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The surging demand for artificial intelligence (AI) has led to a rapid expansion of energy-intensive data centers, contributing to criteria air pollutant emissions and raising public health concerns that have received comparatively limited attention in sustainability assessments. This paper introduces a principled methodology to model air pollutant emissions for data centers and estimate the public health impacts. Our findings reveal that the growing demand for AI and computing technologies is projected to push the total annual public health burden of U.S. data centers up to more than $20 billion in 2028. Although national-level impacts remain modest, data center health costs are unevenly distributed: in the most affected counties, the estimated per-household health burden can reach about seven times the national average. Next, we propose a health-informed computing framework that explicitly incorporates public health impacts into data center resource management across space and time, mitigating public health costs while supporting environmental sustainability. More broadly, we recommend extended energy reporting to include public health impact of data centers and paying attention

Rapidly evolving technology, data and analytic landscapes are permeating many fields and professions. In public health, the need for data science skills including data literacy is particularly prominent given both the potential of novel data types and analysis methods to fill gaps in existing public health research and intervention practices, as well as the potential of such data or methods to perpetuate or augment health disparities. Through a review of public health courses and programs at the top 10 U.S. and globally ranked schools of public health, this article summarizes existing educational efforts in public health data science. These existing practices serve to inform efforts for broadening such curricula to further schools and populations. Data science ethics course offerings are also examined in context of assessing how population health principles can be blended into training across levels of data involvement to augment the traditional core of public health curricula. Parallel findings from domestic and international 'outside the classroom' training programs are also synthesized to advance approaches for increasing diversity in public health data science. Based on these p

A recent rise in online content expressing concerns with public health initiatives has contributed to already stalled uptake of preemptive measures globally. Future public health efforts must attempt to understand such content, what concerns it may raise among readers, and how to effectively respond to it. To this end, we present ConcernScope, a platform that uses a teacher-student framework for knowledge transfer between large language models and light-weight classifiers to quickly and effectively identify the health concerns raised in a text corpus. The platform allows uploading massive files directly, automatically scraping specific URLs, and direct text editing. ConcernScope is built on top of a taxonomy of public health concerns. Intended for public health officials, we demonstrate several applications of this platform: guided data exploration to find useful examples of common concerns found in online community datasets, identification of trends in concerns through an example time series analysis of 186,000 samples, and finding trends in topic frequency before and after significant events.

We present a technical case study on the Privacy-Enhancing Technologies (PETs) for Public Health Challenge, a collaborative effort to safely leverage sensitive private sector data for social impact, specifically pandemic management. The project utilized Differential Privacy (DP) to create realistic, privacy-preserved synthetic financial transaction data, which was then combined with public health and mobility datasets. This approach successfully addressed the critical hurdle of sharing sensitive financial information for research and policy. The analysis demonstrated that this synthetic, DP-protected data possesses significant spatial-temporal and predictive power for public health. Key outcomes include the development of six reusable tools and frameworks supporting diagnostic nowcasting (e.g., Hotspot Detection, Pandemic Adherence Monitoring) and predictive forecasting (e.g., Mobility Analysis, Contact Matrix Estimation) for epidemiological decision-making. The study provides best practices for advancing data sharing in a privacy-compliant manner.

Global public health surveillance relies on reporting structures and transmission of trustworthy health reports. But in practice, these processes may not always be fast enough, or are hindered by procedural, technical, or political barriers. GPHIN, the Global Public Health Intelligence Network, was designed in the late 1990s to scour mainstream news for health events, as that travels faster and more freely. This paper outlines the next generation of GPHIN, which went live in 2017, and reports on design decisions underpinning its new functions and innovations.

This paper presents a holistic systems informatics approach, i.e., Define, Measure, Analyze, Improve, and Control (DMAIC), for epidemic response and management through the intensive use of data, statistics and optimization. Despite the sustained successes of system informatics in a variety of established industries such as manufacturing, logistics, services and beyond, there is a dearth of concentrated review and application of the data-driven DMAIC approach in the context of epidemic outbreaks. First, we define specific challenges posed by epidemic outbreaks to populational health, health systems, as well as economic challenges to different industries such as retailing, education and manufacturing. Second, we present a review of medical testing and statistical sampling methods for data collection, as well as existing efforts in data management and data visualization. Third, we discuss the importance to realizing the full potential of data for epidemic insights, and emphasize the need to leverage analytical methods and tools for decision support. Fourth, an epidemic brings imperative changes to health systems. We discuss the new trend of healthcare solutions to improve system resil

Time elapsed till an event of interest is often modeled using the survival analysis methodology, which estimates a survival score based on the input features. There is a resurgence of interest in developing more accurate prediction models for time-to-event prediction in personalized healthcare using modern tools such as neural networks. Higher quality features and more frequent observations improve the predictions for a patient, however, the impact of including a patient's geographic location-based public health statistics on individual predictions has not been studied. This paper proposes a complementary improvement to survival analysis models by incorporating public health statistics in the input features. We show that including geographic location-based public health information results in a statistically significant improvement in the concordance index evaluated on the Surveillance, Epidemiology, and End Results (SEER) dataset containing nationwide cancer incidence data. The improvement holds for both the standard Cox proportional hazards model and the state-of-the-art Deep Survival Machines model. Our results indicate the utility of geographic location-based public health feat

For a long time, public health events, such as disease incidence or vaccination activity, have been monitored to keep track of the health status of the population, allowing to evaluate the effect of public health initiatives and to decide where resources for improving public health are best spent. This thesis investigates the use of web data mining for public health monitoring, and makes contributions in the following two areas: New approaches for predicting public health events from web mined data, and novel applications of web mined data for public health monitoring.

Global rates of mental health concerns are rising, and there is increasing realization that existing models of mental health care will not adequately expand to meet the demand. With the emergence of large language models (LLMs) has come great optimism regarding their promise to create novel, large-scale solutions to support mental health. Despite their nascence, LLMs have already been applied to mental health related tasks. In this paper, we summarize the extant literature on efforts to use LLMs to provide mental health education, assessment, and intervention and highlight key opportunities for positive impact in each area. We then highlight risks associated with LLMs' application to mental health and encourage the adoption of strategies to mitigate these risks. The urgent need for mental health support must be balanced with responsible development, testing, and deployment of mental health LLMs. It is especially critical to ensure that mental health LLMs are fine-tuned for mental health, enhance mental health equity, and adhere to ethical standards and that people, including those with lived experience with mental health concerns, are involved in all stages from development through

Large Language Models (LLMs) hold promise in addressing complex medical problems. However, while most prior studies focus on improving accuracy and reasoning abilities, a significant bottleneck in developing effective healthcare agents lies in the readability of LLM-generated responses, specifically, their ability to answer public health problems clearly and simply to people without medical backgrounds. In this work, we introduce RephQA, a benchmark for evaluating the readability of LLMs in public health question answering (QA). It contains 533 expert-reviewed QA pairs from 27 sources across 13 topics, and includes a proxy multiple-choice task to assess informativeness, along with two readability metrics: Flesch-Kincaid grade level and professional score. Evaluation of 25 LLMs reveals that most fail to meet readability standards, highlighting a gap between reasoning and effective communication. To address this, we explore four readability-enhancing strategies-standard prompting, chain-of-thought prompting, Group Relative Policy Optimization (GRPO), and a token-adapted variant. Token-adapted GRPO achieves the best results, advancing the development of more practical and user-friendl

The COVID-19 pandemic has highlighted the dire necessity to improve public health literacy for societal resilience. YouTube, the largest video-sharing social media platform, provides a vast repository of user-generated health information in a multi-media-rich format which may be easier for the public to understand and use if major concerns about content quality and accuracy are addressed. This study develops an automated solution to identify, retrieve and shortlist medically relevant and understandable YouTube videos that domain experts can subsequently review and recommend for disseminating and educating the public on the COVID-19 pandemic and similar public health outbreaks. Our approach leverages domain knowledge from human experts and machine learning and natural language processing methods to provide a scalable, replicable, and generalizable approach that can also be applied to enhance the management of many health conditions.

Mobile health has the potential to revolutionize health care delivery and patient engagement. In this work, we discuss how integrating Artificial Intelligence into digital health applications-focused on supply chain, patient management, and capacity building, among other use cases-can improve the health system and public health performance. We present an Artificial Intelligence and Reinforcement Learning platform that allows the delivery of adaptive interventions whose impact can be optimized through experimentation and real-time monitoring. The system can integrate multiple data sources and digital health applications. The flexibility of this platform to connect to various mobile health applications and digital devices and send personalized recommendations based on past data and predictions can significantly improve the impact of digital tools on health system outcomes. The potential for resource-poor settings, where the impact of this approach on health outcomes could be more decisive, is discussed specifically. This framework is, however, similarly applicable to improving efficiency in health systems where scarcity is not an issue.

YouTube has rapidly emerged as a predominant platform for content consumption, effectively displacing conventional media such as television and news outlets. A part of the enormous video stream uploaded to this platform includes health-related content, both from official public health organizations, and from any individual or group that can make an account. The quality of information available on YouTube is a critical point of public health safety, especially when concerning major interventions, such as vaccination. This study differentiates itself from previous efforts of auditing YouTube videos on this topic by conducting a systematic daily collection of posted videos mentioning vaccination for the duration of 3 months. We show that the competition for the public's attention is between public health messaging by institutions and individual educators on one side, and commentators on society and politics on the other, the latest contributing the most to the videos expressing stances against vaccination. Videos opposing vaccination are more likely to mention politicians and publication media such as podcasts, reports, and news analysis, on the other hand, videos in favor are more li

Malaria can be prevented, diagnosed, and treated; however, every year, there are more than 200 million cases and 200.000 preventable deaths. Malaria remains a pressing public health concern in low- and middle-income countries, especially in sub-Saharan Africa. We describe how by means of mobile health applications, machine-learning-based adaptive interventions can strengthen malaria surveillance and treatment adherence, increase testing, measure provider skills and quality of care, improve public health by supporting front-line workers and patients (e.g., by capacity building and encouraging behavioral changes, like using bed nets), reduce test stockouts in pharmacies and clinics and informing public health for policy intervention.

In a recent series of high impact public health publications, the c-index was used as measure of prediction to assess the public health relevance of a risk factor. I demonstrate that the c-index is an inferior measure as compared to the classical epidemiologic measures most commonly employed for risk prediction and public health assessment such as disease incidence, relative risk (RR) and population-attributable risk (PAR). I recommend using the latter measures when assessing the public health relevance of a risk factor.

The debate surrounding the provision of welfare by state institutions has been widely discussed in the field of political economics since the 1930s. Related research also focuses on welfare supply at an international system level. This article assesses whether international cooperation in the area of sharing remote sensing data leads to the supply of global public goods, which to date has not yet been discussed in related scholarly literature. The supply of global public goods is assessed within the GEO international regime and leads to the use of the non-rivalrous GEOSS, which can be accessed by every socio-economic group in every UN member country including future generations. However, providing the benefit of GEOSS is not always favourable because of the low number of financially participating consumers.

Selecting the right monitoring level in Remote Patient Monitoring (RPM) systems for e-healthcare is crucial for balancing patient outcomes, various resources, and patient's quality of life. A prior work has used one-dimensional health representations, but patient health is inherently multidimensional and typically consists of many measurable physiological factors. In this paper, we introduce a multidimensional health state model within the RPM framework and use dynamic programming to study optimal monitoring strategies. Our analysis reveals that the optimal control is characterized by switching curves (for two-dimensional health states) or switching hyper-surfaces (in general): patients switch to intensive monitoring when health measurements cross a specific multidimensional surface. We further study how the optimal switching curve varies for different medical conditions and model parameters. This finding of the optimal control structure provides actionable insights for clinicians and aids in resource planning. The tunable modeling framework enhances the applicability and effectiveness of RPM services across various medical conditions.

Electronic Health Record (EHR) has become an essential tool in the healthcare ecosystem, providing authorized clinicians with patients' health-related information for better treatment. While most developed countries are taking advantage of EHRs to improve their healthcare system, it remains challenging in developing countries to support clinical decision-making and public health using a computerized patient healthcare information system. This paper proposes a novel EHR architecture suitable for developing countries--an architecture that fosters inclusion and provides solutions tailored to all social classes and socioeconomic statuses. Our architecture foresees an internet-free (offline) solution to allow medical transactions between healthcare organizations, and the storage of EHRs in geographically underserved and rural areas. Moreover, we discuss how artificial intelligence can leverage anonymous health-related information to enable better public health policy and surveillance.

The rapid spread of health misinformation on online social networks (OSNs) during global crises such as the COVID-19 pandemic poses challenges to public health, social stability, and institutional trust. Centrality metrics have long been pivotal in understanding the dynamics of information flow, particularly in the context of health misinformation. However, the increasing complexity and dynamism of online networks, especially during crises, highlight the limitations of these traditional approaches. This study introduces and compares three novel centrality metrics: dynamic influence centrality (DIC), health misinformation vulnerability centrality (MVC), and propagation centrality (PC). These metrics incorporate temporal dynamics, susceptibility, and multilayered network interactions. Using the FibVID dataset, we compared traditional and novel metrics to identify influential nodes, propagation pathways, and misinformation influencers. Traditional metrics identified 29 influential nodes, while the new metrics uncovered 24 unique nodes, resulting in 42 combined nodes, an increase of 44.83%. Baseline interventions reduced health misinformation by 50%, while incorporating the new metrics