搜索结果：Exploratory research in clinical and social pharmacy

Texts reveal the subjects of interest in research fields, and the values, beliefs, and practices of researchers. In this study, texts are examined through bibliometric mapping and topic modeling to provide a birds eye view of the social dynamics associated with the diffusion of research synthesis methods in the contexts of Social Work and Women's Studies. Research synthesis texts are especially revealing because the methods, which include meta-analysis and systematic review, are reliant on the availability of past research and data, sometimes idealized as objective, egalitarian approaches to research evaluation, fundamentally tied to past research practices, and performed with the goal informing future research and practice. This study highlights the co-influence of past and subsequent research within research fields; illustrates dynamics of the diffusion process; and provides insight into the cultural contexts of research in Social Work and Women's Studies. This study suggests the potential to further develop bibliometric mapping and topic modeling techniques to inform research problem selection and resource allocation.

The competency of any intelligent agent is bounded by its formal account of the world in which it operates. Clinical AI lacks such an account. Existing frameworks address evaluation, regulation, or system design in isolation, without a shared model of the clinical world to connect them. We introduce the Clinical World Model, a framework that formalizes care as a tripartite interaction among Patient, Provider, and Ecosystem. To formalize how any agent, whether human or artificial, transforms information into clinical action, we develop parallel decision-making architectures for providers, patients, and AI agents, grounded in validated principles of clinical cognition. The Clinical AI Skill-Mix operationalizes competency through eight dimensions. Five define the clinical competency space (condition, phase, care setting, provider role, and task) and three specify how AI engages human reasoning (assigned authority, agent facing, and anchoring layer). The combinatorial product of these dimensions yields a space of billions of distinct competency coordinates. A central structural implication is that validation within one coordinate provides minimal evidence for performance in another, re

Objectives: Electronic health records (EHRs) are only a first step in capturing and utilizing health-related data - the challenge is turning that data into useful information. Furthermore, EHRs are increasingly likely to include data relating to patient outcomes, functionality such as clinical decision support, and genetic information as well, and, as such, can be seen as repositories of increasingly valuable information about patients' health conditions and responses to treatment over time. Methods: We describe a case study of 423 patients treated by Centerstone within Tennessee and Indiana in which we utilized electronic health record data to generate predictive algorithms of individual patient treatment response. Multiple models were constructed using predictor variables derived from clinical, financial and geographic data. Results: For the 423 patients, 101 deteriorated, 223 improved and in 99 there was no change in clinical condition. Based on modeling of various clinical indicators at baseline, the highest accuracy in predicting individual patient response ranged from 70-72% within the models tested. In terms of individual predictors, the Centerstone Assessment of Recovery Le

Social media plays a central role in shaping public opinion and behavior, yet performing experiments on these platforms and, in particular, on feed algorithms is becoming increasingly challenging. This guide offers practical recommendations for researchers developing and deploying field experiments focused on real-time reranking of social media feeds. The article is organized around two contributions. First, we provide an overview of an experimental method using web browser extensions that intercepts and reranks content in real time, enabling naturalistic reranking field experiments. We then describe feed interventions and measurements that this paradigm enables on participants' actual feeds, without requiring the involvement of social media platforms. Second, we offer concrete technical recommendations for intercepting and reranking social media feeds with minimal user-facing delay, and provide an open-source implementation. This document aims to summarize lessons learned in running field experiments on social media, provide concrete implementation details, and foster the ecosystem of independent social media research. Finally, we release the source code that serves as a blueprint

Estimation of social influence in networks can be substantially biased in observational studies due to homophily and network correlation in exposure to exogenous events. Randomized experiments, in which the researcher intervenes in the social system and uses randomization to determine how to do so, provide a methodology for credibly estimating of causal effects of social behaviors. In addition to addressing questions central to the social sciences, these estimates can form the basis for effective marketing and public policy. In this review, we discuss the design space of experiments to measure social influence through combinations of interventions and randomizations. We define an experiment as combination of (1) a target population of individuals connected by an observed interaction network, (2) a set of treatments whereby the researcher will intervene in the social system, (3) a randomization strategy which maps individuals or edges to treatments, and (4) a measurement of an outcome of interest after treatment has been assigned. We review experiments that demonstrate potential experimental designs and we evaluate their advantages and tradeoffs for answering different types of caus

Do different fields of knowledge require different research strategies? A numerical model exploring different virtual knowledge landscapes, revealed two diverging optimal search strategies. Trend following is maximized when the popularity of new discoveries determine the number of individuals researching it. This strategy works best when many researchers explore few large areas of knowledge. In contrast, individuals or small groups of researchers are better in discovering small bits of information in dispersed knowledge landscapes. Bibliometric data of scientific publications showed a continuous bipolar distribution of these strategies, ranging from natural sciences, with highly cited publications in journals containing a large number of articles, to the social sciences, with rarely cited publications in many journals containing a small number of articles. The natural sciences seem to adapt their research strategies to landscapes with large concentrated knowledge clusters, whereas social sciences seem to have adapted to search in landscapes with many small isolated knowledge clusters. Similar bipolar distributions were obtained when comparing levels of insularity estimated by indic

Decentralized Online Social Networks (DOSNs) represent a growing trend in the social media landscape, as opposed to the well-known centralized peers, which are often in the spotlight due to privacy concerns and a vision typically focused on monetization through user relationships. By exploiting open-source software, DOSNs allow users to create their own servers, or instances, thus favoring the proliferation of platforms that are independent yet interconnected with each other in a transparent way. Nonetheless, the resulting cooperation model, commonly known as the Fediverse, still represents a world to be fully discovered, since existing studies have mainly focused on a limited number of structural aspects of interest in DOSNs. In this work, we aim to fill a lack of study on user relations and roles in DOSNs, by taking two main actions: understanding the impact of decentralization on how users relate to each other within their membership instance and/or across different instances, and unveiling user roles that can explain two interrelated axes of social behavioral phenomena, namely information consumption and boundary spanning. To this purpose, we build our analysis on user networks

The rise of social media has fundamentally transformed how people engage in public discourse and form opinions. While these platforms offer unprecedented opportunities for democratic engagement, they have been implicated in increasing social polarization and the formation of ideological echo chambers. Previous research has primarily relied on observational studies of social media data or theoretical modeling approaches, leaving a significant gap in our understanding of how individuals respond to and are influenced by polarized online environments. Here we present a novel experimental framework for investigating polarization dynamics that allows human users to interact with LLM-based artificial agents in a controlled social network simulation. Through a user study with 122 participants, we demonstrate that this approach can successfully reproduce key characteristics of polarized online discourse while enabling precise manipulation of environmental factors. Our results provide empirical validation of theoretical predictions about online polarization, showing that polarized environments significantly increase perceived emotionality and group identity salience while reducing expressed

The ways of communication and social interactions are changing. Web users are becoming increasingly engaged with Online Social Networks (OSN), which has a significant impact on the relationship mechanisms between individuals and communities. Most OSN platforms have strict policies regarding data access, harming its usage in psychological and social phenomena studies, It is also impacting the development of computational methods to evaluate and improve social and individual well-being via the web. Aiming to fill this gap, we propose a platform that brings together social networks dynamics with forum features, altogether with gamification elements, targeting researchers interested in obtaining access to user's data to study psychological and social phenomena.

Social media is becoming an increasingly important data source for learning about breaking news and for following the latest developments of ongoing news. This is in part possible thanks to the existence of mobile devices, which allows anyone with access to the Internet to post updates from anywhere, leading in turn to a growing presence of citizen journalism. Consequently, social media has become a go-to resource for journalists during the process of newsgathering. Use of social media for newsgathering is however challenging, and suitable tools are needed in order to facilitate access to useful information for reporting. In this paper, we provide an overview of research in data mining and natural language processing for mining social media for newsgathering. We discuss five different areas that researchers have worked on to mitigate the challenges inherent to social media newsgathering: news discovery, curation of news, validation and verification of content, newsgathering dashboards, and other tasks. We outline the progress made so far in the field, summarise the current challenges as well as discuss future directions in the use of computational journalism to assist with social m

Identifying influencers in a given social network has become an important research problem for various applications, including accelerating the spread of information in viral marketing and preventing the spread of fake news and rumors. The literature contains a rich body of studies on identifying influential source spreaders who can spread their own messages to many other nodes. In contrast, the identification of influential brokers who can spread other nodes' messages to many nodes has not been fully explored. Theoretical and empirical studies suggest that involvement of both influential source spreaders and brokers is a key to facilitating large-scale information diffusion cascades. Therefore, this paper explores ways to identify influential brokers from a given social network. By using three social media datasets, we investigate the characteristics of influential brokers by comparing them with influential source spreaders and central nodes obtained from centrality measures. Our results show that (i) most of the influential source spreaders are not influential brokers (and vice versa) and (ii) the overlap between central nodes and influential brokers is small (less than 15%) in T

The continuous interest in the social network area contributes to the fast development of this field. The new possibilities of obtaining and storing data facilitate deeper analysis of the entire network, extracted social groups and single individuals as well. One of the most interesting research topic is the dynamics of social groups, it means analysis of group evolution over time. Having appropriate knowledge and methods for dynamic analysis, one may attempt to predict the future of the group, and then manage it properly in order to achieve or change this predicted future according to specific needs. Such ability would be a powerful tool in the hands of human resource managers, personnel recruitment, marketing, etc. The social group evolution consists of individual events and seven types of such changes have been identified in the paper: continuing, shrinking, growing, splitting, merging, dissolving and forming. To enable the analysis of group evolution a change indicator - inclusion measure was proposed. It has been used in a new method for exploring the evolution of social groups, called Group Evolution Discovery (GED). The experimental results of its use together with the compa

Processing information locked within clinical health records is a challenging task that remains an active area of research in biomedical NLP. In this work, we evaluate a broad set of machine learning techniques ranging from simple RNNs to specialised transformers such as BioBERT on a dataset containing clinical notes along with a set of annotations indicating whether a sample is cancer-related or not. Furthermore, we specifically employ efficient fine-tuning methods from NLP, namely, bottleneck adapters and prompt tuning, to adapt the models to our specialised task. Our evaluations suggest that fine-tuning a frozen BERT model pre-trained on natural language and with bottleneck adapters outperforms all other strategies, including full fine-tuning of the specialised BioBERT model. Based on our findings, we suggest that using bottleneck adapters in low-resource situations with limited access to labelled data or processing capacity could be a viable strategy in biomedical text mining. The code used in the experiments are going to be made available at https://github.com/omidrohanian/bottleneck-adapters.

In 2016, a network of social media accounts animated by Russian operatives attempted to divert political discourse within the American public around the presidential elections. This was a coordinated effort, part of a Russian-led complex information operation. Utilizing the anonymity and outreach of social media platforms Russian operatives created an online astroturf that is in direct contact with regular Americans, promoting Russian agenda and goals. The elusiveness of this type of adversarial approach rendered security agencies helpless, stressing the unique challenges this type of intervention presents. Building on existing scholarship on the functions within influence networks on social media, we suggest a new approach to map those types of operations. We argue that pretending to be legitimate social actors obliges the network to adhere to social expectations, leaving a social footprint. To test the robustness of this social footprint we train artificial intelligence to identify it and create a predictive model. We use Twitter data identified as part of the Russian influence network for training the artificial intelligence and to test the prediction. Our model attains 88% pred

Although beneficial information abounds on social media, the dissemination of harmful information such as so-called ``fake news'' has become a serious issue. Therefore, many researchers have devoted considerable effort to limiting the diffusion of harmful information. A promising approach to limiting diffusion of such information is link deletion methods in social networks. Link deletion methods have been shown to be effective in reducing the size of information diffusion cascades generated by synthetic models on a given social network. In this study, we evaluate the effectiveness of link deletion methods by using actual logs of retweet cascades, rather than by using synthetic diffusion models. Our results show that even after deleting 10\%--50\% of links from a social network, the size of cascades after link deletion is estimated to be only 50\% the original size under the optimistic estimation, which suggests that the effectiveness of the link deletion strategy for suppressing information diffusion is limited. Moreover, our results also show that there is a considerable number of cascades with many seed users, which renders link deletion methods inefficient.

The survey data sets are important sources of data and their successful exploitation is of key importance for informed policy-decision making. We present how a survey analysis approach initially developed for customer satisfaction research in marketing can be adapted for the introduction of clinical pharmacy services into hospital. We use two analytical approaches to extract relevant managerial consequences. With OrdEval algorithm we first evaluate the importance of competences for the users of clinical pharmacy and extract their nature according to the users expectations. Next, we build a model for predicting a successful introduction of clinical pharmacy to the clinical departments. We the wards with the highest probability of successful cooperation with a clinical pharmacist. We obtain useful managerially relevant information from a relatively small sample of highly relevant respondents. We show how the OrdEval algorithm exploits the information hidden in the ordering of class and attribute values and their inherent correlation. Its output can be effectively visualized and complemented with confidence intervals.

Objective: Integrating EHR data with other resources is essential in rare disease research due to low disease prevalence. Such integration is dependent on the alignment of ontologies used for data annotation. The International Classification of Diseases (ICD) is used to annotate clinical diagnoses; the Human Phenotype Ontology (HPO) to annotate phenotypes. Although these ontologies overlap in biomedical entities described, the extent to which they are interoperable is unknown. We investigate how well aligned these ontologies are and whether such alignments facilitate EHR data integration. Materials and Methods: We conducted an empirical analysis of the coverage of mappings between ICD and HPO. We interpret this mapping coverage as a proxy for how easily clinical data can be integrated with research ontologies such as HPO. We quantify how exhaustively ICD codes are mapped to HPO by analyzing mappings in the UMLS Metathesaurus. We analyze the proportion of ICD codes mapped to HPO within a real-world EHR dataset. Results and Discussion: Our analysis revealed that only 2.2% of ICD codes have direct mappings to HPO in UMLS. Within our EHR dataset, less than 50% of ICD codes have mapping

Coordinated online behaviors are an essential part of information and influence operations, as they allow a more effective disinformation's spread. Most studies on coordinated behaviors involved manual investigations, and the few existing computational approaches make bold assumptions or oversimplify the problem to make it tractable. Here, we propose a new network-based framework for uncovering and studying coordinated behaviors on social media. Our research extends existing systems and goes beyond limiting binary classifications of coordinated and uncoordinated behaviors. It allows to expose different coordination patterns and to estimate the degree of coordination that characterizes diverse communities. We apply our framework to a dataset collected during the 2019 UK General Election, detecting and characterizing coordinated communities that participated in the electoral debate. Our work conveys both theoretical and practical implications and provides more nuanced and fine-grained results for studying online information manipulation.

Specialised pre-trained language models are becoming more frequent in NLP since they can potentially outperform models trained on generic texts. BioBERT and BioClinicalBERT are two examples of such models that have shown promise in medical NLP tasks. Many of these models are overparametrised and resource-intensive, but thanks to techniques like Knowledge Distillation (KD), it is possible to create smaller versions that perform almost as well as their larger counterparts. In this work, we specifically focus on development of compact language models for processing clinical texts (i.e. progress notes, discharge summaries etc). We developed a number of efficient lightweight clinical transformers using knowledge distillation and continual learning, with the number of parameters ranging from 15 million to 65 million. These models performed comparably to larger models such as BioBERT and ClinicalBioBERT and significantly outperformed other compact models trained on general or biomedical data. Our extensive evaluation was done across several standard datasets and covered a wide range of clinical text-mining tasks, including Natural Language Inference, Relation Extraction, Named Entity Reco