搜索结果：American journal of medical genetics. Part A

This paper introduces a novel track-length extension fitting algorithm for measuring the kinetic energies of inelastically interacting particles in liquid argon time projection chambers (LArTPCs). The algorithm finds the most probable offset in track length for a track-like object by comparing the measured ionization density as a function of position with a theoretical prediction of the energy loss as a function of the energy, including models of electron recombination and detector response. The algorithm can be used to measure the energies of particles that interact before they stop, such as charged pions that are absorbed by argon nuclei. The algorithm's energy measurement resolutions and fractional biases are presented as functions of particle kinetic energy and number of track hits using samples of stopping secondary charged pions in data collected by the ProtoDUNE-SP detector, and also in a detailed simulation. Additional studies describe the impact of the dE/dx model on energy measurement performance. The method described in this paper to characterize the energy measurement performance can be repeated in any LArTPC experiment using stopping secondary charged pions.

This is the third paper of the set recording the results of the suite of tests of general relativity (GR) performed on the signals from the fourth Gravitational-Wave Transient Catalog (GWTC-4.0), where we focus on the remnants of the binary mergers. We examine for the first time 42 events from the first part of the fourth observing run of the LIGO-Virgo-KAGRA detectors, alongside events from the previous observation runs, restricting our analysis to the confident signals, which were measured in at least two detectors and that have false alarm rates $\le 10^{-3} \mathrm{yr}^{-1}$. This paper focuses on seven tests of the coalescence remnants. Three of these are tests of the ringdown and its consistency with the expected quasinormal mode spectrum of a Kerr black hole. Specifically, two tests analyze just the ringdown in the time domain, and the third test analyzes the entire signal in the frequency domain. Four tests allow for the existence of possible echoes arriving after the end of the ringdown, which are not expected in GR. We find overall consistency of the remnants with GR. When combining events by multiplying likelihoods (hierarchically), one analysis finds that the GR predict

The worldwide LIGO-Virgo-KAGRA network of gravitational-wave (GW) detectors continues to increase in sensitivity, thus increasing the quantity and quality of the detected GW signals from compact binary coalescences. These signals allow us to perform ever-more sensitive tests of general relativity (GR) in the dynamical and strong-field regime of gravity. This paper is the first of three, where we present the results of a suite of tests of GR using the binary signals included in the fourth GW Transient Catalog (GWTC-4.0), i.e., up to and including the first part of the fourth observing run of the detectors (O4a). We restrict our analysis to the 91 confident signals, henceforth called events, that were measured by at least two detectors, and have false alarm rates $\le 10^{-3} \mathrm{yr}^{-1}$. These include 42 events from O4a. This first paper presents an overview of the methods, selection of events and GR tests, and serves as a guidemap for all three papers. Here we focus on the four general tests of consistency, where we find no evidence for deviations from our models. Specifically, for all the events considered, we find consistency of the residuals with noise. The final mass and

Rotating non-axisymmetric neutron stars (NSs) are promising sources for continuous gravitational waves (CWs). Such CWs can, if detected, inform us about the internal structure and equation of state of NSs. Here, we present a narrowband search for CWs from known pulsars, for which an efficient and sensitive matched-filter search can be applied. Narrowband searches are designed to be robust to mismatches between the electromagnetic (EM) and gravitational emissions, in contrast to fully targeted searches where the CW emission is assumed to be phase-locked to the EM one. In this work, we search for the CW counterparts emitted by 34 pulsars using data from the first and second parts of the fourth LIGO--Virgo--KAGRA observing run. This is the largest number of pulsars so far targeted for narrowband searches in the advanced detector era. We use the 5n-vector narrowband pipeline, which applies frequency-domain matched filtering. In previous searches, it covered a narrow range in the frequency -- frequency time derivative ($f$ -- $\dot{f}$) space. Here, we also explore a range in the second time derivative of the frequency $\ddot{f}$ around the value indicated by EM observations. Additional

In this second of three papers on tests of general relativity (GR) applied to the compact binary coalescence signals in the fourth Gravitational-Wave Transient Catalog (GWTC-4.0), we present the results of the parameterized tests of GR and constraints on line-of-sight acceleration. We include events up to and including the first part of the fourth observing run (O4a) of the LIGO Virgo KAGRA detectors. As in the other two papers in this series, we restrict our analysis to the 42 confident signals, measured by at least two detectors, that have false alarm rates $\le 10^{-3} \mathrm{yr}^{-1}$ from O4a, in addition to the 49 such events from previous observing runs. This paper focuses on the eight tests that constrain parameterized deviations from the expected GR (or unaccelerated) values. These include modifications of post-Newtonian (PN) parameters, spin-induced quadrupole moments different from those of a binary black hole, and possible dispersive or birefringent propagation effects. Overall, we find no evidence for physics beyond GR, for spin-induced quadrupole moments different from those of a Kerr black hole in GR, or for line of sight acceleration, with more than 90% of the even

We present the results of a blind all-sky search for continuous gravitational-wave signals from neutron stars in binary systems using data from the first part of the fourth observing run (O4a) using LIGO detectors data. Rapidly rotating, non-axisymmetric neutron stars are expected to emit continuous gravitational waves, whose detection would significantly improve our understanding of the galactic neutron star population and matter under extreme conditions, while also providing valuable tests of general relativity. Neutron stars in binary systems likely constitute a substantial fraction of the unobserved galactic population and, due to potential mass accretion, may emit stronger gravitational-wave signals than their isolated counterparts. This search targets signals from neutron stars with frequencies in the 100-350 Hz range, with orbital periods between 7 and 15 days and projected semi-major axes between 5 and 15 light-seconds. The analysis employs the GPU-accelerated fasttracks pipeline. No credible astrophysical signals were identified, and, in the absence of a detection, we report search sensitivity estimates on the population of neutron stars in binary systems in the Milky Way.

We present an all-sky search for long-duration gravitational waves (GWs) from the first part of the LIGO-Virgo-KAGRA fourth observing run (O4), called O4a and comprising data taken between 24 May 2023 and 16 January 2024. The GW signals targeted by this search are the so-called "long-duration" (> 1 s) transients expected from a variety of astrophysical processes, including non-axisymmetric deformations in magnetars or eccentric binary coalescences. We make minimal assumptions on the emitted GW waveforms in terms of morphologies and durations. Overall, our search targets signals with durations ~1-1000 s and frequency content in the range 16-2048 Hz. In the absence of significant detections, we report the sensitivity limits of our search in terms of root-sum-square signal amplitude (hrss) of reference waveforms. These limits improve upon the results from the third LIGO-Virgo-KAGRA observing run (O3) by about 30% on average. Moreover, this analysis demonstrates substantial progress in our ability to search for long-duration GW signals owing to enhancements in pipeline detection efficiencies. As detector sensitivities continue to advance and observational runs grow longer, unmodeled

We present a search for gravitational waves from inspiraling, planetary-mass ultra-compact binaries using data from the first part of the fourth observing run of LIGO, Virgo and KAGRA. Finding no evidence of such systems, we determine the maximum distance reach for such objects and their merger rate densities, independently of how they could have formed. Then, we identify classes of primordial black-hole mass distributions for which these rate limits can be translated into relevant constraints on the mass distribution of primordial black holes, assuming that they compose all of dark matter, in the mass range $[10^{-6},10^{-3}]M_\odot$. Our constraints are consistent with existing microlensing results in the planetary-mass range, and provide a complementary probe to sub-solar mass objects.

We present results from directed searches for continuous gravitational waves from a sample of 15 nearby supernova remnants, likely hosting young neutron star candidates, using data from the first eight months of the fourth observing run (O4) of the LIGO-Virgo-KAGRA Collaboration. The analysis employs five pipelines: four semi-coherent methods -- the Band-Sampled-Data directed pipeline, Weave and two Viterbi pipelines (single- and dual-harmonic) -- and PyStoch, a cross-correlation-based pipeline. These searches cover wide frequency bands and do not assume prior knowledge of the targets' ephemerides. No evidence of a signal is found from any of the 15 sources. We set 95\% confidence-level upper limits on the intrinsic strain amplitude, with the most stringent constraints reaching $\sim 4 \times 10^{-26}$ near 300 Hz for the nearby source G266.2$-$1.2 (Vela Jr.). We also derive limits on neutron star ellipticity and $r$-mode amplitudes for the same source, with the best constraints reaching $\lesssim 10^{-7}$ and $\lesssim 10^{-5}$, respectively, at frequencies above 400 Hz. These results represent the most sensitive wide-band directed searches for continuous gravitational waves from

The discovery of joint sources of high-energy neutrinos and gravitational waves has been a primary target for the LIGO, Virgo, KAGRA, and IceCube observatories. The joint detection of high-energy neutrinos and gravitational waves would provide insight into cosmic processes, from the dynamics of compact object mergers and stellar collapses to the mechanisms driving relativistic outflows. The joint detection of multiple cosmic messengers can also elevate the significance of the common observation even when some or all of the constituent messengers are sub-threshold, i.e. not significant enough to declare their detection individually. Using data from the LIGO, Virgo, and IceCube observatories, including sub-threshold events, we searched for common sources of gravitational waves and high-energy neutrinos during the third observing run of Advanced LIGO and Advanced Virgo detectors. Our search did not identify significant joint sources. We derive constraints on the rate densities of joint sources. Our results constrain the isotropic neutrino emission from gravitational-wave sources for very high values of the total energy emitted in neutrinos (> $10^{52} - 10^{54}$ erg).

Version 4.0 of the Gravitational-Wave Transient Catalog (GWTC-4.0) adds new candidates detected by the LIGO, Virgo, and KAGRA observatories through the first part of the fourth observing run (O4a: 2023 May 24 15:00:00 to 2024 January 16 16:00:00 UTC) and a preceding engineering run. In this new data, we find 128 new compact binary coalescence candidates that are identified by at least one of our search algorithms with a probability of astrophysical origin $p_{\rm astro} \geq 0.5$ and that are not vetoed during event validation. We also provide detailed source property measurements for 86 of these that have a false alarm rate $< 1 \rm{yr}^{-1}$. Based on the inferred component masses, these new candidates are consistent with signals from binary black holes and neutron star-black hole binaries (GW230518_125908 and GW230529_181500). Median inferred component masses of binary black holes in the catalog now range from $5.79\,M_\odot$ (GW230627_015337) to $137\,M_\odot$ (GW231123_135430), while GW231123_135430 was probably produced by the most massive binary observed in the catalog. For the first time we have discovered binary black hole signals with network signal-to-noise ratio exce

The Gravitational-Wave Transient Catalog (GWTC) is a collection of short-duration (transient) gravitational wave signals identified by the LIGO-Virgo-KAGRA Collaboration in gravitational-wave data produced by the eponymous detectors. The catalog provides information about the identified candidates, such as the arrival time and amplitude of the signal and properties of the signal's source as inferred from the observational data. GWTC is the data release of this dataset and version 4.0 extends the catalog to include observations made during the first part of the fourth LIGO-Virgo-KAGRA observing run up until 2024 January 31. This paper marks an introduction to a collection of articles related to this version of the catalog, GWTC-4.0. The collection of articles accompanying the catalog provides documentation of the methods used to analyze the data, summaries of the catalog of events, observational measurements drawn from the population, and detailed discussions of selected candidates

Continuous gravitational waves (CWs) emission from neutron stars carries information about their internal structure and equation of state, and it can provide tests of General Relativity. We present a search for CWs from a set of 45 known pulsars in the first part of the fourth LIGO--Virgo--KAGRA observing run, known as O4a. We conducted a targeted search for each pulsar using three independent analysis methods considering the single-harmonic and the dual-harmonic emission models. We find no evidence of a CW signal in O4a data for both models and set upper limits on the signal amplitude and on the ellipticity, which quantifies the asymmetry in the neutron star mass distribution. For the single-harmonic emission model, 29 targets have the upper limit on the amplitude below the theoretical spin-down limit. The lowest upper limit on the amplitude is $6.4\!\times\!10^{-27}$ for the young energetic pulsar J0537-6910, while the lowest constraint on the ellipticity is $8.8\!\times\!10^{-9}$ for the bright nearby millisecond pulsar J0437-4715. Additionally, for a subset of 16 targets we performed a narrowband search that is more robust regarding the emission model, with no evidence of a sig

We present results from an all-sky search for continuous gravitational waves, using three different methods applied to the first eight months of LIGO data from the fourth LIGO-Virgo-KAGRA Collaboration s observing run. We aim at signals potentially emitted by rotating, non-axisymmetric isolated neutron star in the Milky Way. The analysis spans a frequency range from 20 Hz to 2000 Hz and accommodates frequency derivative magnitudes up to $10^{-8}$ Hz/s. No statistically significant periodic gravitational wave signals were detected. We establish 95% confidence-level (CL) frequentist upper limits on the dimensionless strain amplitudes. The most stringent population-averaged strain upper limits reach 9.7 $\times$ $10^{-26}$ near 290 Hz, matching the best previous constraints from 250 to $\sim$1700 Hz while extending coverage to a much broader spin-down range. At higher frequencies, the new limits improve upon previous results by factors of approximately $\sim$1.6. These constraints are applied to three astrophysical scenarios: 1) the distribution of galactic neutron stars as a function of spin frequency and ellipticity; 2) the contribution of millisecond pulsars to the GeV excess near

The angular distribution of gravitational-wave power from persistent sources may exhibit anisotropies arising from the large-scale structure of the Universe. This motivates directional searches for astrophysical and cosmological gravitational-wave backgrounds, as well as continuous-wave emitters. We present results of such a search using data from the first observing run through the first portion of the fourth observing run of the LIGO-Virgo-KAGRA Collaborations. We apply gravitational-wave radiometer techniques to generate skymaps and search for both narrowband and broadband persistent gravitational-wave sources. Additionally, we use spherical harmonic decomposition to probe spatially extended sources. No evidence of persistent gravitational-wave signals is found, and we set the most stringent constraints to date on such emissions. For narrowband point sources, our sensitivity estimate to effective strain amplitude lies in the range $(0.03 - 8.4) \times 10^{-24}$ across all sky and frequency range $(20 - 160)$ Hz. For targeted sources -- Scorpius X-1, SN 1987A, the Galactic Center, Terzan 5, and NGC 6397 -- we constrain the strain amplitude with best limits ranging from $\sim 1.1

LIGO, Virgo, and KAGRA form a network of gravitational-wave observatories. Data and analysis results from this network are made publicly available through the Gravitational Wave Open Science Center. This paper describes open data from this network, including the addition of data from the first part of the fourth observing run (O4a) and selected periods from the preceding engineering run, collected from May 2023 to January 2024. The public data set includes calibrated strain time series for each instrument, data from additional channels used for noise subtraction and detector characterization, and analysis data products from version 4.0 of the Gravitational-Wave Transient Catalog.

We present the first directed searches for long-transient and continuous gravitational waves from ultralight vector boson clouds around known black holes (BHs). We use LIGO data from the first part of the fourth LIGO-Virgo-KAGRA observing run. The searches target two distinct types of BHs and use two new semicoherent methods: hidden Markov model (HMM) tracking for the remnant BHs of the mergers GW230814_230901 and GW231123_135430 (referred to as GW230814 and GW231123 in this study), and a dedicated method using the Band Sampled Data (BSD) framework for the galactic BH in the Cygnus X-1 binary system. Without finding evidence of a signal from vector bosons in the data, we estimate the mass range that can be constrained. For the HMM searches targeting the remnants from GW231123 and GW230814, we disfavor vector boson masses in the ranges $[0.94, 1.08]$ and $[2.75, 3.28] \times 10^{-13}$ eV, respectively, at 30% confidence, assuming a 1% false alarm probability. Although these searches are only marginally sensitive to signals from merger remnants at relatively large distances, future observations are expected to yield more stringent constraints with high confidence. For the BSD search

We present results from the search for an isotropic gravitational-wave background using Advanced LIGO and Advanced Virgo data from O1 through O4a, the first part of the fourth observing run. This background is the accumulated signal from unresolved sources throughout cosmic history and encodes information about the merger history of compact binaries throughout the Universe, as well as exotic physics and potentially primordial processes from the early cosmos. Our cross-correlation analysis reveals no statistically significant background signal, enabling us to constrain several theoretical scenarios. For compact binary coalescences which approximately follow a 2/3 power-law spectrum, we constrain the fractional energy density to $Ω_{\rm GW}(25{\rm Hz})\leq 2.0\times 10^{-9}$ (95% cred.), a factor of 1.7 improvement over previous results. Scale-invariant backgrounds are constrained to $Ω_{\rm GW}(25{\rm Hz})\leq 2.8\times 10^{-9}$, representing a 2.1x sensitivity gain. We also place new limits on gravity theories predicting non-standard polarization modes and confirm that terrestrial magnetic noise sources remain below detection threshold. Combining these spectral limits with populati

Volume 1 of the FCC Feasibility Report presents an overview of the physics case, experimental programme, and detector concepts for the Future Circular Collider (FCC). This volume outlines how FCC would address some of the most profound open questions in particle physics, from precision studies of the Higgs and EW bosons and of the top quark, to the exploration of physics beyond the Standard Model. The report reviews the experimental opportunities offered by the staged implementation of FCC, beginning with an electron-positron collider (FCC-ee), operating at several centre-of-mass energies, followed by a hadron collider (FCC-hh). Benchmark examples are given of the expected physics performance, in terms of precision and sensitivity to new phenomena, of each collider stage. Detector requirements and conceptual designs for FCC-ee experiments are discussed, as are the specific demands that the physics programme imposes on the accelerator in the domains of the calibration of the collision energy, and the interface region between the accelerator and the detector. The report also highlights advances in detector, software and computing technologies, as well as the theoretical tools /recons