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No AccessJournal of UrologyAdult Urology1 Oct 2009Guideline for Management of the Clinical T1 Renal Massis accompanied byIncreased Tissue Factor Expression and Poor Nephroblastoma PrognosisPercutaneous Microwave Ablation or Nephrectomy for VX-2 Carcinoma in Rabbit KidneyTemporary Segmental Renal Artery Occlusion Using Reverse Phase Polymer for Bloodless Robotic Partial Nephrectomy Steven C. Campbell, Andrew C. Novick, Arie Belldegrun, Michael L. Blute, George K. Chow, Ithaar H. Derweesh, Martha M. Faraday, Jihad H. Kaouk, Raymond J. Leveillee, Surena F. Matin, Paul Russo, and Robert G. Uzzo Steven C. CampbellSteven C. Campbell Financial interest and/or other relationship with Pfizer, Sanofi Aventis, Novartis, Aventis Pharmaceuticals. More articles by this author , Andrew C. NovickAndrew C. Novick The Panel dedicates this work to Dr. Andrew Novick, who served as Chair of the Panel until his untimely death in 2008. Dr. Novick was well recognized for his contributions to renal surgery, and kidney cancer in particular. More articles by this author , Arie BelldegrunArie Belldegrun Financial interest and/or other relationship with Galil Medical, Wilex, Bayer, Pfizer, ROEI Medical, Amgen, Agensys, Hana Biosciences, Cougar Biotechnology. More articles by this author , Michael L. BluteMichael L. Blute More articles by this author , George K. ChowGeorge K. Chow More articles by this author , Ithaar H. DerweeshIthaar H. Derweesh More articles by this author , Martha M. FaradayMartha M. Faraday More articles by this author , Jihad H. KaoukJihad H. Kaouk Financial interest and/or other relationship with Endocare, Intuitive Surgical. More articles by this author , Raymond J. LeveilleeRaymond J. Leveillee Financial interest and/or other relationship with Pluromed, LMA Urology-Suisee, Boston Scientific, ACMI, Applied Medial, ValleyLab, Ethicon, Intuitive Surgical. More articles by this author , Surena F. MatinSurena F. Matin Financial interest and/or other relationship with Johnson & Johnson Wound Management. More articles by this author , Paul RussoPaul Russo Financial interest and/or other relationship with Wilex AG. More articles by this author , and Robert G. UzzoRobert G. Uzzo Financial interest and/or other relationship with Pfizer, Bayer. More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2009.07.004AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail References 1 : Kidney. In: AJCC Cancer Staging Manual. Edited by . New York: Springer Verlag2002: 323. Google Scholar 2 : Cancer statistics, 2008. CA Cancer J Clin2008; 58: 71. Google Scholar 3 : Global increases in kidney cancer incidence, 1973–1992. Eur J Cancer Prev2002; 11: 171. Google Scholar 4 : Increased incidence of serendipitously discovered renal cell carcinoma. Urology1998; 51: 203. 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Link, Google Scholar American Urological Association Education and Research, Inc., Linthicum, Maryland© 2009 by American Urological AssociationFiguresReferencesRelatedDetailsCited byMillan B, Breau R, Bhindi B, Mallick R, Tanguay S, Finelli A, Lavallée L, Pouliot F, Rendon R, So A, Dean L, Lattouf J, Basappa N and Kapoor A (2022) A Comparison of Percutaneous Ablation Therapy to Partial Nephrectomy for cT1a Renal Cancers: Results from the Canadian Kidney Cancer Information SystemJournal of Urology, VOL. 208, NO. 4, (804-812), Online publication date: 1-Oct-2022.Campbell S, Uzzo R, Karam J, Chang S, Clark P and Souter L (2021) Renal Mass and Localized Renal Cancer: Evaluation, Management, and Follow-up: AUA Guideline: Part IIJournal of Urology, VOL. 206, NO. 2, (209-218), Online publication date: 1-Aug-2021.Campbell S, Clark P, Chang S, Karam J, Souter L and Uzzo R (2021) Renal Mass and Localized Renal Cancer: Evaluation, Management, and Follow-Up: AUA Guideline: Part IJournal of 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date: 1-Nov-2016.Larcher A, Capitanio U, Terrone C, Volpe A, De Angelis P, Dehó F, Fossati N, Dell’Oglio P, Antonelli A, Furlan M, Simeone C, Serni S, Carini M, Minervini A, Fiori C, Porpiglia F, Briganti A, Montorsi F and Bertini R (2016) Elective Nephron Sparing Surgery Decreases Other Cause Mortality Relative to Radical Nephrectomy Only in Specific Subgroups of Patients with Renal Cell CarcinomaJournal of Urology, VOL. 196, NO. 4, (1008-1013), Online publication date: 1-Oct-2016.Pierorazio P, Johnson M, Patel H, Sozio S, Sharma R, Iyoha E, Bass E and Allaf M (2016) Management of Renal Masses and Localized Renal Cancer: Systematic Review and Meta-AnalysisJournal of Urology, VOL. 196, NO. 4, (989-999), Online publication date: 1-Oct-2016.Moskowitz D, Chang J, Ziogas A, Anton-Culver H and Clayman R (2016) Treatment for T1a Renal Cancer Substratified by Size: “Less is More”Journal of Urology, VOL. 196, NO. 4, (1000-1007), Online publication date: 1-Oct-2016.Borgmann H, Reiss A, Kurosch 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No AccessJournal of Urology1 May 1948Intubated Ureterotomy: Experimental Work and Clinical Results1 David M. Davis, George H. Strong, and Willard M. Drake David M. DavisDavid M. Davis , George H. StrongGeorge H. Strong , and Willard M. DrakeWillard M. Drake View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)69449-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1948 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByChristman M, Kasturi S, Lambert S, Kovell R and Casale P (2018) Endoscopic Management and the Role of Double Stenting for Primary Obstructive MegauretersJournal of Urology, VOL. 187, NO. 3, (1018-1023), Online publication date: 1-Mar-2012.LOVACO F, SERRANO A, FERNÁNDEZ I, PÉREZ P and GONZÁLEZ-PERAMATO P (2018) ENDOURETEROTOMY BY INTRALUMINAL INVAGINATION FOR NONMALIGNANT URETEROINTESTINAL ANASTOMOTIC STRICTURES: DESCRIPTION OF A NEW SURGICAL TECHNIQUE AND LONG-TERM FOLLOWUPJournal of Urology, VOL. 174, NO. 5, (1851-1856), Online publication date: 1-Nov-2005.ANDREONI C, LIN H, OLWENY E, LANDMAN J, LEE D, BOSTWICK D and CLAYMAN R (2018) Comprehensive Evaluation of Ureteral Healing After Electrosurgical Endopyelotomy in a Porcine Model: Original Report and Review of the LiteratureJournal of Urology, VOL. 171, NO. 2, (859-869), Online publication date: 1-Feb-2004.MANDHANI A, KAPOOR R, ZAMAN W, KUMAR A, BHANDARI M and GAMBHIR S (2018) Is 2-Week Duration Sufficient for Stenting in Endopyelotomy?Journal of Urology, VOL. 169, NO. 3, (886-889), Online publication date: 1-Mar-2003.Watterson J, Sofer M, Wollin T, Nott L and Denstedt J (2018) Holmium: Yag Laser Endoureterotomy For Ureterointestinal StricturesJournal of Urology, VOL. 167, NO. 4, (1692-1695), Online publication date: 1-Apr-2002.KINN A (2018) URETEROPELVIC JUNCTION OBSTRUCTION: LONG-TERM FOLLOWUP OF ADULTS WITH AND WITHOUT SURGICAL TREATMENTJournal of Urology, VOL. 164, NO. 3 Part 1, (652-656), Online publication date: 1-Sep-2000.TAWFIEK E, LIU J and BAGLEY D (2018) URETEROSCOPIC TREATMENT OF URETEROPELVIC JUNCTION OBSTRUCTIONJournal of Urology, VOL. 160, NO. 5, (1643-1647), Online publication date: 1-Nov-1998.Goldfischer E and Gerber G (2018) Endoscopic Management of Ureteral StricturesJournal of Urology, VOL. 157, NO. 3, (770-775), Online publication date: 1-Mar-1997.Conlin M, Gomella L and Bagley D (2018) Endoscopic Ureteroureterostomy for Obliterated Ureteral SegmentsJournal of Urology, VOL. 156, NO. 4, (1394-1399), Online publication date: 1-Oct-1996.Gupta M and Smith A (2018) Commentary on Incisions, Stents and HealingJournal of Urology, VOL. 156, NO. 3, (866-866), Online publication date: 1-Sep-1996.Nadler R, Rao G, Pearle M, Nakada S and Clayman R (2018) Acucise Endopyelotomy: Assessment of Long-term DurabilityJournal of Urology, VOL. 156, NO. 3, (1094-1098), Online publication date: 1-Sep-1996.Gardner S, Wolf S, Nakada S, Moon Y, Figenshau R, Pearle M, Soble J, Humphrey P and Clayman R (2018) The Unintubated Ureterotomy Endourologically RevisitedJournal of Urology, VOL. 156, NO. 3, (1160-1163), Online publication date: 1-Sep-1996.Strup S and Bagley D (2018) Endoscopic 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A (2018) Percutaneous Surgery for Ureteropelvic Junction Obstruction (Endopyelotomy): Technique and Early ResultsJournal of Urology, VOL. 135, NO. 1, (26-28), Online publication date: 1-Jan-1986.Segura J (2018) Editorial CommentJournal of Urology, VOL. 135, NO. 1, (28-28), Online publication date: 1-Jan-1986.Duckett J and Pfister R (2018) Ureterocalicostomy for Renal SalvageJournal of Urology, VOL. 128, NO. 1, (98-101), Online publication date: 1-Jul-1982.Diamond D and Marshall F (2018) The Diagnosis and Management of Spontaneous Rupture of the UreterJournal of Urology, VOL. 128, NO. 4, (808-810), Online publication date: 1-Oct-1982.Raney A, Decaestecker J, Bogaev J, Lewis P and Zimskind P (2018) Free Full-Thickness Pelvic Graft: Experimental Repair of Ureter and Ureteropelvic JunctionJournal of Urology, VOL. 105, NO. 1, (59-62), Online publication date: 1-Jan-1971.Moore C and Diaz-ball F (2018) Management of Ureteral Stricture Secondary to TuberculosisJournal of Urology, VOL. 102, NO. 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Volume 59Issue 5May 1948Page: 851-859 Advertisement Copyright & Permissions© 1948 by The American Urological Association Education and Research, Inc.MetricsAuthor Information David M. Davis More articles by this author George H. Strong More articles by this author Willard M. Drake More articles by this author Expand All Advertisement PDF DownloadLoading ...

No AccessJournal of Urology1 Oct 1960Bladder Tumors and Associated Proliferative Mucosal Lesions Richard B. Eisenberg, Russell B. Roth, and Michael H. Schweinsberg Richard B. EisenbergRichard B. Eisenberg , Russell B. RothRussell B. Roth , and Michael H. SchweinsbergMichael H. Schweinsberg View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)65589-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1960 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited by Cheng L, Lopez-Beltran A, MacLennan G, Montironi R and Bostwick D (2020) Neoplasms of the Urinary Bladder Urologic Surgical Pathology, 10.1016/B978-0-323-54941-7.00006-2, (230-321.e19), . 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Volume 173Issue 6June 2005Page: 1991-2000 Advertisement Copyright & Permissions© 2005 by American Urological Association, Inc.MetricsAuthor Information GLENN M. PREMINGER Financial interest and/or other relationship with Boston Scientific-Urology, Olympus American, Inc., Mission Pharmacal and Applied Urology. More articles by this author DEAN G. ASSIMOS Financial interest and/or other relationship with Medical Reviews in Urology, Ixion and Boston Scientific. More articles by this author JAMES E. LINGEMAN Financial interest and/or other relationship with Olympus, Lumenis, Thermatrix, Midstate Mobile Lithotripsy, LP, Progressive Thermotherapy, LP, Storz Medical and Boston Scientific. More articles by this author STEPHEN Y. NAKADA Financial interest and/or other relationship with Cook Urology, Applied Medical and Boston Scientific. More articles by this author MARGARET S. PEARLE Financial interest and/or other relationship with Applied Medical, Percutaneous Systems, Inc., Cook Urology and Boston Scientific. More articles by this author J. STUART WOLF More articles by this author Expand All Advertisement PDF downloadLoading ...

No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Oct 2002Transurethral Holmium Laser Enucleation Versus Transvesical Open Enucleation for Prostate Adenoma Greater Than 100 gm.: A Randomized Prospective Trial of 120 Patients Rainer M. Kuntz and Karin Lehrich Rainer M. KuntzRainer M. Kuntz More articles by this author and Karin LehrichKarin Lehrich More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64475-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Prostate adenomas greater than 100 gm. have traditionally been treated with open prostatectomy. This procedure may involve considerable blood loss, morbidity, prolonged hospital stay and recovery time. The high powered holmium:YAG laser can be used endoscopically to enucleate obstructing prostatic tissue in a relatively bloodless manner. The technique of transurethral holmium laser enucleation of the prostate is compared to open prostatectomy for the surgical management of large prostate adenomas in a prospective randomized study. Materials and Methods: A total of 120 urodynamically obstructed patients with a prostate larger than 100 gm. on transrectal ultrasound were randomized to undergo holmium laser enucleation of the prostate or open prostatectomy. All patients were assessed preoperatively and 1, 3 and 6 months postoperatively. Patient baseline characteristics, perioperative data and postoperative outcome were compared. All complications were noted. Results: Holmium laser enucleation of the prostate and open prostatectomy resulted in a similar and significant improvement in American Urological Association symptom scores, peak urinary flow rates and post-void residual urine volumes. Operating time was significantly longer in the holmium group but blood loss was significantly less, and catheterization time and hospital stay were significantly shorter. Effects on continence and potency were similar in both groups but adverse events were less frequent in the holmium group. None of the holmium group patients needed blood transfusions in contrast to 8 patients in the prostatectomy group. Conclusions: Holmium laser enucleation of the prostate and open prostatectomy are equally effective procedures for removal of large prostatic adenomas. Holmium laser enucleation resulted in significantly less perioperative morbidity and may become the endourological alternative to open prostatectomy. References 1 : Holmium laser enucleation for prostate adenoma greater than 100 gm.: comparison to open prostatectomy. J Urol2001; 165: 459. Link, Google Scholar 2 : Laser prostatectomy with the holmium: YAG laser. Tech Urol1995; 1: 217. 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No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jan 2003The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients GYAN PAREEK, MARIA SHEVCHUK, NOEL A. ARMENAKAS, LJILJANA VASJOVIC, DAVID A. HOCHBERG, JAY B. BASILLOTE, and JOHN A. FRACCHIA GYAN PAREEKGYAN PAREEK , MARIA SHEVCHUKMARIA SHEVCHUK , NOEL A. ARMENAKASNOEL A. ARMENAKAS , LJILJANA VASJOVICLJILJANA VASJOVIC , DAVID A. HOCHBERGDAVID A. HOCHBERG , JAY B. BASILLOTEJAY B. BASILLOTE , and JOHN A. FRACCHIAJOHN A. FRACCHIA View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64025-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Several studies have confirmed the benefit of finasteride in limiting hematuria from benign prostatic hyperplasia. Vascular endothelial growth factor (VEGF), a potent stimulator of angiogenesis, and microvessel density have been independently evaluated in the mechanism of decreased bleeding observed in patients treated with finasteride. We evaluated the expression of VEGF and suburethral prostatic microvessel density in patients with benign prostatic hyperplasia treated with finasteride. Materials and Methods: The study included 24 patients undergoing prostatic surgery for benign disease, of whom 12 were given finasteride for a minimum of 6 weeks before surgery and the remaining 12 served as controls. Sections from the prostatic urothelium and hyperplastic prostate were individually stained for CD34 specific for nascent blood vessels and VEGF. Analysis of each specimen was performed in a blinded fashion. Microvessel density was calculated by counting the number of positively stained blood vessels on 10 consecutive, nonoverlapping, high power fields within the suburethral and hyperplastic prostate compartments. VEGF expression was examined by immunohistochemistry. Statistical analysis of the results was performed using Student's t test. Results: Prostatic suburethral VEGF expression and microvessel density were significantly lower in the finasteride group compared to controls (p <0.05). Differences in VEGF expression and microvessel density at the level of the hyperplastic prostate were not found to be significantly different between the 2 groups. Conclusions: Decreased expression of VEGF by finasteride inhibits angiogenesis and significantly decreases microvessel density in prostatic suburethral tissue. This sequential relationship provides histochemical insight into the mechanism by which finasteride reduces prostatic urethral bleeding. 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No AccessJournal of Urology1 Apr 1956Recurrence of Bladder Tumors by Surgical Implantation Frank Hinman Frank HinmanFrank Hinman View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)66866-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Recurrence of Bladder Tumors by Surgical Implantation." The Journal of Urology, 75(4), pp. 695–696 © 1956 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited by Sionov B, Tsivian M, Bakaleyschik P, Sidi A and Tsivian A (2022) Oncological safety of simultaneous transurethral resection of high-grade urothelial carcinoma of the bladder and benign prostatic hyperplasiaArab Journal of Urology, 10.1080/2090598X.2022.2142365, (1-6) Savvides E, Pyrgidis N, Langas G, Symeonidis E, Dimitriadis G and Sountoulides P (2022) Concomitant Endoscopic Surgery for Bladder Tumors and Prostatic Obstruction: Are We Safely Hitting Two Birds with One Stone? 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Volume 75Issue 4April 1956Page: 695-696 Advertisement Copyright & Permissions© 1956 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Frank Hinman More articles by this author Expand All Advertisement PDF downloadLoading ...

No AccessJournal of Urology1 Mar 1966Epididymitis: A Review of 610 cases B.T. Mittemeyer, K.W. Lennox, and A.A. Borski B.T. MittemeyerB.T. Mittemeyer Present address: Walter Reed Army Medical Center, Washington, D.C. More articles by this author , K.W. LennoxK.W. Lennox Present address: U. S. Army Hospital, Fort Leonard Wood, Missouri. More articles by this author , and A.A. BorskiA.A. Borski Present address: Hg. 4th A. D. Office of the Surgeon, APO, New York 09326. More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)63468-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1966 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited by Shen F, Kapoor J, Moir D and Gyomber D (2022) Testicular infarction and spontaneous scrotal rupture secondary to acute epididymo-orchitisBMJ Case Reports, 10.1136/bcr-2021-247028, VOL. 15, NO. 3, (e247028), Online publication date: 1-Mar-2022. Bonar A, Pramod S, Noegroho B and Mustafa A (2022) Testicular ischemia in patient with acute epididymitis: A rare caseUrology Case Reports, 10.1016/j.eucr.2021.101882, VOL. 40, (101882), Online publication date: 1-Jan-2022. Chirwa M, Davies O, Castelino S, Mpenge M, Nyatsanza F, Sethi G, Shabbir M and Rayment M (2021) United Kingdom British association for sexual health and HIV national guideline for the management of epididymo-orchitis, 2020International Journal of STD & AIDS, 10.1177/09564624211003761, VOL. 32, NO. 10, (884-895), Online publication date: 1-Sep-2021. Zambrano N and Fullá J (2021) Epididymitis and Orchitis A Clinical Guide to Urologic Emergencies, 10.1002/9781119021506.ch17, (232-243), Online publication date: 6-Aug-2021. Tan J, Tian M, Zhao F, Deng S, Jin P, Wang Y, Wen H, Qin X and Gong Y (2021) An Investigation of the Male Genitourinary Abscess Originated from Urinary Tract in a Tertiary Hospital, Shanghai, China, from 2004 to 2019Infection and Drug Resistance, 10.2147/IDR.S298250, VOL. 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No AccessJournal of UrologyCLINICAL UROLOGY: ORIGINAL ARTICLES1 Sep 2002Impact of Previous Local Treatment for Prostate Cancer on Subsequent Metastatic Disease Ian M. Thompson, Catherine Tangen, Joseph Basler, and E. David Crawford Ian M. ThompsonIan M. Thompson More articles by this author , Catherine TangenCatherine Tangen More articles by this author , Joseph BaslerJoseph Basler More articles by this author , and E. David CrawfordE. David Crawford More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64562-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Metastatic prostate cancer, which is the precursor of most deaths from the disease, is treated most commonly with hormonal therapy. Generally the primary tumor is never treated. Due to evidence that controlling other primary neoplasms affects patient survival we examined the impact of radical prostatectomy and radiotherapy on the outcome in patients with metastatic prostate cancer in the context of a randomized clinical trial. Materials and Methods: Southwest Oncology Group Study 8894 randomized 1,286 men with metastatic prostate cancer to orchiectomy and placebo or orchiectomy and flutamide. We performed proportional hazards analysis of variables previously identified to have a significant impact on survival. In this analysis we determined the impact of previous radical prostatectomy or radiotherapy on survival. Results: Previous radical prostatectomy in patients with metastatic prostate cancer was associated with a statistically significant decrease in the risk of death (hazard ratio 0.77, 95% confidence interval 0.53 to 0.89) relative to those who did not undergo earlier prostatectomy. Conversely previous radiotherapy was associated with a greater risk of death in those who had previously undergone prostatectomy and those who received no definitive earlier therapy. Conclusions: It must be stressed that this intriguing observation was a secondary analysis of a phase III study. Nevertheless, it raises the question of whether control of the primary tumor impacts the ultimate outcome in patients with advanced prostate cancer. The suggestion of the role of radical prostatectomy in locally advanced prostate cancer, the now established role of extirpative therapy for renal cell carcinoma and the suggestion of this phenomenon in ovarian carcinoma should prompt further evaluation of this finding in other data sets. It may provide new opportunities for clinical trials. References 1 : Cancer statistics 2001. CA Cancer J Clin2001; 5: 15. Crossref, Google Scholar 2 : Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. New Engl J Med1998; 339: 1036. 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Volume 13, (565-571) Koura M, Shiota M, Ueda S, Matsumoto T, Kobayashi S, Monji K, Kashiwagi E, Takeuchi A, Inokuchi J, Shiga K, Yokomizo A and Eto M (2021) Prognostic impact of prior local therapy in castration-resistant prostate cancerJapanese Journal of Clinical Oncology, 10.1093/jjco/hyab019, VOL. 51, NO. 7, (1142-1148), Online publication date: 1-Jul-2021. 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Kamba T, Kamoto T, Maruo S, Kikuchi T, Shimizu Y, Namiki S, Fujimoto K, Kawanishi H, Sato F, Narita S, Satoh T, Saito H, Sugimoto M, Teishima J, Masumori N, Egawa S, Sakai H, Okada Y, Terachi T and Ogawa O (2016) A phase III multicenter, randomized, controlled study of combined androgen blockade with versus without zoledronic acid in prostate cancer patients with metastatic bone disease: results of the ZAPCA trialInternational Journal of Clinical Oncology, 10.1007/s10147-016-1037-2, VOL. 22, NO. 1, (166-173), Online publication date: 1-Feb-2017. Kim J, Park J and Ham W (2017) The role of metastasis-directed therapy and local therapy of the primary tumor in the management of oligometastatic prostate cancerInvestigative and Clinical Urology, 10.4111/icu.2017.58.5.307, VOL. 58, NO. 5, (307), . 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No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Nov 2002A Randomized Prospective Blinded Study Validating Acquistion of Ureteroscopy Skills Using A Computer Based Virtual Reality Endourological Simulator JAMES D. WATTERSON, DARREN T. BEIKO, JAMES K. KUAN, and JOHN D. DENSTEDT JAMES D. WATTERSONJAMES D. WATTERSON , DARREN T. BEIKODARREN T. BEIKO , JAMES K. KUANJAMES K. KUAN , and JOHN D. DENSTEDTJOHN D. DENSTEDT View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64265-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Surgical simulation has emerged in the last decade as a potential tool for aiding acquisition of technical skills, including anesthesia protocols, trauma management, cardiac catheterization and laparoscopy. We evaluate and validate the use of a computer based ureteroscopy simulator (URO Mentor, Simbionix Ltd., Lod, Israel) in the acquisition of basic ureteroscopic skills. Materials and Methods: We assessed 20 novice trainees for the ability to perform basic ureteroscopic tasks on a computer based ureteroscopy simulator. Participants were randomized to receive individualized mentored instruction or no additional training, and subsequently underwent post-testing. Pre-training and post-training improvement in performance was assessed by objective simulator based measurements. Subjective overall performance was rated using a validated endourological global rating scale by an observer blinded to subject training status. Results: Demographics and pre-test scores were similar between groups. Post-testing revealed a significant effect of training on objective and subjective measurements. Spearman rank correlation demonstrated a significant association between objective simulator based measurements and the endourological global rating scale. Conclusions: Use of a computer based ureteroscopy simulator resulted in rapid acquisition of ureteroscopic skills in trainees with no prior surgical training. Results of this study demonstrate the use of a virtual reality ureteroscopy simulator in endourological training. Correlation of simulator based measurements with a previously validated endourological global rating scale provides initial validation of the ureteroscopy simulator for the assessment of ureteroscopic skills. References 1 : Anaesthetic simulators: training for the broader health-care profession. Aust N Z J Surg2000; 70: 735. Crossref, Medline, Google Scholar 2 : Use of a human patient simulator in the development of resident trauma management skills. J Trauma2001; 51: 17. Crossref, Medline, Google Scholar 3 : The virtual reality arthroscopy training simulator. 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No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jan 2003Urethral Stricture Repair With an Off-the-shelf Collagen Matrix ABDEL W. EL-KASSABY, ALAN B. RETIK, JAMES J. YOO, and ANTHONY ATALA ABDEL W. EL-KASSABYABDEL W. EL-KASSABY , ALAN B. RETIKALAN B. RETIK , JAMES J. YOOJAMES J. YOO , and ANTHONY ATALAANTHONY ATALA View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64060-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: In select patients with urethral strictures in whom genital skin is insufficient alternative tissues are needed for urethral reconstruction. We explored the feasibility of using a bladder submucosa collagen based inert matrix as a free graft substitute for urethral stricture repair. Materials and Methods: A total of 28 patients 22 to 61 years old with a diagnosis of urethral stricture underwent reconstructive surgery using a collagen based inert matrix for urethral repair. The inert collagen matrix was trimmed to size as needed for each patient and the neourethra was created by anastomosing the matrix in an onlay fashion to the urethral plate with continuous 6-zero absorbable sutures. The size of the created neourethra ranged from 1.5 to 16 cm. A voiding history, physical examination, retrograde urethrography, uroflowmetry and cystoscopic examinations were performed preoperatively and postoperatively. Random urethral biopsies were also performed. Results: After a 36 to 48-month followup (mean 37) 24 of the 28 patients had a successful outcome. The remaining 4 patients had a slight caliber decrease at the anastomotic sites on urethrography. A subcoronal fistula developed in 1 patient which closed spontaneously 1 year after repair. Mean maximum urine flow rate increased from the preoperative value of 9 ± 1.29 to 19.7 ± 3.07 ml. per second postoperatively. Cystoscopic studies revealed adequate caliber conduits and normal appearing urethral tissues. Histological examination of the biopsy specimens showed the typical urethral stratified epithelium. Conclusions: Use of an off-the-shelf collagen inert matrix appears to be beneficial for patients with urethral strictures and obviates the need for obtaining an autologous graft, thus eliminating donor site morbidity. References 1 : Preface. Urethral reconstruction. Urol Clin North Am2002; 29: 2. Crossref, Google Scholar 2 : Neourethra with rectum, posterior sagittal approach. In: Reconstructive and Plastic Surgery of the External Genitalia: Adult and Pediatric. Edited by . Philadelphia: W. B. Saunders Co.1999. Google Scholar 3 : Autologous buccal mucosa graft for hypospadias repair: an initial report. J Urol1992; 147: 1081. 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No AccessJournal of UrologyCLINICAL UROLOGY: ORIGINAL ARTICLES1 Sep 2002Laparoscopic and Robot Assisted Radical Prostatectomy: Establishment of a Structured Program and Preliminary Analysis of Outcomes Mani Menon, Alok Shrivastava, Ashutosh Tewari, Richard Sarle, Ashok Hemal, James O. Peabody, and Guy Vallancien Mani MenonMani Menon , Alok ShrivastavaAlok Shrivastava , Ashutosh TewariAshutosh Tewari , Richard SarleRichard Sarle , Ashok HemalAshok Hemal , James O. PeabodyJames O. Peabody , and Guy VallancienGuy Vallancien View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64548-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The technique of laparoscopic radical prostatectomy is difficult to master and is associated with a steep learning curve. We hypothesized that a structured approach to establishing a laparoscopic prostatectomy program would diminish complications during the learning process and that robotic technology would be useful in learning the operation. Materials and Methods: A structured laparoscopic radical prostatectomy program was introduced at the Vattikuti Urology Institute on October 23, 2000. One of 2 surgeons with a combined experience of more than 500 laparoscopic radical prostatectomies performed or supervised the first prostatectomies, training a third surgeon with extensive "open" surgical skills but no laparoscopic experience. The "trained" surgeon then started performing the operation independently with robotic assistance. The results of this approach were analyzed at the end of 12 months. Results: We performed 48 laparoscopic radical prostatectomies and 50 robot assisted prostatectomies within the 12-month period. The preoperative and intraoperative demographical variables were comparable in both groups as were the operative times, changes in hemoglobin concentrations, durations of hospitalization, positive margin rates and overall complication rates. All measured parameters were comparable to the "best-in-class" values for laparoscopic radical prostatectomy reported in the literature. Conclusions: A structured approach minimizes complications during the establishment of laparoscopic radical prostatectomy program. Robotic assistance helps skilled "open" surgeons learn the technique of laparoscopic radical prostatectomy. References 1 : Laparoscopic radical prostatectomy: initial short-term experience. Urology1997; 50: 854. Crossref, Medline, Google Scholar 2 : Laparoscopic radical prostatectomy: the Montsouris technique. J Urol2000; 163: 1643. Link, Google Scholar 3 : Laparoscopic radical prostatectomy: preliminary results. Urology2000; 55: 630. 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No AccessJournal of Urology1 Dec 1955The First Reported Cases of Human Bladder Tumors Due to a New Carcinogen—Xenylamine W.F. Melick, H.M. Escue, J.J. Naryka, R.A. Mezera, and Elmer P. Wheeler W.F. MelickW.F. Melick , H.M. EscueH.M. Escue , J.J. NarykaJ.J. Naryka , R.A. MezeraR.A. Mezera , and Elmer P. WheelerElmer P. Wheeler View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)67344-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1955 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited by Amin M, Comperat E, Epstein J, True L, Hansel D, Paner G, Al-Ahmadie H, Baydar D, Bivalacqua T, Brimo F, Cheng L, Cheville J, Dalbagni G, Falzarano S, Gordetsky J, Guo C, Gupta S, Hes O, Iyer G, Kaushal S, Kunju L, Magi-Galluzzi C, Matoso A, Netto G, Osunkoya A, Pan C, Pivovarcikova K, Raspollini M, Reis H, Rosenberg J, Roupret M, Shah R, Shariat S, Trpkov K, Weyerer V, Zhou M, McKenney J and Reuter V (2021) The Genitourinary Pathology Society Update on Classification and Grading of Flat and Papillary Urothelial Neoplasia With New Reporting Recommendations and Approach to Lesions With Mixed and Early Patterns of NeoplasiaAdvances in Anatomic Pathology, 10.1097/PAP.0000000000000308, VOL. 28, NO. 4, (179-195), Online publication date: 1-Jul-2021. 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No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jan 2003A Retrospective Analysis of 153 Patients Treated With or Without Intravesical Bacillus Calmette-Guerin for Primary Stage T1 Grade 3 Bladder Cancer: Recurrence, Progression and Survival OSAMA SHAHIN, GEORGE N. THALMANN, CYRILL RENTSCH, L. MAZZUCCHELLI, and U.E. STUDER OSAMA SHAHINOSAMA SHAHIN , GEORGE N. THALMANNGEORGE N. THALMANN , CYRILL RENTSCHCYRILL RENTSCH , L. MAZZUCCHELLIL. MAZZUCCHELLI , and U.E. STUDERU.E. STUDER View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64044-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We retrospectively evaluated the long-term outcome in patients with newly diagnosed stage T1 grade 3 bladder cancer treated with transurethral resection with or without intravesical bacillus Calmette-Guerin (BCG). Materials and Methods: Of 153 patients with a median age of 67 years (range 36 to 88) and a male-to-female ratio of 4:1 we treated 92 with transurethral bladder resection and additional BCG, and 61 with transurethral bladder resection alone. BCG was administered intravesically as 120 mg. BCG Pasteur F dissolved in 50 ml. saline, retained for up to 2 hours weekly for 6 weeks and repeated as necessary. Results: Median followup was 5.3 years (range 0.4 to 18.2). Disease recurred in 70% of the patients treated with BCG and in 75% treated with transurethral resection alone. Median time to recurrence was 38 and 22 months for BCG and resection alone (p = 0.19). Tumor progressed in 33% of patients with BCG and in 36% with resection alone. Deferred cystectomy was performed in 29% of the patients with BCG and in 31% with resection alone. Overall and disease specific survival did not differ significantly. Conclusions: Our results suggest that intravesical BCG therapy after transurethral bladder resection for stage T1 grade 3 bladder cancer may delay the time to recurrence and cystectomy but it does not substantially alter the final outcome. Our findings reflect the rule of 30% for stage T1 grade 3 cancer, namely approximately 30% of patients never have recurrence, 30% ultimately die of metastatic disease and 30% require deferred cystectomy. References 1 : Treatment of superficial bladder tumors achievements and needs. The EORTC Genitourinary Group. Eur Urol2000; 37: 1. Crossref, Medline, Google Scholar 2 : Radical cystectomy for high risk patients with superficial bladder cancer in the era of orthotopic urinary reconstruction. Cancer1995; 76: 833. Crossref, Medline, Google Scholar 3 : Stage T1, grade 3 transitional cell carcinoma of the bladder: an unfavorable tumor?. J Urol1984; 137: 39. 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Link, Google Scholar From the Department of Urology and Institute of Pathology, University of Bern, Inselspital, Bern, Switzerland© 2003 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited by Cole K, Al-Kadhimi Z and Talmadge J (2023) Highlights into historical and current immune interventions for cancerInternational Immunopharmacology, 10.1016/j.intimp.2023.109882, VOL. 117, (109882), Online publication date: 1-Apr-2023. 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No AccessJournal of UrologyClinical Urology: Original Article1 Aug 1995Randomized Prospective Study Comparing Radical Prostatectomy Alone Versus Radical Prostatectomy Preceded by Androgen Blockage in Clinical Stage B2 (T2bNxM0) Prostate Cancer Mark S. Soloway, Roohollah Sharifi, Zev Wajsman, David McLeod, David P. Jr. Wood, and Antonio for the Lupron Depot Neoadjuvant Prostate Cancer Study Group* Puras-Baez Mark S. SolowayMark S. Soloway , Roohollah SharifiRoohollah Sharifi , Zev WajsmanZev Wajsman , David McLeodDavid McLeod , David P. Jr. WoodDavid P. Jr. Wood , and Antonio for the Lupron Depot Neoadjuvant Prostate Cancer Study Group* Puras-BaezAntonio for the Lupron Depot Neoadjuvant Prostate Cancer Study Group* Puras-Baez View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)67067-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Nonrandomized clinical trials have suggested that preoperative androgen deprivation can decrease the likelihood of positive surgical margins in patients with clinically localized prostate cancer. A multicenter prospective randomized trial compared radical prostatectomy alone to radical prostatectomy after 3 months of leuprolide acetate depot and flutamide in patients with stage cT2bNxM0 prostate cancer and a serum prostate specific antigen level less than 50 ng./ml. Materials and Methods: We randomized 149 patients to undergo androgen deprivation and 138 to undergo lymphadenectomy with (137) or without (1) prostatectomy. Of the 154 patients randomized to the surgery alone group 144 underwent pelvic node dissection with (138) or without (6) prostatectomy. Results: There was no statistically significant difference between the 2 groups in operating time, blood loss, need for transfusion, postoperative morbidity or length of hospital stay. There were 4 rectal and 2 ureteral injuries in the surgery alone group and none in the pretreatment group (p less than 0.05). Patients who received androgen deprivation preoperatively had a significantly lower rate of capsule penetration (47 percent versus 78 percent, p less than 0.001), positive surgical margins (18 percent versus 48 percent, p less than 0.001) and tumor at the urethral margin (6 percent versus 17 percent, p less than 0.01). Conclusions: Long-term followup data will be needed to determine whether there will be a lower incidence of biochemical relapse as determined by prostate specific antigen, local recurrence or metastasis, with an improvement in patient survival. References 1 : The contemporary incidence of lymph node metastases in prostate cancer: implications for laparoscopic lymph node dissection. J. Urol.1993; 149: 1488. Link, Google Scholar 2 : Lower incidence of unsuspected lymph node metastases in 521 consecutive patients with clinically localized prostate cancer. J. Urol.1992; 147: 1574. Link, Google Scholar 3 : The use of prostate specific antigen, clinical stage and Gleason score to predict pathological stage in men with localized prostate cancer. J. Urol.1993; 150: 110. Link, Google Scholar 4 : Analysis of risk factors associated with prostate cancer extension to the surgical margin and pelvic node metastasis at radical prostatectomy. J. Urol.1993; 150: 1845. 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Volume 154Issue 2August 1995Page: 424-428 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.MetricsAuthor Information Mark S. Soloway More articles by this author Roohollah Sharifi More articles by this author Zev Wajsman More articles by this author David McLeod More articles by this author David P. Jr. Wood More articles by this author Antonio for the Lupron Depot Neoadjuvant Prostate Cancer Study Group* Puras-Baez More articles by this author Expand All Advertisement PDF downloadLoading ...

No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jan 2003Intravesical Bacillus Calmette-Guerin Versus Mitomycin C For Superficial Bladder Cancer: A Formal Meta-Analysis of Comparative Studies on Recurrence and Toxicity A. BÖHLE, D. JOCHAM, and P.R. BOCK A. BÖHLEA. BÖHLE Financial interest and/or other relationship with Aventis Pasteur, Ltd. More articles by this author , D. JOCHAMD. JOCHAM Financial interest and/or other relationship with Aventis Pasteur, Ltd. More articles by this author , and P.R. BOCKP.R. BOCK Financial interest and/or other relationship with Aventis Pasteur, Ltd. More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64043-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We compare the therapeutic efficacy and toxicity of intravesical bacillus Calmette-Guerin (BCG) with mitomycin C on recurrence of stages Ta and T1 bladder carcinoma. Materials and Methods: Combined published and unpublished data from comparative studies on BCG versus mitomycin C for superficial bladder carcinoma considering possible confounding factors were analyzed. Odds ratio (OR) and its 95% CI were used as primary effect size estimate. Toxicity data were evaluated descriptively. Results: In 11 eligible clinical trials 1,421 patients were treated with BCG and 1,328 were treated with mitomycin C. Within the overall median followup time of 26 months 38.6% of the patients in the BCG group and 46.4% of those in the mitomycin C group had tumor recurrence. In 7 of 11 studies BCG was significantly superior to mitomycin C, in 3 studies no significant difference was found, while in 1 study mitomycin C was significantly superior to BCG. An overall statistically significant superiority of BCG versus mitomycin C efficacy in reducing tumor recurrence was detected (OR 0.56, 95% CI 0.38 to 0.84, p = 0.005). In the subgroup treated with BCG maintenance all 6 individual studies showed a significant superiority of BCG over mitomycin C (OR 0.43, 95% CI 0.35 to 0.53, p <0.001). In 4 of the 5 studies with reported data on toxicity BCG associated cystitis was significantly more frequent than in the mitomycin C group (53.8% versus 39.2%). The combined cystitis OR was 1.81 (95% CI 1.48 to 2.23, p <0.001). The OR for cystitis in the BCG maintenance group did not significantly differ from that in the nonmaintenance therapy group. Conclusions: The results suggest superiority of BCG over mitomycin C for prevention of tumor recurrences in the combined data and particularly in the BCG maintenance treatment subgroup, irrespective of the actual (intermediate or high) tumor risk status. The toxicity with BCG is higher but does not differ between BCG maintenance and nonmaintenance groups. References 1 : A combined analysis of European Organization for Research and Treatment of Cancer and Medical Research Council randomized clinical trials for the prophylactic treatment of stage TaT1 bladder cancer. J Urol1996; 156: 1934. Link, Google Scholar 2 : Bladder cancer clinical guidelines panel summary report on the management of nonmuscle invasive bladder cancer (stages Ta, T1 and TIS). J Urol1999; 162: 1697. Link, Google Scholar 3 : Guidelines on bladder cancer. Eur Urol2002; 41: 105. 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No AccessJournal of UrologyInvestigative Urology1 Sep 1998CONDITIONING FILM DEPOSITION ON URETERAL STENTS AFTER IMPLANTATION CHRISTINA TIESZER, GREGOR REID, and JOHN DENSTEDT CHRISTINA TIESZERCHRISTINA TIESZER More articles by this author , GREGOR REIDGREGOR REID More articles by this author , and JOHN DENSTEDTJOHN DENSTEDT More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)62825-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Three types of ureteral stents were used in a study of 53 patients. Following extracorporeal shock wave lithotripsy, the stents were implanted and retained for periods of between 3 and 40 days. Each patient received daily antibiotic therapy with either ciprofloxacin or trimethoprim. After removal, the devices were analyzed for adherent bacteria and encrustations. The study showed that a conditioning film became deposited onto the stents upon implantation, changing the surface characteristics of the biomaterials. Dense encrustations were found to be least on a low surface energy device. No differences were found related to patient age and gender or duration of stent insertion. Flakiness and apparent sloughing of the stent surfaces was observed in some devices, raising concerns as to what actually happens to medical devices when exposed to the host urinary tract. Bacteria were recovered from the urine of three patients and the stents of four patients treated with trimethoprim. Five stents had bacterial biofilms detected by SEM. The actual clinical end-point was not the focus of this study, but no patients became septic. Our goal was to demonstrate conclusively in humans that medical devices do develop conditioning films upon implantation, and that they can be susceptible to bacterial colonization even during antibiotic treatments. 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Sofer M and Denstedt J (2000) Encrustation of biomaterials in the urinary tractCurrent Opinion in Urology, 10.1097/00042307-200011000-00005, VOL. 10, NO. 6, (563-569), Online publication date: 1-Nov-2000. Hessen M, Zuckerman J and Kaye D (2014) Infections Associated with Foreign Bodies in the Urinary Tract Infections Associated with Indwelling Medical Devices, 10.1128/9781555818067.ch16, (325-344) Volume 160Issue 3 Part 1September 1998Page: 876-881 Advertisement Copyright & Permissions© 1998 by American Urological Association, Inc.Metrics Author Information CHRISTINA TIESZER More articles by this author GREGOR REID More articles by this author JOHN DENSTEDT More articles by this author Expand All Advertisement PDF downloadLoading ...