Human grasps can be roughly categorized into two types: power grasps and precision grasps. Precision grasping enables tool use and is believed to have influenced human evolution. Today's multi-fingered robotic hands are effective in power grasps, but for tasks requiring precision, parallel grippers are still more widely adopted. This contrast highlights a key limitation in current robotic hand design: the difficulty of achieving both stable power grasps and precise, fine-grained manipulation within a single, versatile system. In this work, we bridge this gap by jointly optimizing the control and hardware design of a multi-fingered dexterous hand, enabling both power and precision manipulation. Rather than redesigning the entire hand, we introduce a lightweight fingertip geometry modification, represent it as a contact plane, and jointly optimize its parameters along with the corresponding control. Our control strategy dynamically switches between power and precision manipulation and simplifies precision control into parallel thumb-index motions, which proves robust for sim-to-real transfer. On the design side, we leverage large-scale simulation to optimize the fingertip geometry us
Thermal expansion is a significant source of positioning error in high-precision hexapod robots (Gough-Stewart platforms). Any variation in the temperature of the hexapod's parts induces expansion, which alters their kinematic model and reduces the robot's accuracy and repeatability. These variations may arise from internal heat sources (such as motors, encoders, and electronics) or from environmental changes. In this study, a method is proposed to anticipate and therefore correct the thermal drift of one of the hexapod precision electro-mechanical actuators. This method is based on determining a model that links the expansion state of the actuator at any given moment to the temperature of some well-chosen points on its surface. This model was initially developed theoretically. Its coefficients were then adjusted experimentally on a specific test-bench, based on a rigorous measurement campaign of actuator expansion using a high-precision interferometric measurement system. Experimental validation demonstrates a reduction of thermally induced expansion by more than 80%. This paves the way for thermal drift correction across the entire robot or similar robotics parts.
Reference-free faithfulness metrics verify each atomic claim a model makes against ground truth, and are increasingly used to evaluate grounded generation. We show they share a blind spot: they measure only precision -- are the stated claims supported? -- and therefore reward abstention, since a model can score near-perfect faithfulness by saying almost nothing. We make this measurable using Formula 1 telemetry, a domain where strategic ground truth is derived deterministically and, crucially, completely: for each decision we know the full set of facts that mattered. This completeness -- absent in open-domain faithfulness benchmarks -- lets us measure recall (coverage of the relevant facts) exactly, alongside precision. On a multilingual (EN/ES/PT) benchmark of 7,253 decision instances spanning 157 races, the most precise frontier model covers under half of the relevant facts and ranks last by F1, so requiring coverage reorders the systems; the same effect reappears in a second complete-oracle domain (NOAA weather forecasts). Fine-tuning small models (1B-7B) on the complete oracle closes the precision-recall gap entirely (F1 ~0.98), beating every zero-shot frontier system regardles
In this paper we develop the first fine-grained rounding error analysis of finite element (FE) cell kernels and assembly. The theory includes mixed-precision implementations and accounts for hardware-acceleration via matrix multiplication units, thus providing theoretical guidance for designing reduced- and mixed-precision FE algorithms on CPUs and GPUs. Guided by this analysis, we introduce hardware-accelerated mixed-precision implementation strategies which are provably robust to low-precision computations. Indeed, these algorithms are accurate to the lower-precision unit roundoff with an error constant that is independent from: the conditioning of FE basis function evaluations, the ill-posedness of the cell, the polynomial degree, and the number of quadrature nodes. Consequently, we present the first AMX-accelerated FE kernel implementations on Intel Sapphire Rapids CPUs. Numerical experiments demonstrate that the proposed mixed- (single/half-) precision algorithms are up to 60 times faster than their double precision equivalent while being orders of magnitude more accurate than their fully half-precision counterparts.
FP8 (E4M3) acceleration for attention computation offers significant throughput gains, but the 3-bit mantissa introduces precision challenges when the softmax probability matrix~$P$ is cast to FP8 before the $P \cdot V$ matrix multiplication. We analyze two implementation choices that affect output precision under the \emph{Attention Sink} phenomenon: (1)~the KV block iteration order, and (2) the static scaling factor applied to $P$ before casting. We show that forward KV iteration causes \emph{P-collapse} -- to leading order a fraction $Φ(Δ+ δ_k - 6.93 - \ln S)$ of non-sink $P$ values underflow to zero, where the small shift $δ_k \approx 1$ (for $k_{\text{sink}}{=}4$) is the expected within-sink-block score maximum -- and that reverse iteration removes it, with a zero-underflow guarantee when reverse is combined with $S{=}256$. We further give a constructive characterization of $S = 256 = 2^8$ as the static scale that simultaneously satisfies (i)~bit-exact IEEE 754 scaling, (ii) the lower envelope of a sawtooth function $dp(S)$ over the E4M3 number line ($dp = 2^{-4}$, the minimum worst-case quantization step), and (iii)~the maximum normal-range coverage \emph{among bit-exact ($2^
This document summarizes the discussions at the program "Precision QCD with the Electron Ion Collider", held from May to June 2025 at the Institute for Nuclear Theory (INT) at the University of Washington. The program was co-sponsored by the INT and by the Center for Frontiers in Nuclear Science (CFNS, Stony Brook University). Over its five-week duration it brought together about 70 theorists, experimentalists and computer scientists all interested in the physics program at the future Electron Ion Collider in preparation at Brookhaven National Laboratory. Key topics at the program were: higher-order perturbative-QCD calculations and techniques; nuclear structure and tomography; comparisons of phenomenological and lattice determinations of parton distribution functions; identification of signature observables for saturated gluons; assessment of the importance of AI techniques for EIC studies and detector development.
Recently, considerable efforts have been directed towards compressing Large Language Models (LLMs), which showcase groundbreaking capabilities across diverse applications but entail significant deployment costs due to their large sizes. Meanwhile, much less attention has been given to mitigating the costs associated with deploying multiple LLMs of varying sizes despite its practical significance. Thus, this paper introduces \emph{any-precision LLM}, extending the concept of any-precision DNN to LLMs. Addressing challenges in any-precision LLM, we propose a lightweight method for any-precision quantization of LLMs, leveraging a post-training quantization framework, and develop a specialized software engine for its efficient serving. As a result, our solution significantly reduces the high costs of deploying multiple, different-sized LLMs by overlaying LLMs quantized to varying bit-widths, such as 3, 4, ..., $n$ bits, into a memory footprint comparable to a single $n$-bit LLM. All the supported LLMs with varying bit-widths demonstrate state-of-the-art model quality and inference throughput, proving itself to be a compelling option for deployment of multiple, different-sized LLMs. Our
Atomic precision advanced manufacturing (APAM) dopes silicon with enough carriers to change its electronic structure and can be used to create novel devices by defining metallic regions whose boundaries have single-atom abruptness. Incompatibility with the thermal and lithography process requirements for gated silicon transistor manufacturing have inhibited exploration of both how APAM can enhance CMOS performance and how transistor manufacturing steps can accelerate the discovery of new APAM device concepts. In this work, we introduce an APAM process that enables direct integration into the middle of a transistor manufacturing workflow. We show that a process that combines sputtering and annealing with a hardmask preserves a defining characteristic of APAM, a doping density far in excess of the solid solubility limit, while trading another, the atomic precision, for compatibility with manufacturing. The electrical characteristics of a chip combining a transistor with an APAM resistor show that the APAM module has only affected the transistor through the addition of a resistance and not by altering the transistor. This proof-of-concept demonstration also outlines the requirements a
Event cameras are a new type of brain-inspired visual sensor with advantages such as high dynamic range and high temporal resolution. The geometric calibration of event cameras, which involves determining their intrinsic and extrinsic parameters, particularly in long-range measurement scenarios, remains a significant challenge. To address the dual requirements of long-distance and high-precision measurement, we propose an event camera calibration method utilizing a collimator with flickering star-based patterns. The proposed method first linearly solves camera parameters using the sphere motion model of the collimator, followed by nonlinear optimization to refine these parameters with high precision. Through comprehensive real-world experiments across varying conditions, we demonstrate that the proposed method consistently outperforms existing event camera calibration methods in terms of accuracy and reliability.
Common remote sensing modalities (RGB, multispectral, hyperspectral imaging or LiDAR) are often used to indirectly measure crop health and do not directly capture plant stress indicators. Commercially available direct leaf sensors are bulky, powered electronics that are expensive and interfere with crop growth. In contrast, low-cost, passive and bio-degradable leaf sensors offer an opportunity to advance real-time monitoring as they directly interface with the crop surface while not interfering with crop growth. To this end, we co-design a sensor-detector system, where the sensor is a passive colorimetric leaf sensor that directly measures crop health in a precision agriculture setting, and the detector autonomously obtains optical signals from these leaf sensors. The detector comprises a low size weight and power (SWaP) mobile ground robot with an onboard monocular RGB camera and object detector to localize each leaf sensor, as well as a hyperspectral camera with a motorized mirror and halogen light to acquire hyperspectral images. The sensor's crop health-dependent optical signals can be extracted from the hyperspectral images. The proof-of-concept system is demonstrated in row-c
Precision health, increasingly supported by digital technologies, is a domain of research that broadens the paradigm of precision medicine, advancing everyday healthcare. This vision goes hand in hand with the groundbreaking advent of artificial intelligence (AI), which is reshaping the way we diagnose, treat, and monitor both clinical subjects and the general population. AI tools powered by machine learning have shown considerable improvements in a variety of healthcare domains. In particular, reinforcement learning (RL) holds great promise for sequential and dynamic problems such as dynamic treatment regimes and just-in-time adaptive interventions in digital health. In this work, we discuss the opportunity offered by AI, more specifically RL, to current trends in healthcare, providing a methodological survey of RL methods in the context of precision and digital health. Focusing on the area of adaptive interventions, we expand the methodological survey with illustrative case studies that used RL in real practice. This invited article has undergone anonymous review and is intended as a book chapter for the volume "Frontiers of Statistics and Data Science" edited by Subhashis Ghosha
We review the current status and techniques used in precision measurements of the effective leptonic weak mixing angle $\sin^2θ^\ell_{\rm eff}$ (a fundamental parameter of the Standard Model (SM)) in the region of the Z pole with emphasis on hadron colliders. We also build on these techniques to extract the most precise single measurement to date of $\sin^2θ^\ell_{\rm eff}$ from a new analysis of the published forward-backward asymmetry ($A_{\rm FB}$) in Drell-Yan dielpton production in proton-proton collisions at a center of mass energy of 13 TeV measured by the CMS collaboration at the large hadron collider. The uncertainty in $\sin^2θ^\ell_{\rm eff}$ published by CMS is dominated by uncertainties in Parton Distribution Functions (PDFs), which are reduced by PDF profiling using the dilepton mass dependence of $A_{\rm FB}$. Our new extraction of $\sin^2θ^\ell_{\rm eff}$ from the CMS values of $A_{\rm FB}$ includes profiling with additional new CMS measurements of the $W$-boson decay lepton asymmetry, and W/Z cross section ratio at 13 TeV. We obtain the most precise single measurement of $\sin^2θ^\ell_{\rm eff}$ to date of 0.23156$\pm$0.00024, which is in excellent agreement with t
Precision rehabilitation offers the promise of an evidence-based approach for optimizing individual rehabilitation to improve long-term functional outcomes. Emerging techniques, including those driven by artificial intelligence, are rapidly expanding our ability to quantify the different domains of function during rehabilitation, other encounters with healthcare, and in the community. While this seems poised to usher rehabilitation into the era of big data and should be a powerful driver of precision rehabilitation, our field lacks a coherent framework to utilize these data and deliver on this promise. We propose a framework that builds upon multiple existing pillars to fill this gap. Our framework aims to identify the Optimal Dynamic Treatment Regimens (ODTR), or the decision-making strategy that takes in the range of available measurements and biomarkers to identify interventions likely to maximize long-term function. This is achieved by designing and fitting causal models, which extend the Computational Neurorehabilitation framework using tools from causal inference. These causal models can learn from heterogeneous data from different silos, which must include detailed documenta
The unprecedented precision of experimental measurements at the Large Hadron Collider (LHC) and the increased statistics that will be reached in the High-Luminosity phase of the LHC (HL-LHC) are pushing the phenomenology community to a new precision frontier, in which new challenges present themselves and new questions arise. A key ingredients of theoretical predictions at hadron colliders are the Parton Distribution Functions (PDFs) of the proton. This contribution highlights some of the new developments in the determination of PDFs from a global set of experimental data, from approximate N3LO PDFs and the inclusion of theory uncertainties in PDF fits, to the realisation of the non trivial interplay between parton densities at large-x and possible signals of New Physics in high energy tails of the distributions, which highlights the synergy between high energy and low energy experimental programs.
Epileptic seizures arise from abnormally synchronised neural activity and remain a major global health challenge, affecting more than 50 million people worldwide. Despite advances in pharmacological interventions, a significant proportion of patients continue to experience uncontrolled seizures, underscoring the need for alternative neuromodulation strategies. Rhythmic neural entrainment has recently emerged as a promising mechanism for disrupting pathological synchrony, but most existing systems rely on complex analogue electronics or high-power stimulation hardware. This study investigates a minimal digital custom-designed chip that generates a stable 6 Hz oscillation capable of entraining epileptic seizure activity. Using a publicly available EEG seizure dataset, we extracted and averaged analogue seizure waveforms, digitised them to emulate neural front-ends, and directly interfaced the digitised signals with digital output recordings acquired from the chip using a Saleae Logic analyser. The chip pulse train was resampled and low-pass-reconstructed to produce an analogue 6 Hz waveform, allowing direct comparison between seizure morphology, its digitised representation, and the
We present the history and current status of the YFS Monte Carlo approach to precision theory for accelerator physics experiments. Key contributions of Prof. Stanislaw Jadach are highlighted
The last few years have seen rapid progress in transitioning quantum computing from lab to industry. In healthcare and life sciences, more than 40 proof-of-concept experiments and studies have been conducted; an increasing number of these are even run on real quantum hardware. Major investments have been made with hundreds of millions of dollars already allocated towards quantum applications and hardware in medicine. In addition to pharmaceutical and life sciences uses, clinical and medical applications are now increasingly coming into the picture. This chapter focuses on three key use case areas associated with (precision) medicine, including genomics and clinical research, diagnostics, and treatments and interventions. Examples of organizations and the use cases they have been researching are given; ideas how the development of practical quantum computing applications can be further accelerated are described.
We present high-precision radial velocity (RV) observations of Gaia BH1, the nearest known black hole (BH). The system contains a solar-type G star orbiting a massive dark companion, which could be either a single BH or an inner BH + BH binary. A BH + BH binary is expected in some models where Gaia BH1 formed as a hierarchical triple, which are attractive because they avoid many of the difficulties associated with forming the system through isolated binary evolution. Our observations test the inner binary scenario. We have measured 115 precise RVs of the G star, including 40 from ESPRESSO with a precision of $3$-$5$ m s$^{-1}$, and 75 from other instruments with a typical precision of $30$-$100$ m s$^{-1}$. Our observations span $2.33$ orbits of the G star and are concentrated near a periastron passage, when perturbations due to an inner binary would be largest. The RVs are well-fit by a Keplerian two-body orbit and show no convincing evidence of an inner binary. Using REBOUND simulations of hierarchical triples with a range of inner periods, mass ratios, eccentricities, and orientations, we show that plausible inner binaries with periods $P_{\text{inner}} \gtrsim 1.5$ days would h
The success of precision medicine requires computational models that can effectively process and interpret diverse physiological signals across heterogeneous patient populations. While foundation models have demonstrated remarkable transfer capabilities across various domains, their effectiveness in handling individual-specific physiological signals - crucial for precision medicine - remains largely unexplored. This work introduces a systematic pipeline for rapidly and efficiently evaluating foundation models' transfer capabilities in medical contexts. Our pipeline employs a three-stage approach. First, it leverages physiological simulation software to generate diverse, clinically relevant scenarios, particularly focusing on data-scarce medical conditions. This simulation-based approach enables both targeted capability assessment and subsequent model fine-tuning. Second, the pipeline projects these simulated signals through the foundation model to obtain embeddings, which are then evaluated using linear methods. This evaluation quantifies the model's ability to capture three critical aspects: physiological feature independence, temporal dynamics preservation, and medical scenario d
Stellar chemical abundances have proved themselves a key source of information for understanding the evolution of the Milky Way, and the scale of major stellar surveys such as GALAH have massively increased the amount of chemical data available. However, progress is hampered by the level of precision in chemical abundance data as well as the visualization methods for comparing the multidimensional outputs of chemical evolution models to stellar abundance data. Machine learning methods have greatly improved the former; while the application of tree-building or phylogenetic methods borrowed from biology are beginning to show promise with the latter. Here we analyse a sample of GALAH solar twins to address these issues. We apply The Cannon algorithm to generate a catalogue of about 40,000 solar twins with 14 high precision abundances which we use to perform a phylogenetic analysis on a selection of stars that have two different ranges of eccentricities. From our analyses we are able to find a group with mostly stars on circular orbits and some old stars with eccentric orbits whose age-[Y/Mg] relation agrees remarkably well with the chemical clocks published by previous high precision