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Educational Engagement Modules (EEMs) are teaching materials for educators and students that facilitate a deeper understanding of key epidemiological methods and concepts. Each EEM poses a series of questions using a recently published paper in Annals to further understanding of a specific study design or epidemiological concept and to encourage critical thinking and careful evaluation. This EEM focuses on information bias in the following article: Ranker LR, Katz-Wise SL, Gordon AR, Korkodilos R, Xuan Z, Nelson KM. Sexual orientation identity and attraction changes among youth: prospective versus retrospective measurement. Ann Epidemiol. 2025 Dec;112:8-14. doi:10.1016/j.annepidem.2025.10.006. Epub 2025 Oct 6. PMID: 41061832 [1].
The purpose of this analysis was to systematically map the intellectual structure, thematic evolution, and collaborative patterns of research in the field of deep-breathing exercises (DBEs). A comprehensive bibliometric analysis combined with Latent Dirichlet Allocation-based topic modeling was conducted using publications retrieved from Web of Science, Scopus, and PubMed. A total of 2,017 publications published between 1940 and 2024 were included. Bibliometric indicators were used to examine publication trends, leading journals, authors, countries, and collaboration networks, while Latent Dirichlet Allocation was applied to identify dominant research themes. The annual number of publications increased steadily over time, with a marked rise after 2011 and a peak observed in 2020. The most productive countries were the United States, Italy, and Germany, while the leading journals included Chest and The Annals of Thoracic Surgery. Collaboration analyses revealed limited international and interinstitutional research networks. Topic modeling identified three major thematic clusters: (1) education and training-focused DBE interventions, (2) application of DBE following cardiac and thoracic surgery, and (3) postoperative complication prevention and rehabilitation. This bibliometric and topic modeling analysis provides a structured overview of the intellectual organization and thematic evolution of DBE research in surgical and perioperative care. Rather than evaluating clinical effectiveness, the findings highlight prevailing research priorities, collaboration gaps, and underexplored areas. These insights may support perianesthesia nursing by informing future research agendas, encouraging interdisciplinary collaboration, and guiding the strategic development of DBE-related studies.
Perioperative care for oesophageal cancer (OC) patients is crucial in optimising surgical outcomes and improving recovery. This study aims to conduct a bibliometric analysis to explore the frontier trends in perioperative care for OC patients. Publications from 1997 to 2024 were retrieved from the Web of Science Core Collection database. The bibliometric analysis utilised VOSviewer, CiteSpace and the R package 'bibliometrix' to visualise collaborations, keyword co-occurrences and emerging research trends. A total of 816 publications were identified, with an annual growth rate of 9%. The United States led in publication volume (206, 25%), followed by Japan (173, 21%) and China (128, 16%). University of Amsterdam emerged as the most prolific institution, contributing significantly to the field in publications (68). Hofstetter Wayne stood out with publications and citations of 16 and 1751. The Diseases of the Esophagus and Annals of Surgery were the top-ranked journal, with the highest publications (68) and citations (2041). The co-occurrence network revealed four major clusters, including epidemiology, chemoradiation therapy, surgical therapy and complications. Keyword burst analysis emphasised terms such as 'postoperative complications', 'multicenter' and 'open label'. This bibliometric analysis provides a comprehensive overview of the research developments in perioperative care for OC patients. It highlighted key trends and emerging research frontiers, including perioperative fluid management in OC patients. Future trends emphasise open-label clinical trials and the development of multimodal treatment strategies to improve survival outcomes. These findings offer valuable insights for advancing clinical and scientific progress in the field.
Religiosity and spirituality are central to the lives of Filipinos, yet limited research has examined their role in well-being. Although traditionally viewed as distinct constructs, religiosity and spirituality are deeply intertwined among Filipinos, with religious practice serving as a pathway for cultivating spiritual experience. Given the established role of spiritual experience in well-being, daily spiritual experience may represent a key mechanism through which religious practice translates into greater life satisfaction, yet research directly examining this mediating pathway remains limited. A further concern is that widely used spirituality measures, including the Daily Spiritual Experience Scale (DSES; Underwood and Teresi, Annals of Behavioral Medicine 24:22-33, 2002), have been criticized for containing items that overlap with mental and social health outcomes, raising tautological questions about observed associations. The present study addressed both concerns. A theistic 5-item version of the DSES was validated among Filipino Catholics and demonstrated superior psychometric fit over the full 13-item version. Using this validated measure, the study examined whether private religious practices predict life satisfaction and whether daily spiritual experience mediates this relationship in a sample of 1,189 Filipino Catholics (Mage = 18.86, SD = 4.67). Results showed that private religious practices positively predicted life satisfaction, with daily spiritual experience serving as a significant mediator. These findings suggest that private religious practices enhance life satisfaction by fostering an experiential sense of closeness to God that is distinct from general psychological well-being, while also providing a psychometrically robust measure of theistic spirituality for future research among the Filipino faithful.
Neoadjuvant therapy (NAT) is increasingly being applied in gastric cancer (GC) and is recognized by international guidelines. This study aims to analyze the current status, hotspots, and research trends of NAT in GC through bibliometrics. Relevant publications were collected from Web of Science (SCI-Expanded) and PubMed. We utilized Citespace to analyze countries, institutions, and keywords, and employed Vosviewer to examine authors and their co-cited authors, as well as journals and their co-cited journals. The analysis encompassed 2666 documents. The overall number of publications showed an upward trend. The top-producing countries, institutions, authors, and journals in this field were: The People's Republic of China and Chinese Academy of Medical Sciences - Peking Union Medical College, Huang, Changming, and Annals of Surgical Oncology. The most frequently cited author and journal are Al-batran and the Journal of Clinical Oncology, respectively. Key research areas in this field include: diverse NAT strategies; open-label trials and survival outcomes; and technology empowerment. Potential future research trends encompass: deep learning applications; immune checkpoint inhibitors; nivolumab; and immunotherapy. We used bibliometrics to conduct a visual analysis of the application of NAT in GC. Research hotspots include diverse NAT strategies, open-label trials and survival outcomes, and technology empowerment.
This article aimed to articulate the most important unmet scientific needs in rheumatology. At the 25th Advances in Targeted Therapies (ATT) meeting, over 100 investigators joined 6 disease-focused breakout groups (rheumatoid arthritis [RA], psoriatic arthritis [PsA], axial spondyloarthritis [axSpA], systemic lupus erythematous [SLE], systemic sclerosis [SSc], and osteoarthritis [OA]). Each group, led by a facilitator and rapporteur, mapped (i) key unmet needs, (ii) promising mechanistic or therapeutic approaches, and (iii) near-term priorities for research and trials. This report synthesises the consensus highlights. Six disease-focused groups (RA, PsA, axSpA, SLE, SSc, and OA) identified convergent priorities: earlier detection and interception; validated molecular and clinical endotypes to guide therapy; strategies for immune reset and short-course induction combinations with strict safety oversight; metabolic modifiers; precision targets in axSpA and fibroblast-directed approaches in RA; phenotype-driven therapeutic development and intra-articular options in OA; and pragmatic trial designs that include pregnant persons and very early disease. Across immune-mediated diseases, progress will hinge on validated endotypes, practical interception strategies, and trials that reflect real-world populations. The immediate agenda is to de-risk immune reset and induction approaches, standardise tissue and digital biomarkers, and close evidence gaps for refractory disease. Prevention-and ultimately cure-remains the horizon.