Research in the mental health field has focused on exploration and implementation of digital interventions both in research and society. However, demographic and mental health factors that may influence engagement with research on such interventions have not been explored. This study aims to investigate the relationship between demographics, signs of mental disorders, and interest in participating in an intervention study. Using data collected in the Swedish arm of the World Health Organization’s World Mental Health International College Student (WHO-WMH-ICS) initiative (n = 9140), we conducted a multinomial logistic regression to assess relationships between these factors. Older age, as well as female and non-binary gender identities, were factors significantly associated with increased interest in the intervention study. Treatment flags, indicating fulfilment of criteria for possible mental disorder diagnosis, were significantly associated with clear interest (“yes” response) in intervention research for five of the 15 treatment flags: depression, general anxiety, social anxiety, panic disorder and self-harm. Possible interest (“maybe” response) was also indicated for four of these, excluding general anxiety. These findings may facilitate a better-informed approach to recruiting student participants for treatment research, enhancing unbiased recruitment practices, reducing treatment gaps, and increasing engagement in digital intervention studies for improved mental health.
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This evaluation study assessed the learning outcomes of a newly developed Leadership and Communication course for premedical students and explored the potential of interprofessional education through collaborative activities with nursing students. To evaluate the learning outcomes of a leadership course involving 99 premedical students, we analyzed two distinct data sources. First, we reviewed the results of an anonymous course evaluation conducted by the university, with 98 students responding. Second, we analyzed 376 reflective notes submitted by 99 premedical students regarding four collaborative learning activities with 70 nursing students. After excluding unreliable or non-submitted reflective notes, a total of 376 reflective notes were included in the analysis. Textual analysis was performed using Voyant Tools, a web-based platform that enables rapid visualization and analysis of qualitative data. Course evaluation revealed positive response rates averaging 60-70% across all course components. However, the students requested improvements in the operational aspects of this first interdisciplinary course format involving students from different departments. Textual analysis of reflection reports identified 'communication' as the most frequently mentioned keyword, often associated with 'important.' Analysis revealed core IPE competency for Interprofessional Collaborative Practice (IPCP) in order of frequency: 'communication,' 'teams and teamwork,' 'roles and responsibilities,' and 'values and ethics.' Two specific activities-special lectures and hospital development plans-effectively encompassed all core IPE competency keywords. Simple textual analysis of student-submitted reflective journals combined with institutional course evaluation reviews enabled comprehensive and nuanced assessment of course outcomes. The integration of selective collaborative activities with nursing students within existing course structures proved to be a pragmatic alternative that simultaneously enhanced premedical students' learning outcomes in leadership and communication, mitigated implementation challenges inherent to comprehensive interprofessional education (IPE) programs, and fostered deeper interprofessional understanding.
Missed outpatient appointments are commonly framed as a problem of patient compliance and responsibility (non-attendance). This paper challenges that assumption by demonstrating how communication practices and organisational structures shape experiences of care and access in Southern Denmark. Drawing on participatory action research, the study explores barriers and enablers of attendance from the perspectives of patients and healthcare professionals and identifies potential measures to reduce missed appointments. We adopt a multilevel participatory approach. As part of participatory action research, we conducted two workshops and two focus groups, working closely with Danish and immigrant patients, professional interpreters, health care administrative professionals, and technical specialists to explore barriers and enablers of outpatient attendance. Participants were purposively recruited through patient and professional networks and via digital platforms, including LinkedIn and FB. We complemented the study with ethnographic observations and semi-structured interviews with head nurses and medical secretaries in orthopaedic surgical departments at two regional hospitals. Seven patients were additionally interviewed. Field notes, workshop transcripts, and interview data were analysed using reflexive thematic analysis to identify patterns of meaning, and barriers and enablers of attendance, across participant groups and organisational contexts. The study identified a range of interrelated barriers to attendance grouped into eight overarching themes: (1) structural barriers related to digital and logistic inequalities, (2) systemic and organisational barriers, (3) communication barriers, (4) psychological or illness-related barriers, (5) cultural and language barriers, (6) emotional barriers; (7) relational barriers, and (8) barriers related to physical space and wayfinding. Continuity of care and clear and direct communication were identified as factors contributing to attendance. Suggestions for improving attendance included strengthening cross-departmental collaboration, adopting more person-centred communication, and implementing multilingual communication tools. Non-attendance may stem from communication failures, systemic limitations, and structural barriers within the healthcare system, rather than solely from poor patient compliance. Although most patients make considerable efforts to attend appointments, these efforts may be overlooked within the standardized healthcare system, which prioritizes digital solutions and consumer-oriented care logic. Improving attendance requires addressing organisational and systemic barriers affecting care delivery and access, including rigid scheduling systems, hospital-initiated cancellations and rescheduling, limited coordination across departments, and inadequate information provision. Efforts to reduce missed appointments must also address digital and language inequalities, illness-related limitations and needs, and ensure that patient communication is clear, respectful, and free from stigma or blame.
Emergency rooms prioritize rapid, life-saving interventions, often at the expense of patients’ psychosocial and existential needs. Patients in these settings are particularly vulnerable, yet such needs are frequently overlooked. Despite growing emphasis on person-centered care, knowledge of how existential needs (e.g. fear, anxiety, vulnerability) are expressed and addressed in emergency rooms remains limited. This study aims to describe how existential needs are expressed in the emergency room context. A qualitative secondary analysis was conducted using 108 field notes, 14 registered nurse interviews, and 15 patient interviews viewing emergency room care through a Fundamentals of Care framework lens. An inductive approach was inspired by key existential concepts described in a review and relevant to acute care. Reflexive thematic analysis was applied to each dataset, followed by cross-data comparison to identify patterns of existential needs. The secondary analysis resulted in four themes; Existential vulnerability in a technical environment, Ensuring trust through presence and communication, Violations of privacy and dignity, and Moments of meaning-making through connection showing that existential needs in the emergency room are widespread and closely connected to both patients’ experiences and registered nurses’ care practices. Patients faced sudden transitions, fear, and emotional vulnerability, while registered nurses balanced these needs with organizational constraints. Existential concerns were expressed verbally and non-verbally and shaped by the environment, communication, and presence. Even brief, attentive encounters were experienced as meaningful and created a sense of safety in the stressful clinical setting. Addressing existential needs is integral to emergency care. Recognition and responsive care can mitigate patients’ emotional isolation and enhance safety, despite organizational constraints, highlighting the importance of integrating existential support with medical treatment. The organization should enable healthcare professionals to recognize and respond to existential needs as an integrated part of patient assessment and care interventions, supporting a more person-centered and holistic care in acute environments. This study highlights the importance of addressing existential needs within the emergency room, for both patients and registered nurses. Organizational constraints and ethical tensions challenge person-centered fundamental care, while underscoring safety as a crucial condition for meaningful and compassionate encounters. The findings offer guidance for emergency care professionals on integrating existential and relational awareness into practice, education, and policy. Clinical trial number: Not applicable.
Precision beekeeping is an integral part of precision agriculture, which relies on sensor technologies and high-quality datasets to quantify and optimize ecosystem services such as crop pollination. To support reproducible research and the planning and evaluation of crop pollination campaigns in precision beekeeping, we release a time-series dataset that characterizes colony dynamics before, during, and after pollination, using sunflower as a case study. We release synchronized, non-invasive time series from nine smart hives (Apis mellifera) monitored in Ukraine (Europe/Kyiv) from 01 May to 31 Aug 2024, including a sunflower pollination service window (07-23 Jul 2024) and a documented attractant intervention. Sensors record hive weight, in-hive and ambient temperature, in-hive and ambient relative humidity, and device signals (processor temperature and stabilized solar voltage). The repository includes raw telemetry exports, cleaned hourly series aligned to a fixed local time grid, and a beekeeper event log, together with reproducible scripts and a documented processing protocol.
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Nationally representative data are essential for understanding the causes, consequences, and costs of dementia and mild cognitive impairment (MCI) and for informing policy and care planning. This study aimed to describe methodological considerations in applying the Health and Retirement Study Harmonised Cognitive Assessment Protocol (HRS-HCAP) cognitive domain structure and diagnostic algorithm to the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA-HCAP), and to generate harmonised estimates of the prevalence of dementia and mild cognitive impairment (MCI) in a nationally representative sample. A total of 1,037 participants aged ≥ 65 years completed NICOLA-HCAP. Five cognitive domains were identified, all loading onto a second-order general cognitive performance factor: orientation (0.903), memory (0.855), executive function (0.893), language-fluency (0.962), and visuospatial ability (0.812). Model fit was acceptable (SRMR = 0.065; RMSEA = 0.047; CFI = 0.916; TLI = 0.906). Following classification, 6.2% of participants were classified with dementia and 15.8% as MCI. Methodological modifications addressed software differences, normative sample derivation, and cohort-specific adjustments. These findings provide preliminary support for HCAP as a framework for producing harmonised estimates of cognitive status. NICOLA-HCAP will facilitate future investigation of modifiable risk factors for dementia in community-dwelling older adults. Validation studies are required to determine whether resulting classifications are fit for purpose.
Concerns have been raised about doctors shifting jobs from non-profit to for-profit healthcare, leaving non-profit organisations understaffed. This study explores the extent and underlying reasons for such job transitions. A 2024 national survey of Norwegian doctors (n = 1973; 78% response) examined job shifts from non-profit to for-profit healthcare over the past 2 years. Fifty-one doctors (2.6%) had shifted from non-profit to for-profit healthcare in the past 2 years; 19 (37%) were still working in for-profit healthcare. A third of the doctors working in non-profit healthcare had considered switching to for-profit work (450/1517). This group was younger, less satisfied with their jobs, and reported higher sickness absence. Working hours were most often cited as a very important reason for shifting jobs.
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This study aimed to determine the seasonal variations in frequency and outcomes of HBSS-related morbidities admitted over two years into a tertiary hospital emergency ward in Lagos, Nigeria. A retrospective descriptive study was conducted using hospital records of HBSS patients admitted into the emergency ward from January 2021 to December 2022. Data on demographics, clinical diagnosis, season of admission, and outcomes were extracted and analyzed using Epi Info version 7. Associations were tested using Chi-square at a significance level of p < 0.05. A total of 132 HBSS admissions were recorded (63 in 2021 and 69 in 2022), with a male predominance (54.5%), while the majority aged between 20 and 29 years (55.3%). Vaso-occlusive crisis (VOC) was the most common morbidity (80.6%). Seasonal variations in admissions occurred, which peaked during rainy season months (May, June). The percentage of in-hospital mortality was 5.3% and mortality was seen to be significantly higher among stroke cases (50.0%) than other HBSS morbidities (p = 0.046). Seasonal patterns influenced HBSS morbidity, with VOCs predominating especially during the rainy season.
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We previously reported that hydrolysis products (HP) generated from total lipoproteins via lipoprotein lipase (LPL) significantly changed the transcriptome of human macrophages, including an increased representation of small nucleolar RNAs, but we did not extensively examine small-coding RNAs in general. The expression of small nucleolar RNAs was previously reported to increase in cardiomyocytes through an increase of reactive oxygen species (ROS) generation by NADPH oxidase (NOX). Thus, we hypothesized that the HP induced ROS production in macrophages through NOX activity, resulting in changes to small RNA transcripts. We examined whether very low-density lipoprotein HP could induce ROS production via NOX within the THP-1 human macrophage model. We showed that ROS production was indeed increased, and it was in-part due to NOX. We further examined changes to small RNA expression using RNA-seq in the absence or presence of HP, and whether those changes could be reversed by NOX inhibition. We identified eight differentially expressed small RNAs: three with differed expression in response to HP, and five with differed expression in response to NOX inhibition in the presence of HP. We conclude that LPL drives ROS production in macrophages via NOX to subsequently influence small RNA expression profiles.
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