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Image augmentations are quintessential for effective visual representation learning across self-supervised learning techniques. While augmentation strategies for natural imaging have been studied extensively, medical images are vastly different from their natural counterparts. Thus, it is unknown whether common augmentation strategies employed in Siamese representation learning generalize to medical images and to what extent. To address this challenge, in this study, we systematically assess the effect of various augmentations on the quality and robustness of the learned representations. We train and evaluate Siamese Networks for abnormality detection on chest X-Rays across three large datasets (MIMIC-CXR, CheXpert and VinDR-CXR). We investigate the efficacy of the learned representations through experiments involving linear probing, fine-tuning, zero-shot transfer, and data efficiency. Finally, we identify a set of augmentations that yield robust representations that generalize well to both out-of-distribution data and diseases, while outperforming supervised baselines using just zero-shot transfer and linear probes by up to 20%. Our code is available at https://github.com/Stanfor

We incorporate a contribution to reionization from X-rays within analytic and semi-numerical simulations of the 21-cm signal arising from neutral hydrogen during the epoch of reionization. We explore the impact that X-ray ionizations have on the power spectrum (PS) of 21-cm fluctuations by varying both the average X-ray MFP and the fractional contribution of X-rays to reionization. In general, prior to the epoch when the intergalactic medium is dominated by ionized regions (H {\sevensize II} regions), X-ray-induced ionization enhances fluctuations on spatial scales smaller than the X-ray MFP, provided that X-ray heating does not strongly supress galaxy formation. Conversely, at later times when \H2 regions dominate, small-scale fluctuations in the 21-cm signal are suppressed by X-ray ionization. Our modelling also shows that the modification of the 21-cm signal due to the presence of X-rays is sensitive to the relative scales of the X-ray MFP, and the characteristic size of \H2 regions. We therefore find that X-rays imprint an epoch and scale-dependent signature on the 21-cm PS, whose prominence depends on fractional X-ray contribution. The degree of X-ray heating of the IGM also d

A distinct low energy cosmic-ray component has been proposed to explain the essentially constant Be/Fe ratio at low metallicities. Atomic collisions of such low energy ions produce characteristic nonthermal X-ray emission. In this paper, we study the possible contribution of such X-rays to the Galactic ridge emission. We show that they would account for < 10% of the 10-60 keV luminosity of the thin Galactic disk component detected with RXTE. They could make a more significant contribution in the 0.5-10 keV energy range, provided that the nonthermal ion population extends down to about 1 MeV/nucleon and delivers about 10$^{42}$ erg s$^{-1}$ to the interstellar medium, comparable to the total power suplied by the Galactic supernovae. But since the nonthermal X-rays in this energy range are essentially produced below the thresholds of the Be-producing cross sections, their detection does not necessarily imply a low energy cosmic-ray origin for the spallogenic light elements. A significant contribution of nonthermal X-rays could alleviate the problem of the origin of the hard component observed with ASCA in the Scutum arm region.

Thanks to the high sensitivity of the instruments on board the XMM-Newton and Chandra satellites, it has become possible to explore the properties of the X-ray emission from hot subdwarfs. The small but growing sample of hot subdwarfs detected in X-rays includes binary systems, in which the X-rays result from wind accretion onto a compact companion (white dwarf or neutron star), as well as isolated sdO stars in which X-rays are probably due to shock instabilities in the wind. X-ray observations of these low mass stars provide information which can be useful also for our understanding of the winds of more luminous and massive early-type stars and can lead to the discovery of particularly interesting binary systems.

The Spectrometer/Telescope for Imaging X-rays (STIX) is one of the 10 instruments on-board the scientific payload of ESA's Solar Orbiter mission. STIX provides hard X-ray imaging spectroscopy in the 4-150~keV energy range, observing hard X-ray bremsstrahlung emission from the Sun. These observations provide diagnostics of the hottest thermal plasmas ($>$10~MK) and information on the non-thermal energetic electrons accelerated above 10~keV during solar flares. STIX has a spectral resolution of 1~keV, and employs the use of in-direct bi-grid Fourier imaging to spatially locate hard X-ray emission. Given that STIX provides critical information about accelerated electrons at the Sun through hard X-ray diagnostics, it is a powerful contribution to the Solar Orbiter suite and has a significant role to explore the dynamics of solar inputs to the heliosphere. This chapter describes the STIX instrument, its design, objectives, first observations and outlines the new perspectives STIX provides over the mission lifetime of Solar Orbiter.

On January 10 and 13, 2001, Venus was observed for the first time with an X-ray astronomy satellite. The observation, performed with the ACIS-I and LETG/ACIS-S instruments on Chandra, yielded data of high spatial, spectral, and temporal resolution. Venus is clearly detected as a half-lit crescent, with considerable brightening on the sunward limb. The morphology agrees well with that expected from fluorescent scattering of solar X-rays in the planetary atmosphere. The radiation is observed at discrete energies, mainly at the O-K_alpha energy of 0.53 keV. Fluorescence radiation is also detected from C-K_alpha at 0.28 keV and, marginally, from N-K_alpha at 0.40 keV. An additional emission line is indicated at 0.29 keV, which might be the signature of the C 1s --> pi* transition in CO2 and CO. Evidence for temporal variability of the X-ray flux was found at the 2.6 sigma level, with fluctuations by factors of a few times indicated on time scales of minutes. All these findings are fully consistent with fluorescent scattering of solar X-rays. No other source of X-ray emission was detected, in particular none from charge exchange interactions between highly charged heavy solar wind io

The role of X-ray observations for cosmological studies and conclusions is briefly explored. X-rays currently yield cosmologically interesting results on the abundances, evolution and gas content of clusters of galaxies, on the clustering and evolution of active galaxies and on the X-ray Background. They are unlikely in the long term future to give the most precise values of the cosmological parameters, although in the short term the baryon fraction of clusters and the Sunyaev-Zeldovich effect will remain important determinants and checks for some parameters. X-rays will however continue to play an important role in studying the astrophysics of the formation and growth of black holes, galaxies, groups and clusters. It is possible that this role will be crucial, if winds from active galaxies are responsible for breaking the simple gravitational scaling laws for clusters.

Although blazars are thought to emit most of their luminosity in the gamma-ray band, there are subclasses of them very prominent in hard X-rays. These are the best candidates to be studied by Simbol-X. They are at the extremes of the blazar sequence, having very small or very high jet powers. The former are the class of TeV emitting BL Lacs, whose synchrotron emission often peaks at tens of keV or more. The latter are the blazars with the most powerful jets and have high black hole masses accreting at high (i.e. close to Eddington) rates. These sources are predicted to have their high energy peak even below the MeV band, and therefore are very promising candidates to be studied with Simbol-X.

Blazars are known to display strong and erratic variability at almost all the wavelengths of electromagnetic spectrum. Presently, variability studies at high-energies (hard X-rays, gamma-rays) are hampered by low sensitivity of the instruments. Nevertheless, the latest generation of satellites (INTEGRAL, Swift) have given suggestions not yet fully confirmed of variability on intraday timescales. Some specific cases recently observed are presented and physical implications are discussed (e.g. NRAO 530). The contribution that SIMBOL-X could give in this research topic is also outlined.

Ultrafast X-rays revealed how a molecule converts absorbed light into motion in just trillionths of a second。 Individual atoms recorded different stages of the process, opening a powerful new window into light-driven chemistry

Using a Monte Carlo method, we study Compton scattering and absorption of X-rays and gamma-rays in cold media. We consider transmission of X/gamma-rays through a shell of an arbitrary optical depth, for which we derive energy-dependent Green's functions. Fitting the Green functions with simple analytical formulae is in progress. We also present a simple treatment of the effect of absorption on Green's functions for Compton scattering, which allow to treat media with an arbitrary ionization state and chemical composition. Our transmission Green's functions allow to treat Thomson-thick absorbers, e.g. molecular tori of Seyfert 2s.

Using Chandra ACIS-S, we have obtained imaging Xray spectrophotometry of the Pluto system in support of the New Horizons flyby on 14 July 2015. 174 ksec of observations were obtained on 4 visits in Feb 2014 to Aug 2015. We measured a net signal of 6.8 counts and a noise level of 1.2 counts in a comoving 11 x 11 pixel box (100 x 100 R_Pluto) in the 0.31 to 0.60 keV passband for a detection at > 99.95 C.L. The Pluto photons do not match the background spectrum, are coincident with a 90% flux aperture comoving with Pluto, and are not sky source confused. The mean 0.31 to 0.60 keV Xray power from Pluto is 200 MW, in the midrange of Xray power levels seen for known solar system emission sources: auroral precipitation, solar Xray scattering, and charge exchange (CXE) between solar wind (SW) ions & atmospheric neutrals. We eliminate auroral effects as a source, as Pluto has no known magnetic field & the New Horizons Alice UV spectrometer detected no airglow from Pluto during the flyby. Nano-scale atmospheric haze particles could lead to enhanced resonant scattering of solar X-rays from Pluto, but the energy signature of the detected photons does not match the solar spectrum and

A subset (~ 10%) of massive stars present strong, globally ordered (mostly dipolar) magnetic fields. The trapping and channeling of their stellar winds in closed magnetic loops leads to magnetically confined wind shocks (MCWS), with pre-shock flow speeds that are some fraction of the wind terminal speed. These shocks generate hot plasma, a source of X-rays. In the last decade, several developments took place, notably the determination of the hot plasma properties for a large sample of objects using XMM-Newton and Chandra, as well as fully self-consistent MHD modelling and the identification of shock retreat effects in weak winds. Despite a few exceptions, the combination of magnetic confinement, shock retreat and rotation effects seems to be able to account for X-ray emission in massive OB stars. Here we review these new observational and theoretical aspects of this X-ray emission and envisage some perspectives for the next generation of X-ray observatories.

The INTEGRAL archive developed at INAF-IASF Milano with the available public observations from late 2002 to 2016 is investigated to extract the X-ray properties of 58 High Mass X-ray Binaries (HMXBs). This sample consists of sources hosting either a Be star (Be/XRBs) or an early-type supergiant companion (SgHMXBs), including the Supergiant Fast X-ray Transients (SFXTs). INTEGRAL light curves (sampled at 2 ks) are used to build their hard X-ray luminosity distributions, returning the source duty cycles, the range of variability of the X-ray luminosity and the time spent in each luminosity state. The phenomenology observed with INTEGRAL, together with the source variability at soft X-rays taken from the literature, allows us to obtain a quantitative overview of the main sub-classes of massive binaries in accretion (Be/XRBs, SgHMXBs and SFXTs). Although some criteria can be derived to distinguish them, some SgHMXBs exist with intermediate properties, bridging together persistent SgHMXBs and SFXTs.

X-ray studies of high-redshift (z > 4) active galaxies have advanced substantially over the past few years, largely due to results from the new generation of X-ray observatories. As of this writing X-ray emission has been detected from nearly 60 high-redshift active galaxies. This paper reviews the observational results and their implications for models of the first massive black holes, and it discusses future prospects for the field.