[Applications and challenges of ultra-high molecular weight polyethylene fibers in minimally invasive medical devices].

内容摘要

Ultra-high molecular weight polyethylene (UHMWPE) fiber has emerged as a critical material advancing the development of minimally invasive medical devices, owing to its exceptional specific strength, outstanding wear resistance, and inherent bio-inertia. We systematically review the current application landscape of UHMWPE fibers in minimally invasive medicine, highlighting their broad use in orthopedic sutures and fixation systems, reinforcement layers for cardiovascular interventional devices, cables to drive surgical robots, and materials in frontier neural interfaces. These applications underscore the material's core advantages across diverse scenarios. However, its broader clinical translation faces multiple challenges, including surface bio-inertia, long-term dynamic durability, difficulty in processing, and a lack of standardization. To address these challenges, this article delves into comprehensive strategies encompassing surface engineering, composite material development, structural optimization, and intelligent control algorithms. Looking forward, UHMWPE fibers are poised to evolve towards intelligence and functional integration. Through deep convergence with flexible electronics and data-driven research, coupled with the establishment of robust standardization systems, UHMWPE fibers are expected to play an even more pivotal role in the next generation of advanced minimally invasive medical devices, ultimately propelling the field towards greater precision and personalization. 超高分子量聚乙烯（UHMWPE）纤维凭借其超高的比强度、卓越的耐磨性及固有的生物惰性，已成为推动微创医疗器械发展的关键材料之一。本综述系统梳理了UHMWPE纤维在微创医疗领域的应用现状，涵盖其在骨科缝合线与固定系统、心血管介入器械增强层、手术机器人驱动缆索以及前沿神经介入接口中的广泛应用，彰显了其在不同场景下的核心优势。然而，其进一步临床应用仍面临表面生物惰性、长期动态耐久性、加工技术壁垒及标准化缺失等多重挑战。针对这些挑战，本文深入探讨了包括表面工程、复合材料开发、结构优化与智能控制算法在内的综合性应对策略。展望未来，UHMWPE纤维将向智能化、功能集成化方向演进，通过与柔性电子、数据驱动研发的深度融合，以及建立完善的标准化体系，有望在下一代高端微创医疗器械中扮演更为核心的角色，最终推动微创手术向更精准、更个性化的方向发展。.