搜索结果：Aviation, space, and environmental medicine

Medicine, including fields in healthcare and life sciences, has seen a flurry of quantum-related activities and experiments in the last few years (although biology and quantum theory have arguably been entangled ever since Schrödinger's cat). The initial focus was on biochemical and computational biology problems; recently, however, clinical and medical quantum solutions have drawn increasing interest. The rapid emergence of quantum computing in health and medicine necessitates a mapping of the landscape. In this review, clinical and medical proof-of-concept quantum computing applications are outlined and put into perspective. These consist of over 40 experimental and theoretical studies. The use case areas span genomics, clinical research and discovery, diagnostics, and treatments and interventions. Quantum machine learning (QML) in particular has rapidly evolved and shown to be competitive with classical benchmarks in recent medical research. Near-term QML algorithms have been trained with diverse clinical and real-world data sets. This includes studies in generating new molecular entities as drug candidates, diagnosing based on medical image classification, predicting patient pe

Publication selection bias undermines the systematic accumulation of evidence. To assess the extent of this problem, we survey over 68,000 meta-analyses containing over 700,000 effect size estimates from medicine (67,386/597,699), environmental sciences (199/12,707), psychology (605/23,563), and economics (327/91,421). Our results indicate that meta-analyses in economics are the most severely contaminated by publication selection bias, closely followed by meta-analyses in environmental sciences and psychology, whereas meta-analyses in medicine are contaminated the least. After adjusting for publication selection bias, the median probability of the presence of an effect decreased from 99.9% to 29.7% in economics, from 98.9% to 55.7% in psychology, from 99.8% to 70.7% in environmental sciences, and from 38.0% to 29.7% in medicine. The median absolute effect sizes (in terms of standardized mean differences) decreased from d = 0.20 to d = 0.07 in economics, from d = 0.37 to d = 0.26 in psychology, from d = 0.62 to d = 0.43 in environmental sciences, and from d = 0.24 to d = 0.13 in medicine.

This study investigates the interconnectivity of firms and Environmental Justice Organizations (EJOs) involved in socio-environmental conflicts worldwide, using data from the Environmental Justice Atlas (EJAtlas). By constructing a multilayer network that links firms, conflicts, and EJOs, the research applies social network analysis to evaluate the simultaneous involvement of these actors across multiple disputes. Both projected networks of firms and EJOs have been analysed by aggregating nodes by categories and countries to reveal structural differences. Findings reveal a stark contrast between the interconnectedness of firms and EJOs. Multinational corporations form a cohesive global network, enabling them to coordinate strategies and exert influence across regions. Conversely, EJOs are fragmented, often operating in isolated clusters with limited interconnection but forming a robust, decentralized and self-organized global network. Firms network present a strong dependence on pertaining conflict category while EJOs network does not depend on conflict category. This structural difference suggests a risk of systemic and structural coordination for firms towards exploitative expans

Model Medicine is the science of understanding, diagnosing, treating, and preventing disorders in AI models, grounded in the principle that AI models -- like biological organisms -- have internal structures, dynamic processes, heritable traits, observable symptoms, classifiable conditions, and treatable states. This paper introduces Model Medicine as a research program, bridging the gap between current AI interpretability research (anatomical observation) and the systematic clinical practice that complex AI systems increasingly require. We present five contributions: (1) a discipline taxonomy organizing 15 subdisciplines across four divisions -- Basic Model Sciences, Clinical Model Sciences, Model Public Health, and Model Architectural Medicine; (2) the Four Shell Model (v3.3), a behavioral genetics framework empirically grounded in 720 agents and 24,923 decisions from the Agora-12 program, explaining how model behavior emerges from Core--Shell interaction; (3) Neural MRI (Model Resonance Imaging), a working open-source diagnostic tool mapping five medical neuroimaging modalities to AI interpretability techniques, validated through four clinical cases demonstrating imaging, compari

We present a community-wide effort to develop a strategy and action plan to advance heliophysics and space weather modeling through open science. While open science has the potential to enhance the quality and pace of scientific discovery, its application to scientific modeling requires more careful consideration regarding open data and open software guidelines, as scientific models differ significantly from data analysis software. We gathered feedback from modeling teams worldwide through a living survey and discussion sessions at the 2024 Open Science Workshop in College Park, USA, and at the 2025 COSPAR ISWAT Working Meeting in Cape Canaveral, USA. We complement these findings with lessons learned from almost 25 years of experience at the Community Coordinated Modeling Center in enabling open use of models. We identify key roadblocks in current open science practices and guidelines and offer recommendations for future progress across four overlapping themes: open use of models and simulation results, open validation, open development, and open collaboration. An essential outcome of the discussion is the need for model developers and model users to speak with a united voice and p

This study examines the clinical decision-making processes in Traditional East Asian Medicine (TEAM) by reinterpreting pattern identification (PI) through the lens of dimensionality reduction. Focusing on the Eight Principle Pattern Identification (EPPI) system and utilizing empirical data from the Shang-Han-Lun, we explore the necessity and significance of prioritizing the Exterior-Interior pattern in diagnosis and treatment selection. We test three hypotheses: whether the Ext-Int pattern contains the most information about patient symptoms, represents the most abstract and generalizable symptom information, and facilitates the selection of appropriate herbal prescriptions. Employing quantitative measures such as the abstraction index, cross-conditional generalization performance, and decision tree regression, our results demonstrate that the Exterior-Interior pattern represents the most abstract and generalizable symptom information, contributing to the efficient mapping between symptom and herbal prescription spaces. This research provides an objective framework for understanding the cognitive processes underlying TEAM, bridging traditional medical practices with modern computat

With the increasing interest in deploying Artificial Intelligence in medicine, we previously introduced HAIM (Holistic AI in Medicine), a framework that fuses multimodal data to solve downstream clinical tasks. However, HAIM uses data in a task-agnostic manner and lacks explainability. To address these limitations, we introduce xHAIM (Explainable HAIM), a novel framework leveraging Generative AI to enhance both prediction and explainability through four structured steps: (1) automatically identifying task-relevant patient data across modalities, (2) generating comprehensive patient summaries, (3) using these summaries for improved predictive modeling, and (4) providing clinical explanations by linking predictions to patient-specific medical knowledge. Evaluated on the HAIM-MIMIC-MM dataset, xHAIM improves average AUC from 79.9% to 90.3% across chest pathology and operative tasks. Importantly, xHAIM transforms AI from a black-box predictor into an explainable decision support system, enabling clinicians to interactively trace predictions back to relevant patient data, bridging AI advancements with clinical utility.

The Oxford English Dictionary defines precision medicine as "medical care designed to optimize efficiency or therapeutic benefit for particular groups of patients, especially by using genetic or molecular profiling." It is not an entirely new idea: physicians from ancient times have recognized that medical treatment needs to consider individual variations in patient characteristics. However, the modern precision medicine movement has been enabled by a confluence of events: scientific advances in fields such as genetics and pharmacology, technological advances in mobile devices and wearable sensors, and methodological advances in computing and data sciences. This chapter is about bandit algorithms: an area of data science of special relevance to precision medicine. With their roots in the seminal work of Bellman, Robbins, Lai and others, bandit algorithms have come to occupy a central place in modern data science ( Lattimore and Szepesvari, 2020). Bandit algorithms can be used in any situation where treatment decisions need to be made to optimize some health outcome. Since precision medicine focuses on the use of patient characteristics to guide treatment, contextual bandit algorith

The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt pathway. In this chapter we use the Wnt pathway to showcase current mathematical and statistical techniques that enable modelers to gain insight into (models of) gene regulation, and generate testable predictions. We introduce a range of modeling frameworks, but focus on ordinary differential equation (ODE) models since they remain the most widely used approach in systems biology and medicine and continue to offer great potential. We present methods for the analysis of a single model, comprising applications of standard dynamical systems approaches such as nondimensionalization, steady state, asymptotic and sensitivity analysis, and more recent statistical and algebraic approaches to compare models with data. We present parameter estimation and model comparison techniques, focusing on Bayesian analysis and coplanarity via algebraic geometry. Our intention is that this (non exhaustive) review may serve as a useful starting point for the analysis of models in systems medicine.

Real and effective regulation of contributions to greenhouse gas emissions and pollutants requires unbiased and truthful monitoring. Blockchain has emerged not only as an approach that provides verifiable economical interactions but also as a mechanism to keep the measurement, monitoring, incentivation of environmental conservationist practices and enforcement of policy. Here, we present a survey of areas in what blockchain has been considered as a response to concerns on keeping an accurate recording of environmental practices to monitor levels of pollution and management of environmental practices. We classify the applications of blockchain into different segments of concerns, such as greenhouse gas emissions, solid waste, water, plastics, food waste, and circular economy, and show the objectives for the addressed concerns. We also classify the different blockchains and the explored and designed properties as identified for the proposed solutions. At the end, we provide a discussion about the niches and challenges that remain for future research.

Safety is the main concern in the aviation industry, where even minor operational issues can lead to serious consequences. This study addresses the need for comprehensive aviation accident analysis by leveraging natural language processing (NLP) and advanced AI models to classify the phase of flight from unstructured aviation accident analysis narratives. The research aims to determine whether the phase of flight can be inferred from narratives of post-accident events using NLP techniques. The classification performance of various deep learning models was evaluated. For single RNN-based models, LSTM achieved an accuracy of 63%, precision 60%, and recall 61%. BiLSTM recorded an accuracy of 64%, precision 63%, and a recall of 64%. GRU exhibited balanced performance with an accuracy and recall of 60% and a precision of 63%. Joint RNN-based models further enhanced predictive capabilities. GRU-LSTM, LSTM-BiLSTM, and GRU-BiLSTM demonstrated accuracy rates of 62%, 67%, and 60%, respectively, showcasing the benefits of combining these architectures. To provide a comprehensive overview of model performance, single and combined models were compared in terms of the various metrics. These resu

The space-borne gravitational wave detectors such as TianQin offers a new window to test General Relativity by observing the early inspiral phase of stellar-mass binary black holes. A key concern arises if these stellar-mass binary black holes reside in gaseous environments such as active galactic nucleus accretion disks, where environmental effects imprint detectable modulations on the gravitational waveform. Using Bayesian inference on simulated signals containing both environmental and dipole deviation, we have assessed the extent to which the presence of environmental effects affects the detectability of dipole radiation. Our results demonstrate that even in the presence of strong environmental coupling, the dipole parameter can be recovered with high precision, and the evidence for dipole radiation remains distinguishable. Crucially, we find that the existence of environmental effects does not fundamentally impede the identification of dipole radiation, provided both effects are simultaneously modelled in the inference process. This study establishes that future tests of modified gravity with space-borne observatories can remain robust even for sources in astrophysical environ

Geospatial analysis offers large potential for better understanding, modelling and visualizing our natural and artificial ecosystems, using Internet of Things as a pervasive sensing infrastructure. This paper performs a review of research work based on the IoT, in which geospatial analysis has been employed in environmental informatics. Six different geospatial analysis methods have been identified, presented together with 26 relevant IoT initiatives adopting some of these techniques. Analysis is performed in relation to the type of IoT devices used, their deployment status and data transmission standards, data types employed, and reliability of measurements. This paper scratches the surface of this combination of technologies and techniques, providing indications of how IoT, together with geospatial analysis, are currently being used in the domain of environmental research.

Medical image analysis plays a key role in precision medicine as it allows the clinicians to identify anatomical abnormalities and it is routinely used in clinical assessment. Data curation and pre-processing of medical images are critical steps in the quantitative medical image analysis that can have a significant impact on the resulting model performance. In this paper, we introduce a precision-medicine-toolbox that allows researchers to perform data curation, image pre-processing and handcrafted radiomics extraction (via Pyradiomics) and feature exploration tasks with Python. With this open-source solution, we aim to address the data preparation and exploration problem, bridge the gap between the currently existing packages, and improve the reproducibility of quantitative medical imaging research.

Safety is a critical aspect of the air transport system given even slight operational anomalies can result in serious consequences. To reduce the chances of aviation safety occurrences, accidents and incidents are reported to establish the root cause, propose safety recommendations etc. However, analysis narratives of the pre-accident events are presented using human-understandable, raw, unstructured, text that a computer system cannot understand. The ability to classify and categorise safety occurrences from their textual narratives would help aviation industry stakeholders make informed safety-critical decisions. To classify and categorise safety occurrences, we applied natural language processing (NLP) and AI (Artificial Intelligence) models to process text narratives. The study aimed to answer the question. How well can the damage level caused to the aircraft in a safety occurrence be inferred from the text narrative using natural language processing. The classification performance of various deep learning models including LSTM, BLSTM, GRU, sRNN, and combinations of these models including LSTM and GRU, BLSTM+GRU, sRNN and LSTM, sRNN and BLSTM, sRNN and GRU, sRNN and BLSTM and G

The air transport system recognizes the criticality of safety, as even minor anomalies can have severe consequences. Reporting accidents and incidents play a vital role in identifying their causes and proposing safety recommendations. However, the narratives describing pre-accident events are presented in unstructured text that is not easily understood by computer systems. Classifying and categorizing safety occurrences based on these narratives can support informed decision-making by aviation industry stakeholders. In this study, researchers applied natural language processing (NLP) and artificial intelligence (AI) models to process text narratives to classify the flight phases of safety occurrences. The classification performance of two deep learning models, ResNet and sRNN was evaluated, using an initial dataset of 27,000 safety occurrence reports from the NTSB. The results demonstrated good performance, with both models achieving an accuracy exceeding 68%, well above the random guess rate of 14% for a seven-class classification problem. The models also exhibited high precision, recall, and F1 scores. The sRNN model greatly outperformed the simplified ResNet model architecture u

We develop a time series model to forecast weekly peak power demand for three main states of Australia for a yearly time-scale, and show the crucial role of environmental factors in improving the forecasts. More precisely, we construct a seasonal autoregressive integrated moving average (SARIMA) model and reinforce it by employing the exogenous environmental variables including, maximum temperature, minimum temperature, and solar exposure. The estimated hybrid SARIMA-regression model exhibits an excellent mean absolute percentage error (MAPE) of 3.41%. Moreover, our analysis demonstrates the importance of the environmental factors by showing a remarkable improvement of 46.3% in MAPE for the hybrid model over the crude SARIMA model which merely includes the power demand variables. In order to illustrate the efficacy of our model, we compare our outcome with the state-of-the-art machine learning methods in forecasting. The results reveal that our model outperforms the latter approach.

Recent advances in miniaturization and commercial availability of critical satellite subsystems and detector technology have made small satellites (SmallSats, including CubeSats) an attractive, low-cost potential solution for space weather research and operational needs. Motivated by the 1st International Workshop on SmallSats for Space Weather Research and Forecasting, held in Washington, DC on 1-4 August 2017, we discuss the need for advanced space weather measurement capabilities, driven by analyses from the World Meteorological Organization (WMO), and how SmallSats can efficiently fill these measurement gaps. We present some current, recent missions and proposed/upcoming mission concepts using SmallSats that enhance space weather research and provide prototyping pathways for future operational applications; how they relate to the WMO requirements; and what challenges remain to be overcome to meet the WMO goals and operational needs in the future. With additional investment from cognizant funding agencies worldwide, SmallSats -- including standalone missions and constellations -- could significantly enhance space weather research and, eventually, operations, by reducing costs an

Nanotechnology has emerged as a transformative force across multiple industries, enhancing materials, improving instrumentation precision, and developing intelligent systems. This review explores various nanotechnology applications, including advancements in materials science, healthcare, energy storage, environmental monitoring, and robotics. Nanomaterials, such as carbon nanotubes and graphene, offer significant improvements in fields like energy generation and medicine, while nanosensors revolutionize environmental and industrial monitoring. Micro and nano robots provide automation solutions across industries. By expanding beyond space exploration, this review highlights the far-reaching potential of nanotechnology to reshape industries through interdisciplinary collaboration and innovation.