Re: Mandel P, Wenzel M, Chun F, et al. Role of Local Treatment to the Prostate in Patients with De Novo Low-volume Metastatic Hormone-sensitive Prostate Cancer Receiving Androgen Receptor Pathway Inhibitors. Eur Urol Open Sci 2026;87:16-24: The PSA-response Window: Refining Local Therapy in ARPI-treated Low-volume mHSPC.