Quaternary ammonium salt of oligomer-25 conidine (QAS O-25C) was used for regulation of hypocoagulation effect of Syncumar--anticoagulant of indirect type of action. The experiments were carried out on male rats. Experimental methods included thromboelastography, determination of thromboplastin time (after Quick) and determination of activity of single coagulation factors. It was shown that injection of QAS O-25C reliably do not affect blood coagulation. The combined action of QAS O-25C and Syncumar resulted in a twofold increase in the activity of factors IX and X within 24 h after the injection and in complete recovery after 48 h. After Syncumar injection per os we observed deep-hypercoagulation which was maintained even within 48 after the injection. The effect of QAS O-25C modulating the Syncular anticoagulant activity is probably connected with intensification of protein synthesis in the liver and, specifically, with an increase in the yield of active precursors of the factors of prothrombin complex.
A new chemical process can transform three of the most common plastics into high-purity hydrogen without sorting them first。 The technique operates at much lower temperatures than traditional gasification and captures most of the plastic’s carbon in solid or liquid forms instead of releasing it as carbon dioxide
A new analysis suggests the Sun holds far more silver than earlier estimates indicated。 More advanced models of the solar atmosphere raised the calculated amount by 55 percent, bringing it into much closer agreement with ancient meteorites。 The technique may also help scientists track the cosmic origins of silver and other heavy elements
Popular AI-powered food apps may make calorie counting easier, but they may also leave out a surprisingly large part of the meal。 Four apps underestimated calories and fat by about one-third when tested against carefully prepared meals。 High-fat ketogenic dishes appeared to cause the most trouble, while carbohydrates were measured more consistently
Scientists have uncovered new evidence that Venus may still be tearing itself apart from within。 Advanced 3D simulations indicate that some of the planet's giant rift valleys formed relatively recently and could still be expanding。 The results suggest Venus has a far more active interior than researchers once believed, challenging the long-held vie
The hot new roguelite twin-stick shooter lives up to the hype
Some group with no modern descendants contributed a lot to our genomes
A black hole observed during a dramatic 2023 eruption did not simply devour gas from its nearby companion star。 It also expelled large amounts of material through powerful jets and winds, even after the outburst had nearly faded。 The results suggest black holes may continue reshaping their surroundings long after their brightest fireworks end
Scientists traced a mysterious surge of low-energy gamma rays from zinc-70 to magnetic changes occurring inside its nucleus。 The breakthrough could improve models of how stars, supernovae, and neutron star mergers create heavy elements
A newly discovered turning point in the Sun’s 11-year cycle could allow scientists to predict future solar activity years earlier than before。 At this “switch-off” point, the most violent space weather abruptly ends, and the remaining number of sunspots offers clues about the next cycle’s strength。 Early projections suggest Solar Cycle 26 may be mo
Astronomers have found the first confirmed atmosphere around a rocky planet in another star’s habitable zone。 The planet, LHS 1140 b, revealed its atmosphere through helium slowly leaking into space。 Located 48 light-years away, the world may have preserved its atmosphere for billions of years, making it a promising target in the search for potenti
Scientists have created twisted laser beams that interact differently with right-handed and left-handed molecules, revealing their identity through the fragments they produce。 The approach could provide a faster, simpler, and more sensitive way to analyze important molecules used in chemistry and pharmaceuticals
A surprisingly simple change could make sodium-ion batteries far more powerful while opening the door to turning seawater into drinking water。 Researchers at the University of Surrey found that sodium vanadium oxide performs much better when its naturally occurring water is left inside instead of being removed during manufacturing
NASA astronaut Chris Williams and two Roscosmos cosmonauts are back on Earth after spending 241 days aboard the International Space Station。 Their journey covered more than 102 million miles and included 3,856 trips around the planet