Quaternary ammonium salt of oligomer-25 conidine (QAS O-25C) was used for regulation of hypocoagulation effect of Syncumar--anticoagulant of indirect type of action. The experiments were carried out on male rats. Experimental methods included thromboelastography, determination of thromboplastin time (after Quick) and determination of activity of single coagulation factors. It was shown that injection of QAS O-25C reliably do not affect blood coagulation. The combined action of QAS O-25C and Syncumar resulted in a twofold increase in the activity of factors IX and X within 24 h after the injection and in complete recovery after 48 h. After Syncumar injection per os we observed deep-hypercoagulation which was maintained even within 48 after the injection. The effect of QAS O-25C modulating the Syncular anticoagulant activity is probably connected with intensification of protein synthesis in the liver and, specifically, with an increase in the yield of active precursors of the factors of prothrombin complex.
A black hole observed during a dramatic 2023 eruption did not simply devour gas from its nearby companion star。 It also expelled large amounts of material through powerful jets and winds, even after the outburst had nearly faded。 The results suggest black holes may continue reshaping their surroundings long after their brightest fireworks end
Popular AI-powered food apps may make calorie counting easier, but they may also leave out a surprisingly large part of the meal。 Four apps underestimated calories and fat by about one-third when tested against carefully prepared meals。 High-fat ketogenic dishes appeared to cause the most trouble, while carbohydrates were measured more consistently
Rice University chemists have found a new way to make neodymium, a rare-earth metal, interact with oxygen。 Using a specially designed molecular structure described as a “basket,” the team positioned the atoms so they could form a bond once thought unlikely。 The breakthrough produced highly reactive compounds that could eventually give chemists alte
Dying Sun-like stars may not fade away quietly。 As blobs of gas erupt unevenly from their swollen surfaces, each burst gives the star a tiny push in the opposite direction。 Thousands of these random kicks could eventually break apart distant stellar pairs or, in rare cases, drive two stars into a violent collision
A new chemical process can transform three of the most common plastics into high-purity hydrogen without sorting them first。 The technique operates at much lower temperatures than traditional gasification and captures most of the plastic’s carbon in solid or liquid forms instead of releasing it as carbon dioxide
NASA is preparing for future astronaut landings on the Moon with an unusually ambitious orbital rehearsal。 During Artemis III in 2027, Orion astronauts will rendezvous and dock separately with prototype lunar landers from Blue Origin and SpaceX, allowing crews and ground teams to test the complex maneuvers needed for later missions
A newly discovered turning point in the Sun’s 11-year cycle could allow scientists to predict future solar activity years earlier than before。 At this “switch-off” point, the most violent space weather abruptly ends, and the remaining number of sunspots offers clues about the next cycle’s strength。 Early projections suggest Solar Cycle 26 may be mo
The hot new roguelite twin-stick shooter lives up to the hype
NASA astronaut Chris Williams and two Roscosmos cosmonauts are back on Earth after spending 241 days aboard the International Space Station。 Their journey covered more than 102 million miles and included 3,856 trips around the planet
A person’s sleeping brain may reveal warning signs of dementia long before memory problems begin。 Researchers used machine learning to analyze EEG recordings from about 7,000 adults and found that an older-than-expected “brain age” was tied to a sharply higher dementia risk。 Every additional 10 years of brain aging raised that risk by nearly 40%
Scientists traced a mysterious surge of low-energy gamma rays from zinc-70 to magnetic changes occurring inside its nucleus。 The breakthrough could improve models of how stars, supernovae, and neutron star mergers create heavy elements
Cosmic expansion allows distant galaxies to move away faster than light, while still letting us see ancient light they emitted when they were much closer。 Eventually, accelerating expansion will push nearly every galaxy beyond our Local Group out of sight, making the Universe appear almost empty