Electronic health records (EHRs) provide comprehensive patient data which could be better used to enhance informed decision-making, resource allocation, and coordinated care, thereby optimising healthcare delivery. However, in mental healthcare, critical information, such as on risk factors, precipitants, and treatment responses, is often embedded in unstructured text, limiting the ability to automate at scale measures to identify and prioritise local populations and patients, which potentially hinders timely prevention and intervention. We describe the development and proof-of-concept implementation of VIEWER, a clinical informatics platform designed to enhance direct patient care and population health management by improving the accessibility and usability of EHR data. We further outline strategies that were employed in this work to foster informatics innovation through interdisciplinary and cross-organisational collaboration to support integrated, personalised care, and detail how these advancements were piloted and implemented within a large UK mental health National Health Service Foundation Trust to improve patient outcomes at an individual patient, clinician, clinical team,
Personal Health Informatics (PHI), which leverages digital tools and information systems to support health assessment and self-care, promises more proactive, user-centered care, yet adoption and meaningful utilization barriers in India remain underexplored. Through a sequential mixed-methods study in urban India (Initial survey (n=87) and semi-structured interviews (n=22), follow-up survey = 116, and co-design workshops (n=6)), we surface practices, perceptions, and behaviors to identify ways PHI can be better utilized for proactive care in the Indian context. We find that PHI is valued for monitoring and enabling collective care; however, its adoption is constrained by low health and technology literacy, usability and integration issues, fragmented and costly technology ecosystems, and mistrust of digital health platforms. From triangulated evidence, we derive concrete design requirements, including user-controlled sharing, accessible analytics, and verifiable health information, and present a culturally grounded design vision for an integrated platform for collective care through design and evaluation of a figma prototype. The prototype evaluation provides further directions for
The growing demand for home healthcare calls for tools that can support care delivery. In this study, we explore automatic health assessment from voice using real-world home care visit data, leveraging the diverse patient information it contains. First, we utilize Large Language Models (LLMs) to integrate Subjective, Objective, Assessment, and Plan (SOAP) notes derived from unstructured audio transcripts and structured vital signs into a holistic illness score that reflects a patient's overall health. This compact representation facilitates cross-visit health status comparisons and downstream analysis. Next, we design a multi-stage preprocessing pipeline to extract short speech segments from target speakers in home care recordings for acoustic analysis. We then employ an Audio Language Model (ALM) to produce plain-language descriptions of vocal biomarkers and examine their association with individuals' health status. Our experimental results benchmark both commercial and open-source LLMs in estimating illness scores, demonstrating their alignment with actual clinical outcomes, and revealing that SOAP notes are substantially more informative than vital signs. Building on the illness
Demand for health care is constantly increasing due to the ongoing demographic change, while at the same time health service providers face difficulties in finding skilled personnel. This creates pressure on health care systems around the world, such that the efficient, nationwide provision of primary health care has become one of society's greatest challenges. Due to the complexity of health care systems, unforeseen future events, and a frequent lack of data, analyzing and optimizing the performance of health care systems means tackling a wicked problem. To support this task for primary care, this paper introduces the hybrid agent-based simulation model SiM-Care. SiM-Care models the interactions of patients and primary care physicians on an individual level. By tracking agent interactions, it enables modelers to assess multiple key indicators such as patient waiting times and physician utilization. Based on these indicators, primary care systems can be assessed and compared. Moreover, changes in the infrastructure, patient behavior, and service design can be directly evaluated. To showcase the opportunities offered by SiM-Care and aid model validation, we present a case study for
This review underscores the vital role of interoperability in digital health, advocating for a standardized framework. It focuses on implementing a Fast Healthcare Interoperability Resources (FHIR) server, addressing technical, semantic, and process challenges. FHIR's adaptability ensures uniformity within Primary Care Health Information Systems, fostering interoperability. Patient data management complexities highlight the pivotal role of semantic interoperability in seamless patient care. FHIR standards enhance these efforts, offering multiple pathways for data search. The ADR-guided FHIR server implementation systematically addresses challenges related to patient identity, biometrics, and data security. The detailed development phases emphasize architecture, API integration, and security. The concluding stages incorporate forward-looking approaches, including HHIMS Synthetic Dataset testing. Envisioning FHIR integration as transformative, it anticipates a responsive healthcare environment aligned with the evolving digital health landscape, ensuring comprehensive, dynamic, and interconnected systems for efficient data exchange and access.
Artificial intelligence (AI)-enabled digital interventions, including Generative AI (GenAI) and Human-Centered AI (HCAI), are increasingly used to expand access to digital psychiatry and mental health care. This PRISMA-ScR scoping review maps the landscape of AI-driven mental health (mHealth) technologies across five critical phases: pre-treatment (screening/triage), treatment (therapeutic support), post-treatment (remote patient monitoring), clinical education, and population-level prevention. We synthesized 36 empirical studies implemented through early 2024, focusing on Large Language Models (LLMs), machine learning (ML) models, and autonomous conversational agents. Key use cases involve referral triage, empathic communication enhancement, and AI-assisted psychotherapy delivered via chatbots and voice agents. While benefits include reduced wait times and increased patient engagement, we address recurring challenges like algorithmic bias, data privacy, and human-AI collaboration barriers. By introducing a novel four-pillar framework, this review provides a comprehensive roadmap for AI-augmented mental health care, offering actionable insights for researchers, clinicians, and poli
Abundant evidence has tracked the labour market and health assimilation of immigrants, including static analyses of differences in how foreign-born and native-born residents consume health care services. However, we know much less about how migrants' patterns of health care usage evolve with time of residence, especially in countries providing universal or quasi-universal coverage. We investigate this process in Spain by combining all the available waves of the local health survey, which allows us to separately identify period, cohort, and assimilation effects. We find that the evidence of health assimilation is limited and solely applies to migrant females' visits to general practitioners. Nevertheless, the differential effects of ageing on health care use between foreign-born and native-born populations contributes to the convergence of utilisation patterns in most health services after 20 years in Spain. Substantial heterogeneity over time and by region of origin both suggest that studies modelling future welfare state finances would benefit from a more thorough assessment of migration.
Healthcare has witnessed an increased digitalization in the post-COVID world. Technologies such as the medical internet of things and wearable devices are generating a plethora of data available on the cloud anytime from anywhere. This data can be analyzed using advanced artificial intelligence techniques for diagnosis, prognosis, or even treatment of disease. This advancement comes with a major risk to protecting and securing protected health information (PHI). The prevailing regulations for preserving PHI are neither comprehensive nor easy to implement. The study first identifies twenty activities crucial for privacy and security, then categorizes them into five homogeneous categories namely: $\complement_1$ (Policy and Compliance Management), $\complement_2$ (Employee Training and Awareness), $\complement_3$ (Data Protection and Privacy Control), $\complement_4$ (Monitoring and Response), and $\complement_5$ (Technology and Infrastructure Security) and prioritizes these categories to provide a framework for the implementation of privacy and security in a wise manner. The framework utilized the Delphi Method to identify activities, criteria for categorization, and prioritization.
Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come great optimism regarding their promise to create novel, large-scale solutions to support mental health. Despite their nascence, LLMs have already been applied to mental health related tasks. In this paper, we summarize the extant literature on efforts to use LLMs to provide mental health education, assessment, and intervention and highlight key opportunities for positive impact in each area. We then highlight risks associated with LLMs' application to mental health and encourage the adoption of strategies to mitigate these risks. The urgent need for mental health support must be balanced with responsible development, testing, and deployment of mental health LLMs. It is especially critical to ensure that mental health LLMs are fine-tuned for mental health, enhance mental health equity, and adhere to ethical standards and that people, including those with lived experience with mental health concerns, are involved in all stages from development through
Citation network analysis has become one of methods to study how scientific knowledge flows from one domain to another. Health informatics is a multidisciplinary field that includes social science, software engineering, behavioral science, medical science and others. In this study, we perform an analysis of citation statistics from health informatics journals using data set extracted from CrossRef. For each health informatics journal, we extract the number of citations from/to studies related to computer science, medicine/clinical medicine and other fields, including the number of self-citations from the health informatics journal. With a similar number of articles used in our analysis, we show that the Journal of the American Medical Informatics Association (JAMIA) has more in-citations than the Journal of Medical Internet Research (JMIR); while JMIR has a higher number of out-citations and self-citations. We also show that JMIR cites more articles from health informatics journals and medicine related journals. In addition, the Journal of Medical Systems (JMS) cites more articles from computer science journals compared with other health informatics journals included in our analysi
The health needs of those living in resource-limited settings are a vastly overlooked and understudied area in the intersection of machine learning (ML) and health care. While the use of ML in health care is more recently popularized over the last few years from the advancement of deep learning, low-and-middle income countries (LMICs) have already been undergoing a digital transformation of their own in health care over the last decade, leapfrogging milestones due to the adoption of mobile health (mHealth). With the introduction of new technologies, it is common to start afresh with a top-down approach, and implement these technologies in isolation, leading to lack of use and a waste of resources. In this paper, we outline the necessary considerations both from the perspective of current gaps in research, as well as from the lived experiences of health care professionals in resource-limited settings. We also outline briefly several key components of successful implementation and deployment of technologies within health systems in LMICs, including technical and cultural considerations in the development process relevant to the building of machine learning solutions. We then draw on
Objectives: The article provides an overview of current trends in personal sensor, signal and imaging informatics, that are based on emerging mobile computing and communications technologies enclosed in a smartphone and enabling the provision of personal, pervasive health informatics services. Methods: The article reviews examples of these trends from the PubMed and Google scholar literature search engines, which, by no means claim to be complete, as the field is evolving and some recent advances may not be documented yet. Results: There exist critical technological advances in the surveyed smartphone technologies, employed in provision and improvement of diagnosis, acute and chronic treatment and rehabilitation health services, as well as in education and training of healthcare practitioners. However, the most emerging trend relates to a routine application of these technologies in a prevention/wellness sector, helping its users in self-care to stay healthy. Conclusions: Smartphone-based personal health informatics services exist, but still have a long way to go to become an everyday, personalized healthcare-provisioning tool in the medical field and in a clinical practice. Key ma
Mobile health has the potential to revolutionize health care delivery and patient engagement. In this work, we discuss how integrating Artificial Intelligence into digital health applications-focused on supply chain, patient management, and capacity building, among other use cases-can improve the health system and public health performance. We present an Artificial Intelligence and Reinforcement Learning platform that allows the delivery of adaptive interventions whose impact can be optimized through experimentation and real-time monitoring. The system can integrate multiple data sources and digital health applications. The flexibility of this platform to connect to various mobile health applications and digital devices and send personalized recommendations based on past data and predictions can significantly improve the impact of digital tools on health system outcomes. The potential for resource-poor settings, where the impact of this approach on health outcomes could be more decisive, is discussed specifically. This framework is, however, similarly applicable to improving efficiency in health systems where scarcity is not an issue.
Electronic Health Record (EHR) has become an essential tool in the healthcare ecosystem, providing authorized clinicians with patients' health-related information for better treatment. While most developed countries are taking advantage of EHRs to improve their healthcare system, it remains challenging in developing countries to support clinical decision-making and public health using a computerized patient healthcare information system. This paper proposes a novel EHR architecture suitable for developing countries--an architecture that fosters inclusion and provides solutions tailored to all social classes and socioeconomic statuses. Our architecture foresees an internet-free (offline) solution to allow medical transactions between healthcare organizations, and the storage of EHRs in geographically underserved and rural areas. Moreover, we discuss how artificial intelligence can leverage anonymous health-related information to enable better public health policy and surveillance.
The connection between the design and delivery of health care services using information technology is known as health informatics. It involves data usage, validation, and transfer of an integrated medical analysis using neural networks of multi-layer deep learning techniques to analyze complex data. For instance, Google incorporated ''DeepMind'' health mobile tool that integrates \& leverage medical data needed to enhance professional healthcare delivery to patients. Moorfield Eye Hospital London introduced DeepMind Research Algorithms with dozens of retinal scans attributes while DeepMind UCL handled the identification of cancerous tissues using CT \& MRI Scan tools. Atomise analyzed drugs and chemicals with Deep Learning Neural Networks to identify accurate pre-clinical prescriptions. Health informatics makes medical care intelligent, interactive, cost-effective, and accessible; especially with DL application tools for detecting the actual cause of diseases. The extensive use of neural network tools leads to the expansion of different medical disciplines which mitigates data complexity and enhances 3-4D overlap images using target point label data detectors that support
Large AI models, or foundation models, are models recently emerging with massive scales both parameter-wise and data-wise, the magnitudes of which can reach beyond billions. Once pretrained, large AI models demonstrate impressive performance in various downstream tasks. A prime example is ChatGPT, whose capability has compelled people's imagination about the far-reaching influence that large AI models can have and their potential to transform different domains of our lives. In health informatics, the advent of large AI models has brought new paradigms for the design of methodologies. The scale of multi-modal data in the biomedical and health domain has been ever-expanding especially since the community embraced the era of deep learning, which provides the ground to develop, validate, and advance large AI models for breakthroughs in health-related areas. This article presents a comprehensive review of large AI models, from background to their applications. We identify seven key sectors in which large AI models are applicable and might have substantial influence, including 1) bioinformatics; 2) medical diagnosis; 3) medical imaging; 4) medical informatics; 5) medical education; 6) pu
Missing data, inaccuracies in medication lists, and recording delays in electronic health records (EHR) are major limitations for target trial emulation (TTE), the process by which EHR data are used to retrospectively emulate a randomized control trial. EHR TTE relies on recorded data that proxy true drug exposures and outcomes. We investigate the under-utilized criterion that a patient has indications of primary care provider (PCP) encounters within the EHR. Such patients tend to have more records overall and a greater proportion of the types of encounters that materialize comprehensive and up-to-date records. We examine the impact of including a PCP feature in the TTE model or as an eligibility criterion for cohort selection, contrasted with ignoring it altogether. To that end, we compare the estimated effects of two first line antidiabetic drug classes on the onset of Alzheimer's Disease and Related Dementias (ADRD). We find that the estimated treatment effect is sensitive to the consideration of a PCP feature, particularly when used as an eligibility criterion. Our work suggests that this PCP feature should be further researched.
Industry 4.0 in health care has evolved drastically over the past century. In fact, it is evolving every day, with new tools and strategies being developed by physicians and researchers alike. Health care and technology have been intertwined together with the advancement of cloud computing and big data. This study aims to analyze the impact of industry 4.0 in health care systems. To do so, a systematic literature review was carried out considering peer-reviewed articles extracted from the two popular databases: Scopus and Web of Science (WoS). PRISMA statement 2015 was used to include and exclude that data. At first, a bibliometric analysis was carried out using 346 articles considering the following factors: publication by year, journal, authors, countries, institutions, authors' keywords, and citations. Finally, qualitative analysis was carried out based on selected 32 articles considering the following factors: a conceptual framework, schedule problems, security, COVID-19, digital supply chain, and blockchain technology. Study finding suggests that during the onset of COVID-19, health care and industry 4.0 has been merged and evolved jointly, considering various crisis such as d
The distribution of health care payments to insurance plans has substantial consequences for social policy. Risk adjustment formulas predict spending in health insurance markets in order to provide fair benefits and health care coverage for all enrollees, regardless of their health status. Unfortunately, current risk adjustment formulas are known to underpredict spending for specific groups of enrollees leading to undercompensated payments to health insurers. This incentivizes insurers to design their plans such that individuals in undercompensated groups will be less likely to enroll, impacting access to health care for these groups. To improve risk adjustment formulas for undercompensated groups, we expand on concepts from the statistics, computer science, and health economics literature to develop new fair regression methods for continuous outcomes by building fairness considerations directly into the objective function. We additionally propose a novel measure of fairness while asserting that a suite of metrics is necessary in order to evaluate risk adjustment formulas more fully. Our data application using the IBM MarketScan Research Databases and simulation studies demonstrate
This study is mainly aimed at evaluating the effectiveness of current health care systems of several representative countries and improving that of the US. To achieve these goals, a people-oriented non-linear evaluation model is designed. It comprises one major evaluation metric and four minor metrics. The major metric is constituted by combining possible factors that most significantly determine or affect the life expectancy of people in this country. The four minor metrics evaluate less important aspects of health care systems and are subordinate to the major one. The authors rank some of the health care systems in the world according to the major metric and detect problems in them with the help of minor ones. It is concluded that the health care system of Sweden scores higher than the US and Chinese system scores lower than that of the US. Especially, the health care system of US lags behind a little bit compared with its economic power. At last, it is reasonable for the American government to optimize the arrangement of funding base on the result of goal programming model.