to be very precise and efficient in comparison to classical objective modeling schemes such a

Accurate segmentation of brain tumors plays a key role in the diagnosis and treatment of brain tumor diseases. It serves as a critical technology for quantifying tumors and extracting their features. With the increasing application of deep learning methods, the computational burden has become progressively heavier. To achieve a lightweight model with good segmentation performance, this study proposes the MBDRes-U-Net model using the three-dimensional (3D) U-Net codec framework, which integrates multibranch residual blocks and fused attention into the model. The computational burden of the model is reduced by the branch strategy, which effectively uses the rich local features in multimodal images and enhances the segmentation performance of subtumor regions. Additionally, during encoding, an adaptive weighted expansion convolution layer is introduced into the multi-branch residual block, which enriches the feature expression and improves the segmentation accuracy of the model. Experiments on the Brain Tumor Segmentation (BraTS) Challenge 2018 and 2019 datasets show that the architecture could maintain a high precision of brain tumor segmentation while considerably reducing the calcu