This study investigates the application of novel model architectures and large-scale foundational models in temporal series analysis of lower limb rehabilitation motion data, aiming to leverage advancements in machine learning and artificial intelligence to empower active rehabilitation guidance strategies for post-stroke patients in limb motor function recovery. Utilizing the SIAT-LLMD dataset of lower limb movement data proposed by the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, we systematically elucidate the implementation and analytical outcomes of the innovative xLSTM architecture and the foundational model Lag-Llama in short-term temporal prediction tasks involving joint kinematics and dynamics parameters. The research provides novel insights for AI-enabled medical rehabilitation applications, demonstrating the potential of cutting-edge model architectures and large-scale models in rehabilitation medicine temporal prediction. These findings establish theoretical foundations for future applications of personalized rehabilitation regimens, offering significant implications for the development of customized therapeutic interventions in clinical pract
Configurable robots are made up of robotic modules that can be assembled or can configure themselves into multiple robot configurations. In this research plan, a method for upper-body rehabilitation will be discussed in the form of a modular robot with different morphologies. The advantage and superiority of designing an example of a robotic module for upper body rehabilitation is the ability to reset the modular robot system. In this research, a number of modules will be designed and implemented according to the needs of one-hand rehabilitation with different degrees of freedom. The design modules' performance and efficiency will be evaluated by simulating, making samples, and testing them. This article's research includes presenting a modular upper body rehabilitation robot in the wrist, elbow, and shoulder areas, as well as providing a suitable kinematic and dynamic model of the upper body rehabilitation robot to determine human-robot interaction forces and movement. The research also involves analyzing the mathematical model of the upper body rehabilitation robot to identify advanced control strategies that rely on force control and torque control. After reviewing the articles
In recent years, gamification has become very popular for rehabilitating different cognitive and motor problems. It has been shown that rehabilitation is effective when it starts early enough and it is intensive and repetitive. However, the success of rehabilitation depends also on the motivation and perseverance of patients during treatment. Adding serious games to the rehabilitation procedure will help the patients to overcome the monotonicity of the treatment procedure. On the other hand, if a variety of games can be used with a robotic rehabilitation system, it will help to define tasks with different levels of difficulty with greater variety. In this paper we introduce a procedure for connecting a rehabilitation robot to several web-based games. In other words, an interface is designed that connects the robot to a computer through a USB port. To validate the usefulness of the proposed approach, a researcher designed survey was used to get feedback from several users. The results demonstrate that having several games besides rehabilitation makes the procedure of rehabilitation entertaining.
What does Artificial Intelligence (AI) have to contribute to health care? And what should we be looking out for if we are worried about its risks? In this paper we offer a survey, and initial evaluation, of hopes and fears about the applications of artificial intelligence in medicine. AI clearly has enormous potential as a research tool, in genomics and public health especially, as well as a diagnostic aid. It's also highly likely to impact on the organisational and business practices of healthcare systems in ways that are perhaps under-appreciated. Enthusiasts for AI have held out the prospect that it will free physicians up to spend more time attending to what really matters to them and their patients. We will argue that this claim depends upon implausible assumptions about the institutional and economic imperatives operating in contemporary healthcare settings. We will also highlight important concerns about privacy, surveillance, and bias in big data, as well as the risks of over trust in machines, the challenges of transparency, the deskilling of healthcare practitioners, the way AI reframes healthcare, and the implications of AI for the distribution of power in healthcare ins
Physical rehabilitation exercises suggested by healthcare professionals can help recovery from various musculoskeletal disorders and prevent re-injury. However, patients' engagement tends to decrease over time without direct supervision, which is why there is a need for an automated monitoring system. In recent years, there has been great progress in quality assessment of physical rehabilitation exercises. Most of them only provide a binary classification if the performance is correct or incorrect, and a few provide a continuous score. This information is not sufficient for patients to improve their performance. In this work, we propose an algorithm for error classification of rehabilitation exercises, thus making the first step toward more detailed feedback to patients. We focus on skeleton-based exercise assessment, which utilizes human pose estimation to evaluate motion. Inspired by recent algorithms for quality assessment during rehabilitation exercises, we propose a Transformer-based model for the described classification. Our model is inspired by the HyperFormer method for human action recognition, and adapted to our problem and dataset. The evaluation is done on the KERAAL d
In recent years, the research of rehabilitation robot technology has become a hotspot in the field of rehabilitation medicine engineering and robotics. To assist active rehabilitation in patients with unilateral lower extremity injury, we propose a new self-service rehabilitation training method to control the injured lower extremity through its contralateral healthy upper limbs. Firstly, the movement data of upper limbs and lower limbs of healthy people in normal walking state are obtained by gait measurement experiment. Secondly, the eigenvectors of upper limb and lower limb movements in a single movement cycle are extracted respectively. Thirdly, the linear mapping relationship between the upper limbs movement and the lower limbs movement is identified using the least squares method. Finally, the simulation experiment of self-service rehabilitation training is implemented on MATLAB/Simulink. The results indicate that the identified linear mapping model can achieve good accuracy and adaptability. The self-service rehabilitation training method is effective for helping patients with unilateral limb injury to make rehabilitation training on themselves.
Recent studies indicate that Generative Pre-trained Transformer 4 with Vision (GPT-4V) outperforms human physicians in medical challenge tasks. However, these evaluations primarily focused on the accuracy of multi-choice questions alone. Our study extends the current scope by conducting a comprehensive analysis of GPT-4V's rationales of image comprehension, recall of medical knowledge, and step-by-step multimodal reasoning when solving New England Journal of Medicine (NEJM) Image Challenges - an imaging quiz designed to test the knowledge and diagnostic capabilities of medical professionals. Evaluation results confirmed that GPT-4V performs comparatively to human physicians regarding multi-choice accuracy (81.6% vs. 77.8%). GPT-4V also performs well in cases where physicians incorrectly answer, with over 78% accuracy. However, we discovered that GPT-4V frequently presents flawed rationales in cases where it makes the correct final choices (35.5%), most prominent in image comprehension (27.2%). Regardless of GPT-4V's high accuracy in multi-choice questions, our findings emphasize the necessity for further in-depth evaluations of its rationales before integrating such multimodal AI m
Rehabilitation robots are often used in game-like interactions for rehabilitation to increase a person's motivation to complete rehabilitation exercises. By adjusting exercise difficulty for a specific user throughout the exercise interaction, robots can maximize both the user's rehabilitation outcomes and the their motivation throughout the exercise. Previous approaches have assumed exercises have generic difficulty values that apply to all users equally, however, we identified that stroke survivors have varied and unique perceptions of exercise difficulty. For example, some stroke survivors found reaching vertically more difficult than reaching farther but lower while others found reaching farther more challenging than reaching vertically. In this paper, we formulate a causal tree-based method to calculate exercise difficulty based on the user's performance. We find that this approach accurately models exercise difficulty and provides a readily interpretable model of why that exercise is difficult for both users and caretakers.
Vision-based assessment can provide convenient and cost-effective evaluation in Traditional Chinese Medicine (TCM) rehabilitation training, where action quality assessment (AQA) from computer vision offers a promising solution. Existing automatic AQA frameworks for physical therapy typically rely on skeletal data captured from a single viewpoint, which is inefficient for TCM techniques such as acupuncture or Tuina that involve dense hand self-occlusion and complex hand-object interactions. To address these challenges, we propose CME-AQA, a cross-view, multimodal vision-based assessment framework that integrates visual-pose fusion to enhance understanding of environmental context and leverages both first-person and third-person videos during training to improve inference robustness. We collected two dual-view datasets, TCM-AQA61-A (Acupuncture) and TCM-AQA61-T (Tuina), each containing synchronized first-person and third-person recordings of 61 subjects with expert annotations. Experimental results show that our approach achieves superior or comparable mean performance against competitive baselines, achieving over 10% relative improvement in weighted F1 over the best competing method
One of the most frequent and severe aftermaths of a stroke is the loss of upper limb functionality. Therapy started in the sub-acute phase proved more effective, mainly when the patient participates actively. Recently, a novel set of rehabilitation and support robotic devices, known as supernumerary robotic limbs, have been introduced. This work investigates how a surface electromyography (sEMG) based control strategy would improve their usability in rehabilitation, limited so far by input interfaces requiring to subjects some level of residual mobility. After briefly introducing the phenomena hindering post-stroke sEMG and its use to control robotic hands, we describe a framework to acquire and interpret muscle signals of the forearm extensors. We applied it to drive a supernumerary robotic limb, the SoftHand-X, to provide Task-Specific Training (TST) in patients with sub-acute stroke. We propose and describe two algorithms to control the opening and closing of the robotic hand, with different levels of user agency and therapist control. We experimentally tested the feasibility of the proposed approach on four patients, followed by a therapist, to check their ability to operate th
Current medical retrieval-augmented generation (RAG) approaches overlook evidence-based medicine (EBM) principles, leading to two key gaps: (1) the lack of PICO alignment between queries and retrieved evidence, and (2) the absence of evidence hierarchy considerations during reranking. We present SR-RAG, an EBM-adapted GraphRAG framework that integrates the PICO framework into knowledge graph construction and retrieval, and proposes Bayesian Evidence Tier Reranking (BETR) to calibrate ranking scores by evidence grade without predefined weights. Validated in sports rehabilitation, we release a knowledge graph (357,844 nodes, 371,226 edges) and a benchmark of 1,637 QA pairs. SR-RAG achieves 0.812 evidence recall@10, 0.830 nugget coverage, 0.819 answer faithfulness, 0.882 semantic similarity, and 0.788 PICOT match accuracy, substantially outperforming five baselines. Five expert clinicians rated the system 4.66--4.84 on a 5-point Likert scale, and system rankings are preserved on a human-verified gold subset (n=80).
Advanced by rich perception and precise execution, robots possess immense potential to provide professional and customized rehabilitation exercises for patients with mobility impairments caused by strokes. Autonomous robotic rehabilitation significantly reduces human workloads in the long and tedious rehabilitation process. However, training a rehabilitation robot is challenging due to the data scarcity issue. This challenge arises from privacy concerns (e.g., the risk of leaking private disease and identity information of patients) during clinical data access and usage. Data from various patients and hospitals cannot be shared for adequate robot training, further compromising rehabilitation safety and limiting implementation scopes. To address this challenge, this work developed a novel federated joint learning (FJL) method to jointly train robots across hospitals. FJL also adopted a long short-term memory network (LSTM)-Transformer learning mechanism to effectively explore the complex tempo-spatial relations among patient mobility conditions and robotic rehabilitation motions. To validate FJL's effectiveness in training a robot network, a clinic-simulation combined experiment was
This paper tackles the challenge of automatically assessing physical rehabilitation exercises for patients who perform the exercises without clinician supervision. The objective is to provide a quality score to ensure correct performance and achieve desired results. To achieve this goal, a new graph-based model, the Dense Spatio-Temporal Graph Conv-GRU Network with Transformer, is introduced. This model combines a modified version of STGCN and transformer architectures for efficient handling of spatio-temporal data. The key idea is to consider skeleton data respecting its non-linear structure as a graph and detecting joints playing the main role in each rehabilitation exercise. Dense connections and GRU mechanisms are used to rapidly process large 3D skeleton inputs and effectively model temporal dynamics. The transformer encoder's attention mechanism focuses on relevant parts of the input sequence, making it useful for evaluating rehabilitation exercises. The evaluation of our proposed approach on the KIMORE and UI-PRMD datasets highlighted its potential, surpassing state-of-the-art methods in terms of accuracy and computational time. This resulted in faster and more accurate lear
This paper presents GARD, an upper limb end-effector rehabilitation device developed for stroke patients. GARD offers assistance force along or towards a 2D trajectory during physical therapy sessions. GARD employs a non-backdrivable mechanism with novel motor velocity-control-based algorithms, which offers superior control precision and stability. To our knowledge, this innovative technical route has not been previously explored in rehabilitation robotics. In alignment with the new design, GARD features two novel control algorithms: Implicit Euler Velocity Control (IEVC) algorithm and a generalized impedance control algorithm. These algorithms achieve O(n) runtime complexity for any arbitrary trajectory. The system has demonstrated a mean absolute error of 0.023mm in trajectory-following tasks and 0.14mm in trajectory-restricted free moving tasks. The proposed upper limb rehabilitation device offers all the functionalities of existing commercial devices with superior performance. Additionally, GARD provides unique functionalities such as area-restricted free moving and dynamic Motion Restriction Map interaction. This device holds strong potential for widespread clinical use, poten
Many neurological conditions, e.g., a stroke, can cause patients to experience upper limb (UL) motor impairments that hinder their daily activities. For such patients, while rehabilitation therapy is key for regaining autonomy and restoring mobility, its long-term nature entails ongoing time commitment and it is often not sufficiently engaging. Virtual reality (VR) can transform rehabilitation therapy into engaging game-like tasks that can be tailored to patient-specific activities, set goals, and provide rehabilitation assessment. Yet, most VR systems lack built-in methods to track progress over time and alter rehabilitation programs accordingly. We propose using arm kinematic modeling and capability maps to allow a VR system to understand a user's physical capability and limitation. Next, we suggest two use cases for the VR system to utilize the user's capability map for tailoring rehabilitation programs. Finally, for one use case, it is shown that the VR system can emphasize and assess the use of specific UL joints.
To allow the development and assessment of physical rehabilitation by an intelligent tutoring system, we propose a medical dataset of clinical patients carrying out low back-pain rehabilitation exercises and benchmark on state of the art human movement analysis algorithms. This dataset is valuable because it includes rehabilitation motions in a clinical setting with patients in their rehabilitation program. This paper introduces the Keraal dataset, a clinically collected dataset to enable intelligent tutoring systems (ITS) for rehabilitation. It addresses four challenges in exercise monitoring: motion assessment, error recognition, spatial localization, temporal localization
Medicine, including fields in healthcare and life sciences, has seen a flurry of quantum-related activities and experiments in the last few years (although biology and quantum theory have arguably been entangled ever since Schrödinger's cat). The initial focus was on biochemical and computational biology problems; recently, however, clinical and medical quantum solutions have drawn increasing interest. The rapid emergence of quantum computing in health and medicine necessitates a mapping of the landscape. In this review, clinical and medical proof-of-concept quantum computing applications are outlined and put into perspective. These consist of over 40 experimental and theoretical studies. The use case areas span genomics, clinical research and discovery, diagnostics, and treatments and interventions. Quantum machine learning (QML) in particular has rapidly evolved and shown to be competitive with classical benchmarks in recent medical research. Near-term QML algorithms have been trained with diverse clinical and real-world data sets. This includes studies in generating new molecular entities as drug candidates, diagnosing based on medical image classification, predicting patient pe
Currently, lower limb robotic rehabilitation is widely developed, However, the devices used so far seem to not have a uniform criteria for their design, because, on the contrary, each developed mechanism is often presented as if it does not take into account the criteria used in previous designs. On the other hand, the diagnosis of lower limb from robotic devices has been little studied. This chapter presents a guide for the design of robotic devices in diagnosis of lower limbs, taking into account the mobility of the human leg and the techniques used by physiotherapists in the execution of exercises and the rehabilitation of rehabilitation and diagnosis tests, as well as the recommendations made by various authors, among other aspects. The proposed guide is illustrated through a case study based on a parallel robot RPU+3UPS able to make movements that are applied during the processes of rehabilitation and diagnosis. The proposal presents advantages over some existing devices such as its load capacity that can support, and also allows you to restrict the movement in directions required by the rehabilitation and the diagnosis movements.
Disability is an important factor affecting todays society. At the same time, more and more sub-healthy people are sick due to reduced body functions and cognitive functions. Exercise rehabilitation is a kind of physical therapy, which can recover the motor ability, cognitive ability, and mental state of them through exercise. But the traditional exercise rehabilitation has some drawbacks so that people who need exercise rehabilitation cannot stick to it. Therefore, many researchers improved the drawbacks of traditional exercise rehabilitation by serious games for exercise rehabilitation. Although there were abundant achievements in the games, its relevant technologies and representative games are not be summarized systematically. To fill this gap, we introduced the significance of the convergence of exercise rehabilitation and serious games. Then, our paper sorted out the development of the games based on interaction mode between games and players. Besides, we analyzed the characteristics of different user groups and the specific functions of the games corresponding to them, and gave our classification based on this. Based on the classification, we reviewed related studies of the
Recent advances in data analytics and computer-aided diagnostics stimulate the vision of patient-centric precision healthcare, where treatment plans are customized based on the health records and needs of every patient. In physical rehabilitation, the progress in machine learning and the advent of affordable and reliable motion capture sensors have been conducive to the development of approaches for automated assessment of patient performance and progress toward functional recovery. The presented study reviews computational approaches for evaluating patient performance in rehabilitation programs using motion capture systems. Such approaches will play an important role in supplementing traditional rehabilitation assessment performed by trained clinicians, and in assisting patients participating in home-based rehabilitation. The reviewed computational methods for exercise evaluation are grouped into three main categories: discrete movement score, rule-based, and template-based approaches. The review places an emphasis on the application of machine learning methods for movement evaluation in rehabilitation. Related work in the literature on data representation, feature engineering, mo