Diagnosing dental diseases from radiographs is time-consuming and challenging due to the subtle nature of diagnostic evidence. Existing methods, which rely on object detection models designed for natural images with more distinct target patterns, struggle to detect dental diseases that present with far less visual support. To address this challenge, we propose {\bf DentalX}, a novel context-aware dental disease detection approach that leverages oral structure information to mitigate the visual ambiguity inherent in radiographs. Specifically, we introduce a structural context extraction module that learns an auxiliary task: semantic segmentation of dental anatomy. The module extracts meaningful structural context and integrates it into the primary disease detection task to enhance the detection of subtle dental diseases. Extensive experiments on a dedicated benchmark demonstrate that DentalX significantly outperforms prior methods in both tasks. This mutual benefit arises naturally during model optimization, as the correlation between the two tasks is effectively captured. Our code is available at https://github.com/zhiqin1998/DentYOLOX.
Periodontitis and dental caries are common oral diseases affecting billions globally. While observational studies suggest links between these conditions and lung cancer, causality remains uncertain. This study used two sample Mendelian randomization (MR) to explore causal relationships between dental traits (periodontitis, dental caries) and lung cancer subtypes, and to assess mediation by pulmonary function. Genetic instruments were derived from the largest available genome wide association studies, including data from 487,823 dental caries and 506,594 periodontitis cases, as well as lung cancer data from the Transdisciplinary Research of Cancer in Lung consortium. Inverse variance weighting was the main analytical method; lung function mediation was assessed using the delta method. The results showed a significant positive causal effect of dental caries on overall lung cancer and its subtypes. Specifically, a one standard deviation increase in dental caries incidence was associated with a 188.0% higher risk of squamous cell lung carcinoma (OR = 2.880, 95% CI = 1.236--6.713, p = 0.014), partially mediated by declines in forced vital capacity (FVC) and forced expiratory volume in o
Patient's understanding on forthcoming dental surgeries is required by patient-centered care and helps reduce fear and anxiety. Due to the gap of expertise between patients and dentists, conventional techniques of patient education are usually not effective for explaining surgical steps. In this paper, we present \textit{OralViewer} -- the first interactive application that enables dentist's demonstration of dental surgeries in 3D to promote patients' understanding. \textit{OralViewer} takes a single 2D panoramic dental X-ray to reconstruct patient-specific 3D teeth structures, which are then assembled with registered gum and jaw bone models for complete oral cavity modeling. During the demonstration, \textit{OralViewer} enables dentists to show surgery steps with virtual dental instruments that can animate effects on a 3D model in real-time. A technical evaluation shows our deep learning based model achieves a mean Intersection over Union (IoU) of 0.771 for 3D teeth reconstruction. A patient study with 12 participants shows \textit{OralViewer} can improve patients' understanding of surgeries. An expert study with 3 board-certified dentists further verifies the clinical validity of
Visual discrimination of clinical tissue types remains challenging, with traditional RGB imaging providing limited contrast for such tasks. Hyperspectral imaging (HSI) is a promising technology providing rich spectral information that can extend far beyond three-channel RGB imaging. Moreover, recently developed snapshot HSI cameras enable real-time imaging with significant potential for clinical applications. Despite this, the investigation into the relative performance of HSI over RGB imaging for semantic segmentation purposes has been limited, particularly in the context of medical imaging. Here we compare the performance of state-of-the-art deep learning image segmentation methods when trained on hyperspectral images, RGB images, hyperspectral pixels (minus spatial context), and RGB pixels (disregarding spatial context). To achieve this, we employ the recently released Oral and Dental Spectral Image Database (ODSI-DB), which consists of 215 manually segmented dental reflectance spectral images with 35 different classes across 30 human subjects. The recent development of snapshot HSI cameras has made real-time clinical HSI a distinct possibility, though successful application req
Oral diseases such as periodontal (gum) diseases and dental caries (cavities) affect billions of people across the world today. However, previous state-of-the-art models have relied on X-ray images to detect oral diseases, making them inaccessible to remote monitoring, developing countries, and telemedicine. To combat this overuse of X-ray imagery, we propose a lightweight machine learning model capable of detecting calculus (also known as hardened plaque or tartar) in RGB images while running efficiently on low-end devices. The model, a modified MobileNetV3-Small neural network transfer learned from ImageNet, achieved an accuracy of 72.73% (which is comparable to state-of-the-art solutions) while still being able to run on mobile devices due to its reduced memory requirements and processing times. A ResNet34-based model was also constructed and achieved an accuracy of 81.82%. Both of these models were tested on a mobile app, demonstrating their potential to limit the number of serious oral disease cases as their predictions can help patients schedule appointments earlier without the need to go to the clinic.
A fundamental challenge for modern economics is to understand what happens when actors in an economy are replaced with algorithms. Like rationality has enabled understanding of outcomes of classical economic actors, no-regret can enable the understanding of outcomes of algorithmic actors. This review article covers the classical computer science literature on no-regret algorithms to provide a foundation for an overview of the latest economics research on no-regret algorithms, focusing on the emerging topics of manipulation, statistical inference, and algorithmic collusion.
Analyzing authors' sentiments in texts as a technique for identifying text polarity can be practical and useful in various fields, including medicine and dentistry. Currently, due to factors such as patients' limited knowledge about their condition, difficulties in accessing specialist doctors, or fear of illness, particularly in pandemic conditions, there might be a delay between receiving a radiology report and consulting a doctor. In some cases, this delay can pose significant risks to the patient, making timely decision-making crucial. Having an automatic system that can inform patients about the deterioration of their condition by analyzing the text of radiology reports could greatly impact timely decision-making. In this study, a dataset comprising 1,134 cone-beam computed tomography (CBCT) photo reports was collected from the Shiraz University of Medical Sciences. Each case was examined, and an expert labeled a severity level for the patient's condition on each document. After preprocessing all the text data, a deep learning model based on Convolutional Neural Network (CNN) and Long Short-Term Memory (LSTM) network architecture, known as CNN-LSTM, was developed to detect the
Panoramic X-ray (PX) provides a 2D picture of the patient's mouth in a panoramic view to help dentists observe the invisible disease inside the gum. However, it provides limited 2D information compared with cone-beam computed tomography (CBCT), another dental imaging method that generates a 3D picture of the oral cavity but with more radiation dose and a higher price. Consequently, it is of great interest to reconstruct the 3D structure from a 2D X-ray image, which can greatly explore the application of X-ray imaging in dental surgeries. In this paper, we propose a framework, named Oral-3D, to reconstruct the 3D oral cavity from a single PX image and prior information of the dental arch. Specifically, we first train a generative model to learn the cross-dimension transformation from 2D to 3D. Then we restore the shape of the oral cavity with a deformation module with the dental arch curve, which can be obtained simply by taking a photo of the patient's mouth. To be noted, Oral-3D can restore both the density of bony tissues and the curved mandible surface. Experimental results show that Oral-3D can efficiently and effectively reconstruct the 3D oral structure and show critical info
The mouth, often regarded as a window to the internal state of the body, plays an important role in reflecting one's overall health. Poor oral hygiene has far-reaching consequences, contributing to severe conditions like heart disease, cancer, and diabetes, while inadequate care leads to discomfort, pain, and costly treatments. Federated Learning (FL) for object detection can be utilized for this use case due to the sensitivity of the oral image data of the patients. FL ensures data privacy by storing the images used for object detection on the local device and trains the model on the edge. The updated weights are federated to a central server where all the collected weights are updated via The Federated Averaging algorithm. Finally, we have developed a mobile app named OralH which provides user-friendly solutions, allowing people to conduct self-assessments through mouth scans and providing quick oral health insights. Upon detection of the issues, the application alerts the user about potential oral health concerns or diseases and provides details about dental clinics in the user's locality. Designed as a Progressive Web Application (PWA), the platform ensures ubiquitous access, c
Dental informatics is a rapidly evolving field that combines dentistry with information technology to improve oral health care delivery, research, and education. Electronic health records (EHRs), telehealth, digital imaging, and other digital tools have revolutionised how dental professionals diagnose, treat, and manage oral health conditions. In this review article, we will explore dental informatics's current trends and future directions, focusing on its impact on clinical practice, research, and education. We will also discuss the challenges and opportunities associated with implementing dental informatics and highlight fundamental research studies and innovations in the field.
Nowadays, more effective control of hand hygiene (HH) by healthcare teams has become essential. HH control is crucial to prevent cross-contamination and healthcare-associated infections (HAI), according to Brazilian regulatory standards and WHO guidelines. The lack of widespread technology to measure acceptable hygiene rates within hospital environments leads to the practice of a manual sample audit reading, requiring more time for decision making. Thus, the present study addresses the lack of automation technologies for HH, aiming to record, measure, and provide data for internal audits in hospitals. This article introduces an embedded system for HH control and recording, comprising low-cost hardware architecture with IoT connectivity and online monitoring. Results with practical evaluation in a real hospital setting for 3 hours demonstrated the system's effectiveness in recording HH indices.
The rise of foundation models has driven the emergence of AI supply chains, where upstream foundation model providers offer fine-tuning and inference services to downstream firms developing domain-specific applications. Downstream firms pay providers to use their computing infrastructure to fine-tune models with proprietary data, creating a co-creation dynamic that enhances model quality. Amid concerns that foundation model providers and downstream firms may capture excessive consumer surplus, along with increasing regulatory measures, this study employs a game-theoretic model involving a provider and two competing downstream firms to analyze how policy interventions affect consumer surplus in the AI supply chain. Our analysis shows that policies promoting price competition in downstream markets (i.e., pro-price-competitive policies) boost consumer surplus only when compute or data preprocessing costs are high, while compute subsidies are effective only when these costs are low, suggesting these policies complement each other. In contrast, policies promoting quality competition in downstream markets (i.e., pro-quality-competitive policies) always improve consumer surplus. We also f
Financial and economic history is strewn with bubbles and crashes, booms and busts, crises and upheavals of all sorts. Understanding the origin of these events is arguably one of the most important problems in economic theory: are economies intrinsically unstable, and can one ``stabilize unstable economies''? In this review I argue, from a physicist's vantage point, that the concept of equilibrium -- so central to mainstream economic thinking -- is likely to be the exception rather than the rule in large, complex, interacting systems. Drawing on a series of stylized ``toy'' models, I show how excess volatility, endogenous crises and crashes, inflation swells and persistent inequalities can all emerge naturally from genuinely out-of-equilibrium dynamics, without invoking large exogenous shocks. Three generic mechanisms recur throughout: trapping in a multiplicity of history-dependent equilibria; the impossibility of dynamically reaching equilibrium, leading to oscillations and chaos; and the spontaneous evolution towards fragile, marginally stable states -- the self-organized criticality paradigm. I stress that these are phenomenological scenarios rather than calibrated theories: th
This paper establishes the theoretical and practical foundations for using Large Language Models (LLMs) as measurement instruments for latent economic variables -- specifically variables that describe the cognitive content of occupational tasks at a level of granularity not achievable with existing survey instruments. I formalize four conditions under which LLM-generated scores constitute valid instruments: semantic exogeneity, construct relevance, monotonicity, and model invariance. I then apply this framework to the Augmented Human Capital Index (AHC_o), constructed from 18,796 O*NET task statements scored by Claude Haiku 4.5, and validated against six existing AI exposure indices. The index shows strong convergent validity (r = 0.85 with Eloundou GPT-gamma, r = 0.79 with Felten AIOE) and discriminant validity. Principal component analysis confirms that AI-related occupational measures span two distinct dimensions -- augmentation and substitution. Inter-rater reliability across two LLM models (n = 3,666 paired scores) yields Pearson r = 0.76 and Krippendorff's alpha = 0.71. Prompt sensitivity analysis across four alternative framings shows that task-level rankings are robust. Obv
This paper presents a novel quantitative approach for comparative economic studies, addressing limitations in current classification methods. Conventional approaches in comparative economics often rely on ad hoc and categorical classifications, leading to subjective judgments and disregarding the continuous nature of the spectrum of economic systems. These can result in subjectivity and significant information loss, particularly for countries with systems near categorical borders. To overcome these shortcomings, the present paper proposes distance-based indices for objective categorization, considering economic foundations and using hard data. Accordingly, the paper introduces institutional similarity indices--Capitalism Similarity Index (CapSI), Communism Similarity Index (ComSI), and Socialism Similarity Index (SocSI)-which reflect countries' positions along the economic system continuum. These indices adhere to mathematical rigor and are grounded in the mathematical fields of real analysis, metric spaces, and distance functions. By classifying 135 countries and creating GIS maps, the practical applicability of the proposed approach is demonstrated. Results show a high explanator
Background: Dental caries diagnosis requires the manual inspection of diagnostic bitewing images of the patient, followed by a visual inspection and probing of the identified dental pieces with potential lesions. Yet the use of artificial intelligence, and in particular deep-learning, has the potential to aid in the diagnosis by providing a quick and informative analysis of the bitewing images. Methods: A dataset of 13,887 bitewings from the HUNT4 Oral Health Study were annotated individually by six different experts, and used to train three different object detection deep-learning architectures: RetinaNet (ResNet50), YOLOv5 (M size), and EfficientDet (D0 and D1 sizes). A consensus dataset of 197 images, annotated jointly by the same six dentist, was used for evaluation. A five-fold cross validation scheme was used to evaluate the performance of the AI models. Results: he trained models show an increase in average precision and F1-score, and decrease of false negative rate, with respect to the dental clinicians. When compared against the dental clinicians, the YOLOv5 model shows the largest improvement, reporting 0.647 mean average precision, 0.548 mean F1-score, and 0.149 mean fal
Learning about diagnostic features and related clinical information from dental radiographs is important for dental research. However, the lack of expert-annotated data and convenient search tools poses challenges. Our primary objective is to design a search tool that uses a user's query for oral-related research. The proposed framework, Contrastive LAnguage Image REtrieval Search for dental research, Dental CLAIRES, utilizes periapical radiographs and associated clinical details such as periodontal diagnosis, demographic information to retrieve the best-matched images based on the text query. We applied a contrastive representation learning method to find images described by the user's text by maximizing the similarity score of positive pairs (true pairs) and minimizing the score of negative pairs (random pairs). Our model achieved a hit@3 ratio of 96% and a Mean Reciprocal Rank (MRR) of 0.82. We also designed a graphical user interface that allows researchers to verify the model's performance with interactions.
Dental disease is one of the most common chronic diseases despite being largely preventable. However, professional advice on optimal oral hygiene practices is often forgotten or abandoned by patients. Therefore patients may benefit from timely and personalized encouragement to engage in oral self-care behaviors. In this paper, we develop an online reinforcement learning (RL) algorithm for use in optimizing the delivery of mobile-based prompts to encourage oral hygiene behaviors. One of the main challenges in developing such an algorithm is ensuring that the algorithm considers the impact of the current action on the effectiveness of future actions (i.e., delayed effects), especially when the algorithm has been made simple in order to run stably and autonomously in a constrained, real-world setting (i.e., highly noisy, sparse data). We address this challenge by designing a quality reward which maximizes the desired health outcome (i.e., high-quality brushing) while minimizing user burden. We also highlight a procedure for optimizing the hyperparameters of the reward by building a simulation environment test bed and evaluating candidates using the test bed. The RL algorithm discussed
The recent ongoing coronavirus pandemic highlights the importance of hand hygiene practices in our daily lives, with governments and worldwide health authorities promoting good hand hygiene practices. More than one million cases of hospital-acquired infections occur in Europe annually. Hand hygiene compliance may reduce the risk of transmission by reducing the number of infections as well as healthcare expenditures. In this paper, the World Health Organization, hand hygiene gestures are recorded and analyzed with the construction of an aluminum frame, placed at the laboratory sink. The hand hygiene gestures are recorded for thirty participants after conducting a training session about hand hygiene gestures demonstration. The video recordings are converted into image files and are organized into six different hand hygiene classes. The Resnet50 framework selection for the classification of multiclass hand hygiene stages. The model is trained with the first set of classes; Fingers Interlaced, P2PFingers Interlaced, and Rotational Rub for 25 epochs. An accuracy of 44 percent for the first set of experiments with a loss score greater than 1.5 in the validation set is achieved. The train
Examining the economic impact of noise pollution from a lens of household is a burgeoning field in the study of environmental sustainability. Economics studies cover the source, measure, consequence of noise pollution, as well as the econometric methods used to identify the causal impact of noise pollution on socioeconomic welfare. There are broadly four major noise origins along with the industrial growth and urban development, which are airport, railway, urban traffic, and neighborhood. Four general kinds of measures or data sources are used in economics studies to capture the noise variations, namely, proximity to noise origins, real-time noise monitor records, household surveys, and administrative records on noise complaints. The socioeconomic consequences of noise pollution span from physical or mental health to happiness, violence and suicide, housing market capitalization, and inequality. In economics studies, generally three types of econometric methods are used to identify causal impact of noise pollution on the household's welfare, which are instrumental variable estimation, difference-in-difference estimation, randomized and quasi-natural experiments. The causal impact o