Granzyme B (GraB) induces apoptosis in the presence of perforin. Perforin polymerizes in the cell membrane to form a nonspecific ion pore, but it is not known where GraB acts to initiate the events that ultimately lead to apoptosis. It has been hypothesized that GraB enters the target cell through a perforin channel and then initiates apoptosis by cleaving and activating members of the ICE/Ced-3 family of cell death proteases. To determine if GraB can enter the cell, we treated YAC-1 or HeLa cells with FITC-labeled GraB and measured intracellular fluorescence with a high sensitivity CCD camera and image analyzer. GraB was internalized and found diffusely dispersed in the cell cytoplasm within 10 min. Uptake was inhibited at low temperature (4 degrees C) and by pretreatment with metabolic inhibitors, NaF and DNP, or cytochalasin B, a drug that both blocks microfilament formation, and FITC-GraB remained on the cell membrane localized in patches. With the simultaneous addition of perforin and FITC-GraB, no significant increase in cytoplasmic fluorescence was observed over that found in cells treated only with FITC-GraB. However, FITC-GraB was now detected in the nucleus of apoptotic cells labeling apoptotic bodies and localized areas within and along the nuclear membrane. The ability of GraB to enter cells in the absence of perforin was reexamined using anti-GraB antibody immunogold staining of ultrathin cryosections of cells incubated with GraB. Within 15 min, gold particles were detected both on the plasma membrane and in the cytoplasm of cells with some gold staining adjacent to the nuclear envelope but not in the nucleus. Cells internalizing GraB in the absence of perforin appeared morphologically normal by Hoechst staining and electron microscopy. GraB directly microinjected into the cytoplasm of B16 melanoma cells induced transient plasma membrane blebbing and nuclear coarsening but the cells did not become frankly apoptotic unless perforin was added. We conclude that GraB can enter cells autonomously but that perforin initiates the apoptotic process and the entry of GraB into the nucleus.
Discussions of land grabs for various purposes, including environmental ends, have expanded in recent years, yet land grabbing remains inconsistently defined and poorly understood. Our ability to assess the extent to which land grabs are occurring, and to identify the mixture of factors driving land and resource acquisition, is limited. This paper assesses whether a land grab for conservation is happening in southern Chile, and identifies the various driving forces that combine to drive land acquisitions in the region, based on a detailed exploration of the recent massive growth in privately owned protected areas in the region. This paper finds that the various dominant definitions of land grabs each apply only partially to southern Chile, that land grabs for conservation need to be understood as the latest stage in a longer process by which the region's natural resources are incorporated into the Chilean and the global economy, and that green grabs interact in various ways with broader resource grabs, particularly for forestry and hydroelectricity. This case study demonstrates the limitations of some definitions of land grabs, particularly their focus on capitalist accumulation within land grabs, their international nature and their emphasis on legal processes.
The unprecedented increase in the world population coupled with the great demand for food have encouraged several investors to acquire land and water in some developing countries, Sudan is not an exception. This current phenomenon often referred to as “land grabbing” as it always violates the right of local land users and affects the environment. This paper aims to highlight the process by which local and foreign investors acquire communal lands in Sudan and to underline its implication on pastoral livelihood. The paper is mainly based on desk review and deep analysis of some recent documents. The paper has come out with the fact that under the pretext of development and food security, huge communal lands were taken from local producers and leased “soled” to the investors (grabbers). To facilitate land grabbing, the government of Sudan has frequently been embarked on amending land tenure system several times. The Unregistered Land Act of 1971, Ministerial Act of 1996 and the Investment Act of 2013, have paved the way for more land grabbing in Sudan. These acts ignored completely the historical right of the local communities over land resources. Lacks of transparency, unfair compensation and limited or absent consultation of the local communities are some characteristics shaping land grabbing in Sudan. Land for local producers is the main asset and a source of everything (livelihood) thus, denying such right means lacking everything. This explains why food insecurity, spread of poverty, disputes and conflict are now widely dominated most of pastoral areas. The paper aims to contribute to the ongoing debate on land grabbing and open windows for more research in such hot issue. It provides planners with some ideas that might help in formulating sound policy regarding land acquisition. Like any African country, the government of Sudan has to find rational way to make the investment a win win deal if it is really looking for food security, social peace and sustainable development.
Societal pressure on the global land and freshwater resources is increasing as a result of the rising food demand by the growing human population, dietary changes, and the enhancement of biofuel production induced by the rising oil prices and recent changes in United States and European Union bioethanol policies. Many countries and corporations have started to acquire relatively inexpensive and productive agricultural land located in foreign countries, as evidenced by the dramatic increase in the number of transnational land deals between 2005 and 2009. Often known as "land grabbing," this phenomenon is associated with an appropriation of freshwater resources that has never been assessed before. Here we gather land-grabbing data from multiple sources and use a hydrological model to determine the associated rates of freshwater grabbing. We find that land and water grabbing are occurring at alarming rates in all continents except Antarctica. The per capita volume of grabbed water often exceeds the water requirements for a balanced diet and would be sufficient to improve food security and abate malnourishment in the grabbed countries. It is found that about 0.31 × 10(12) m(3) · y(-1) of green water (i.e., rainwater) and up to 0.14 × 10(12) m(3) · y(-1) of blue water (i.e., irrigation water) are appropriated globally for crop and livestock production in 47 × 10(6) ha of grabbed land worldwide (i.e., in 90% of the reported global grabbed land).
Recent large-scale land acquisitions for agricultural production (including biofuels), popularly known as 'land grabbing', have attracted headline attention. Water as both a target and driver of this phenomenon has been largely ignored despite the interconnectedness of water and land. This special issue aims to fill this gap and to widen and deepen the lens beyond the confines of the literature’s still limited focus on agriculture-driven resource grabbing. The articles in this collection demonstrate that the fluid nature of water and its hydrologic complexity often obscure how water grabbing takes place and what the associated impacts on the environment and diverse social groups are. The fluid properties of water interact with the 'slippery' nature of the grabbing processes: unequal power relations; fuzziness between legality and illegality and formal and informal rights; unclear administrative boundaries and jurisdictions, and fragmented negotiation processes. All these factors combined with the powerful material, discursive and symbolic characteristics of water make 'water grabbing' a site for conflict with potential drastic impacts on the current and future uses and benefits of water, rights as well as changes in tenure relations.
Land grabbing has emerged as a significant issue in contemporary global governance that cuts across the fields of development, investment, food security, among others. Whereas land grabbing per se is not a new phenomenon, having historical precedents in the eras of imperialism, the character, scale, pace, orientation and key drivers of the recent wave of land grabs is a distinct historical phenomenon closely tied to major shifts in power and production in the global political economy. Land grabbing is facilitated by ever greater flows of capital, goods, and ideas across borders, and these flows occur through axes of power that are far more polycentric than the North-South imperialist tradition. In this introduction we argue that land grabbing speaks to many of the core questions of globalization studies. However, we note scholars of globalization have yet to deeply engage with this new field. We situate land grabbing in an era of advanced capitalism, multiple global crises and the role of new configurations of power and resistance in global governance institutions. The essays in this collection contribute to identifying land grabbing as an important and urgent topic for theoretical and empirical investigations to deepen our understanding of contemporary globalization and governance.
In many countries, public sector institutions impose heavy burdens on economic life: heavy and arbitrary taxes retard investment, regulations enrich corrupt bureaucrats, state firms consume national wealth, and the most talented people turn to rent-seeking rather than productive activities. As a consequence of such predatory policies--described in this book as the grabbing hand of the state--entrepreneurship lingers and economies stagnate. The authors of this collection of essays describe many of these pathologies of a grabbing hand government, and examine their consequences for growth. The essays share a common viewpoint that political control of economic life is central to the many government failures that we observe. Fortunately, a correct diagnosis suggests the cures, including the best strategies of fighting corruption, privatization of state firms, and institutional building in the former socialist economies. Depoliticization of economic life emerges as the crucial theme of the appropriate reforms. The book describes the experiences with the grabbing hand government and its reform in medieval Europe, developing countries, transition economies, as well as today's United States.
‘Land grab’ has become a catch‐all phrase to refer to the current explosion of (trans)national commercial land transactions mainly revolving around the production and export of food, animal feed, biofuels, timber and minerals. Two key dimensions of the current land grab – namely, the politics of changes in land use and property relations change (and the links between them) – are not sufficiently explored in the current literature. We attempt to address this gap by offering a preliminary analysis through an analytical approach that suggests some typologies as a step towards a fuller and better understanding of the politics of global land grabbing.
Rural populations around the world rely on small-scale farming and other uses of land and natural resources, which are often governed by customary, traditional, and indigenous systems of common property. In recent years, large-scale land acquisitions have drastically expanded; it is unclear whether the commons are a preferential target of these acquisitions. Here we argue that the contemporary global “land rush” could be happening at the expense of common-property systems around the world. While there is evidence that common-property systems have developed traditional institutions of resource governance that make them robust with respect to endogenous forces (e.g., uses by community members), it is less clear how vulnerable these arrangements are to exogenous drivers of globalization and expansion of transnational land investments. In common-property systems, farmers and local users may be unable to defend their customary rights and successfully compete with external actors. We define the notion of “commons grabbing” and report on an exploratory study that applied meta-analytical methods, drawing from the recent literature on large-scale land acquisitions and land grabbing. Informed by political economy and political ecology approaches, we coded selected cases on the basis of acquisition mechanisms, claims and property rights, changes in production system, and coercive dynamics, and explored the interactions between the different variables using association tests and qualitative comparative analysis. We found that the majority of the cases included in this analysis (44 of 56) could be examples of commons grabbing.
The term “ocean grabbing” has been used to describe actions, policies or initiatives that deprive small-scale fishers of resources, dispossess vulnerable populations of coastal lands, and/or undermine historical access to areas of the sea. Rights and access to marine resources and spaces are frequently reallocated through government or private sector initiatives to achieve conservation, management or development objectives with a variety of outcomes for different sectors of society. This paper provides a definition and gives examples of reallocations of marine resources or spaces that might constitute “ocean grabbing”. It offers a tentative framework for evaluating whether marine conservation, management or development is ocean grabbing and proposes an agenda for future research. For a reallocation to be considered ocean grabbing, it must: (1) occur by means of inadequate governance, and (2) be implemented using actions that undermine human security and livelihoods, or (3) produce impacts that reduce social–ecological well-being. Future research on ocean grabbing will: document case studies, drivers and consequences; conduct spatial and historical analyses; and investigate solutions. The intent is to stimulate rigorous discussion and promote systematic inquiry into the phenomenon of ocean grabbing.
We introduce this special issue by explaining seven characteristics of land grabbing in Latin America. These features are not unique to the region. By highlighting them – arguing, for instance, that a key aspect in Latin America is intra-regional land grabbing driven by (trans)Latina companies – we hope to inspire new cross-regional comparisons to understand the dynamics of “global” land grabbing. Our focus on Latin America challenges some problematic generalisations in the literature, for instance, that land grabs occur mainly in fragile states. We interrogate the relationship between land grabbing and the “foreignisation” narrative, and the need to revisit the broader question of land concentration. Thus we build upon the literature locating land grabs and the land question within the political economy of global capitalism. Cette introduction au numéro spécial présente sept caractéristiques de l'accaparement des terres en Amérique latine, caractéristiques qui ne sont pas propres à la région. En les mettant en lumière, notamment en soutenant qu'en Amérique latine le phénomène, impulsé par des compagnies latino-américaine, est avant tout intra-régional, nous espérons susciter de nouvelles comparaisons inter-régionales afin de mieux comprendre les dynamiques mondiales de l'accaparement de terres. L'accent mis sur Amérique latine permet de remettre en question des généralisations auxquelles s'adonnent de nombreux écrits, comme par exemple que l'accaparement se produit principalement dans les états fragiles. Nous examinons les liens établis entre l'accaparement de terres et la main mise étrangère pour montrer la nécessité de réévaluer la question élargie de la concentration de terres. Les articles du numéro situent l'accaparement des terres dans le cadre de l’économie politique du capitalisme mondial.
The contestation and appropriation of water is not new, but it has been highlighted by recent global debates on land grabbing. Water grabbing takes place in a field that is locally and globally plural-legal. Formal law has been fostering both land and water grabs but formal water and land management have been separated from each other—an institutional void that makes encroachment even easier. Ambiguous processes of global water and land governance have increased local-level uncertainties and complexities that powerful players can navigate, making them into mechanisms of exclusion of poor and marginalised people. As in formal land management corporate influence has grown. For less powerful players resolving ambiguities in conflicting regulatory frameworks may require tipping the balance towards the most congenial. Yet, compared with land governance, global water governance is less contested from an equity and water justice perspective, even though land is fixed, while water is fluid and part of the hydrological cycle; therefore water grabbing potentially affects greater numbers of diverse water users. Water grabbing can be a powerful entry point for the contestation needed to build counterweights to the neoliberal, corporate business-led convergence in global resource governance discourses and processes. Elaborating a human right to water in response to water grabbing is urgently needed.
This paper aims to redress the under-appreciated significance of rent for political ecological analysis. We introduce the notion of value grabbing, defined as the appropriation of (surplus) value through rent. A concept that is analytically distinct from accumulation, rent is both a social relation and a distributional process that is increasingly central to the reproduction of contemporary capitalism. Emphasis is placed on the “grabbing” of value in order to shed light on the processes at work by which surplus value is distributed unevenly between different classes and fractions of classes. A focus on rent within political ecology, we argue, can help us distinguish between two organically related but analytically distinct “moments”: (a) the creation of property rights that establish rent relations and (b) the struggle over the appropriation and distribution of surplus value generated by the rent relation itself. We explore some of the implications of this perspective for understanding new forms of socio-ecological struggles and their varied relations to the state. We maintain that a value-grabbing perspective has far-reaching consequences for political ecology, as it provides a sharp conceptual tool for situating a wide range of socio-ecological conflicts and movements as class struggles over value appropriation and distribution.
‘Green grabs,’ or the expropriation of land or resources for environmental purposes, constitute an important component of the current global land grab explosion. We argue that international environmental institutions are increasingly cultivating the terrain for green grabbing. As sites that circulate and sanction forms of knowledge, establish regulatory devices and programmatic targets, and align and articulate actors with these mechanisms, they structure emergent green market opportunities and practices. Drawing on the idea of primitive accumulation as a continual process, we examine the 10th Conference of the Parties to the United Nations Convention on Biological Diversity as one such institution.
Developments in the area of ‘precision agriculture’ are creating new data points (about flows, soils, pests, climate) that agricultural technology providers ‘grab’, aggregate, compute and/or sell. Food producers now churn out food and, increasingly, data. ‘Land grabs’ on the horizon in the global south are bound up with the dynamics of data grabbing, although hitherto researchers have not revealed enough about the people and projects at issue. Against this backdrop, this paper examines some key issues taking shape, while highlighting new frontiers for research and introducing the concept ‘data sovereignty’, which food sovereignty practitioners (and others) need to begin considering.
Journal Article Mass Media and American Politics, by Doris A. Graber Mass Media and American Politics by Doris A. Graber. Washington, D.C., Congressional Quarterly Press, 1980. 304 pp. $6.95. Martha Joynt Kumar Martha Joynt Kumar Towson State College Search for other works by this author on: Oxford Academic Google Scholar Political Science Quarterly, Volume 95, Issue 4, Winter 1980, Pages 701–702, https://doi.org/10.2307/2150629 Published: 15 December 1980
Grabbing and manipulating virtual objects is an important user interaction for immersive virtual environments. We present implementations and discussion of six techniques which allow manipulation of remote objects. A user study of these techniques was performed which revealed their characteristics and deficiencies, and led to the development of a new class of techniques. These hybrid techniques provide distinct advantages in terms of ease of use and efficiency because they consider the tasks of grabbing and manipulation separately. CR Categories and Subject Descriptors: I.3.7 [Computer Graphics]:Three-Dimensional Graphics and Realism - Virtual Reality; I.3.6 [Computer Graphics]:Methodology and Techniques - Interaction Techniques. 1 INTRODUCTION A defining feature of virtual reality (VR) is the ability to manipulate virtual objects interactively, rather than simply viewing a passive environment. This capability is desirable in many VR applications and is typically accomplished using ...
Contemporary large-scale land deals are widely understood as involving the expulsion of people who, in turn, struggle instinctively to resist dispossession This is certainly true in many instances. Yet this chain of events evidently does not always occur: large-scale land deals do not always result in people losing the land, and many of those who face expulsion do not necessarily respond with the kind of resistance often expected of them. Indeed, much evidence shows that the nature of and responses to big land deals can (and do) vary across and within ‘local communities’. Taking off analytically from a relatively narrow selection of cases, the expulsion–resistance scenario is too often assumed rather than demonstrated, thereby leaving many inconvenient facts undetected and unexplained. This suggests a need to step back and problematise the variable and uneven responses ‘from below’ to land grabbing, both within and between communities. This paper offers an initial exploration into why poor people affected by contemporary land deals (re)act the way they do, noting how issues and processes unite and divide them. This helps explain variation in political trajectories in the context of land grabbing today.
While the global rush to control land resources is well established, ‘power-grabs’ in relation to marine and coastal resources are less well researched. Under the banner of ‘blue growth’, such power-grabs are taking shape through global policy processes that purportedly align the needs of the poor with profit interests and climate change concerns. This contribution critically interrogates these policy proposals and situates them within broader neoliberalization of nature debates. It is argued that the policy proposals fail on their own terms and are a form of ‘antipolitics’ that precludes more radical visions of addressing environmental and climate change issues. In an attempt to challenge this, small-scale fishers’ movements are increasingly framing their opposition in terms of the broader struggle for ‘food sovereignty’.
Across the world, ‘green grabbing’ – the appropriation of land and resources for environmental ends – is an emerging process of deep and growing significance. The vigorous debate on ‘land grabbing’ already highlights instances where ‘green’ credentials are called upon to justify appropriations of land for food or fuel – as where large tracts of land are acquired not just for ‘more efficient farming’ or ‘food security’, but also to ‘alleviate pressure on forests’. In other cases, however, environmental green agendas are the core drivers and goals of grabs – whether linked to biodiversity conservation, biocarbon sequestration, biofuels, ecosystem services, ecotourism or ‘offsets’ related to any and all of these. In some cases these involve the wholesale alienation of land, and in others the restructuring of rules and authority in the access, use and management of resources that may have profoundly alienating effects. Green grabbing builds on well-known histories of colonial and neo-colonial resource alienation in the name of the environment – whether for parks, forest reserves or to halt assumed destructive local practices. Yet it involves novel forms of valuation, commodification and markets for pieces and aspects of nature, and an extraordinary new range of actors and alliances – as pension funds and venture capitalists, commodity traders and consultants, GIS service providers and business entrepreneurs, ecotourism companies and the military, green activists and anxious consumers among others find once-unlikely common interests. This collection draws new theorisation together with cases from African, Asian and Latin American settings, and links critical studies of nature with critical agrarian studies, to ask: To what extent and in what ways do ‘green grabs’ constitute new forms of appropriation of nature? How and when do circulations of green capital become manifest in actual appropriations on the ground – through what political and discursive dynamics? What are the implications for ecologies, landscapes and livelihoods? And who is gaining and who is losing – how are agrarian social relations, rights and authority being restructured, and in whose interests?