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A total of 102 patients were examined, 32 of these with true eczema, 38 with exudative mycosis of the soles, and 32 with eczema etiologically related to a fungal infection. Analysis of the immune and biochemical reactions in the examinees has shown a marked reduction of adenyl nucleotides in the leukocytic suspension and neutrophils of patients with a mycotic infection as against those with true eczema. The lowest creatine phosphate levels were detected in the leukocytic suspension and neutrophils of the patients suffering from eczema etiologically related to mycosis and exudative mycosis of the soles. These results give grounds to search for effective corrective therapy.

Histologic and cytologic parallels in 9 cases with malignant schwannomas were correlated to findings in preparations of verified fibrosarcomas and muscular sarcomas, characterized by a similar cytomorphologic picture, in order to define the cytologic differential diagnostic criteria of nerve tissue malignant tumors. Preoperative and suboperative specimens were under study. Analysis of the results evidences that in the majority of cases malignant schwannoma cytogram can be correctly verified if the level of tumor cell differentiation and the respective cytomorphologic shifts be taken into consideration, this being of paramount importance both for the choice of the treatment strategy and for the prognosis.

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Automated fluorescent microscope developed by the authors permits photometry of microquantities of cellular suspensions in scanning standard 60-well plates with a flat bottom. Automated and semiautomated modes of operation are possible. Fluorescent stains and schemes of staining the examined cells that yield stable results in the lymphocytotoxic test have been selected. Comparative analysis of the efficacies of histocompatibility antigens detection by the routine and the fluorescent technique has shown a number of advantages of the fluorescent method. Specific features of fluorescent stains used for staining live cells are described.

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The immunoturbidimetric micromethod for measuring the blood serum IgG has been adapted to the FP-900 analytic system. Monospecific sera to IgG (H) manufactured by several institutions in this country were used in the study. The volumes of antiserum solvents were selected and the analytical reliability of the suggested micromethod assessed. Programs for introduction of the parameters for IgG measurements with FP-900 analyzer are presented.

The technique of making paper disks with Klebsiella bacteriocins is described, as is the method for improving the stability of bacteriocin preparations. The authors have developed a method for bacterial bacteriocin typing, facilitating the work and taking but 4-5 hrs. The results of klebocin typing of Klebsiella-237 strains with the use of the developed technique are presented.

Significant differences in the intensities of H2O2-induced biochemiluminescence of venous and capillary blood sera were revealed, as was a direct relationship between this parameter and hemoglobin level in the samples; this permits a conclusion on the improper employment of H2O2-induced biochemiluminescence of blood serum in diagnostic studies.

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Estimation of the degree of leukocyte migration inhibition in the oral cavity, following exposure to allergen solution, is a test widely used to assess a subject's allergy to drugs. To simplify this test and make it more effective, the authors suggest placing the samples in plate wells and drying them there; optically transparent polystyrene plates for enzyme immunoassay are employed. Effective adsorption of the cells on the carrier and the possibility of analyzing the samples with the help of multiple magnification permit a reliable detection of the migration inhibition. The method was tried in examinations of workers engaged in the manufacture of an x-ray contrast agent triambrin. Reduced migration levels were detected in 8 of the 12 examinees.

A tampon made of the new spongy polyvinyl-formal AQUIPOR 3500/40 is suggested for quantitative studies of mixed anaerobic-aerobic microflora. Comparison of the adsorption characteristics, the preservation of the tested pathologic material during the collection and transportation of the material, and the potential antibacterial characteristics of the suggested tampon and the traditional cotton wool tampons has shown the advantages of the new tampon, that permits standardization of the investigation by the quantitative bacteriologic method and preserves both aerobic and anaerobic microorganisms viable. This tampon may be used in studies of purulent wound and periodontal pocket microflora.

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Blood coagulation, immunobiochemical, and clinical characteristics were studied in patients with rheumatic fever running a protracted course treated by combined therapy including nerobol. To assess the therapeutic efficacy of nerobol, the patients were divided into 2 groups: Group 1 (30 patients) were administered combined antirheumatic therapy, Group 2 (30 patients) were administered the same + nerobol in a daily dose of 15 mg for 3-4 weeks. The findings evidence a positive effect of the drug on the status of patients in whom rheumatic fever runs a protracted course: blood procoagulative activity is reduced and anticoagulative activity elevated, blood immunobiochemical and clinical characteristics normalized.

A method for serial measurements of blood serum acid DNAse (3.1.4.5) and acid RNAse (3.1.4.23). The authors recommend measurements of acid nucleases at clinical biochemistry laboratories and use of these parameters for the prediction of outcomes of balneotherapy and other treatment modalities.

Analysis of the bacterial spectrum of 25 children with periodontitis has revealed that obligate anaerobes make up 65% of the bacteria. In 96% of cases anaerobic microorganisms are isolated in associations. Bacterial associations are analyzed.