搜索结果：TH open : companion journal to thrombosis and haemostasis

Subclinical leaflet thrombosis (SLT) is a potentially serious complication of aortic valve replacement with a bioprosthetic valve in which blood clots form on the replacement valve. SLT is associated with increased risk of transient ischemic attacks and strokes and can progress to clinical leaflet thrombosis. SLT following aortic valve replacement also may be related to subsequent structural valve deterioration, which can impair the durability of the valve replacement. Because of the difficulty in clinical imaging of SLT, models are needed to determine the mechanisms of SLT and could eventually predict which patients will develop SLT. To this end, we develop methods to simulate leaflet thrombosis that combine fluid-structure interaction and a simplified thrombosis model that allows for deposition along the moving leaflets. Additionally, this model can be adapted to model deposition or absorption along other moving boundaries. We present convergence results and quantify the model's ability to realize changes in valve opening and pressures. These new approaches are an important advancement in our tools for modeling thrombosis in which they incorporate both adhesion to the surface of

In recent years, increased stakeholder pressure to transition research to Open Access has led to many journals converting, or 'flipping', from a closed access (CA) to an open access (OA) publishing model. Changing the publishing model can influence the decision of authors to submit their papers to a journal, and increased article accessibility may influence citation behaviour. In this paper we aimed to understand how flipping a journal to an OA model influences the journal's future publication volumes and citation impact. We analysed two independent sets of journals that had flipped to an OA model, one from the Directory of Open Access Journals (DOAJ) and one from the Open Access Directory (OAD), and compared their development with two respective control groups of similar journals. For bibliometric analyses, journals were matched to the Scopus database. We assessed changes in the number of articles published over time, as well as two citation metrics at the journal and article level: the normalised impact factor (IF) and the average relative citations (ARC), respectively. Our results show that overall, journals that flipped to an OA model increased their publication output compared

In recent years, increased stakeholder pressure to transition research to Open Access has led to many journals "flipping" from a toll access to an open access publishing model. Changing the publishing model can influence the decision of authors to submit their papers to a journal, and increased article accessibility may influence citation behaviour. The aim of this paper is to show changes in the number of published articles and citations after the flipping of a journal. We analysed a set of 171 journals in the Web of Science (WoS) which flipped to open access. In addition to comparing the number of articles, average relative citation (ARC) and normalized impact factor (IF) are applied, respectively, as bibliometric indicators at the article and journal level, to trace the transformation of flipped journals covered. Our results show that flipping mostly has had positive effects on journal's IF. But it has had no obvious citation advantage for the articles. We also see a decline in the number of published articles after flipping. We can conclude that flipping to open access can improve the performance of journals, despite decreasing the tendency of authors to submit their articles a

Overlay journals are characterised by their articles being published on open access repositories, often already starting in their initial preprint form as a prerequisite for submission to the journal prior to initiating the peer-review process. In this study we aimed to identify currently active overlay journals and examine their characteristics. We utilised an explorative web search and contacted key service providers for additional information. The final sample consisted of 34 overlay journals. While the results show that new overlay journals have been actively established within recent years, the current presence of overlay journals remains diminutive compared to the overall number of open access journals. Most overlay journals publish articles in natural sciences, mathematics or computer sciences, and are commonly published by groups of academics rather than formal organisations. They may also rank highly within the traditional journal citation metrics. None of the investigated journals required fees from authors, which is likely related to the cost-effective aspects of the overlay publishing model. Both the growth in adoption of open access preprint repositories and researcher

Many scholarly societies face challenges in adapting their publishing to an open access model where neither authors nor readers pay any fees. Some have argued that one of the main barriers is the actual cost of publishing. The goal of this paper is to show that the actual costs can be extremely low while still maintaining scholarly quality. We accomplish this by building a journal publishing workflow that minimizes the amount of required human labor. We recently built a software system for this and launched a journal using the system, and we estimate estimate our cost to publish this journal is approximately \$705 per year, plus \$1 per article and about 10 minutes of volunteer labor per article. We benefited from two factors, namely the fact that authors in our discipline use LaTeX to prepare their manuscripts, and we had volunteer labor to develop software and run the journal. We have made most of this software open source in the hopes that it can help others.

Defining and measuring internationality as a function of influence diffusion of scientific journals is an open problem. There exists no metric to rank journals based on the extent or scale of internationality. Measuring internationality is qualitative, vague, open to interpretation and is limited by vested interests. With the tremendous increase in the number of journals in various fields and the unflinching desire of academics across the globe to publish in "international" journals, it has become an absolute necessity to evaluate, rank and categorize journals based on internationality. Authors, in the current work have defined internationality as a measure of influence that transcends across geographic boundaries. There are concerns raised by the authors about unethical practices reflected in the process of journal publication whereby scholarly influence of a select few are artificially boosted, primarily by resorting to editorial maneuvres. To counter the impact of such tactics, authors have come up with a new method that defines and measures internationality by eliminating such local effects when computing the influence of journals. A new metric, Non-Local Influence Quotient(NLI

The preservation of the scholarly record has been a point of concern since the beginning of knowledge production. With print publications, the responsibility rested primarily with librarians, but the shift toward digital publishing and, in particular, the introduction of open access (OA) have caused ambiguity and complexity. Consequently, the long-term accessibility of journals is not always guaranteed, and they can even disappear from the web completely. The focus of this exploratory study is on the phenomenon of vanished journals, something that has not been carried out before. For the analysis, we consulted several major bibliographic indexes, such as Scopus, Ulrichsweb, and the Directory of Open Access Journals, and traced the journals through the Internet Archive's Wayback Machine. We found 174 OA journals that, through lack of comprehensive and open archives, vanished from the web between 2000 and 2019, spanning all major research disciplines and geographic regions of the world. Our results raise vital concern for the integrity of the scholarly record and highlight the urgency to take collaborative action to ensure continued access and prevent the loss of more scholarly knowl

Thrombosis under high-shear conditions is mediated by the mechanosensitive blood glycoprotein von Willebrand Factor (vWF). vWF unfolds in response to strong flow gradients and facilitates rapid recruitment of platelets in flowing blood. While the thrombogenic effect of vWF is well recognized, its conformational response in complex flows has largely been omitted from numerical models of thrombosis. We recently presented a continuum model for the unfolding of vWF, where we represented vWF transport and its flow-induced conformational change using convection-diffusion-reaction equations. Here, we incorporate the vWF component into our multi-constituent model of thrombosis, where the local concentration of stretched vWF amplifies the deposition rate of free-flowing platelets and reduces the shear cleaning of deposited platelets. We validate the model using three benchmarks: in vitro model of atherothrombosis, a stagnation point flow, and the PFA-100, a clinical blood test commonly used for screening for von Willebrand Disease (vWD). The simulations reproduced the key aspects of vWF-mediated thrombosis observed in these experiments, such as the thrombus location, thrombus growth dynamic

We compare the network of aggregated journal-journal citation relations provided by the Journal Citation Reports (JCR) 2012 of the Science and Social Science Citation Indexes (SCI and SSCI) with similar data based on Scopus 2012. First, global maps were developed for the two sets separately; sets of documents can then be compared using overlays to both maps. Using fuzzy-string matching and ISSN numbers, we were able to match 10,524 journal names between the two sets; that is, 96.4% of the 10,936 journals contained in JCR or 51.2% of the 20,554 journals covered by Scopus. Network analysis was then pursued on the set of journals shared between the two databases and the two sets of unique journals. Citations among the shared journals are more comprehensively covered in JCR than Scopus, so the network in JCR is denser and more connected than in Scopus. The ranking of shared journals in terms of indegree (that is, numbers of citing journals) or total citations is similar in both databases overall (Spearman's \r{ho} > 0.97), but some individual journals rank very differently. Journals that are unique to Scopus seem to be less important--they are citing shared journals rather than bein

Using the Scopus dataset (1996-2007) a grand matrix of aggregated journal-journal citations was constructed. This matrix can be compared in terms of the network structures with the matrix contained in the Journal Citation Reports (JCR) of the Institute of Scientific Information (ISI). Since the Scopus database contains a larger number of journals and covers also the humanities, one would expect richer maps. However, the matrix is in this case sparser than in the case of the ISI data. This is due to (i) the larger number of journals covered by Scopus and (ii) the historical record of citations older than ten years contained in the ISI database. When the data is highly structured, as in the case of large journals, the maps are comparable, although one may have to vary a threshold (because of the differences in densities). In the case of interdisciplinary journals and journals in the social sciences and humanities, the new database does not add a lot to what is possible with the ISI databases.

Hemostasis and thrombosis are often thought as two sides of the same clotting mechanism whereas hemostasis is a natural protective mechanism to prevent bleeding and thrombosis is a blood clot abnormally formulated inside a blood vessel, blocking the normal blood flow. The evidence to date suggests that at least arterial thrombosis results from the same critical pathways of hemostasis. Analysis of these complex processes and pathways using quantitative systems pharmacological model-based approach can facilitate the delineation of the causal pathways that lead to the emergence of thrombosis. In this paper, we provide an overview of the main molecular and physiological mechanisms associated with hemostasis and thrombosis, and review the models and quantitative system pharmacological modeling approaches that are relevant in characterizing the interplay among the multiple factors and pathways of thrombosis. An emphasis is given to computational models for drug development. Future trends are discussed.

Predatory journals are Open Access journals of highly questionable scientific quality. Such journals pretend to use peer review for quality assurance, and spam academics with requests for submissions, in order to collect author payments. In recent years predatory journals have received a lot of negative media. While much has been said about the harm that such journals cause to academic publishing in general, an overlooked aspect is how much articles in such journals are actually read and in particular cited, that is if they have any significant impact on the research in their fields. Other studies have already demonstrated that only some of the articles in predatory journals contain faulty and directly harmful results, while a lot of the articles present mediocre and poorly reported studies. We studied citation statistics over a five-year period in Google Scholar for 250 random articles published in such journals in 2014, and found an average of 2,6 citations per article and that 60 % of the articles had no citations at all. For comparison a random sample of articles published in the approximately 25,000 peer reviewed journals included in the Scopus index had an average of 18,1 cit

The study of thrombosis is crucial to understand and develop new therapies for diseases like deep vein thrombosis, diabetes related strokes, pulmonary embolism etc. The last two decades have seen an exponential growth in studies related to the blood clot formation using computational tools and through experiments. Despite of this growth, the complete mechanism behind thrombus formation and hemostasis is not known yet. The computational models and methods used in this context are diversified into different spatiotemporal scales, yet there is no single model which can predict both physiological and mechanical properties of the blood clots. In this review, we will attempt to list out all major strategies attempted by researchers so far to model the blood clot formation using existing computational techniques. This review classifies them into continuum level, system level, discrete particles and multi-scale methods. We will also discuss the strength and weakness of various methods and possible future directions in which the computational blood clot research can thrive.

This paper reviews research literature on Diamond Open Access (DOA) journals - sometimes also called Platinum Open Access - that was produced after this journal segment started to become a priority in European research policy around 2020. It contextualizes the current science policy debate, critically examines different understandings of DOA, and reviews studies on the role of such journals in scholarly communication. Most existing research consists of quantitative studies focusing on aspects such as the number of DOA journals, their publication output, the diversity of the landscape in terms of subject areas, languages, publishing entities, indexing in major databases, awareness and perception among scholars, cost analyses, as well as insights into the internal operations of DOA journals. The review shows that research on DOA journals is partly influenced by the science policy discourse in at least two ways: first, through the normativity inherent in that discourse, and second, through the temporality of policy-driven research of practical relevance, which leaves important aspects of the phenomenon understudied. Moreover, research on the DOA journal landscape has implications beyo

Using "Analyze Results" at the Web of Science, one can directly generate overlays onto global journal maps of science. The maps are based on the 10,000+ journals contained in the Journal Citation Reports (JCR) of the Science and Social Science Citation Indices (2011). The disciplinary diversity of the retrieval is measured in terms of Rao-Stirling's "quadratic entropy." Since this indicator of interdisciplinarity is normalized between zero and one, the interdisciplinarity can be compared among document sets and across years, cited or citing. The colors used for the overlays are based on Blondel et al.'s (2008) community-finding algorithms operating on the relations journals included in JCRs. The results can be exported from VOSViewer with different options such as proportional labels, heat maps, or cluster density maps. The maps can also be web-started and/or animated (e.g., using PowerPoint). The "citing" dimension of the aggregated journal-journal citation matrix was found to provide a more comprehensive description than the matrix based on the cited archive. The relations between local and global maps and their different functions in studying the sciences in terms of journal lit

This paper introduces the Unique Citing Documents Journal Impact Factor(Uniq-JIF) as a supplement to the traditional Journal Impact Factor(JIF). The Uniq-JIF counts each citing document only once, aiming to reduce the effects of citation manipulations. Analysis of 2023 Journal Citation Reports data shows that for most journals, the Uniq-JIF is less than 20% lower than the JIF, though some journals show a drop of over 75%. The Uniq-JIF also highlights significant reductions for journals suppressed due to citation issues, indicating its effectiveness in identifying problematic journals. The Uniq-JIF offers a more nuanced view of a journal's influence and can help reveal journals needing further scrutiny.

An exploratory, descriptive analysis is presented of the national orientation of scientific, scholarly journals as reflected in the affiliations of publishing or citing authors. It calculates for journals covered in Scopus an Index of National Orientation (INO), and analyses the distribution of INO values across disciplines and countries, and the correlation between INO values and journal impact factors. The study did not find solid evidence that journal impact factors are good measures of journal internationality in terms of the geographical distribution of publishing or citing authors, as the relationship between a journal's national orientation and its citation impact is found to be inverse U-shaped. In addition, journals publishing in English are not necessarily internationally oriented in terms of the affiliations of publishing or citing authors; in social sciences and humanities also USA has their nationally oriented literatures. The paper examines the extent to which nationally oriented journals entering Scopus in earlier years, have become in recent years more international. It is found that in the study set about 40 per cent of such journals does reveal traces of internati

The ongoing controversy surrounding transformative agreements, which aim to transition subscription-based journal publishing to full open access, highlights the need for large-scale studies assessing the impact of these agreements on hybrid open access. By combining multiple open data sources, including cOAlition S Journal Checker, Crossref, and OpenAlex, this study presents a novel approach that analyses over 700 agreements. Results suggest a strong growth in open access, from 4.3% in 2018 to 15% in 2022. Over five years, 11,189 hybrid journals provided open access to 742,369 out of 8,146,958 articles (9.1%). Authors who could make use of transformative agreements contributed 328,957 open access articles (44%) during this period, reaching a peak in 2022 with 143,615 out of 249,511 open access articles (58%). While this trend was predominantly driven by the three commercial publishers Elsevier, Springer Nature, and Wiley, open access uptake varied substantially across journals, publishers, disciplines, and countries. Particularly, the OECD and BRICS areas revealed different publication trends. In conclusion, this study suggests that current levels of implementation of transformativ

Thrombosis in rotary blood pumps arises from complex flow conditions that remain difficult to translate into reliable and interpretable risk predictions using existing computational models. This limitation reflects an incomplete understanding of how specific flow features contribute to thrombus initiation and growth. This study introduces an interpretable machine learning framework for spatial thrombosis assessment based directly on computational fluid dynamics-derived flow features. A logistic regression (LR) model combined with a structured feature-selection pipeline is used to derive a compact and physically interpretable feature set, including nonlinear feature combinations. The framework is trained using spatial risk patterns from a validated, macro-scale thrombosis model for two representative scenarios. The model reproduces the labeled risk distributions and identifies distinct sets of flow features associated with increased thrombosis risk. When applied to a centrifugal pump, despite training on a single axial pump operating point, the model predicts plausible thrombosis-prone regions. These results show that interpretable machine learning can link local flow features to th